Search Results - "Lay AC"

Evaluating Kidney Responses to Angiotensin-Converting Enzyme Inhibition at the Single-Cell Level.

Authors: Lay AC Tomaszewski M

Source: Journal of the American Society of Nephrology : JASN [J Am Soc Nephrol] 2026 Jul 01; Vol. 37 (7), pp. 1370-1372. Date of Electronic Publication: 2026 May 29.

Publication Type: Journal Article

Journal Info: Publisher: Wolters Kluwer Health, on behalf of the American Society of Nephrology Country of Publication: United States NLM ID: 9013836 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1533-3450 (Electronic) Linking ISSN: 10466673 NLM ISO Abbreviation: J Am Soc Nephrol Subsets: MEDLINE; In Process

Profiling of insulin-resistant kidney models and human biopsies reveals common and cell-type-specific mechanisms underpinning Diabetic Kidney Disease.

Authors: Lay AC Tran VDT Nair V et al.

Corporate Authors: Lay AC Tran VDT Nair V et al.

Source: Nature communications [Nat Commun] 2024 Nov 19; Vol. 15 (1), pp. 10018. Date of Electronic Publication: 2024 Nov 19.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

A Novel Role of Hyaluronan and Its Membrane Receptors, CD44 and RHAMM, in Obesity-Related Kidney Pathology.

Authors: Qi B Musale V Weng X et al.

Source: Biomolecules [Biomolecules] 2025 Nov 14; Vol. 15 (11). Date of Electronic Publication: 2025 Nov 14.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101596414 Publication Model: Electronic Cited Medium: Internet ISSN: 2218-273X (Electronic) Linking ISSN: 2218273X NLM ISO Abbreviation: Biomolecules Subsets: MEDLINE

Genetic imputation of kidney transcriptome, proteome and multi-omics illuminates new blood pressure and hypertension targets.

Authors: Xu X Khunsriraksakul C Eales JM et al.

Corporate Authors: Xu X Khunsriraksakul C Eales JM et al.

Source: Nature communications [Nat Commun] 2024 Mar 19; Vol. 15 (1), pp. 2359. Date of Electronic Publication: 2024 Mar 19.

Publication Type: Journal Article

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

Podocyte Bioenergetics in the Development of Diabetic Nephropathy: The Role of Mitochondria.

Authors: Audzeyenka I Bierżyńska A Lay AC

Source: Endocrinology [Endocrinology] 2022 Jan 01; Vol. 163 (1).

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Review

Journal Info: Publisher: Oxford University Press Country of Publication: United States NLM ID: 0375040 Publication Model: Print Cited Medium: Internet ISSN: 1945-7170 (Electronic) Linking ISSN: 00137227 NLM ISO Abbreviation: Endocrinology Subsets: MEDLINE

Does FFAR4 Agonism have Therapeutic Potential in Cardiometabolic Disease?

Authors: Lay AC; Bristol Renal, Bristol Medical School, University of Bristol, Bristol, BS1 3NY, UK.

Source: Endocrinology [Endocrinology] 2021 Oct 01; Vol. 162 (10).

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Comment

Journal Info: Publisher: Oxford University Press Country of Publication: United States NLM ID: 0375040 Publication Model: Print Cited Medium: Internet ISSN: 1945-7170 (Electronic) Linking ISSN: 00137227 NLM ISO Abbreviation: Endocrinology Subsets: MEDLINE

Contrasting consequences of podocyte insulin-like growth factor 1 receptor inhibition.

Authors: Hurcombe JA Barrington F Marchetti M et al.

Source: IScience [iScience] 2024 Apr 16; Vol. 27 (5), pp. 109749. Date of Electronic Publication: 2024 Apr 16 (Print Publication: 2024).

Publication Type: Journal Article

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101724038 Publication Model: eCollection Cited Medium: Internet ISSN: 2589-0042 (Electronic) Linking ISSN: 25890042 NLM ISO Abbreviation: iScience Subsets: PubMed not MEDLINE

IGFBP-1 expression is reduced in human type 2 diabetic glomeruli and modulates β1-integrin/FAK signalling in human podocytes.

Authors: Lay AC Hale LJ Stowell-Connolly H et al.

Source: Diabetologia [Diabetologia] 2021 Jul; Vol. 64 (7), pp. 1690-1702. Date of Electronic Publication: 2021 Mar 24.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0006777 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0428 (Electronic) Linking ISSN: 0012186X NLM ISO Abbreviation: Diabetologia Subsets: MEDLINE

Shiga toxin targets the podocyte causing hemolytic uremic syndrome through endothelial complement activation.

Authors: Bowen EE Hurcombe JA Barrington F et al.

Source: Med (New York, N.Y.) [Med] 2023 Nov 10; Vol. 4 (11), pp. 761-777.e8. Date of Electronic Publication: 2023 Oct 19.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101769215 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2666-6340 (Electronic) Linking ISSN: 26666340 NLM ISO Abbreviation: Med Subsets: MEDLINE

Podocyte GSK3 is an evolutionarily conserved critical regulator of kidney function.

Authors: Hurcombe JA Hartley P Lay AC et al.

Source: Nature communications [Nat Commun] 2019 Jan 24; Vol. 10 (1), pp. 403. Date of Electronic Publication: 2019 Jan 24.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

The Evolving Importance of Insulin Signaling in Podocyte Health and Disease.

Authors: Lay AC Coward RJM

Source: Frontiers in endocrinology [Front Endocrinol (Lausanne)] 2018 Nov 21; Vol. 9, pp. 693. Date of Electronic Publication: 2018 Nov 21 (Print Publication: 2018).

Publication Type: Journal Article; Review

Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101555782 Publication Model: eCollection Cited Medium: Print ISSN: 1664-2392 (Print) Linking ISSN: 16642392 NLM ISO Abbreviation: Front Endocrinol (Lausanne) Subsets: PubMed not MEDLINE

An in vitro approach to understand contribution of kidney cells to human urinary extracellular vesicles.

Authors: Barreiro K Lay AC Leparc G et al.

Source: Journal of extracellular vesicles [J Extracell Vesicles] 2023 Feb; Vol. 12 (2), pp. e12304.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 101610479 Publication Model: Print Cited Medium: Internet ISSN: 2001-3078 (Electronic) Linking ISSN: 20013078 NLM ISO Abbreviation: J Extracell Vesicles Subsets: MEDLINE

Prolonged exposure of mouse and human podocytes to insulin induces insulin resistance through lysosomal and proteasomal degradation of the insulin receptor.

Authors: Lay AC Hurcombe JA Betin VMS et al.

Source: Diabetologia [Diabetologia] 2017 Nov; Vol. 60 (11), pp. 2299-2311. Date of Electronic Publication: 2017 Aug 29.

Publication Type: Journal Article

Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0006777 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0428 (Electronic) Linking ISSN: 0012186X NLM ISO Abbreviation: Diabetologia Subsets: MEDLINE

Reduced Glomerular Filtration in Diabetes Is Attributable to Loss of Density and Increased Resistance of Glomerular Endothelial Cell Fenestrations.

Authors: Finch NC Fawaz SS Neal CR et al.

Source: Journal of the American Society of Nephrology : JASN [J Am Soc Nephrol] 2022 Jun; Vol. 33 (6), pp. 1120-1136. Date of Electronic Publication: 2022 Mar 15.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Wolters Kluwer Health, on behalf of the American Society of Nephrology Country of Publication: United States NLM ID: 9013836 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1533-3450 (Electronic) Linking ISSN: 10466673 NLM ISO Abbreviation: J Am Soc Nephrol Subsets: MEDLINE

The EWAS Catalog: a database of epigenome-wide association studies.

Authors: Battram T Yousefi P Crawford G et al.

Source: Wellcome open research [Wellcome Open Res] 2022 May 31; Vol. 7, pp. 41. Date of Electronic Publication: 2022 May 31 (Print Publication: 2022).

Publication Type: Journal Article

Journal Info: Publisher: Wellcome Trust Country of Publication: England NLM ID: 101696457 Publication Model: eCollection Cited Medium: Print ISSN: 2398-502X (Print) Linking ISSN: 2398502X NLM ISO Abbreviation: Wellcome Open Res Subsets: PubMed not MEDLINE

An information theoretic approach to insulin sensing by human kidney podocytes.

Authors: Pope RJ Garner KL Voliotis M et al.

Source: Molecular and cellular endocrinology [Mol Cell Endocrinol] 2020 Dec 01; Vol. 518, pp. 110976. Date of Electronic Publication: 2020 Aug 01.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: North Holland Publishing Country of Publication: Ireland NLM ID: 7500844 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-8057 (Electronic) Linking ISSN: 03037207 NLM ISO Abbreviation: Mol Cell Endocrinol Subsets: MEDLINE

A role for NPY-NPY2R signaling in albuminuric kidney disease.

Authors: Lay AC Barrington AF Hurcombe JA et al.

Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Jul 07; Vol. 117 (27), pp. 15862-15873. Date of Electronic Publication: 2020 Jun 19.

Publication Type: Journal Article; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

Blocking matrix metalloproteinase-mediated syndecan-4 shedding restores the endothelial glycocalyx and glomerular filtration barrier function in early diabetic kidney disease.

Authors: Ramnath RD Butler MJ Newman G et al.

Source: Kidney international [Kidney Int] 2020 May; Vol. 97 (5), pp. 951-965. Date of Electronic Publication: 2019 Nov 02.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 0323470 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1523-1755 (Electronic) Linking ISSN: 00852538 NLM ISO Abbreviation: Kidney Int Subsets: MEDLINE

An In Vitro Method to Analyze Glucose Uptake in Podocytes.

Authors: Lay AC Coward RJ

Source: Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2020; Vol. 2067, pp. 139-143.

Publication Type: Journal Article

Journal Info: Publisher: Humana Press Country of Publication: United States NLM ID: 9214969 Publication Model: Print Cited Medium: Internet ISSN: 1940-6029 (Electronic) Linking ISSN: 10643745 NLM ISO Abbreviation: Methods Mol Biol Subsets: MEDLINE

TRPC6 Binds to and Activates Calpain, Independent of Its Channel Activity, and Regulates Podocyte Cytoskeleton, Cell Adhesion, and Motility.

Authors: Farmer LK Rollason R Whitcomb DJ et al.

Source: Journal of the American Society of Nephrology : JASN [J Am Soc Nephrol] 2019 Oct; Vol. 30 (10), pp. 1910-1924. Date of Electronic Publication: 2019 Aug 15.

Publication Type: Journal Article; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Wolters Kluwer Health, on behalf of the American Society of Nephrology Country of Publication: United States NLM ID: 9013836 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1533-3450 (Electronic) Linking ISSN: 10466673 NLM ISO Abbreviation: J Am Soc Nephrol Subsets: MEDLINE