Search Results - "Harding FA"

Sequential JAK inhibition enhances antitumor immunity after combined anti-PD-1 and anti-CTLA4.

Authors: Arias-Badia M Chen P Lwin YM et al.

Source: JCI insight [JCI Insight] 2025 Feb 27; Vol. 10 (7). Date of Electronic Publication: 2025 Feb 27.

Publication Type: Journal Article; Research Support, N.I.H., Extramural

Journal Info: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 101676073 Publication Model: Electronic Cited Medium: Internet ISSN: 2379-3708 (Electronic) Linking ISSN: 23793708 NLM ISO Abbreviation: JCI Insight Subsets: MEDLINE

Targeting the aminopeptidase ERAP enhances antitumor immunity by disrupting the NKG2A-HLA-E inhibitory checkpoint.

Authors: Tsao HW Anderson S Finn KJ et al.

Source: Immunity [Immunity] 2024 Dec 10; Vol. 57 (12), pp. 2863-2878.e12. Date of Electronic Publication: 2024 Nov 18.

Publication Type: Journal Article

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 9432918 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4180 (Electronic) Linking ISSN: 10747613 NLM ISO Abbreviation: Immunity Subsets: MEDLINE

Design, creation and in vitro testing of a reduced immunogenicity humanized anti-CD25 monoclonal antibody that retains functional activity.

Authors: Stickler M Reddy A Xiong JM et al.

Source: Protein engineering, design & selection : PEDS [Protein Eng Des Sel] 2019 Dec 31; Vol. 32 (12), pp. 543-554.

Publication Type: Journal Article

Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 101186484 Publication Model: Print Cited Medium: Internet ISSN: 1741-0134 (Electronic) Linking ISSN: 17410126 NLM ISO Abbreviation: Protein Eng Des Sel Subsets: MEDLINE

The human G1m1 allotype associates with CD4+ T-cell responsiveness to a highly conserved IgG1 constant region peptide and confers an asparaginyl endopeptidase cleavage site.

Authors: Stickler MM Reddy A Xiong JM et al.

Source: Genes and immunity [Genes Immun] 2011 Apr; Vol. 12 (3), pp. 213-21. Date of Electronic Publication: 2011 Feb 17.

Publication Type: Journal Article

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 100953417 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5470 (Electronic) Linking ISSN: 14664879 NLM ISO Abbreviation: Genes Immun Subsets: MEDLINE

An in vitro human cell-based assay to rank the relative immunogenicity of proteins.

Authors: Stickler M Rochanayon N Razo OJ et al.

Source: Toxicological sciences : an official journal of the Society of Toxicology [Toxicol Sci] 2004 Feb; Vol. 77 (2), pp. 280-9. Date of Electronic Publication: 2003 Dec 22.

Publication Type: Journal Article

Journal Info: Publisher: Oxford University Press Country of Publication: United States NLM ID: 9805461 Publication Model: Print-Electronic Cited Medium: Print ISSN: 1096-6080 (Print) Linking ISSN: 10960929 NLM ISO Abbreviation: Toxicol Sci Subsets: MEDLINE

The HLA-DR2 haplotype is associated with an increased proliferative response to the immunodominant CD4(+) T-cell epitope in human interferon-beta.

Authors: Stickler M Valdes AM Gebel W et al.

Source: Genes and immunity [Genes Immun] 2004 Jan; Vol. 5 (1), pp. 1-7.

Publication Type: Journal Article

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 100953417 Publication Model: Print Cited Medium: Print ISSN: 1466-4879 (Print) Linking ISSN: 14664879 NLM ISO Abbreviation: Genes Immun Subsets: MEDLINE

Enhanced immunogenicity of a functional enzyme by T cell epitope modification.

Authors: Mucha JM Stickler MM Poulose AJ et al.

Source: BMC immunology [BMC Immunol] 2002; Vol. 3, pp. 2. Date of Electronic Publication: 2002 Jan 25.

Publication Type: Journal Article

Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 100966980 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1471-2172 (Electronic) Linking ISSN: 14712172 NLM ISO Abbreviation: BMC Immunol Subsets: MEDLINE

Murinization and H Chain Isotype Matching of the Anti-GITR Antibody DTA-1 Reduces Immunogenicity-Mediated Anaphylaxis in C57BL/6 Mice.

Authors: Belmar NA Chan SW Fox MI et al.

Source: Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2017 Jun 01; Vol. 198 (11), pp. 4502-4512. Date of Electronic Publication: 2017 Apr 26.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 2985117R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1550-6606 (Electronic) Linking ISSN: 00221767 NLM ISO Abbreviation: J Immunol Subsets: MEDLINE

The immunogenicity of humanized and fully human antibodies: residual immunogenicity resides in the CDR regions.

Authors: Harding FA Stickler MM Razo J et al.

Source: MAbs [MAbs] 2010 May-Jun; Vol. 2 (3), pp. 256-65. Date of Electronic Publication: 2010 May 01.

Publication Type: Journal Article

Journal Info: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101479829 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1942-0870 (Electronic) Linking ISSN: 19420862 NLM ISO Abbreviation: MAbs Subsets: MEDLINE

A beta-lactamase with reduced immunogenicity for the targeted delivery of chemotherapeutics using antibody-directed enzyme prodrug therapy.

Authors: Harding FA Liu AD Stickler M et al.

Source: Molecular cancer therapeutics [Mol Cancer Ther] 2005 Nov; Vol. 4 (11), pp. 1791-800.

Publication Type: Journal Article

Journal Info: Publisher: American Association for Cancer Research, Inc Country of Publication: United States NLM ID: 101132535 Publication Model: Print Cited Medium: Print ISSN: 1535-7163 (Print) Linking ISSN: 15357163 NLM ISO Abbreviation: Mol Cancer Ther Subsets: MEDLINE

Elimination of an immunodominant CD4+ T cell epitope in human IFN-beta does not result in an in vivo response directed at the subdominant epitope.

Authors: Yeung VP Chang J Miller J et al.

Source: Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2004 Jun 01; Vol. 172 (11), pp. 6658-65.

Publication Type: Journal Article

Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 2985117R Publication Model: Print Cited Medium: Print ISSN: 0022-1767 (Print) Linking ISSN: 00221767 NLM ISO Abbreviation: J Immunol Subsets: MEDLINE

Human population-based identification of CD4(+) T-cell peptide epitope determinants.

Authors: Stickler M Chin R Faravashi N et al.

Source: Journal of immunological methods [J Immunol Methods] 2003 Oct 01; Vol. 281 (1-2), pp. 95-108.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 1305440 Publication Model: Print Cited Medium: Print ISSN: 0022-1759 (Print) Linking ISSN: 00221759 NLM ISO Abbreviation: J Immunol Methods Subsets: MEDLINE

CD4+ T-cell epitope determination using unexposed human donor peripheral blood mononuclear cells.

Authors: Stickler MM Estell DA Harding FA

Source: Journal of immunotherapy (Hagerstown, Md. : 1997) [J Immunother] 2000 Nov-Dec; Vol. 23 (6), pp. 654-60.

Publication Type: Evaluation Study; Journal Article

Journal Info: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 9706083 Publication Model: Print Cited Medium: Print ISSN: 1524-9557 (Print) Linking ISSN: 15249557 NLM ISO Abbreviation: J Immunother Subsets: MEDLINE

Class switching in human immunoglobulin transgenic mice.

Authors: Harding FA Lonberg N

Source: Annals of the New York Academy of Sciences [Ann N Y Acad Sci] 1995 Sep 29; Vol. 764, pp. 536-46.

Publication Type: Journal Article

Journal Info: Publisher: New York Academy of Sciences Country of Publication: United States NLM ID: 7506858 Publication Model: Print Cited Medium: Print ISSN: 0077-8923 (Print) Linking ISSN: 00778923 NLM ISO Abbreviation: Ann N Y Acad Sci Subsets: MEDLINE

Antigen-specific human antibodies from mice comprising four distinct genetic modifications.

Authors: Lonberg N Taylor LD Harding FA et al.

Source: Nature [Nature] 1994 Apr 28; Vol. 368 (6474), pp. 856-9.

Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print Cited Medium: Print ISSN: 0028-0836 (Print) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE

MHC restriction of T-cell proliferative responses in Xenopus.

Authors: Harding FA Flajnik MF Cohen N

Source: Developmental and comparative immunology [Dev Comp Immunol] 1993 Sep-Oct; Vol. 17 (5), pp. 425-37.

Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.

Journal Info: Publisher: Elsevier Science Country of Publication: United States NLM ID: 7708205 Publication Model: Print Cited Medium: Print ISSN: 0145-305X (Print) Linking ISSN: 0145305X NLM ISO Abbreviation: Dev Comp Immunol Subsets: MEDLINE

CD28-B7 interactions allow the induction of CD8+ cytotoxic T lymphocytes in the absence of exogenous help.

Authors: Harding FA Allison JP

Source: The Journal of experimental medicine [J Exp Med] 1993 Jun 01; Vol. 177 (6), pp. 1791-6.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

Journal Info: Publisher: Rockefeller University Press Country of Publication: United States NLM ID: 2985109R Publication Model: Print Cited Medium: Print ISSN: 0022-1007 (Print) Linking ISSN: 00221007 NLM ISO Abbreviation: J Exp Med Subsets: MEDLINE

Immune system activation associated with a naturally occurring infection in Xenopus laevis.

Authors: Haynes L Harding FA Koniski AD et al.

Source: Developmental and comparative immunology [Dev Comp Immunol] 1992 Nov-Dec; Vol. 16 (6), pp. 453-62.

Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.

Journal Info: Publisher: Elsevier Science Country of Publication: United States NLM ID: 7708205 Publication Model: Print Cited Medium: Print ISSN: 0145-305X (Print) Linking ISSN: 0145305X NLM ISO Abbreviation: Dev Comp Immunol Subsets: MEDLINE

CD28-mediated signalling co-stimulates murine T cells and prevents induction of anergy in T-cell clones.

Authors: Harding FA McArthur JG Gross JA et al.

Source: Nature [Nature] 1992 Apr 16; Vol. 356 (6370), pp. 607-9.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print Cited Medium: Print ISSN: 0028-0836 (Print) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE

Evolutionary development of immunoglobulin gene diversity.

Authors: Litman GW Amemiya CT Harding FA et al.

Source: Advances in experimental medicine and biology [Adv Exp Med Biol] 1991; Vol. 292, pp. 11-7.

Publication Type: Journal Article; Review

Journal Info: Publisher: Kluwer Academic/Plenum Publishers Country of Publication: United States NLM ID: 0121103 Publication Model: Print Cited Medium: Print ISSN: 0065-2598 (Print) Linking ISSN: 00652598 NLM ISO Abbreviation: Adv Exp Med Biol Subsets: MEDLINE