Search Results - "Harding TC"

BRCA1 secondary splice-site mutations drive exon-skipping and PARP inhibitor resistance.

Authors: Nesic K Krais JJ Wang Y et al.

Corporate Authors: Nesic K Krais JJ Wang Y et al.

Source: Molecular cancer [Mol Cancer] 2024 Aug 05; Vol. 23 (1), pp. 158. Date of Electronic Publication: 2024 Aug 05.

Publication Type: Letter

Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101147698 Publication Model: Electronic Cited Medium: Internet ISSN: 1476-4598 (Electronic) Linking ISSN: 14764598 NLM ISO Abbreviation: Mol Cancer Subsets: MEDLINE

Fibroblast activation protein targeted radiotherapy induces an immunogenic tumor microenvironment and enhances the efficacy of PD-1 immune checkpoint inhibition.

Authors: Zboralski D Osterkamp F Christensen E et al.

Source: European journal of nuclear medicine and molecular imaging [Eur J Nucl Med Mol Imaging] 2023 Jul; Vol. 50 (9), pp. 2621-2635. Date of Electronic Publication: 2023 Apr 22.

Publication Type: Journal Article

Journal Info: Publisher: Springer-Verlag Berlin Country of Publication: Germany NLM ID: 101140988 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1619-7089 (Electronic) Linking ISSN: 16197070 NLM ISO Abbreviation: Eur J Nucl Med Mol Imaging Subsets: MEDLINE

Clinical Pharmacokinetics and Pharmacodynamics of Rucaparib.

Authors: Liao M Beltman J Giordano H et al.

Source: Clinical pharmacokinetics [Clin Pharmacokinet] 2022 Nov; Vol. 61 (11), pp. 1477-1493. Date of Electronic Publication: 2022 Sep 15.

Publication Type: Journal Article; Review

Journal Info: Publisher: Adis, part of Springer Science+Business Media Country of Publication: Switzerland NLM ID: 7606849 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1179-1926 (Electronic) Linking ISSN: 03125963 NLM ISO Abbreviation: Clin Pharmacokinet Subsets: MEDLINE

Preclinical evaluation of FAP-2286 for fibroblast activation protein targeted radionuclide imaging and therapy.

Authors: Zboralski D Hoehne A Bredenbeck A et al.

Source: European journal of nuclear medicine and molecular imaging [Eur J Nucl Med Mol Imaging] 2022 Sep; Vol. 49 (11), pp. 3651-3667. Date of Electronic Publication: 2022 May 24.

Publication Type: Journal Article

Journal Info: Publisher: Springer-Verlag Berlin Country of Publication: Germany NLM ID: 101140988 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1619-7089 (Electronic) Linking ISSN: 16197070 NLM ISO Abbreviation: Eur J Nucl Med Mol Imaging Subsets: MEDLINE

Population pharmacokinetics of rucaparib in patients with advanced ovarian cancer or other solid tumors.

Authors: Green ML Ma SC Goble S et al.

Source: Cancer chemotherapy and pharmacology [Cancer Chemother Pharmacol] 2022 May; Vol. 89 (5), pp. 671-682. Date of Electronic Publication: 2022 Apr 10.

Publication Type: Journal Article

Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 7806519 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0843 (Electronic) Linking ISSN: 03445704 NLM ISO Abbreviation: Cancer Chemother Pharmacol Subsets: MEDLINE

Evaluation of in vitro absorption, distribution, metabolism, and excretion and assessment of drug-drug interaction of rucaparib, an orally potent poly(ADP-ribose) polymerase inhibitor.

Authors: Liao M Jaw-Tsai S Beltman J et al.

Source: Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 2020 Sep; Vol. 50 (9), pp. 1032-1042. Date of Electronic Publication: 2020 Mar 18.

Publication Type: Journal Article

Journal Info: Publisher: Informa Healthcare Country of Publication: England NLM ID: 1306665 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1366-5928 (Electronic) Linking ISSN: 00498254 NLM ISO Abbreviation: Xenobiotica Subsets: MEDLINE

BRCA1 secondary splice-site mutations drive exon-skipping and PARP inhibitor resistance.

Authors: Nesic K Krais JJ Vandenberg CJ et al.

Corporate Authors: Nesic K Krais JJ Vandenberg CJ et al.

Source: MedRxiv : the preprint server for health sciences [medRxiv] 2023 Aug 28. Date of Electronic Publication: 2023 Aug 28.

Publication Type: Preprint; Journal Article

Journal Info: Country of Publication: United States NLM ID: 101767986 Publication Model: Electronic Cited Medium: Internet NLM ISO Abbreviation: medRxiv Subsets: PubMed not MEDLINE

Cell-Free DNA Next-Generation Sequencing Prediction of Response and Resistance to Third-Generation EGFR Inhibitor.

Authors: Helman E Nguyen M Karlovich CA et al.

Source: Clinical lung cancer [Clin Lung Cancer] 2018 Nov; Vol. 19 (6), pp. 518-530.e7. Date of Electronic Publication: 2018 Aug 07.

Publication Type: Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 100893225 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1938-0690 (Electronic) Linking ISSN: 15257304 NLM ISO Abbreviation: Clin Lung Cancer Subsets: MEDLINE

Methylation of all BRCA1 copies predicts response to the PARP inhibitor rucaparib in ovarian carcinoma.

Authors: Kondrashova O Topp M Nesic K et al.

Corporate Authors: Kondrashova O Topp M Nesic K et al.

Source: Nature communications [Nat Commun] 2018 Sep 28; Vol. 9 (1), pp. 3970. Date of Electronic Publication: 2018 Sep 28.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

The Multi-Kinase Inhibitor Lucitanib Enhances the Antitumor Activity of Coinhibitory and Costimulatory Immune Pathway Modulators in Syngeneic Models.

Authors: Robillard L Liao M Nguyen M et al.

Source: Journal of immunotherapy (Hagerstown, Md. : 1997) [J Immunother] 2022 Oct 01; Vol. 45 (8), pp. 335-348. Date of Electronic Publication: 2022 Jul 06.

Publication Type: Journal Article

Journal Info: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 9706083 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1537-4513 (Electronic) Linking ISSN: 15249557 NLM ISO Abbreviation: J Immunother Subsets: MEDLINE

Corrigendum: Circulating tumour DNA profiling reveals heterogeneity of EGFR inhibitor resistance mechanisms in lung cancer patients.

Authors: Chabon JJ Simmons AD Lovejoy AF et al.

Source: Nature communications [Nat Commun] 2016 Nov 14; Vol. 7, pp. 13513. Date of Electronic Publication: 2016 Nov 14.

Publication Type: Journal Article; Published Erratum

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: PubMed not MEDLINE

Circulating tumour DNA profiling reveals heterogeneity of EGFR inhibitor resistance mechanisms in lung cancer patients.

Authors: Chabon JJ Simmons AD Lovejoy AF et al.

Source: Nature communications [Nat Commun] 2016 Jun 10; Vol. 7, pp. 11815. Date of Electronic Publication: 2016 Jun 10.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

Characterization of a RAD51C-silenced high-grade serous ovarian cancer model during development of PARP inhibitor resistance.

Authors: Hurley RM McGehee CD Nesic K et al.

Source: NAR cancer [NAR Cancer] 2021 Jul 09; Vol. 3 (3), pp. zcab028. Date of Electronic Publication: 2021 Jul 09 (Print Publication: 2021).

Publication Type: Journal Article

Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 101769553 Publication Model: eCollection Cited Medium: Internet ISSN: 2632-8674 (Electronic) Linking ISSN: 26328674 NLM ISO Abbreviation: NAR Cancer Subsets: PubMed not MEDLINE

BET, SRC, and BCL2 family inhibitors are synergistic drug combinations with PARP inhibitors in ovarian cancer.

Authors: Lui GYL Shaw R Schaub FX et al.

Source: EBioMedicine [EBioMedicine] 2020 Oct; Vol. 60, pp. 102988. Date of Electronic Publication: 2020 Sep 11.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier B.V Country of Publication: Netherlands NLM ID: 101647039 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2352-3964 (Electronic) Linking ISSN: 23523964 NLM ISO Abbreviation: EBioMedicine Subsets: MEDLINE

Blockade of nonhormonal fibroblast growth factors by FP-1039 inhibits growth of multiple types of cancer.

Authors: Harding TC Long L Palencia S et al.

Source: Science translational medicine [Sci Transl Med] 2013 Mar 27; Vol. 5 (178), pp. 178ra39.

Publication Type: Journal Article

Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE

Antibody responses to galectin-8, TARP and TRAP1 in prostate cancer patients treated with a GM-CSF-secreting cellular immunotherapy.

Authors: Nguyen MC Tu GH Koprivnikar KE et al.

Source: Cancer immunology, immunotherapy : CII [Cancer Immunol Immunother] 2010 Sep; Vol. 59 (9), pp. 1313-23. Date of Electronic Publication: 2010 May 25.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 8605732 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0851 (Electronic) Linking ISSN: 03407004 NLM ISO Abbreviation: Cancer Immunol Immunother Subsets: MEDLINE

An antibody delivery system for regulated expression of therapeutic levels of monoclonal antibodies in vivo.

Authors: Fang J Yi S Simmons A et al.

Source: Molecular therapy : the journal of the American Society of Gene Therapy [Mol Ther] 2007 Jun; Vol. 15 (6), pp. 1153-9. Date of Electronic Publication: 2007 Mar 20.

Publication Type: Journal Article

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 100890581 Publication Model: Print-Electronic Cited Medium: Print ISSN: 1525-0016 (Print) Linking ISSN: 15250016 NLM ISO Abbreviation: Mol Ther Subsets: MEDLINE

Rapamycin-regulated control of antiangiogenic tumor therapy following rAAV-mediated gene transfer.

Authors: Nguyen M Huan-Tu G Gonzalez-Edick M et al.

Source: Molecular therapy : the journal of the American Society of Gene Therapy [Mol Ther] 2007 May; Vol. 15 (5), pp. 912-20. Date of Electronic Publication: 2007 Jan 23.

Publication Type: Journal Article

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 100890581 Publication Model: Print-Electronic Cited Medium: Print ISSN: 1525-0016 (Print) Linking ISSN: 15250016 NLM ISO Abbreviation: Mol Ther Subsets: MEDLINE

AAV serotype 8-mediated gene delivery of a soluble VEGF receptor to the CNS for the treatment of glioblastoma.

Authors: Harding TC Lalani AS Roberts BN et al.

Source: Molecular therapy : the journal of the American Society of Gene Therapy [Mol Ther] 2006 May; Vol. 13 (5), pp. 956-66. Date of Electronic Publication: 2006 Mar 31.

Publication Type: Journal Article

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 100890581 Publication Model: Print-Electronic Cited Medium: Print ISSN: 1525-0016 (Print) Linking ISSN: 15250016 NLM ISO Abbreviation: Mol Ther Subsets: MEDLINE

Intravenous administration of an AAV-2 vector for the expression of factor IX in mice and a dog model of hemophilia B.

Authors: Harding TC Koprivnikar KE Tu GH et al.

Source: Gene therapy [Gene Ther] 2004 Jan; Vol. 11 (2), pp. 204-13.

Publication Type: Comparative Study; Journal Article

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 9421525 Publication Model: Print Cited Medium: Print ISSN: 0969-7128 (Print) Linking ISSN: 09697128 NLM ISO Abbreviation: Gene Ther Subsets: MEDLINE