Search Results - "Hruby VJ"

Spinal or systemic TY005, a peptidic opioid agonist/neurokinin 1 antagonist, attenuates pain with reduced tolerance.

Authors: Largent-Milnes, TM Yamamoto, T Nair, P et al.

Source: British Journal of Pharmacology. Nov2010, Vol. 161 Issue 5, p986-1001. 16p.

Design, Structure-Activity Relationships, and Computational Modeling Studies of a Series of α-Helix Biased, Ultra-Short Glucagon-like Peptide-1 Receptor Agonists.

Authors: Sawyer JR Audie JA Swanson J et al.

Source: Molecules (Basel, Switzerland) [Molecules] 2024 Dec 24; Vol. 30 (1). Date of Electronic Publication: 2024 Dec 24.

Publication Type: Journal Article

Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049 (Electronic) Linking ISSN: 14203049 NLM ISO Abbreviation: Molecules Subsets: MEDLINE

MC4R biased signalling and the conformational basis of biological function selections.

Authors: Liu Z Hruby VJ

Source: Journal of cellular and molecular medicine [J Cell Mol Med] 2022 Aug; Vol. 26 (15), pp. 4125-4136. Date of Electronic Publication: 2022 Jul 11.

Publication Type: Journal Article; Review

Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101083777 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1582-4934 (Electronic) Linking ISSN: 15821838 NLM ISO Abbreviation: J Cell Mol Med Subsets: MEDLINE

Aged Brains Express Less Melanocortin Receptors, Which Correlates with Age-Related Decline of Cognitive Functions.

Authors: Zhou Y Chawla MK Rios-Monterrosa JL et al.

Source: Molecules (Basel, Switzerland) [Molecules] 2021 Oct 16; Vol. 26 (20). Date of Electronic Publication: 2021 Oct 16.

Publication Type: Journal Article

Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049 (Electronic) Linking ISSN: 14203049 NLM ISO Abbreviation: Molecules Subsets: MEDLINE

Multifunctional Enkephalin Analogs with a New Biological Profile: MOR/DOR Agonism and KOR Antagonism.

Authors: Lee YS Remesic M Ramos-Colon C et al.

Source: Biomedicines [Biomedicines] 2021 May 31; Vol. 9 (6). Date of Electronic Publication: 2021 May 31.

Publication Type: Journal Article

Journal Info: Publisher: MDPI AG Country of Publication: Switzerland NLM ID: 101691304 Publication Model: Electronic Cited Medium: Print ISSN: 2227-9059 (Print) Linking ISSN: 22279059 NLM ISO Abbreviation: Biomedicines Subsets: PubMed not MEDLINE

Development of N-Acetylated Dipalmitoyl-S-Glyceryl Cysteine Analogs as Efficient TLR2/TLR6 Agonists.

Authors: Zhou Y Banday AH Hruby VJ et al.

Source: Molecules (Basel, Switzerland) [Molecules] 2019 Sep 27; Vol. 24 (19). Date of Electronic Publication: 2019 Sep 27.

Publication Type: Journal Article

Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049 (Electronic) Linking ISSN: 14203049 NLM ISO Abbreviation: Molecules Subsets: MEDLINE

Ψ and χ Angle Constrains at the C-Terminus Trp Position of the Melanotropin Tetrapeptide Ac-His-d-Phe-Arg-Trp-NH2 Lead to Potent and Selective Agonists at hMC1R and hMC4R.

Authors: Zhou Y Mowlazadeh Haghighi S Sawyer JR et al.

Source: Journal of medicinal chemistry [J Med Chem] 2023 May 25; Vol. 66 (10), pp. 6715-6724. Date of Electronic Publication: 2023 May 03.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

Protection against β-amyloid neurotoxicity by a non-toxic endogenous N-terminal β-amyloid fragment and its active hexapeptide core sequence.

Authors: Forest KH Alfulaij N Arora K et al.

Source: Journal of neurochemistry [J Neurochem] 2018 Jan; Vol. 144 (2), pp. 201-217. Date of Electronic Publication: 2017 Dec 18.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

Journal Info: Publisher: Wiley on behalf of the International Society for Neurochemistry Country of Publication: England NLM ID: 2985190R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1471-4159 (Electronic) Linking ISSN: 00223042 NLM ISO Abbreviation: J Neurochem Subsets: MEDLINE

CLIPSing Melanotan-II to Discover Multiple Functionally Selective hMCR Agonists.

Authors: Tomassi S Dimmito MP Cai M et al.

Source: Journal of medicinal chemistry [J Med Chem] 2022 Mar 10; Vol. 65 (5), pp. 4007-4017. Date of Electronic Publication: 2022 Feb 21.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

C-terminal modified Enkephalin-like tetrapeptides with enhanced affinities at the kappa opioid receptor and monoamine transporters.

Authors: Mehr-Un-Nisa Munawar MA Rankin D et al.

Source: Bioorganic & medicinal chemistry [Bioorg Med Chem] 2021 Dec 01; Vol. 51, pp. 116509. Date of Electronic Publication: 2021 Nov 11.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Elsevier Science Country of Publication: England NLM ID: 9413298 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1464-3391 (Electronic) Linking ISSN: 09680896 NLM ISO Abbreviation: Bioorg Med Chem Subsets: MEDLINE

Design of cyclized selective melanotropins.

Authors: Cai M Hruby VJ

Source: Biopolymers [Biopolymers] 2016 Nov; Vol. 106 (6), pp. 876-883.

Publication Type: Journal Article; Review

Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 0372525 Publication Model: Print Cited Medium: Internet ISSN: 1097-0282 (Electronic) Linking ISSN: 00063525 NLM ISO Abbreviation: Biopolymers Subsets: MEDLINE

Design of cyclic peptides with biological activities from biologically active peptides: the case of peptide modulators of melanocortin receptors.

Authors: Hruby VJ; Department of Chemistry and Biochemistry, University of Arizona, 1306 East University Boulevard, Tucson, Arizona, 85721, USA.

Source: Biopolymers [Biopolymers] 2016 Nov; Vol. 106 (6), pp. 884-888.

Publication Type: Journal Article; Review

Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 0372525 Publication Model: Print Cited Medium: Internet ISSN: 1097-0282 (Electronic) Linking ISSN: 00063525 NLM ISO Abbreviation: Biopolymers Subsets: MEDLINE

Various modifications of the amphipathic dynorphin A pharmacophore for rat brain bradykinin receptors.

Authors: Lee YS Kupp R Remesic MV et al.

Source: Chemical biology & drug design [Chem Biol Drug Des] 2016 Oct; Vol. 88 (4), pp. 615-9. Date of Electronic Publication: 2016 Jun 06.

Publication Type: Letter; Research Support, N.I.H., Extramural

Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101262549 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1747-0285 (Electronic) Linking ISSN: 17470277 NLM ISO Abbreviation: Chem Biol Drug Des Subsets: MEDLINE

Multiple Applications of a Novel Biarsenical Imaging Probe in Fluorescence and PET Imaging of Melanoma.

Authors: Kondrashov M Svensson SPS Ström P et al.

Source: Bioconjugate chemistry [Bioconjug Chem] 2021 Mar 17; Vol. 32 (3), pp. 497-501. Date of Electronic Publication: 2021 Feb 12.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9010319 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4812 (Electronic) Linking ISSN: 10431802 NLM ISO Abbreviation: Bioconjug Chem Subsets: MEDLINE

Cancer vaccine adjuvants--recent clinical progress and future perspectives.

Authors: Banday AH Jeelani S Hruby VJ

Source: Immunopharmacology and immunotoxicology [Immunopharmacol Immunotoxicol] 2015 Feb; Vol. 37 (1), pp. 1-11. Date of Electronic Publication: 2014 Oct 16.

Publication Type: Journal Article; Review

Journal Info: Publisher: Informa Healthcare Country of Publication: England NLM ID: 8800150 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-2513 (Electronic) Linking ISSN: 08923973 NLM ISO Abbreviation: Immunopharmacol Immunotoxicol Subsets: MEDLINE

Adventures in peptides and science with students! The joys of research.

Authors: Hruby VJ; Department of Chemistry and Biochemistry, University of Arizona, Tucson, AZ, 85721.

Source: Biopolymers [Biopolymers] 2013 Apr; Vol. 100 (2), pp. 127-31.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 0372525 Publication Model: Print Cited Medium: Internet ISSN: 1097-0282 (Electronic) Linking ISSN: 00063525 NLM ISO Abbreviation: Biopolymers Subsets: MEDLINE

α-Melanocyte-stimulating hormone regulates vascular NO availability and protects against endothelial dysfunction.

Authors: Rinne P Nordlund W Heinonen I et al.

Source: Cardiovascular research [Cardiovasc Res] 2013 Feb 01; Vol. 97 (2), pp. 360-8. Date of Electronic Publication: 2012 Nov 05.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

Journal Info: Publisher: Oxford Journals Country of Publication: England NLM ID: 0077427 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1755-3245 (Electronic) Linking ISSN: 00086363 NLM ISO Abbreviation: Cardiovasc Res Subsets: MEDLINE

New potent biphalin analogues containing p-fluoro-L-phenylalanine at the 4,4' positions and non-hydrazine linkers.

Authors: Mollica A Pinnen F Feliciani F et al.

Source: Amino acids [Amino Acids] 2011 May; Vol. 40 (5), pp. 1503-11. Date of Electronic Publication: 2010 Oct 06.

Publication Type: Journal Article; Research Support, N.I.H., Extramural

Journal Info: Publisher: Springer-Verlag Country of Publication: Austria NLM ID: 9200312 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1438-2199 (Electronic) Linking ISSN: 09394451 NLM ISO Abbreviation: Amino Acids Subsets: MEDLINE

Development of Ligand-Drug Conjugates Targeting Melanoma through the Overexpressed Melanocortin 1 Receptor.

Authors: Zhou Y Mowlazadeh Haghighi S Liu Z et al.

Source: ACS pharmacology & translational science [ACS Pharmacol Transl Sci] 2020 Aug 18; Vol. 3 (5), pp. 921-930. Date of Electronic Publication: 2020 Aug 18 (Print Publication: 2020).

Publication Type: Journal Article

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101721411 Publication Model: eCollection Cited Medium: Internet ISSN: 2575-9108 (Electronic) Linking ISSN: 25759108 NLM ISO Abbreviation: ACS Pharmacol Transl Sci Subsets: PubMed not MEDLINE

Melanocortin 3 receptor activation with [D-Trp8]-γ-MSH suppresses inflammation in apolipoprotein E deficient mice.

Authors: Kadiri JJ Thapa K Kaipio K et al.

Source: European journal of pharmacology [Eur J Pharmacol] 2020 Aug 05; Vol. 880, pp. 173186. Date of Electronic Publication: 2020 May 13.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 1254354 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0712 (Electronic) Linking ISSN: 00142999 NLM ISO Abbreviation: Eur J Pharmacol Subsets: MEDLINE