Search Results - "Humke EW"

Smoothened and ciliary GPCRs regulate ciliary protein kinase A activity involved in Hedgehog signal transduction.

Authors: Nguyen, Thi D. Konjikusic, Mia J. Del Castillo, Lorenzo M. et al.

Source: PLoS Biology. 6/10/2026, Vol. 24 Issue 6, p1-26. 26p.

CMKLR1/PKA signaling reinforces sonic hedgehog pathway to promote medulloblastoma pathogenesis.

Authors: Wang, Shan Jiang, Tongtong Wang, Tao et al.

Source: Oncogenesis. 11/17/2025, Vol. 14 Issue 1, p1-13. 13p.

Aponermin or placebo in combination with thalidomide and dexamethasone in the treatment of relapsed or refractory multiple myeloma (CPT-MM301): a randomised, double-blinded, placebo-controlled, phase 3 trial.

Authors: Xia, Zhongjun Leng, Yun Fang, Baijun et al.

Source: BMC Cancer. 10/14/2023, Vol. 23 Issue 1, p1-14. 14p.

Context-dependent ciliary regulation of hedgehog pathway repression in tissue morphogenesis.

Authors: Hwang, Sun-Hee White, Kevin Andrew Somatilaka, Bandarigoda Nipunika et al.

Source: PLoS Genetics. 11/9/2023, Vol. 19 Issue 11, p1-25. 25p.

GRK2 kinases in the primary cilium initiate SMOOTHENED-PKA signaling in the Hedgehog cascade.

Authors: Walker, Madison F. Zhang, Jingyi Steiner, William et al.

Source: PLoS Biology. 8/13/2024, Vol. 22 Issue 8, p1-41. 41p.

NOD2-Related Multisystem Inflammatory Disorders and Recent Advances.

Authors: Wu D Matsuda T Xie D et al.

Source: Current rheumatology reports [Curr Rheumatol Rep] 2026 Feb 12; Vol. 28 (1), pp. 5. Date of Electronic Publication: 2026 Feb 12.

Publication Type: Journal Article; Review

Journal Info: Publisher: Current Science Country of Publication: United States NLM ID: 100888970 Publication Model: Electronic Cited Medium: Internet ISSN: 1534-6307 (Electronic) Linking ISSN: 15233774 NLM ISO Abbreviation: Curr Rheumatol Rep Subsets: MEDLINE

Rescue of ciliogenesis and hyperglutamylation mutant phenotype in AGBL5^−/− cell model of retinitis pigmentosa.

Authors: Villa-Vasquez, Suly S. Nazlamova, Liliya Pengelly, Reuben J. et al.

Source: BMC Molecular & Cell Biology. 9/9/2025, Vol. 26 Issue 1, p1-22. 22p.

Nuclear PYHIN proteins target the host transcription factor Sp1 thereby restricting HIV-1 in human macrophages and CD4+ T cells.

Authors: Bosso, Matteo Prelli Bozzo, Caterina Hotter, Dominik et al.

Source: PLoS Pathogens. 8/6/2020, Vol. 16 Issue 8, p1-30. 30p.

CD56 polysialylation promotes the tumorigenesis and progression via the Hedgehog and Wnt/β-catenin signaling pathways in clear cell renal cell carcinoma.

Authors: Jian, Yuli Zhang, Lin Gong, Li et al.

Source: Cancer Cell International. 12/12/2023, Vol. 23 Issue 1, p1-17. 17p.

Ehrlichia SLiM ligand mimetic activates Hedgehog signaling to engage a BCL-2 anti-apoptotic cellular program.

Authors: Byerly, Caitlan D. Mitra, Shubhajit Patterson, LaNisha L. et al.

Source: PLoS Pathogens. 5/16/2022, Vol. 18 Issue 5, p1-31. 31p.

Loss of KAP3 decreases intercellular adhesion and impairs intracellular transport of laminin in signet ring cell carcinoma of the stomach.

Authors: Soda, Tomohiro Gen, Yasuyuki Terasaki, Kei et al.

Source: Scientific Reports. 3/23/2022, Vol. 12 Issue 1, p1-12. 12p.

Peptidoglycan-based immunomodulation.

Authors: Sun, Qingshen Liu, Xiaoli Li, Xiuliang

Source: Applied Microbiology & Biotechnology; Feb2022, Vol. 106 Issue 3, p981-993, 13p

Hedgehog-stimulated phosphorylation at multiple sites activates Ci by altering Ci–Ci interfaces without full Suppressor of Fused dissociation.

Authors: Kim, Hoyon Little, Jamie C. Li, Jiashen et al.

Source: PLoS Biology. 4/11/2025, Vol. 23 Issue 4, p1-37. 37p.

Regulatory mechanisms governing GLI proteins in hedgehog signaling.

Authors: Yoshida, Saishu Yoshida, Kiyotsugu

Source: Anatomical Science International. Mar2025, Vol. 100 Issue 2, p143-154. 12p.

Hedgehog pathway activity downstream of Smoothened is regulated specifically by basal ciliary PKA.

Authors: Zhang H Chen S Huang Z et al.

Source: Cellular & molecular biology letters [Cell Mol Biol Lett] 2026 Apr 09; Vol. 31 (1). Date of Electronic Publication: 2026 Apr 09.

Publication Type: Journal Article

Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 9607427 Publication Model: Electronic Cited Medium: Internet ISSN: 1689-1392 (Electronic) Linking ISSN: 14258153 NLM ISO Abbreviation: Cell Mol Biol Lett Subsets: MEDLINE

The Hira complex regulates Gli3R-dependent transcription in Hedgehog signaling and medulloblastoma cell growth and migration.

Authors: Skarżyńska, Weronika Baran, Brygida Niewiadomski, Paweł

Source: Scientific Reports. 1/2/2025, Vol. 15 Issue 1, p1-15. 15p.

Microscopic marvels: Decoding the role of micropeptides in innate immunity.

Authors: Naidu, Praveena Holford, Mandë

Source: Immunology. Dec2024, Vol. 173 Issue 4, p605-621. 17p.

Sonic hedgehog signalling pathway in CNS tumours: its role and therapeutic implications.

Authors: Wireko, Andrew Awuah Ben-Jaafar, Adam Kong, Jonathan Sing Huk et al.

Source: Molecular Brain. 11/20/2024, Vol. 17 Issue 1, p1-22. 22p.

Kinesin family member 3A induces related diseases via wingless-related integration site/β-catenin signaling pathway.

Authors: Liu, Shupeng He, Yang Li, Shifeng et al.

Source: Science Progress. Jan-Mar2023, Vol. 106 Issue 1, p1-20. 20p.

Clonal variations in CHO IGF signaling investigated by SILAC-based phosphoproteomics and LFQ-MS.

Authors: Schelletter, Louise Albaum, Stefan Walter, Stefan et al.

Source: Applied Microbiology & Biotechnology; Oct2019, Vol. 103 Issue 19, p8127-8143, 17p