Search Results - "Harikumar KB"

Uttroside B, a US FDA-designated 'Orphan Drug', mitigates the development of hepatocellular carcinoma and its pulmonary metastasis via EGFR/ERK-mediated inhibition of SREBP-1 and STAT-3.

Authors: Keerthana CK Rayginia TP Kalimuthu K et al.

Source: Cell death discovery [Cell Death Discov] 2026 Apr 16; Vol. 12 (1). Date of Electronic Publication: 2026 Apr 16.

Publication Type: Journal Article

Journal Info: Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 101665035 Publication Model: Electronic Cited Medium: Print ISSN: 2058-7716 (Print) Linking ISSN: 20587716 NLM ISO Abbreviation: Cell Death Discov Subsets: PubMed not MEDLINE

Targeting Leishmania donovani Sphingosine Kinase 1 using PF-543 enhances immune response and limits parasite load.

Authors: Madan, Evanka Bansal, Ruby Singhal, Jhalak et al.

Source: PLoS Neglected Tropical Diseases. 3/20/2026, Vol. 20 Issue 3, p1-33. 33p.

Review on the synthetic pathway and pharmacological significance of benzothiazole derivatives in medicinal chemistry.

Authors: Talukdar, Saurav Kr. Kalita, Sanjit Thakuria, Nilanjana et al.

Source: Discover Chemistry. 6/5/2026, Vol. 3 Issue 1, p1-34. 34p.

Orphan drug uttroside B impedes MASH progression and HCC development in experimental models.

Authors: Rayginia TP Keerthana CK Aiswarya SU et al.

Source: JHEP reports : innovation in hepatology [JHEP Rep] 2025 Oct 10; Vol. 8 (2), pp. 101626. Date of Electronic Publication: 2025 Oct 10 (Print Publication: 2026).

Publication Type: Journal Article

Journal Info: Publisher: Elsevier B.V Country of Publication: Netherlands NLM ID: 101761237 Publication Model: eCollection Cited Medium: Internet ISSN: 2589-5559 (Electronic) Linking ISSN: 25895559 NLM ISO Abbreviation: JHEP Rep Subsets: In Process

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Smoking and bladder cancer: insights into pathogenesis and public health implications from a bibliometric analysis (1999–2023).

Authors: Wang, Yang Zhou, Hancheng Tang, Zhicheng et al.

Source: Substance Abuse Treatment, Prevention & Policy. 6/14/2025, Vol. 20 Issue 1, p1-13. 13p.

Navigating the complexities of epigenetic dysregulation in breast cancer and its implication in therapeutic interventions: a comprehensive overview.

Authors: Ravindran S Vini R Rajavelu A et al.

Source: Molecular and cellular biochemistry [Mol Cell Biochem] 2026 Jan; Vol. 481 (1), pp. 171-186. Date of Electronic Publication: 2025 Oct 23.

Publication Type: Journal Article; Review

Journal Info: Publisher: Springer Country of Publication: Netherlands NLM ID: 0364456 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-4919 (Electronic) Linking ISSN: 03008177 NLM ISO Abbreviation: Mol Cell Biochem Subsets: MEDLINE

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Curcumin-based biocompatible nanocarriers: a contemporary perspective in functional foods and biomedical applications.

Authors: Alshammari, Eida M.¹, eida.alshammari@uoh.edu.sa

Source: Discover Nano; 12/8/2025, Vol. 20 Issue 1, p1-33, 33p

Synthesis and evaluation of carmofur analogs as antiproliferative agents, inhibitors to the main protease (M^pro) of SARS-CoV-2, and membrane rupture-inducing agents.

Authors: Gu, Tiffany Lu, Amber Wang, Xina et al.

Source: Discover Chemistry. Dec2025, Vol. 2 Issue 1, p1-15. 15p.

Network pharmacology study to identify molecular pathways involved in the anti-diabetic activity of

Authors: Dubey, Vishal Kansagra, Jignesh Kamani, Bhargav et al.

Source: Networks & Heterogeneous Media; 2025, Vol. 20 Issue 3, p1-17, 17p

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Cytotoxic and Antioxidant Effects of Curcumin Nanoparticles on Hepatic Cell Lines Exposed to Acetaminophen-Induced Toxicity: An In Vitro Experimental Study.

Authors: Alzaidy, Asaad H. Ganduh, Safaa H. Hussien, Murtadha Saleh

Source: Journal of Nanostructures. Summer2026, Vol. 16 Issue 3, p3153-3161. 9p.

Curcumin-Mediated Downregulation of Gene Expression Inhibits Enterococcus faecalis Biofilm Formation.

Authors: Alisaac, Ali¹ (AUTHOR) aalisaac@bu.edu.sa

Source: Arabian Journal for Science & Engineering (Springer Science & Business Media B.V. ). Jun2026, Vol. 51 Issue 11, p13741-13752. 12p.

Dysbiosis of gut microbiota in children with functional constipation and damp-heat constitution: a cross-sectional multi-omics analysis.

Authors: Zhao, Haihong Lu, Xiuxia Ye, Yanbin et al.

Source: Scientific Reports. 11/26/2025, Vol. 15 Issue 1, p1-16. 16p.

Mass spectrometry-based untargeted metabolomics study of polycystic ovary syndrome.

Authors: Özer, Ömer Faruk İbrahimoğlu, Ayşe Zeynep Gül, Ayşe Zehra et al.

Source: Journal of Ovarian Research. 11/12/2025, Vol. 18 Issue 1, p1-12. 12p.

Overlapping Syndrome of Myocarditis, Myositis, Transaminitis, and Myasthenia Gravis in a Patient with Hepatocellular Carcinoma after Treatment with Immune Checkpoint Inhibitors: A Case Report and Literature Review.

Authors: Kalifu, Baheti Meng, Yuan Aishanjiang, Kedeerya et al.

Source: Case Reports in Gastroenterology. 2025, Vol. 19 Issue 1, p611-620. 10p.

N7-methylguanosine (m7G) modification in breast cancer: clinical significances and molecular mechanisms.

Authors: Yang, Tianyao Chen, Chunyan Wang, Fangfang et al.

Source: Cancer Cell International. 8/12/2025, Vol. 25 Issue 1, p1-14. 14p.

Targeting sphingosine-1-phosphate receptor 1 alleviates neuropathic pain associated with pancreatic ductal adenocarcinoma in mice and inhibits tumor progression.

Authors: Cai, Shen-quan Zhang, Yi-xuan Wang, Chun et al.

Source: Molecular Pain. 8/13/2025, Vol. 21, p1-18. 18p.

Resveratrol attenuates hepatic oxidative stress and preserves gut mucosal integrity in high-fat diet-fed rats by modulating antioxidant and anti-inflammatory pathways.

Authors: Yasmin, Tahmina Menon, Sreelakshmi N. Pandey, Ajay et al.

Source: Scientific Reports. 7/11/2025, Vol. 15 Issue 1, p1-20. 20p.