Search Results - "Keyes RF"

Mitochondria-targeted metformin analogs activate the ER stress-unfolded protein response pathway to drive apoptosis in pancreatic cancer.

Authors: Poimenidou M Bobek JM Drouillard D et al.

Source: Cell death & disease [Cell Death Dis] 2026 May 22; Vol. 17 (1). Date of Electronic Publication: 2026 May 22.

Publication Type: Journal Article

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-4889 (Electronic) NLM ISO Abbreviation: Cell Death Dis Subsets: MEDLINE

Reutericyclin, a specialized metabolite of Limosilactobacillus reuteri, mitigates risperidone-induced weight gain in mice.

Authors: Aboulalazm FA Kazen AB deLeon O et al.

Source: Gut microbes [Gut Microbes] 2025 Dec; Vol. 17 (1), pp. 2477819. Date of Electronic Publication: 2025 Apr 07.

Publication Type: Journal Article

Journal Info: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101495343 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1949-0984 (Electronic) Linking ISSN: 19490976 NLM ISO Abbreviation: Gut Microbes Subsets: MEDLINE

Polybromo‑1 Bromodomain Inhibitor Selectivity Is Mediated by a Unique Ligand-Binding Pocket.

Authors: Nuñez R Bursch KL Makowski SJ et al.

Source: ACS medicinal chemistry letters [ACS Med Chem Lett] 2025 Sep 16; Vol. 16 (10), pp. 1955-1962. Date of Electronic Publication: 2025 Sep 16 (Print Publication: 2025).

Publication Type: Journal Article

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101521073 Publication Model: eCollection Cited Medium: Print ISSN: 1948-5875 (Print) Linking ISSN: 19485875 NLM ISO Abbreviation: ACS Med Chem Lett Subsets: PubMed not MEDLINE

The TRIM33 Bromodomain Recognizes Histone Lysine Lactylation.

Authors: Nuñez R Sidlowski PFW Steen EA et al.

Source: ACS chemical biology [ACS Chem Biol] 2024 Dec 20; Vol. 19 (12), pp. 2418-2428. Date of Electronic Publication: 2024 Nov 18.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101282906 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1554-8937 (Electronic) Linking ISSN: 15548929 NLM ISO Abbreviation: ACS Chem Biol Subsets: MEDLINE

Lipid Trolling to Optimize A3 Adenosine Receptor-Positive Allosteric Modulators (PAMs).

Authors: Pradhan B Pavan M Fisher CL et al.

Source: Journal of medicinal chemistry [J Med Chem] 2024 Jul 25; Vol. 67 (14), pp. 12221-12247. Date of Electronic Publication: 2024 Jul 03.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

Extrahelical Binding Site for a 1H-Imidazo[4,5-c]quinolin-4-amine A3 Adenosine Receptor Positive Allosteric Modulator on Helix 8 and Distal Portions of Transmembrane Domains 1 and 7.

Authors: Fisher CL Pavan M Salmaso V et al.

Source: Molecular pharmacology [Mol Pharmacol] 2024 Feb 15; Vol. 105 (3), pp. 213-223. Date of Electronic Publication: 2024 Feb 15.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Society for Pharmacology and Experimental Therapeutics Country of Publication: Netherlands NLM ID: 0035623 Publication Model: Electronic Cited Medium: Internet ISSN: 1521-0111 (Electronic) Linking ISSN: 0026895X NLM ISO Abbreviation: Mol Pharmacol Subsets: MEDLINE

Synthesis of fluorinated triphenylphosphonium analogs that improve cancer cell selectivity and in vivo detection.

Authors: Keyes RF McAllister D Dwinell MB et al.

Source: STAR protocols [STAR Protoc] 2023 Sep 15; Vol. 4 (3), pp. 102437. Date of Electronic Publication: 2023 Aug 07.

Publication Type: Journal Article; Research Support, N.I.H., Extramural

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101769501 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2666-1667 (Electronic) Linking ISSN: 26661667 NLM ISO Abbreviation: STAR Protoc Subsets: MEDLINE

Sulfenylation links oxidative stress to protein disulfide isomerase oxidase activity and thrombus formation.

Authors: Yang M Chiu J Scartelli C et al.

Source: Journal of thrombosis and haemostasis : JTH [J Thromb Haemost] 2023 Aug; Vol. 21 (8), pp. 2137-2150. Date of Electronic Publication: 2023 Apr 08.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Elsevier Country of Publication: England NLM ID: 101170508 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-7836 (Electronic) Linking ISSN: 15387836 NLM ISO Abbreviation: J Thromb Haemost Subsets: MEDLINE

Harnessing the Noncanonical Keap1-Nrf2 Pathway for Human Cytomegalovirus Control.

Authors: Ghosh AK Su YP Forman M et al.

Source: Journal of virology [J Virol] 2023 Apr 27; Vol. 97 (4), pp. e0016023. Date of Electronic Publication: 2023 Mar 20.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Society For Microbiology Country of Publication: United States NLM ID: 0113724 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1098-5514 (Electronic) Linking ISSN: 0022538X NLM ISO Abbreviation: J Virol Subsets: MEDLINE

Fluorinated triphenylphosphonium analogs improve cell selectivity and in vivo detection of mito-metformin.

Authors: AbuEid M Keyes RF McAllister D et al.

Source: IScience [iScience] 2022 Nov 26; Vol. 25 (12), pp. 105670. Date of Electronic Publication: 2022 Nov 26 (Print Publication: 2022).

Publication Type: Journal Article

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101724038 Publication Model: eCollection Cited Medium: Internet ISSN: 2589-0042 (Electronic) Linking ISSN: 25890042 NLM ISO Abbreviation: iScience Subsets: PubMed not MEDLINE

Characterization of Dual-Acting A3 Adenosine Receptor Positive Allosteric Modulators That Preferentially Enhance Adenosine-Induced Gαi3 and GαoA Isoprotein Activation.

Authors: Fisher CL Fallot LB Wan TC et al.

Source: ACS pharmacology & translational science [ACS Pharmacol Transl Sci] 2022 Jul 15; Vol. 5 (8), pp. 625-641. Date of Electronic Publication: 2022 Jul 15 (Print Publication: 2022).

Publication Type: Journal Article

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101721411 Publication Model: eCollection Cited Medium: Internet ISSN: 2575-9108 (Electronic) Linking ISSN: 25759108 NLM ISO Abbreviation: ACS Pharmacol Transl Sci Subsets: PubMed not MEDLINE

The Synthesis and Anti-Cytomegalovirus Activity of Piperidine-4-Carboxamides.

Authors: Guo X Ghosh AK Keyes RF et al.

Source: Viruses [Viruses] 2022 Jan 25; Vol. 14 (2). Date of Electronic Publication: 2022 Jan 25.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101509722 Publication Model: Electronic Cited Medium: Internet ISSN: 1999-4915 (Electronic) Linking ISSN: 19994915 NLM ISO Abbreviation: Viruses Subsets: MEDLINE

Validation and Characterization of Five Distinct Novel Inhibitors of Human Cytomegalovirus.

Authors: Kapoor A Ghosh AK Forman M et al.

Source: Journal of medicinal chemistry [J Med Chem] 2020 Apr 23; Vol. 63 (8), pp. 3896-3907. Date of Electronic Publication: 2020 Mar 27.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't; Validation Study

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

The synthesis and structure-activity relationship studies of selective acetyl-CoA carboxylase inhibitors containing 4-(thiazol-5-yl)but-3-yn-2-amino motif: polar region modifications.

Authors: Xu X Weitzberg M Keyes RF et al.

Source: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2007 Mar 15; Vol. 17 (6), pp. 1803-7. Date of Electronic Publication: 2006 Dec 21.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 9107377 Publication Model: Print-Electronic Cited Medium: Print ISSN: 0960-894X (Print) Linking ISSN: 0960894X NLM ISO Abbreviation: Bioorg Med Chem Lett Subsets: MEDLINE

N-{3-[2-(4-alkoxyphenoxy)thiazol-5-yl]-1-methylprop-2-ynyl}carboxy derivatives as acetyl-coA carboxylase inhibitors--improvement of cardiovascular and neurological liabilities via structural modifications.

Authors: Gu YG Weitzberg M Clark RF et al.

Source: Journal of medicinal chemistry [J Med Chem] 2007 Mar 08; Vol. 50 (5), pp. 1078-82. Date of Electronic Publication: 2007 Feb 14.

Publication Type: Journal Article

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Print ISSN: 0022-2623 (Print) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

Short and efficient synthesis of a vinyl-substituted tricyclic erythromycin derivative.

Authors: Keyes RF Carter JJ Zhang X et al.

Source: Organic letters [Org Lett] 2005 Mar 03; Vol. 7 (5), pp. 847-9.

Publication Type: Journal Article

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 100890393 Publication Model: Print Cited Medium: Print ISSN: 1523-7060 (Print) Linking ISSN: 15237052 NLM ISO Abbreviation: Org Lett Subsets: MEDLINE

Synthesis and antibacterial activity of 6-O-arylbutynyl ketolides with improved activity against some key erythromycin-resistant pathogens.

Authors: Keyes RF Carter JJ Englund EE et al.

Source: Journal of medicinal chemistry [J Med Chem] 2003 May 08; Vol. 46 (10), pp. 1795-8.

Publication Type: Journal Article

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print Cited Medium: Print ISSN: 0022-2623 (Print) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

Exploration of the effects of linker chain modifications on anti-HIV activities in a series of cosalane analogues.

Authors: Golebiewski WM Keyes RF Cushman M

Source: Bioorganic & medicinal chemistry [Bioorg Med Chem] 1996 Oct; Vol. 4 (10), pp. 1637-48.

Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.

Journal Info: Publisher: Elsevier Science Country of Publication: England NLM ID: 9413298 Publication Model: Print Cited Medium: Print ISSN: 0968-0896 (Print) Linking ISSN: 09680896 NLM ISO Abbreviation: Bioorg Med Chem Subsets: MEDLINE

Correlation of anti-HIV potency with lipophilicity in a series of cosalane analogs having normal alkenyl and phosphodiester chains as cholestane replacements.

Authors: Keyes RF Golebiewski WM Cushman M

Source: Journal of medicinal chemistry [J Med Chem] 1996 Jan 19; Vol. 39 (2), pp. 508-14.

Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print Cited Medium: Print ISSN: 0022-2623 (Print) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

Carcinogenicity tests of fecapentaene-12 in mice and rats.

Authors: Weisburger JH Jones RC Wang CX et al.

Source: Cancer letters [Cancer Lett] 1990 Feb; Vol. 49 (2), pp. 89-98.

Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.

Journal Info: Publisher: Elsevier Science Ireland Country of Publication: Ireland NLM ID: 7600053 Publication Model: Print Cited Medium: Print ISSN: 0304-3835 (Print) Linking ISSN: 03043835 NLM ISO Abbreviation: Cancer Lett Subsets: MEDLINE