Search Results - "Huntsman-Labed A"

Midostaurin does not prolong cardiac repolarization defined in a thorough electrocardiogram trial in healthy volunteers.

Authors: del Corral, Adam Dutreix, Catherine Huntsman-Labed, Alice et al.

Source: Cancer Chemotherapy & Pharmacology. May2012, Vol. 69 Issue 5, p1255-1263. 9p.

Pharmacokinetics and Exposure–Response of Vosoritide in Children with Achondroplasia.

Authors: Chan, Ming Liang Qi, Yulan Larimore, Kevin et al.

Source: Clinical Pharmacokinetics. Feb2022, Vol. 61 Issue 2, p263-280. 18p.

Phase IB study of the FLT3 kinase inhibitor midostaurin with chemotherapy in younger newly diagnosed adult patients with acute myeloid leukemia.

Authors: Stone, R M Fischer, T Paquette, R et al.

Source: Leukemia (08876924). Sep2012, Vol. 26 Issue 9, p2061-2068. 8p. 1 Diagram, 4 Charts, 3 Graphs.

Efficacy and Safety of Midostaurin in Advanced Systemic Mastocytosis.

Authors: Gotlib, Jason Kluin-Nelemans, Hanneke C. George, Tracy I. et al.

Source: New England Journal of Medicine. 6/30/2016, Vol. 374 Issue 26, p2530-2541. 12p.

Metabolic syndrome and alanine aminotransferase: a global perspective from the NAVIGATOR screening population.

Authors: Bethel, M. A. Deedwania, P. Levitt, N. S. et al.

Source: Diabetic Medicine. Dec2009, Vol. 26 Issue 12, p1204-1211. 8p. 4 Charts.

Sustained growth-promoting effects of vosoritide in children with achondroplasia from an ongoing phase 3 extension study.

Authors: Savarirayan R Irving M Wilcox WR et al.

Source: Med (New York, N.Y.) [Med] 2025 May 09; Vol. 6 (5), pp. 100566. Date of Electronic Publication: 2024 Dec 30.

Publication Type: Journal Article; Clinical Trial, Phase III; Randomized Controlled Trial; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101769215 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2666-6340 (Electronic) Linking ISSN: 26666340 NLM ISO Abbreviation: Med Subsets: MEDLINE

Persistent growth-promoting effects of vosoritide in children with achondroplasia are accompanied by improvements in physical and social aspects of health-related quality of life.

Authors: Savarirayan R Irving M Wilcox WR et al.

Source: Genetics in medicine : official journal of the American College of Medical Genetics [Genet Med] 2024 Dec; Vol. 26 (12), pp. 101274. Date of Electronic Publication: 2024 Sep 18.

Publication Type: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 9815831 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1530-0366 (Electronic) Linking ISSN: 10983600 NLM ISO Abbreviation: Genet Med Subsets: MEDLINE

Vosoritide therapy in children with achondroplasia aged 3-59 months: a multinational, randomised, double-blind, placebo-controlled, phase 2 trial.

Authors: Savarirayan R Wilcox WR Harmatz P et al.

Source: The Lancet. Child & adolescent health [Lancet Child Adolesc Health] 2024 Jan; Vol. 8 (1), pp. 40-50. Date of Electronic Publication: 2023 Nov 18.

Publication Type: Clinical Trial, Phase II; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Elsevier Ltd Country of Publication: England NLM ID: 101712925 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2352-4650 (Electronic) Linking ISSN: 23524642 NLM ISO Abbreviation: Lancet Child Adolesc Health Subsets: MEDLINE

Growth parameters in children with achondroplasia: A 7-year, prospective, multinational, observational study.

Authors: Savarirayan R Irving M Harmatz P et al.

Source: Genetics in medicine : official journal of the American College of Medical Genetics [Genet Med] 2022 Dec; Vol. 24 (12), pp. 2444-2452. Date of Electronic Publication: 2022 Sep 16.

Publication Type: Observational Study; Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 9815831 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1530-0366 (Electronic) Linking ISSN: 10983600 NLM ISO Abbreviation: Genet Med Subsets: MEDLINE

Safe and persistent growth-promoting effects of vosoritide in children with achondroplasia: 2-year results from an open-label, phase 3 extension study.

Authors: Savarirayan R Tofts L Irving M et al.

Source: Genetics in medicine : official journal of the American College of Medical Genetics [Genet Med] 2021 Dec; Vol. 23 (12), pp. 2443-2447. Date of Electronic Publication: 2021 Aug 02.

Publication Type: Clinical Trial, Phase III; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 9815831 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1530-0366 (Electronic) Linking ISSN: 10983600 NLM ISO Abbreviation: Genet Med Subsets: MEDLINE

Once-daily, subcutaneous vosoritide therapy in children with achondroplasia: a randomised, double-blind, phase 3, placebo-controlled, multicentre trial.

Authors: Savarirayan R Tofts L Irving M et al.

Source: Lancet (London, England) [Lancet] 2020 Sep 05; Vol. 396 (10252), pp. 684-692.

Publication Type: Clinical Trial, Phase III; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Elsevier Country of Publication: England NLM ID: 2985213R Publication Model: Print Cited Medium: Internet ISSN: 1474-547X (Electronic) Linking ISSN: 01406736 NLM ISO Abbreviation: Lancet Subsets: MEDLINE

C-Type Natriuretic Peptide Analogue Therapy in Children with Achondroplasia.

Authors: Savarirayan R Irving M Bacino CA et al.

Source: The New England journal of medicine [N Engl J Med] 2019 Jul 04; Vol. 381 (1), pp. 25-35. Date of Electronic Publication: 2019 Jun 18.

Publication Type: Clinical Trial, Phase II; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Massachusetts Medical Society Country of Publication: United States NLM ID: 0255562 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1533-4406 (Electronic) Linking ISSN: 00284793 NLM ISO Abbreviation: N Engl J Med

Phase IIB trial of oral Midostaurin (PKC412), the FMS-like tyrosine kinase 3 receptor (FLT3) and multi-targeted kinase inhibitor, in patients with acute myeloid leukemia and high-risk myelodysplastic syndrome with either wild-type or mutated FLT3.

Authors: Fischer T Stone RM Deangelo DJ et al.

Source: Journal of clinical oncology : official journal of the American Society of Clinical Oncology [J Clin Oncol] 2010 Oct 01; Vol. 28 (28), pp. 4339-45. Date of Electronic Publication: 2010 Aug 23.

Publication Type: Clinical Trial, Phase II; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Society of Clinical Oncology Country of Publication: United States NLM ID: 8309333 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1527-7755 (Electronic) Linking ISSN: 0732183X NLM ISO Abbreviation: J Clin Oncol Subsets: MEDLINE

Determining the most appropriate components for a composite clinical trial outcome.

Authors: Bethel MA Holman R Haffner SM et al.

Source: American heart journal [Am Heart J] 2008 Oct; Vol. 156 (4), pp. 633-40. Date of Electronic Publication: 2008 Jul 31.

Publication Type: Journal Article; Meta-Analysis; Randomized Controlled Trial

Journal Info: Publisher: Mosby Country of Publication: United States NLM ID: 0370465 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-6744 (Electronic) Linking ISSN: 00028703 NLM ISO Abbreviation: Am Heart J Subsets: MEDLINE