Search Results - "Lessard CB"

Progressive Supranuclear Palsy PERK Haplotype B Selectively Translates DLX1 Promoting Tau Toxicity.

Authors: Lessard CB Rubio Rubio D Tolton S et al.

Source: The Journal of neuroscience : the official journal of the Society for Neuroscience [J Neurosci] 2026 Apr 01; Vol. 46 (13). Date of Electronic Publication: 2026 Apr 01.

Publication Type: Journal Article

Journal Info: Publisher: Society for Neuroscience Country of Publication: United States NLM ID: 8102140 Publication Model: Electronic Cited Medium: Internet ISSN: 1529-2401 (Electronic) Linking ISSN: 02706474 NLM ISO Abbreviation: J Neurosci Subsets: MEDLINE

Cerebrospinal fluid markers link to synaptic plasticity responses and Alzheimer's disease genetic pathways.

Authors: Kirsebom, Bjørn-Eivind Nilsson, Johanna Vromen, Ellen et al.

Source: Molecular Neurodegeneration. 10/13/2025, Vol. 20 Issue 1, p1-21. 21p.

PET imaging of TREM2 in amyloid-beta induced neuroinflammation.

Authors: Dahlén, Amelia D Roshanbin, Sahar Aguilar, Ximena et al.

Source: European Journal of Nuclear Medicine & Molecular Imaging. Sep2025, Vol. 52 Issue 11, p4320-4333. 14p.

Role Shift of Glial Cells from Physiology to Pathology in Alzheimer's Disease: The Regulatory Impact of Exercise.

Authors: Liu R Deng Q Gong L et al.

Source: Neuroscience bulletin [Neurosci Bull] 2026 Jul; Vol. 42 (7), pp. 1617-1649. Date of Electronic Publication: 2026 Feb 16.

Publication Type: Journal Article; Review

Journal Info: Publisher: Springer Singapore Country of Publication: Singapore NLM ID: 101256850 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1995-8218 (Electronic) Linking ISSN: 19958218 NLM ISO Abbreviation: Neurosci Bull Subsets: MEDLINE

Antagonizing Il10 and Il4 signaling via intracerebral decoy receptor expression attenuates Aβ accumulation.

Authors: Koller, Emily J. McFarland, Karen N. Angelle, Conner et al.

Source: Acta Neuropathologica Communications. 3/7/2025, Vol. 13 Issue 1, p1-18. 18p.

The protective PLCγ2-P522R variant mitigates Alzheimer's disease-associated pathologies by enhancing beneficial microglial functions.

Authors: Takalo, Mari Jeskanen, Heli Rolova, Taisia et al.

Source: Journal of Neuroinflammation. 3/5/2025, Vol. 22 Issue 1, p1-30. 30p.

TREM2 in neurodegeneration and diseases.

Authors: Abdulkhaliq AA Alasiri G Kim B et al.

Source: Molecular psychiatry [Mol Psychiatry] 2026 Jul; Vol. 31 (7), pp. 3978-3986. Date of Electronic Publication: 2026 Mar 06.

Publication Type: Journal Article; Review

Journal Info: Publisher: Nature Publishing Group Specialist Journals Country of Publication: England NLM ID: 9607835 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5578 (Electronic) Linking ISSN: 13594184 NLM ISO Abbreviation: Mol Psychiatry Subsets: MEDLINE

Biobank-based genetic characterization of neurodegenerative diseases and idiopathic normal pressure hydrocephalus: insights and lessons learned from FinnGen.

Authors: Heikkinen S Julkunen V Martiskainen H et al.

Source: Molecular psychiatry [Mol Psychiatry] 2026 Jun 12. Date of Electronic Publication: 2026 Jun 12.

Publication Type: Journal Article; Review

Journal Info: Publisher: Nature Publishing Group Specialist Journals Country of Publication: England NLM ID: 9607835 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5578 (Electronic) Linking ISSN: 13594184 NLM ISO Abbreviation: Mol Psychiatry Subsets: MEDLINE

Alzheimer's disease PSEN-2 N141I mutation reveals altered and shear-sensitive brain endothelial cell-like phenotype in human iPSC-derived models.

Authors: Takeuchi, Lily E. Lam, Jennifer Simmons, Craig A.

Source: Acta Neuropathologica Communications. 11/11/2025, Vol. 13 Issue 1, p1-16. 16p.

Biophysical mapping of TREM2-ligand interactions reveals shared surfaces for engagement of multiple Alzheimer's disease ligands.

Authors: Greven, Jessica A. Wydra, Joshua R. Greer, Rory A. et al.

Source: Molecular Neurodegeneration. 1/9/2025, Vol. 20 Issue 1, p1-20. 20p.

Notch Signaling as a Way to Control the Endothelial-To-Mesenchymal Transition.

Authors: Evensen, D. Smirnova, D. Belyaeva, A. et al.

Source: Journal of Evolutionary Biochemistry & Physiology. Jan2025, Vol. 61 Issue 1, p313-327. 15p.

Alzheimer's disease-associated protective variant Plcg2-P522R modulates peripheral macrophage function in a sex-dimorphic manner.

Authors: Staley, Hannah A. Jernigan, Janna E. Bolen, MacKenzie L. et al.

Source: Journal of Neuroinflammation. 11/1/2024, Vol. 21 Issue 1, p1-16. 16p.

Efficacy and safety of blood derivatives therapy in Alzheimer's disease: a systematic review and meta-analysis.

Authors: Fei, Zhangcheng Pan, Bo Pei, Renjun et al.

Source: Systematic Reviews. 11/29/2022, Vol. 11 Issue 1, p1-11. 11p.

Roles of TREM2 in Alzheimer's disease.

Authors: Qi, Xiaoshan Zhu, Kedong Ke, Wei et al.

Source: Translational Neurodegeneration. 10/31/2025, Vol. 14 Issue 1, p1-32. 32p.

A novel micellular fluorogenic substrate for quantitating the activity of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma (PLCγ) enzymes.

Authors: Visvanathan, Ramya Utsuki, Tadanobu Beck, Daniel E. et al.

Source: PLoS ONE. 3/29/2024, Vol. 19 Issue 3, p1-18. 18p.

Altered amyloid-β structure markedly reduces gliosis in the brain of mice harboring the Uppsala APP deletion.

Authors: Pagnon de la Vega, María Syvänen, Stina Giedraitis, Vilmantas et al.

Source: Acta Neuropathologica Communications. 2/5/2024, Vol. 12, p1-16. 16p.

Convergence of sepsis-associated encephalopathy pathogenesis onto microglia.

Authors: Xiao, Dan Wang, Xiao Liang, Wanting et al.

Source: Journal of Translational Medicine. 6/3/2025, Vol. 23 Issue 1, p1-19. 19p.

Proof-of-concept recall-by-genotype study of extremely low and high Alzheimer's polygenic risk reveals autobiographical deficits and cingulate cortex correlates.

Authors: Lancaster, Thomas Creese, Byron Escott-Price, Valentina et al.

Source: Alzheimer's Research & Therapy. 12/12/2023, Vol. 15 Issue 1, p1-10. 10p.

Identification of the minimal active soluble TREM2 sequence for modulating microglial phenotypes and amyloid pathology.

Authors: Sheng, Xuan Yao, Yunling Huang, Ruizhi et al.

Source: Journal of Neuroinflammation. 12/10/2021, Vol. 18 Issue 1, p1-12. 12p.

TREM2 and sTREM2 in Alzheimer's disease: from mechanisms to therapies.

Authors: Zhang, Lianshuai Xiang, Xianyuan Li, Yahui et al.

Source: Molecular Neurodegeneration. 4/17/2025, Vol. 20 Issue 1, p1-19. 19p.