Search Results - "Heck CJS"

Biotransformation research advances – 2022 year in review.

Authors: Khojasteh, S. Cyrus Argikar, Upendra A. Cheruzel, Lionel et al.

Source: Drug Metabolism Reviews. Nov2023, Vol. 55 Issue 4, p301-342. 42p.

Metabolism of new drug modalities research advances – 2023 year in review.

Authors: Ma, Bin Argikar, Upendra A Cheruzel, Lionel et al.

Source: Drug Metabolism Reviews. Aug2024, Vol. 56 Issue 3, p223-246. 24p.

Biotransformation research advances – 2023 year in review.

Authors: Khojasteh, S. Cyrus Argikar, Upendra A. Chatzopoulou, Maria et al.

Source: Drug Metabolism Reviews. Aug2024, Vol. 56 Issue 3, p190-222. 33p.

Biotransformation novel advances – 2021 year in review.

Authors: Khojasteh, S. Cyrus Argikar, Upendra A. Cho, Sungjoon et al.

Source: Drug Metabolism Reviews. Aug2022, Vol. 54 Issue 3, p207-245. 39p.

Bioactivation and reactivity research advances – 2021 year in review.

Authors: Jackson, Klarissa D. Argikar, Upendra A. Cho, Sungjoon et al.

Source: Drug Metabolism Reviews. Aug2022, Vol. 54 Issue 3, p246-281. 36p.

Applications of contemporary tools to measure plasma protein binding of targeted protein degraders.

Authors: Niosi M Zhang S Burchett W et al.

Source: Drug metabolism and disposition: the biological fate of chemicals [Drug Metab Dispos] 2025 May; Vol. 53 (5), pp. 100066. Date of Electronic Publication: 2025 Mar 19.

Publication Type: Journal Article

Journal Info: Publisher: American Society for Pharmacology and Experimental Therapeutics, etc.] Country of Publication: Netherlands NLM ID: 9421550 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-009X (Electronic) Linking ISSN: 00909556 NLM ISO Abbreviation: Drug Metab Dispos Subsets: MEDLINE

Bioactivation and reactivity research advances - 2022 year in review‡.

Authors: Wang S Argikar UA Cheruzel L et al.

Source: Drug metabolism reviews [Drug Metab Rev] 2023 Nov; Vol. 55 (4), pp. 267-300. Date of Electronic Publication: 2023 Aug 22.

Publication Type: Journal Article; Review

Journal Info: Publisher: Informa Healthcare Country of Publication: England NLM ID: 0322067 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-9883 (Electronic) Linking ISSN: 03602532 NLM ISO Abbreviation: Drug Metab Rev Subsets: MEDLINE

Trends analysis and future study of the pharmaceutical industry field: a scoping review.

Authors: Bashirynejad, Manuchehr Soleymani, Fatemeh Nikfar, Shekoufeh et al.

Source: DARU: Journal of Pharmaceutical Sciences. Jun2025, Vol. 33 Issue 1, p1-15. 15p.

Efavirenz-Induced Hepatic Changes in the Fetus of Swiss Albino Mice.

Authors: Mishra, Anand Sharma, Akansha Yadav, Archna et al.

Source: National Academy Science Letters. Oct2024, Vol. 47 Issue 5, p489-493. 5p.

Mass spectrometry imaging‐based multi‐omics approaches to understand drug metabolism and disposition.

Authors: Phulara, Nav Raj Seneviratne, Herana Kamal

Source: Journal of Mass Spectrometry. Jul2024, Vol. 59 Issue 7, p1-5. 5p.

Novel advances in biotransformation and bioactivation research - 2020 year in review.

Authors: Khojasteh SC Argikar UA Driscoll JP et al.

Source: Drug metabolism reviews [Drug Metab Rev] 2021 Aug; Vol. 53 (3), pp. 384-433. Date of Electronic Publication: 2021 Jun 24.

Publication Type: Journal Article; Research Support, N.I.H., Extramural

Journal Info: Publisher: Informa Healthcare Country of Publication: England NLM ID: 0322067 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-9883 (Electronic) Linking ISSN: 03602532 NLM ISO Abbreviation: Drug Metab Rev Subsets: MEDLINE

Future of Biotransformation Science in the Pharmaceutical Industry.

Authors: Kramlinger VM Dalvie D Heck CJS et al.

Source: Drug metabolism and disposition: the biological fate of chemicals [Drug Metab Dispos] 2022 Mar; Vol. 50 (3), pp. 258-267. Date of Electronic Publication: 2021 Dec 17.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 9421550 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-009X (Electronic) Linking ISSN: 00909556 NLM ISO Abbreviation: Drug Metab Dispos Subsets: MEDLINE

Utilizing mechanistic organic chemistry training to study drug metabolism in preclinical drug discovery/development.

Authors: Dalvie, Deepak Kalgutkar, Amit S.

Source: Medicinal Chemistry Research. Sep2023, Vol. 32 Issue 9, p1922-1932. 11p.

Fundamental aspects of long-acting tenofovir alafenamide delivery from subdermal implants for HIV prophylaxis.

Authors: Gunawardana, Manjula Remedios-Chan, Mariana Sanchez, Debbie et al.

Source: Scientific Reports. 5/17/2022, Vol. 12 Issue 1, p1-25. 25p.

Spatial Distribution Profiles of Emtricitabine, Tenofovir, Efavirenz, and Rilpivirine in Murine Tissues Following In Vivo Dosing Correlate with Their Safety Profiles in Humans.

Authors: Seneviratne HK Hamlin AN Heck CJS et al.

Source: ACS pharmacology & translational science [ACS Pharmacol Transl Sci] 2020 Apr 23; Vol. 3 (4), pp. 655-665. Date of Electronic Publication: 2020 Apr 23 (Print Publication: 2020).

Publication Type: Journal Article

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101721411 Publication Model: eCollection Cited Medium: Internet ISSN: 2575-9108 (Electronic) Linking ISSN: 25759108 NLM ISO Abbreviation: ACS Pharmacol Transl Sci Subsets: PubMed not MEDLINE

Cocaine regulates antiretroviral therapy CNS access through pregnane-x receptor-mediated drug transporter and metabolizing enzyme modulation at the blood brain barrier.

Authors: Colón Ortiz, Rodnie Knerler, Stephen Fridman, Lisa B. et al.

Source: Fluids & Barriers of the CNS. 1/10/2024, Vol. 21 Issue 1, p1-27. 27p.

The past decade of Genentech experience in elucidation of novel reaction mechanisms in drug metabolism.

Authors: Khojasteh, Cyrus Sodhi, Jasleen K. Halladay, Jason et al.

Source: Medicinal Chemistry Research. Sep2023, Vol. 32 Issue 9, p2016-2033. 18p.

Advances in mass spectrometry imaging for toxicological analysis and safety evaluation of pharmaceuticals.

Authors: Chen, Yilin Xie, Yanqiao Li, Linnan et al.

Source: Mass Spectrometry Reviews. Sep2023, Vol. 42 Issue 5, p2207-2233. 27p.

A commentary on the use of pharmacoenhancers in the pharmaceutical industry and the implication for DMPK drug discovery strategies.

Authors: Martins, Vanessa Fazal, Lynsey Oganesian, Aram et al.

Source: Xenobiotica. Aug2022, Vol. 52 Issue 8, p786-796. 11p.

Humanized Mice for Infectious and Neurodegenerative disorders.

Authors: Dash, Prasanta K. Gorantla, Santhi Poluektova, Larisa et al.

Source: Retrovirology. 6/5/2021, Vol. 18 Issue 1, p1-17. 17p.