Search Results - "Howson JM"

Genetic analysis of adult-onset autoimmune diabetes.

Authors: Howson JM Rosinger S Smyth DJ et al.

Source: Diabetes. Oct2011, Vol. 60 Issue 10, p2645-2653. 9p.

PTPN22 Trp620 explains the association of chromosome 1p13 with type 1 diabetes and shows a statistical interaction with HLA class II genotypes.

Authors: Smyth DJ Cooper JD Howson JM et al.

Source: Diabetes. Jun2008, Vol. 57 Issue 6, p1730-1737. 8p.

URL: 32803197

Genetic architecture of sleep in a genome wide association study of device measured sleep traits.

Authors: Portas L Yuan H Cai L et al.

Source: Nature communications [Nat Commun] 2026 Apr 01; Vol. 17 (1). Date of Electronic Publication: 2026 Apr 01.

Publication Type: Journal Article

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

Deciphering tissue-specific protein regulation for insights into cardiometabolic disease.

Authors: Hartley AE Sukhavasi K Hu S et al.

Source: Molecular metabolism [Mol Metab] 2026 Feb; Vol. 104, pp. 102314. Date of Electronic Publication: 2025 Dec 26.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier GmbH Country of Publication: Germany NLM ID: 101605730 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2212-8778 (Electronic) Linking ISSN: 22128778 NLM ISO Abbreviation: Mol Metab Subsets: MEDLINE

Lipoprotein(a) concentrations and secondary outcomes following first-time acute coronary syndrome: The Multi-Ethnic New Zealand Study of Acute Coronary Syndromes (MENZACS).

Authors: Legget ME Earle NJ Poppe KK et al.

Source: Atherosclerosis [Atherosclerosis] 2025 Nov; Vol. 410, pp. 120516. Date of Electronic Publication: 2025 Sep 10.

Publication Type: Journal Article; Multicenter Study

Journal Info: Publisher: Elsevier Country of Publication: Ireland NLM ID: 0242543 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-1484 (Electronic) Linking ISSN: 00219150 NLM ISO Abbreviation: Atherosclerosis Subsets: MEDLINE

De novo variants in the non-coding spliceosomal snRNA gene RNU4-2 are a frequent cause of syndromic neurodevelopmental disorders.

Authors: Chen Y Dawes R Kim HC et al.

Source: MedRxiv : the preprint server for health sciences [medRxiv] 2024 Apr 09. Date of Electronic Publication: 2024 Apr 09.

Publication Type: Preprint; Journal Article

Journal Info: Country of Publication: United States NLM ID: 101767986 Publication Model: Electronic Cited Medium: Internet NLM ISO Abbreviation: medRxiv Subsets: PubMed not MEDLINE

Formalising recall by genotype as an efficient approach to detailed phenotyping and causal inference.

Authors: Corbin LJ Tan VY Hughes DA et al.

Source: Nature communications [Nat Commun] 2018 Feb 19; Vol. 9 (1), pp. 711. Date of Electronic Publication: 2018 Feb 19.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Review

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

Genetic invalidation of Lp-PLA2 as a therapeutic target: Large-scale study of five functional Lp-PLA2-lowering alleles.

Authors: Gregson JM Freitag DF Surendran P et al.

Corporate Authors: Gregson JM Freitag DF Surendran P et al.

Source: European journal of preventive cardiology [Eur J Prev Cardiol] 2017 Mar; Vol. 24 (5), pp. 492-504. Date of Electronic Publication: 2016 Dec 08.

Publication Type: Journal Article; Systematic Review

Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 101564430 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2047-4881 (Electronic) Linking ISSN: 20474873 NLM ISO Abbreviation: Eur J Prev Cardiol Subsets: MEDLINE

A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease.

Authors: Scott RA Freitag DF Li L et al.

Corporate Authors: Scott RA Freitag DF Li L et al.

Source: Science translational medicine [Sci Transl Med] 2016 Jun 01; Vol. 8 (341), pp. 341ra76.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE

Rare variant in scavenger receptor BI raises HDL cholesterol and increases risk of coronary heart disease.

Authors: Zanoni P Khetarpal SA Larach DB et al.

Corporate Authors: Zanoni P Khetarpal SA Larach DB et al.

Source: Science (New York, N.Y.) [Science] 2016 Mar 11; Vol. 351 (6278), pp. 1166-71.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE

Additive and interaction effects at three amino acid positions in HLA-DQ and HLA-DR molecules drive type 1 diabetes risk.

Authors: Hu X Deutsch AJ Lenz TL et al.

Source: Nature genetics [Nat Genet] 2015 Aug; Vol. 47 (8), pp. 898-905. Date of Electronic Publication: 2015 Jul 13.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Nature Pub. Co Country of Publication: United States NLM ID: 9216904 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-1718 (Electronic) Linking ISSN: 10614036 NLM ISO Abbreviation: Nat Genet Subsets: MEDLINE

The Bangladesh Risk of Acute Vascular Events (BRAVE) Study: objectives and design.

Authors: Chowdhury R Alam DS Fakir II et al.

Corporate Authors: Chowdhury R Alam DS Fakir II et al.

Source: European journal of epidemiology [Eur J Epidemiol] 2015 Jul; Vol. 30 (7), pp. 577-87. Date of Electronic Publication: 2015 May 01.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Kluwer Academic Publishers Country of Publication: Netherlands NLM ID: 8508062 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-7284 (Electronic) Linking ISSN: 03932990 NLM ISO Abbreviation: Eur J Epidemiol Subsets: MEDLINE

Detection and correction of artefacts in estimation of rare copy number variants and analysis of rare deletions in type 1 diabetes.

Authors: Cooper NJ Shtir CJ Smyth DJ et al.

Source: Human molecular genetics [Hum Mol Genet] 2015 Mar 15; Vol. 24 (6), pp. 1774-90. Date of Electronic Publication: 2014 Nov 25.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: IRL Press at Oxford University Press Country of Publication: England NLM ID: 9208958 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1460-2083 (Electronic) Linking ISSN: 09646906 NLM ISO Abbreviation: Hum Mol Genet Subsets: MEDLINE

A hybrid qPCR/SNP array approach allows cost efficient assessment of KIR gene copy numbers in large samples.

Authors: Pontikos N Smyth DJ Schuilenburg H et al.

Source: BMC genomics [BMC Genomics] 2014 Apr 11; Vol. 15, pp. 274. Date of Electronic Publication: 2014 Apr 11.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 100965258 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2164 (Electronic) Linking ISSN: 14712164 NLM ISO Abbreviation: BMC Genomics Subsets: MEDLINE

Plasma concentrations of soluble IL-2 receptor α (CD25) are increased in type 1 diabetes and associated with reduced C-peptide levels in young patients.

Authors: Downes K Marcovecchio ML Clarke P et al.

Source: Diabetologia [Diabetologia] 2014 Feb; Vol. 57 (2), pp. 366-72. Date of Electronic Publication: 2013 Nov 22.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0006777 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0428 (Electronic) Linking ISSN: 0012186X NLM ISO Abbreviation: Diabetologia Subsets: MEDLINE

HLA class II gene associations in African American type 1 diabetes reveal a protective HLA-DRB1*03 haplotype.

Authors: Howson JM Roy MS Zeitels L et al.

Source: Diabetic medicine : a journal of the British Diabetic Association [Diabet Med] 2013 Jun; Vol. 30 (6), pp. 710-6. Date of Electronic Publication: 2013 Mar 21.

Publication Type: Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Blackwell Science Country of Publication: England NLM ID: 8500858 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1464-5491 (Electronic) Linking ISSN: 07423071 NLM ISO Abbreviation: Diabet Med Subsets: MEDLINE

Functional IL6R 358Ala allele impairs classical IL-6 receptor signaling and influences risk of diverse inflammatory diseases.

Authors: Ferreira RC Freitag DF Cutler AJ et al.

Source: PLoS genetics [PLoS Genet] 2013 Apr; Vol. 9 (4), pp. e1003444. Date of Electronic Publication: 2013 Apr 04.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101239074 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1553-7404 (Electronic) Linking ISSN: 15537390 NLM ISO Abbreviation: PLoS Genet Subsets: MEDLINE

Bayesian refinement of association signals for 14 loci in 3 common diseases.

Authors: Maller JB McVean G Byrnes J et al.

Corporate Authors: Maller JB McVean G Byrnes J et al.

Source: Nature genetics [Nat Genet] 2012 Dec; Vol. 44 (12), pp. 1294-301. Date of Electronic Publication: 2012 Oct 28.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Nature Pub. Co Country of Publication: United States NLM ID: 9216904 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-1718 (Electronic) Linking ISSN: 10614036 NLM ISO Abbreviation: Nat Genet Subsets: MEDLINE

Evidence of gene-gene interaction and age-at-diagnosis effects in type 1 diabetes.

Authors: Howson JM Cooper JD Smyth DJ et al.

Corporate Authors: Howson JM Cooper JD Smyth DJ et al.

Source: Diabetes [Diabetes] 2012 Nov; Vol. 61 (11), pp. 3012-7. Date of Electronic Publication: 2012 Aug 13.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Diabetes Association Country of Publication: United States NLM ID: 0372763 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1939-327X (Electronic) Linking ISSN: 00121797 NLM ISO Abbreviation: Diabetes Subsets: MEDLINE

Genetic association of zinc transporter 8 (ZnT8) autoantibodies in type 1 diabetes cases.

Authors: Howson JM Krause S Stevens H et al.

Source: Diabetologia [Diabetologia] 2012 Jul; Vol. 55 (7), pp. 1978-84. Date of Electronic Publication: 2012 Apr 12.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0006777 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0428 (Electronic) Linking ISSN: 0012186X NLM ISO Abbreviation: Diabetologia Subsets: MEDLINE