Search Results - "Hardwick JS"

SCoTCH-seq reveals that 5-hydroxymethylcytosine encodes regulatory information across DNA strands.

Authors: Hardwick JS Dhir S Kirchner A et al.

Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2025 Aug 05; Vol. 122 (31), pp. e2512204122. Date of Electronic Publication: 2025 Jul 31.

Publication Type: Journal Article

Journal Info: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

An LNA-amide modification that enhances the cell uptake and activity of phosphorothioate exon-skipping oligonucleotides.

Authors: Baker YR Thorpe C Chen J et al.

Source: Nature communications [Nat Commun] 2022 Jul 12; Vol. 13 (1), pp. 4036. Date of Electronic Publication: 2022 Jul 12.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

Preclinical Evaluation of ⁸⁹Zr-Df-IAB22M2C PET as an Imaging Biomarker for the Development of the GUCY2C-CD3 Bispecific PF-07062119 as a T Cell Engaging Therapy.

Authors: Maresca KP Chen J Mathur D et al.

Source: Molecular imaging and biology [Mol Imaging Biol] 2021 Dec; Vol. 23 (6), pp. 941-951. Date of Electronic Publication: 2021 Jun 18.

Publication Type: Journal Article

Journal Info: Publisher: Springer Country of Publication: United States NLM ID: 101125610 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1860-2002 (Electronic) Linking ISSN: 15361632 NLM ISO Abbreviation: Mol Imaging Biol Subsets: MEDLINE

2'-Alkynyl spin-labelling is a minimally perturbing tool for DNA structural analysis.

Authors: Hardwick JS Haugland MM El-Sagheer AH et al.

Source: Nucleic acids research [Nucleic Acids Res] 2020 Apr 06; Vol. 48 (6), pp. 2830-2840.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN: 1362-4962 (Electronic) Linking ISSN: 03051048 NLM ISO Abbreviation: Nucleic Acids Res Subsets: MEDLINE

Epigenetic Modifications of Cytosine: Biophysical Properties, Regulation, and Function in Mammalian DNA.

Authors: Hardwick JS Lane AN Brown T

Source: BioEssays : news and reviews in molecular, cellular and developmental biology [Bioessays] 2018 Mar; Vol. 40 (3). Date of Electronic Publication: 2018 Jan 25.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Review

Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 8510851 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-1878 (Electronic) Linking ISSN: 02659247 NLM ISO Abbreviation: Bioessays Subsets: MEDLINE

An accessible pharmacodynamic transcriptional biomarker for notch target engagement.

Authors: Tanis KQ Podtelezhnikov AA Blackman SC et al.

Source: Clinical pharmacology and therapeutics [Clin Pharmacol Ther] 2016 Apr; Vol. 99 (4), pp. 370-80. Date of Electronic Publication: 2016 Feb 17.

Publication Type: Clinical Trial, Phase I; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 0372741 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-6535 (Electronic) Linking ISSN: 00099236 NLM ISO Abbreviation: Clin Pharmacol Ther Subsets: MEDLINE

Phase I trial of vorinostat combined with bortezomib for the treatment of relapsing and/or refractory multiple myeloma.

Authors: Weber DM Graef T Hussein M et al.

Source: Clinical lymphoma, myeloma & leukemia [Clin Lymphoma Myeloma Leuk] 2012 Oct; Vol. 12 (5), pp. 319-24.

Publication Type: Clinical Trial, Phase I; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 101525386 Publication Model: Print Cited Medium: Internet ISSN: 2152-2669 (Electronic) Linking ISSN: 21522669 NLM ISO Abbreviation: Clin Lymphoma Myeloma Leuk Subsets: MEDLINE

Vorinostat combined with bexarotene for treatment of cutaneous T-cell lymphoma: in vitro and phase I clinical evidence supporting augmentation of retinoic acid receptor/retinoid X receptor activation by histone deacetylase inhibition.

Authors: Dummer R Beyer M Hymes K et al.

Source: Leukemia & lymphoma [Leuk Lymphoma] 2012 Aug; Vol. 53 (8), pp. 1501-8. Date of Electronic Publication: 2012 Feb 13.

Publication Type: Clinical Trial, Phase I; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 9007422 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1029-2403 (Electronic) Linking ISSN: 10268022 NLM ISO Abbreviation: Leuk Lymphoma Subsets: MEDLINE

Aprepitant for the prevention of chemotherapy-induced nausea and vomiting associated with a broad range of moderately emetogenic chemotherapies and tumor types: a randomized, double-blind study.

Authors: Rapoport BL Jordan K Boice JA et al.

Source: Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer [Support Care Cancer] 2010 Apr; Vol. 18 (4), pp. 423-31. Date of Electronic Publication: 2009 Jul 01.

Publication Type: Clinical Trial, Phase III; Comparative Study; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Springer International Country of Publication: Germany NLM ID: 9302957 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1433-7339 (Electronic) Linking ISSN: 09414355 NLM ISO Abbreviation: Support Care Cancer Subsets: MEDLINE

Phase I and pharmacokinetic study of vorinostat (suberoylanilide hydroxamic acid) in Japanese patients with solid tumors.

Authors: Fujiwara Y Yamamoto N Yamada Y et al.

Source: Cancer science [Cancer Sci] 2009 Sep; Vol. 100 (9), pp. 1728-34. Date of Electronic Publication: 2009 May 31.

Publication Type: Clinical Trial, Phase I; Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Wiley Publishing on behalf of the Japanese Cancer Association Country of Publication: England NLM ID: 101168776 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1349-7006 (Electronic) Linking ISSN: 13479032 NLM ISO Abbreviation: Cancer Sci Subsets: MEDLINE

Combining CDK4/6 inhibition with taxanes enhances anti-tumor efficacy by sustained impairment of pRB-E2F pathways in squamous cell lung cancer.

Authors: Cao J Zhu Z Wang H et al.

Source: Oncogene [Oncogene] 2019 May; Vol. 38 (21), pp. 4125-4141. Date of Electronic Publication: 2019 Jan 30.

Publication Type: Journal Article

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5594 (Electronic) Linking ISSN: 09509232 NLM ISO Abbreviation: Oncogene Subsets: MEDLINE

Stoichiometry and Dispersity of DNA Nanostructures Using Photobleaching Pair-Correlation Analysis.

Authors: Hariri AA Hamblin GD Hardwick JS et al.

Source: Bioconjugate chemistry [Bioconjug Chem] 2017 Sep 20; Vol. 28 (9), pp. 2340-2349. Date of Electronic Publication: 2017 Aug 22.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9010319 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4812 (Electronic) Linking ISSN: 10431802 NLM ISO Abbreviation: Bioconjug Chem Subsets: MEDLINE

Creating space for relationships.

Authors: Maataoui SL Hardwick JS Lundquist TS

Source: Psychological services [Psychol Serv] 2017 Aug; Vol. 14 (3), pp. 347-351.

Publication Type: Journal Article

Journal Info: Publisher: Educational Publishing Foundation Country of Publication: United States NLM ID: 101214316 Publication Model: Print Cited Medium: Internet ISSN: 1939-148X (Electronic) Linking ISSN: 15411559 NLM ISO Abbreviation: Psychol Serv Subsets: MEDLINE

5-Formylcytosine does not change the global structure of DNA.

Authors: Hardwick JS Ptchelkine D El-Sagheer AH et al.

Source: Nature structural & molecular biology [Nat Struct Mol Biol] 2017 Jun; Vol. 24 (6), pp. 544-552. Date of Electronic Publication: 2017 May 15.

Publication Type: Journal Article

Journal Info: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101186374 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1545-9985 (Electronic) Linking ISSN: 15459985 NLM ISO Abbreviation: Nat Struct Mol Biol Subsets: MEDLINE

Downregulation of MHC-I expression is prevalent but reversible in Merkel cell carcinoma.

Authors: Paulson KG Tegeder A Willmes C et al.

Source: Cancer immunology research [Cancer Immunol Res] 2014 Nov; Vol. 2 (11), pp. 1071-9. Date of Electronic Publication: 2014 Aug 12.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 101614637 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2326-6074 (Electronic) Linking ISSN: 23266066 NLM ISO Abbreviation: Cancer Immunol Res Subsets: MEDLINE

A phase I pharmacokinetic and pharmacodynamic study of dalotuzumab (MK-0646), an anti-insulin-like growth factor-1 receptor monoclonal antibody, in patients with advanced solid tumors.

Authors: Atzori F Tabernero J Cervantes A et al.

Source: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2011 Oct 01; Vol. 17 (19), pp. 6304-12. Date of Electronic Publication: 2011 Aug 02.

Publication Type: Clinical Trial, Phase I; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 9502500 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1557-3265 (Electronic) Linking ISSN: 10780432 NLM ISO Abbreviation: Clin Cancer Res Subsets: MEDLINE

Single-dose fosaprepitant for the prevention of chemotherapy-induced nausea and vomiting associated with cisplatin therapy: randomized, double-blind study protocol--EASE.

Authors: Grunberg S Chua D Maru A et al.

Source: Journal of clinical oncology : official journal of the American Society of Clinical Oncology [J Clin Oncol] 2011 Apr 10; Vol. 29 (11), pp. 1495-501. Date of Electronic Publication: 2011 Mar 07.

Publication Type: Clinical Trial, Phase III; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Society of Clinical Oncology Country of Publication: United States NLM ID: 8309333 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1527-7755 (Electronic) Linking ISSN: 0732183X NLM ISO Abbreviation: J Clin Oncol Subsets: MEDLINE

A 4-gene signature predicts survival of patients with resected adenocarcinoma of the esophagus, junction, and gastric cardia.

Authors: Peters CJ Rees JR Hardwick RH et al.

Corporate Authors: Peters CJ Rees JR Hardwick RH et al.

Source: Gastroenterology [Gastroenterology] 2010 Dec; Vol. 139 (6), pp. 1995-2004.e15. Date of Electronic Publication: 2010 Jun 02.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Validation Study

Journal Info: Publisher: W.B. Saunders Country of Publication: United States NLM ID: 0374630 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1528-0012 (Electronic) Linking ISSN: 00165085 NLM ISO Abbreviation: Gastroenterology Subsets: MEDLINE

Stromal genes discriminate preinvasive from invasive disease, predict outcome, and highlight inflammatory pathways in digestive cancers.

Authors: Saadi A Shannon NB Lao-Sirieix P et al.

Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2010 Feb 02; Vol. 107 (5), pp. 2177-82. Date of Electronic Publication: 2010 Jan 13.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

Development of vorinostat: current applications and future perspectives for cancer therapy.

Authors: Richon VM Garcia-Vargas J Hardwick JS

Source: Cancer letters [Cancer Lett] 2009 Aug 08; Vol. 280 (2), pp. 201-10. Date of Electronic Publication: 2009 Jan 31.

Publication Type: Journal Article; Review

Journal Info: Publisher: Elsevier Science Ireland Country of Publication: Ireland NLM ID: 7600053 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7980 (Electronic) Linking ISSN: 03043835 NLM ISO Abbreviation: Cancer Lett Subsets: MEDLINE