Search Results - "Howarth CL"

Targeted degradation of MDM2 overcomes feedback regulation of p53 signaling in Merkel cell carcinoma models.

Authors: Ananthapadmanabhan V Bruno S Vonk L et al.

Source: The Journal of clinical investigation [J Clin Invest] 2026 Jul 01; Vol. 136 (13). Date of Electronic Publication: 2026 Jul 01 (Print Publication: 2026).

Publication Type: Journal Article

Journal Info: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model: eCollection Cited Medium: Internet ISSN: 1558-8238 (Electronic) Linking ISSN: 00219738 NLM ISO Abbreviation: J Clin Invest Subsets: MEDLINE

CDK2 heterobifunctional degraders co-degrade CDK2 and cyclin E resulting in efficacy in CCNE1-amplified and overexpressed cancers.

Authors: Kwiatkowski N Liang T Sha Z et al.

Source: Cell chemical biology [Cell Chem Biol] 2025 Apr 17; Vol. 32 (4), pp. 556-569.e24.

Publication Type: Journal Article

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101676030 Publication Model: Print Cited Medium: Internet ISSN: 2451-9448 (Electronic) Linking ISSN: 24519448 NLM ISO Abbreviation: Cell Chem Biol Subsets: MEDLINE

Tumor microtubes connect pancreatic cancer cells in an Arp2/3 complex-dependent manner.

Authors: Latario CJ Schoenfeld LW Howarth CL et al.

Source: Molecular biology of the cell [Mol Biol Cell] 2020 Jun 01; Vol. 31 (12), pp. 1259-1272. Date of Electronic Publication: 2020 Apr 08.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Society for Cell Biology Country of Publication: United States NLM ID: 9201390 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1939-4586 (Electronic) Linking ISSN: 10591524 NLM ISO Abbreviation: Mol Biol Cell Subsets: MEDLINE