Search Results - "Greasley PJ"

Localization of the therapeutic targets for endothelin receptor antagonists and sodium-glucose co-transporter 2 inhibitors in the chronic liver disease, primary sclerosing cholangitis.

Authors: Kuc RE Paterson AL Williams TL et al.

Source: Frontiers in pharmacology [Front Pharmacol] 2025 Sep 29; Vol. 16, pp. 1680875. Date of Electronic Publication: 2025 Sep 29 (Print Publication: 2025).

Publication Type: Journal Article

Journal Info: Publisher: Frontiers Media] Country of Publication: Switzerland NLM ID: 101548923 Publication Model: eCollection Cited Medium: Print ISSN: 1663-9812 (Print) Linking ISSN: 16639812 NLM ISO Abbreviation: Front Pharmacol Subsets: PubMed not MEDLINE

Kidney transcriptomics signature of prospective rapid diabetic kidney disease progression.

Authors: Acoba D Levin A Witasp A et al.

Source: BMC nephrology [BMC Nephrol] 2025 Aug 31; Vol. 26 (1), pp. 504. Date of Electronic Publication: 2025 Aug 31.

Publication Type: Journal Article

Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 100967793 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2369 (Electronic) Linking ISSN: 14712369 NLM ISO Abbreviation: BMC Nephrol Subsets: MEDLINE

Association of Urinary EGF with Kidney Outcomes and Effects of Sodium-Glucose Cotransporter 2 Inhibition.

Authors: Moedt E Koshino A Jongs N et al.

Source: Journal of the American Society of Nephrology : JASN [J Am Soc Nephrol] 2026 Apr 02. Date of Electronic Publication: 2026 Apr 02.

Publication Type: Journal Article

Journal Info: Publisher: Wolters Kluwer Health, on behalf of the American Society of Nephrology Country of Publication: United States NLM ID: 9013836 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1533-3450 (Electronic) Linking ISSN: 10466673 NLM ISO Abbreviation: J Am Soc Nephrol Subsets: MEDLINE

Protein profiles and associated biological pathways among different aetiologies of chronic kidney disease: new insights from DAPA-CKD.

Authors: de la Rambelje MA Beldhuis IE Heerspink HJL et al.

Source: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association [Nephrol Dial Transplant] 2026 Feb 27; Vol. 41 (3), pp. 545-555.

Publication Type: Journal Article; Randomized Controlled Trial

Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 8706402 Publication Model: Print Cited Medium: Internet ISSN: 1460-2385 (Electronic) Linking ISSN: 09310509 NLM ISO Abbreviation: Nephrol Dial Transplant Subsets: MEDLINE

Kinetics of endothelin-1 and effect selective ETA antagonism on ETB activation: a mathematical modeling analysis.

Authors: Hallow KM Greasley PJ Heerspink HJL et al.

Source: Frontiers in pharmacology [Front Pharmacol] 2024 Nov 26; Vol. 15, pp. 1332388. Date of Electronic Publication: 2024 Nov 26 (Print Publication: 2024).

Publication Type: Journal Article

Journal Info: Publisher: Frontiers Media] Country of Publication: Switzerland NLM ID: 101548923 Publication Model: eCollection Cited Medium: Print ISSN: 1663-9812 (Print) Linking ISSN: 16639812 NLM ISO Abbreviation: Front Pharmacol Subsets: PubMed not MEDLINE

The role of venous capacity in fluid retention with endothelin A antagonism: Mathematical modelling of the RADAR trial.

Authors: Yu H Greasley PJ Lambers Heerspink HJ et al.

Source: British journal of pharmacology [Br J Pharmacol] 2024 Nov; Vol. 181 (22), pp. 4693-4707. Date of Electronic Publication: 2024 Aug 19.

Publication Type: Journal Article; Randomized Controlled Trial

Journal Info: Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5381 (Electronic) Linking ISSN: 00071188 NLM ISO Abbreviation: Br J Pharmacol Subsets: MEDLINE

Proteins and signalling pathways targeted by dapagliflozin and finerenone: Insights from DAPA-CKD and FIGARO-DKD.

Authors: de la Rambelje MA Voors AA Greasley PJ et al.

Source: Diabetes, obesity & metabolism [Diabetes Obes Metab] 2026 Jan; Vol. 28 (1), pp. 750-753. Date of Electronic Publication: 2025 Oct 13.

Publication Type: Letter

Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 100883645 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1463-1326 (Electronic) Linking ISSN: 14628902 NLM ISO Abbreviation: Diabetes Obes Metab Subsets: MEDLINE; In Process

From Plan to Pivot: How Model-Informed Drug Development Shaped the Dose Strategy of the Zibotentan/Dapagliflozin ZENITH Trials.

Authors: Mercier AK Ueckert S Sunnåker M et al.

Source: Clinical pharmacology and therapeutics [Clin Pharmacol Ther] 2024 Sep; Vol. 116 (3), pp. 653-664. Date of Electronic Publication: 2024 Jul 03.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 0372741 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-6535 (Electronic) Linking ISSN: 00099236 NLM ISO Abbreviation: Clin Pharmacol Ther Subsets: MEDLINE

Gastric Bypass vs Diet and Cardiovascular Risk Factors: A Nonrandomized Controlled Trial.

Authors: Karlsson C Johnson LK Greasley PJ et al.

Source: JAMA surgery [JAMA Surg] 2024 Sep 01; Vol. 159 (9), pp. 971-980.

Publication Type: Comparative Study; Controlled Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Medical Association Country of Publication: United States NLM ID: 101589553 Publication Model: Print Cited Medium: Internet ISSN: 2168-6262 (Electronic) Linking ISSN: 21686254 NLM ISO Abbreviation: JAMA Surg Subsets: MEDLINE

Co-localization of the sodium-glucose co-transporter-2 channel (SGLT-2) with endothelin ETA and ETB receptors in human cardiorenal tissue.

Authors: Williams TL Kuc RE Paterson AL et al.

Source: Bioscience reports [Biosci Rep] 2024 Jun 26; Vol. 44 (6).

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Portland Press on behalf of the Biochemical Society Country of Publication: England NLM ID: 8102797 Publication Model: Print Cited Medium: Internet ISSN: 1573-4935 (Electronic) Linking ISSN: 01448463 NLM ISO Abbreviation: Biosci Rep Subsets: MEDLINE

Targeting the endothelium by combining endothelin-1 antagonism and SGLT-2 inhibition: better together?

Authors: Ambery P Greasley PJ Menzies RI et al.

Source: Clinical science (London, England : 1979) [Clin Sci (Lond)] 2024 Jun 05; Vol. 138 (11), pp. 687-697.

Publication Type: Journal Article; Review; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Portland Press on behalf of the Medical Research Society and the Biochemical Society Country of Publication: England NLM ID: 7905731 Publication Model: Print Cited Medium: Internet ISSN: 1470-8736 (Electronic) Linking ISSN: 01435221 NLM ISO Abbreviation: Clin Sci (Lond) Subsets: MEDLINE

Effects of combined treatment with zibotentan and dapagliflozin compared to dapagliflozin alone in patients with diabetic and non-diabetic chronic kidney disease.

Authors: Wasehuus V Smeijer JD Ambery P et al.

Source: Diabetes, obesity & metabolism [Diabetes Obes Metab] 2025 Aug; Vol. 27 (8), pp. 4311-4319. Date of Electronic Publication: 2025 May 21.

Publication Type: Journal Article; Randomized Controlled Trial; Multicenter Study; Clinical Trial, Phase II; Comparative Study

Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 100883645 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1463-1326 (Electronic) Linking ISSN: 14628902 NLM ISO Abbreviation: Diabetes Obes Metab Subsets: MEDLINE

Effects of dapagliflozin on sodium excretion, blood pressure and volume status in patients with type 2 diabetes and/or chronic kidney disease: The DAPASALT trial.

Authors: Beernink JM Jongs N Mosterd CM et al.

Source: Diabetes, obesity & metabolism [Diabetes Obes Metab] 2025 Aug; Vol. 27 (8), pp. 4415-4426. Date of Electronic Publication: 2025 May 30.

Publication Type: Clinical Trial, Phase IV; Journal Article; Multicenter Study

Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 100883645 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1463-1326 (Electronic) Linking ISSN: 14628902 NLM ISO Abbreviation: Diabetes Obes Metab Subsets: MEDLINE

A multi-omics microbiome signature is associated with the benefits of gastric bypass surgery and is differentiated from diet induced weight loss through 2 years of follow-up.

Authors: Gopalakrishnan V Kumar C Robertsen I et al.

Source: Mucosal immunology [Mucosal Immunol] 2025 Aug; Vol. 18 (4), pp. 825-835. Date of Electronic Publication: 2025 Apr 11.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 101299742 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1935-3456 (Electronic) Linking ISSN: 19330219 NLM ISO Abbreviation: Mucosal Immunol Subsets: MEDLINE

Efficacy and safety of zibotentan and dapagliflozin in patients with chronic kidney disease: study design and baseline characteristics of the ZENITH-CKD trial.

Authors: Heerspink HJL Greasley PJ Ahlström C et al.

Source: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association [Nephrol Dial Transplant] 2024 Feb 28; Vol. 39 (3), pp. 414-425.

Publication Type: Journal Article; Clinical Trial Protocol

Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 8706402 Publication Model: Print Cited Medium: Internet ISSN: 1460-2385 (Electronic) Linking ISSN: 09310509 NLM ISO Abbreviation: Nephrol Dial Transplant Subsets: MEDLINE

Potential Underlying Mechanisms Explaining the Cardiorenal Benefits of Sodium-Glucose Cotransporter 2 Inhibitors.

Authors: Verma S Mudaliar S Greasley PJ

Source: Advances in therapy [Adv Ther] 2024 Jan; Vol. 41 (1), pp. 92-112. Date of Electronic Publication: 2023 Nov 09.

Publication Type: Journal Article; Review; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Health Communications Inc Country of Publication: United States NLM ID: 8611864 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1865-8652 (Electronic) Linking ISSN: 0741238X NLM ISO Abbreviation: Adv Ther

Effects of dapagliflozin and dapagliflozin-saxagliptin on erythropoiesis, iron and inflammation markers in patients with type 2 diabetes and chronic kidney disease: data from the DELIGHT trial.

Authors: Koshino A Neuen BL Jongs N et al.

Source: Cardiovascular diabetology [Cardiovasc Diabetol] 2023 Nov 28; Vol. 22 (1), pp. 330. Date of Electronic Publication: 2023 Nov 28.

Publication Type: Randomized Controlled Trial; Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101147637 Publication Model: Electronic Cited Medium: Internet ISSN: 1475-2840 (Electronic) Linking ISSN: 14752840 NLM ISO Abbreviation: Cardiovasc Diabetol Subsets: MEDLINE

Proteinuria as an End Point in Clinical Trials of Focal Segmental Glomerulosclerosis.

Authors: Mariani LH Trachtman H Thompson A et al.

Source: American journal of kidney diseases : the official journal of the National Kidney Foundation [Am J Kidney Dis] 2025 May; Vol. 85 (5), pp. 610-617. Date of Electronic Publication: 2024 Oct 23.

Publication Type: Journal Article; Review

Journal Info: Publisher: W.B. Saunders Country of Publication: United States NLM ID: 8110075 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1523-6838 (Electronic) Linking ISSN: 02726386 NLM ISO Abbreviation: Am J Kidney Dis Subsets: MEDLINE

The sodium glucose co-transporter 2 inhibitor dapagliflozin ameliorates the fluid-retaining effect of the endothelin A receptor antagonist zibotentan.

Authors: Veenit V Heerspink HJL Ahlström C et al.

Source: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association [Nephrol Dial Transplant] 2023 Sep 29; Vol. 38 (10), pp. 2289-2297.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 8706402 Publication Model: Print Cited Medium: Internet ISSN: 1460-2385 (Electronic) Linking ISSN: 09310509 NLM ISO Abbreviation: Nephrol Dial Transplant Subsets: MEDLINE

Effect of AZD9977 and spironolactone on serum potassium in heart failure with preserved or mildly reduced ejection fraction, and renal impairment: A randomized trial.

Authors: Squire IB Gabrielsen A Greasley PJ et al.

Source: Clinical and translational science [Clin Transl Sci] 2022 Oct; Vol. 15 (10), pp. 2493-2504. Date of Electronic Publication: 2022 Aug 20.

Publication Type: Randomized Controlled Trial; Clinical Trial, Phase I; Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: WileyBlackwell Pub Country of Publication: United States NLM ID: 101474067 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1752-8062 (Electronic) Linking ISSN: 17528054 NLM ISO Abbreviation: Clin Transl Sci Subsets: MEDLINE