Search Results - "Humke EW"

The exocyst complex and intracellular vesicles mediate soluble protein trafficking to the primary cilium.

Authors: Niedziółka SM Datta S Uśpieński T et al.

Source: Communications biology [Commun Biol] 2024 Feb 21; Vol. 7 (1), pp. 213. Date of Electronic Publication: 2024 Feb 21.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

Journal Info: Publisher: Nature Publishing Group UK Country of Publication: England NLM ID: 101719179 Publication Model: Electronic Cited Medium: Internet ISSN: 2399-3642 (Electronic) Linking ISSN: 23993642 NLM ISO Abbreviation: Commun Biol Subsets: MEDLINE

An Open-label Phase I Study of GDC-0927 in Postmenopausal Women with Locally Advanced or Metastatic Estrogen Receptor-Positive Breast Cancer.

Authors: Chandarlapaty S Dickler MN Perez Fidalgo JA et al.

Source: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2023 Aug 01; Vol. 29 (15), pp. 2781-2790.

Publication Type: Multicenter Study; Clinical Trial, Phase I; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 9502500 Publication Model: Print Cited Medium: Internet ISSN: 1557-3265 (Electronic) Linking ISSN: 10780432 NLM ISO Abbreviation: Clin Cancer Res Subsets: MEDLINE

Phase I study of the anti-FcRH5 antibody-drug conjugate DFRF4539A in relapsed or refractory multiple myeloma.

Authors: Stewart AK Krishnan AY Singhal S et al.

Source: Blood cancer journal [Blood Cancer J] 2019 Feb 04; Vol. 9 (2), pp. 17. Date of Electronic Publication: 2019 Feb 04.

Publication Type: Clinical Trial, Phase I; Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101568469 Publication Model: Electronic Cited Medium: Internet ISSN: 2044-5385 (Electronic) Linking ISSN: 20445385 NLM ISO Abbreviation: Blood Cancer J Subsets: MEDLINE

Multimeric Anti-DR5 IgM Agonist Antibody IGM-8444 Is a Potent Inducer of Cancer Cell Apoptosis and Synergizes with Chemotherapy and BCL-2 Inhibitor ABT-199.

Authors: Wang BT Kothambawala T Wang L et al.

Source: Molecular cancer therapeutics [Mol Cancer Ther] 2021 Dec; Vol. 20 (12), pp. 2483-2494. Date of Electronic Publication: 2021 Oct 28.

Publication Type: Journal Article

Journal Info: Publisher: American Association for Cancer Research, Inc Country of Publication: United States NLM ID: 101132535 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-8514 (Electronic) Linking ISSN: 15357163 NLM ISO Abbreviation: Mol Cancer Ther Subsets: MEDLINE

Phase 1b study of anti-NaPi2b antibody-drug conjugate lifastuzumab vedotin (DNIB0600A) in patients with platinum-sensitive recurrent ovarian cancer.

Authors: Moore KN Birrer MJ Marsters J et al.

Source: Gynecologic oncology [Gynecol Oncol] 2020 Sep; Vol. 158 (3), pp. 631-639. Date of Electronic Publication: 2020 Jun 11.

Publication Type: Clinical Trial, Phase I; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Academic Press Country of Publication: United States NLM ID: 0365304 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-6859 (Electronic) Linking ISSN: 00908258 NLM ISO Abbreviation: Gynecol Oncol Subsets: MEDLINE

Kif3a is necessary for initiation and maintenance of medulloblastoma.

Authors: Barakat MT Humke EW Scott MP

Source: Carcinogenesis [Carcinogenesis] 2013 Jun; Vol. 34 (6), pp. 1382-92. Date of Electronic Publication: 2013 Feb 06.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

Journal Info: Publisher: Irl Press At Oxford University Press Country of Publication: England NLM ID: 8008055 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1460-2180 (Electronic) Linking ISSN: 01433334 NLM ISO Abbreviation: Carcinogenesis Subsets: MEDLINE

Phase Ia Study of Anti-NaPi2b Antibody-Drug Conjugate Lifastuzumab Vedotin DNIB0600A in Patients with Non-Small Cell Lung Cancer and Platinum-Resistant Ovarian Cancer.

Authors: Gerber DE Infante JR Gordon MS et al.

Source: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2020 Jan 15; Vol. 26 (2), pp. 364-372. Date of Electronic Publication: 2019 Sep 20.

Publication Type: Clinical Trial, Phase I; Journal Article; Multicenter Study

Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 9502500 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1557-3265 (Electronic) Linking ISSN: 10780432 NLM ISO Abbreviation: Clin Cancer Res Subsets: MEDLINE

Anti-NaPi2b antibody-drug conjugate lifastuzumab vedotin (DNIB0600A) compared with pegylated liposomal doxorubicin in patients with platinum-resistant ovarian cancer in a randomized, open-label, phase II study.

Authors: Banerjee S Oza AM Birrer MJ et al.

Source: Annals of oncology : official journal of the European Society for Medical Oncology [Ann Oncol] 2018 Apr 01; Vol. 29 (4), pp. 917-923.

Publication Type: Clinical Trial, Phase II; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Elsevier Country of Publication: England NLM ID: 9007735 Publication Model: Print Cited Medium: Internet ISSN: 1569-8041 (Electronic) Linking ISSN: 09237534 NLM ISO Abbreviation: Ann Oncol Subsets: MEDLINE

Phase I study of safety and pharmacokinetics of the anti-MUC16 antibody-drug conjugate DMUC5754A in patients with platinum-resistant ovarian cancer or unresectable pancreatic cancer.

Authors: Liu JF Moore KN Birrer MJ et al.

Source: Annals of oncology : official journal of the European Society for Medical Oncology [Ann Oncol] 2016 Nov; Vol. 27 (11), pp. 2124-2130.

Publication Type: Clinical Trial, Phase I; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Elsevier Country of Publication: England NLM ID: 9007735 Publication Model: Print Cited Medium: Internet ISSN: 1569-8041 (Electronic) Linking ISSN: 09237534 NLM ISO Abbreviation: Ann Oncol Subsets: MEDLINE

Gli protein activity is controlled by multisite phosphorylation in vertebrate Hedgehog signaling.

Authors: Niewiadomski P Kong JH Ahrends R et al.

Source: Cell reports [Cell Rep] 2014 Jan 16; Vol. 6 (1), pp. 168-181. Date of Electronic Publication: 2013 Dec 27.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE

Isolation and mutational analysis of circulating tumor cells from lung cancer patients with magnetic sifters and biochips.

Authors: Earhart CM Hughes CE Gaster RS et al.

Source: Lab on a chip [Lab Chip] 2014 Jan 07; Vol. 14 (1), pp. 78-88.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

Journal Info: Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101128948 Publication Model: Print Cited Medium: Internet ISSN: 1473-0189 (Electronic) Linking ISSN: 14730189 NLM ISO Abbreviation: Lab Chip Subsets: MEDLINE

Learning from Jekyll to control Hyde: Hedgehog signaling in development and cancer.

Authors: Barakat MT Humke EW Scott MP

Source: Trends in molecular medicine [Trends Mol Med] 2010 Aug; Vol. 16 (8), pp. 337-48. Date of Electronic Publication: 2010 Jun 16.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Review

Journal Info: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 100966035 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1471-499X (Electronic) Linking ISSN: 14714914 NLM ISO Abbreviation: Trends Mol Med Subsets: MEDLINE

The output of Hedgehog signaling is controlled by the dynamic association between Suppressor of Fused and the Gli proteins.

Authors: Humke EW Dorn KV Milenkovic L et al.

Source: Genes & development [Genes Dev] 2010 Apr 01; Vol. 24 (7), pp. 670-82.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Cold Spring Harbor Laboratory Press Country of Publication: United States NLM ID: 8711660 Publication Model: Print Cited Medium: Internet ISSN: 1549-5477 (Electronic) Linking ISSN: 08909369 NLM ISO Abbreviation: Genes Dev Subsets: MEDLINE

A NOD2-NALP1 complex mediates caspase-1-dependent IL-1beta secretion in response to Bacillus anthracis infection and muramyl dipeptide.

Authors: Hsu LC Ali SR McGillivray S et al.

Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2008 Jun 03; Vol. 105 (22), pp. 7803-8. Date of Electronic Publication: 2008 May 29.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

The PYRIN domain: a member of the death domain-fold superfamily.

Authors: Fairbrother WJ Gordon NC Humke EW et al.

Source: Protein science : a publication of the Protein Society [Protein Sci] 2001 Sep; Vol. 10 (9), pp. 1911-8.

Publication Type: Journal Article

Journal Info: Publisher: Cold Spring Harbor Laboratory Press Country of Publication: United States NLM ID: 9211750 Publication Model: Print Cited Medium: Print ISSN: 0961-8368 (Print) Linking ISSN: 09618368 NLM ISO Abbreviation: Protein Sci Subsets: MEDLINE

ICEBERG: a novel inhibitor of interleukin-1beta generation.

Authors: Humke EW Shriver SK Starovasnik MA et al.

Source: Cell [Cell] 2000 Sep 29; Vol. 103 (1), pp. 99-111.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 0413066 Publication Model: Print Cited Medium: Print ISSN: 0092-8674 (Print) Linking ISSN: 00928674 NLM ISO Abbreviation: Cell Subsets: MEDLINE

Web Alert. Apoptosis.

Authors: Humke EW; Department of Molecular Oncology, Genetech, Inc. South San Francisco, CA 94080, USA. ehumke@gene.com

Source: Chemistry & biology [Chem Biol] 2000 Feb; Vol. 7 (2), pp. R48-9.

Publication Type: Directory

Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 9500160 Publication Model: Print Cited Medium: Print ISSN: 1074-5521 (Print) Linking ISSN: 10745521 NLM ISO Abbreviation: Chem Biol Subsets: MEDLINE

Caspase-9 can be activated without proteolytic processing.

Authors: Stennicke HR Deveraux QL Humke EW et al.

Source: The Journal of biological chemistry [J Biol Chem] 1999 Mar 26; Vol. 274 (13), pp. 8359-62.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.

Journal Info: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print Cited Medium: Print ISSN: 0021-9258 (Print) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE

ERICE, a novel FLICE-activatable caspase.

Authors: Humke EW Ni J Dixit VM

Source: The Journal of biological chemistry [J Biol Chem] 1998 Jun 19; Vol. 273 (25), pp. 15702-7.

Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.

Journal Info: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print Cited Medium: Print ISSN: 0021-9258 (Print) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE

Activation of caspases triggered by cytochrome c in vitro.

Authors: Pan G Humke EW Dixit VM

Source: FEBS letters [FEBS Lett] 1998 Apr 10; Vol. 426 (1), pp. 151-4.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

Journal Info: Publisher: John Wiley & Sons Ltd Country of Publication: England NLM ID: 0155157 Publication Model: Print Cited Medium: Print ISSN: 0014-5793 (Print) Linking ISSN: 00145793 NLM ISO Abbreviation: FEBS Lett Subsets: MEDLINE