Search Results - "Heck CJS"

Biotransformation research advances-2025 year in review.

Authors: Cheruzel L Argikar UA Brunetti P et al.

Source: Drug metabolism reviews [Drug Metab Rev] 2026 May 25, pp. 1-58. Date of Electronic Publication: 2026 May 25.

Publication Type: Journal Article; Review

Journal Info: Publisher: Informa Healthcare Country of Publication: England NLM ID: 0322067 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-9883 (Electronic) Linking ISSN: 03602532 NLM ISO Abbreviation: Drug Metab Rev Subsets: MEDLINE

Bioactivation and reactivity research advances - 2023 year in review.

Authors: Wang S Argikar UA Chatzopoulou M et al.

Source: Drug metabolism reviews [Drug Metab Rev] 2024 Aug; Vol. 56 (3), pp. 247-284. Date of Electronic Publication: 2024 Jul 17.

Publication Type: Journal Article; Review

Journal Info: Publisher: Informa Healthcare Country of Publication: England NLM ID: 0322067 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-9883 (Electronic) Linking ISSN: 03602532 NLM ISO Abbreviation: Drug Metab Rev Subsets: MEDLINE

Studies addressing potential bioactivation and genotoxicity liabilities of the N-nitroso derivative of the antidepressant paroxetine.

Authors: Heck CJS Eng H Cheung JR et al.

Source: Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 2025 Oct; Vol. 55 (10), pp. 737-752. Date of Electronic Publication: 2025 Nov 18.

Publication Type: Journal Article

Journal Info: Publisher: Informa Healthcare Country of Publication: England NLM ID: 1306665 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1366-5928 (Electronic) Linking ISSN: 00498254 NLM ISO Abbreviation: Xenobiotica Subsets: MEDLINE

Biotransformation research advances - 2022 year in review.

Authors: Khojasteh SC Argikar UA Cheruzel L et al.

Source: Drug metabolism reviews [Drug Metab Rev] 2023 Nov; Vol. 55 (4), pp. 301-342. Date of Electronic Publication: 2023 Oct 28.

Publication Type: Journal Article; Review

Journal Info: Publisher: Informa Healthcare Country of Publication: England NLM ID: 0322067 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-9883 (Electronic) Linking ISSN: 03602532 NLM ISO Abbreviation: Drug Metab Rev Subsets: MEDLINE

Bioactivation and reactivity research advances - 2022 year in review‡.

Authors: Wang S Argikar UA Cheruzel L et al.

Source: Drug metabolism reviews [Drug Metab Rev] 2023 Nov; Vol. 55 (4), pp. 267-300. Date of Electronic Publication: 2023 Aug 22.

Publication Type: Journal Article; Review

Journal Info: Publisher: Informa Healthcare Country of Publication: England NLM ID: 0322067 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-9883 (Electronic) Linking ISSN: 03602532 NLM ISO Abbreviation: Drug Metab Rev Subsets: MEDLINE

Applications of contemporary tools to measure plasma protein binding of targeted protein degraders.

Authors: Niosi M Zhang S Burchett W et al.

Source: Drug metabolism and disposition: the biological fate of chemicals [Drug Metab Dispos] 2025 May; Vol. 53 (5), pp. 100066. Date of Electronic Publication: 2025 Mar 19.

Publication Type: Journal Article

Journal Info: Publisher: American Society for Pharmacology and Experimental Therapeutics, etc.] Country of Publication: Netherlands NLM ID: 9421550 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-009X (Electronic) Linking ISSN: 00909556 NLM ISO Abbreviation: Drug Metab Dispos Subsets: MEDLINE

Bioactivation and reactivity research advances - 2021 year in review.

Authors: Jackson KD Argikar UA Cho S et al.

Source: Drug metabolism reviews [Drug Metab Rev] 2022 Aug; Vol. 54 (3), pp. 246-281. Date of Electronic Publication: 2022 Aug 05.

Publication Type: Journal Article; Review; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

Journal Info: Publisher: Informa Healthcare Country of Publication: England NLM ID: 0322067 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-9883 (Electronic) Linking ISSN: 03602532 NLM ISO Abbreviation: Drug Metab Rev Subsets: MEDLINE

Biotransformation novel advances - 2021 year in review.

Authors: Khojasteh SC Argikar UA Cho S et al.

Source: Drug metabolism reviews [Drug Metab Rev] 2022 Aug; Vol. 54 (3), pp. 207-245. Date of Electronic Publication: 2022 Aug 30.

Publication Type: Journal Article; Review

Journal Info: Publisher: Informa Healthcare Country of Publication: England NLM ID: 0322067 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-9883 (Electronic) Linking ISSN: 03602532 NLM ISO Abbreviation: Drug Metab Rev Subsets: MEDLINE

Novel advances in biotransformation and bioactivation research - 2020 year in review.

Authors: Khojasteh SC Argikar UA Driscoll JP et al.

Source: Drug metabolism reviews [Drug Metab Rev] 2021 Aug; Vol. 53 (3), pp. 384-433. Date of Electronic Publication: 2021 Jun 24.

Publication Type: Journal Article; Research Support, N.I.H., Extramural

Journal Info: Publisher: Informa Healthcare Country of Publication: England NLM ID: 0322067 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-9883 (Electronic) Linking ISSN: 03602532 NLM ISO Abbreviation: Drug Metab Rev Subsets: MEDLINE

Probing Ligand Structure-Activity Relationships in Pregnane X Receptor (PXR): Efavirenz and 8-Hydroxyefavirenz Exhibit Divergence in Activation.

Authors: Narayanan B Lade JM Heck CJS et al.

Source: ChemMedChem [ChemMedChem] 2018 Apr 06; Vol. 13 (7), pp. 736-747. Date of Electronic Publication: 2018 Mar 02.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

Journal Info: Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 101259013 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1860-7187 (Electronic) Linking ISSN: 18607179 NLM ISO Abbreviation: ChemMedChem Subsets: MEDLINE

Future of Biotransformation Science in the Pharmaceutical Industry.

Authors: Kramlinger VM Dalvie D Heck CJS et al.

Source: Drug metabolism and disposition: the biological fate of chemicals [Drug Metab Dispos] 2022 Mar; Vol. 50 (3), pp. 258-267. Date of Electronic Publication: 2021 Dec 17.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 9421550 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-009X (Electronic) Linking ISSN: 00909556 NLM ISO Abbreviation: Drug Metab Dispos Subsets: MEDLINE

Neurotoxicity with high-dose disulfiram and vorinostat used for HIV latency reversal.

Authors: McMahon JH Evans VA Lau JSY et al.

Source: AIDS (London, England) [AIDS] 2022 Jan 01; Vol. 36 (1), pp. 75-82.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Lippincott Williams & Wilkins Country of Publication: England NLM ID: 8710219 Publication Model: Print Cited Medium: Internet ISSN: 1473-5571 (Electronic) Linking ISSN: 02699370 NLM ISO Abbreviation: AIDS Subsets: MEDLINE

Twelfth-Position Deuteration of Nevirapine Reduces 12-Hydroxy-Nevirapine Formation and Nevirapine-Induced Hepatocyte Death.

Authors: Heck CJS Seneviratne HK Bumpus NN

Source: Journal of medicinal chemistry [J Med Chem] 2020 Jun 25; Vol. 63 (12), pp. 6561-6574. Date of Electronic Publication: 2020 Feb 27.

Publication Type: Journal Article

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

Spatial Distribution Profiles of Emtricitabine, Tenofovir, Efavirenz, and Rilpivirine in Murine Tissues Following In Vivo Dosing Correlate with Their Safety Profiles in Humans.

Authors: Seneviratne HK Hamlin AN Heck CJS et al.

Source: ACS pharmacology & translational science [ACS Pharmacol Transl Sci] 2020 Apr 23; Vol. 3 (4), pp. 655-665. Date of Electronic Publication: 2020 Apr 23 (Print Publication: 2020).

Publication Type: Journal Article

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101721411 Publication Model: eCollection Cited Medium: Internet ISSN: 2575-9108 (Electronic) Linking ISSN: 25759108 NLM ISO Abbreviation: ACS Pharmacol Transl Sci Subsets: PubMed not MEDLINE

Efavirenz and Efavirenz-like Compounds Activate Human, Murine, and Macaque Hepatic IRE1α-XBP1.

Authors: Heck CJS Hamlin AN Bumpus NN

Source: Molecular pharmacology [Mol Pharmacol] 2019 Feb; Vol. 95 (2), pp. 183-195. Date of Electronic Publication: 2018 Nov 15.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.

Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 0035623 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-0111 (Electronic) Linking ISSN: 0026895X NLM ISO Abbreviation: Mol Pharmacol Subsets: MEDLINE