Search Results - "Liebman SW"

Deletion of the Saccharomyces cerevisiae RACK1 homolog, ASC1, enhances autophagy which mitigates TDP-43 toxicity.

Authors: Park SK Park S Liebman SW

Source: Genetics [Genetics] 2026 Apr 04; Vol. 232 (4).

Publication Type: Journal Article; Research Support, N.I.H., Extramural

Journal Info: Publisher: Oxford University Press Country of Publication: United States NLM ID: 0374636 Publication Model: Print Cited Medium: Internet ISSN: 1943-2631 (Electronic) Linking ISSN: 00166731 NLM ISO Abbreviation: Genetics Subsets: MEDLINE

Interactions between non-prion and prion domains of Rnq1 direct formation of amyloid vs liquid-like aggregates and create transmission barriers.

Authors: Park S Maldonado DM Kadnar ML et al.

Source: BioRxiv : the preprint server for biology [bioRxiv] 2026 Mar 17. Date of Electronic Publication: 2026 Mar 17.

Publication Type: Journal Article; Preprint

Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

Deletion of the Saccharomyces cerevisiae RACK1 homolog, ASC1 , enhances autophagy which mitigates TDP-43 toxicity.

Authors: Park SK Park S Liebman SW

Source: BioRxiv : the preprint server for biology [bioRxiv] 2025 Sep 05. Date of Electronic Publication: 2025 Sep 05.

Publication Type: Journal Article; Preprint

Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

An adenine model of inborn metabolism errors alters TDP-43 aggregation and reduces its toxicity in yeast revealing insights into protein misfolding diseases.

Authors: Park S Park SK Blair P et al.

Source: Microbial cell (Graz, Austria) [Microb Cell] 2025 May 22; Vol. 12, pp. 119-130. Date of Electronic Publication: 2025 May 22 (Print Publication: 2025).

Publication Type: Journal Article

Journal Info: Publisher: Shared Science Publishers OG Country of Publication: Austria NLM ID: 101632887 Publication Model: eCollection Cited Medium: Print ISSN: 2311-2638 (Print) Linking ISSN: 23112638 NLM ISO Abbreviation: Microb Cell Subsets: PubMed not MEDLINE

A model of inborn metabolism errors associated with adenine amyloid-like fiber formation reduces TDP-43 aggregation and toxicity in yeast.

Authors: Park S Park SK Liebman SW

Source: BioRxiv : the preprint server for biology [bioRxiv] 2024 Dec 07. Date of Electronic Publication: 2024 Dec 07.

Publication Type: Journal Article; Preprint

Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

A lifesaving revolution delayed.

Authors: Liebman SW; Department of Pharmacology, University of Nevada, Reno, Reno, NV, USA. SLiebman@unr.edu.

Source: Nature genetics [Nat Genet] 2024 Dec; Vol. 56 (12), pp. 2579.

Publication Type: Journal Article

Journal Info: Publisher: Nature Pub. Co Country of Publication: United States NLM ID: 9216904 Publication Model: Print Cited Medium: Internet ISSN: 1546-1718 (Electronic) Linking ISSN: 10614036 NLM ISO Abbreviation: Nat Genet Subsets: MEDLINE; In Process

Long non-coding RNA NEAT1_1 ameliorates TDP-43 toxicity in in vivo models of TDP-43 proteinopathy.

Authors: Matsukawa K Kukharsky MS Park SK et al.

Source: RNA biology [RNA Biol] 2021 Nov; Vol. 18 (11), pp. 1546-1554. Date of Electronic Publication: 2021 Jan 11.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101235328 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1555-8584 (Electronic) Linking ISSN: 15476286 NLM ISO Abbreviation: RNA Biol Subsets: MEDLINE

Expression of Wild-Type and Mutant Human TDP-43 in Yeast Inhibits TOROID (TORC1 Organized in Inhibited Domain) Formation and Autophagy Proportionally to the Levels of TDP-43 Toxicity.

Authors: Park S Park SK Liebman SW

Source: International journal of molecular sciences [Int J Mol Sci] 2024 Jun 06; Vol. 25 (11). Date of Electronic Publication: 2024 Jun 06.

Publication Type: Journal Article

Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

Exploring Fundamentals of Prion Biology Using Natural Yeast Prions and Mammalian PrP.

Authors: Derkatch IL Liebman SW

Source: Viruses [Viruses] 2024 May 16; Vol. 16 (5). Date of Electronic Publication: 2024 May 16.

Publication Type: Editorial; Introductory Journal Article

Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101509722 Publication Model: Electronic Cited Medium: Internet ISSN: 1999-4915 (Electronic) Linking ISSN: 19994915 NLM ISO Abbreviation: Viruses Subsets: MEDLINE

Calcium-responsive transactivator (CREST) toxicity is rescued by loss of PBP1/ATXN2 function in a novel yeast proteinopathy model and in transgenic flies.

Authors: Park S Park SK Watanabe N et al.

Source: PLoS genetics [PLoS Genet] 2019 Aug 07; Vol. 15 (8), pp. e1008308. Date of Electronic Publication: 2019 Aug 07 (Print Publication: 2019).

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101239074 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7404 (Electronic) Linking ISSN: 15537390 NLM ISO Abbreviation: PLoS Genet Subsets: MEDLINE

Comment on Billant et al. p53, A Victim of the Prion Fashion. Cancers 2021, 13, 269.

Authors: Liebman SW Derkatch IL Park S et al.

Source: Cancers [Cancers (Basel)] 2023 Jan 03; Vol. 15 (1). Date of Electronic Publication: 2023 Jan 03.

Publication Type: Journal Article

Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101526829 Publication Model: Electronic Cited Medium: Print ISSN: 2072-6694 (Print) Linking ISSN: 20726694 NLM ISO Abbreviation: Cancers (Basel) Subsets: PubMed not MEDLINE

TDP-43 Toxicity in Yeast Is Associated with a Reduction in Autophagy, and Deletions of TIP41 and PBP1 Counteract These Effects.

Authors: Park SK Park S Liebman SW

Source: Viruses [Viruses] 2022 Oct 15; Vol. 14 (10). Date of Electronic Publication: 2022 Oct 15.

Publication Type: Journal Article; Research Support, N.I.H., Extramural

Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101509722 Publication Model: Electronic Cited Medium: Internet ISSN: 1999-4915 (Electronic) Linking ISSN: 19994915 NLM ISO Abbreviation: Viruses Subsets: MEDLINE

Overexpression of a conserved HSP40 chaperone reduces toxicity of several neurodegenerative disease proteins.

Authors: Park SK Arslan F Kanneganti V et al.

Source: Prion [Prion] 2018 Jan 02; Vol. 12 (1), pp. 16-22. Date of Electronic Publication: 2018 Jan 31.

Publication Type: Journal Article; Research Support, N.I.H., Extramural

Journal Info: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101472305 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1933-690X (Electronic) Linking ISSN: 19336896 NLM ISO Abbreviation: Prion Subsets: MEDLINE

Overexpression of the essential Sis1 chaperone reduces TDP-43 effects on toxicity and proteolysis.

Authors: Park SK Hong JY Arslan F et al.

Source: PLoS genetics [PLoS Genet] 2017 May 22; Vol. 13 (5), pp. e1006805. Date of Electronic Publication: 2017 May 22 (Print Publication: 2017).

Publication Type: Journal Article

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101239074 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7404 (Electronic) Linking ISSN: 15537390 NLM ISO Abbreviation: PLoS Genet Subsets: MEDLINE

A founder mutation in FLNC is likely a major cause of idiopathic dilated cardiomyopathy in Ashkenazi Jews.

Authors: Liebman SW Palaganas H Kobany H

Source: International journal of cardiology [Int J Cardiol] 2021 Jan 15; Vol. 323, pp. 124. Date of Electronic Publication: 2020 Aug 15.

Publication Type: Letter; Comment

Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8200291 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1874-1754 (Electronic) Linking ISSN: 01675273 NLM ISO Abbreviation: Int J Cardiol Subsets: MEDLINE

Tumor suppressor protein p53 expressed in yeast can remain diffuse, form a prion, or form unstable liquid-like droplets.

Authors: Park SK Park S Pentek C et al.

Source: IScience [iScience] 2020 Dec 29; Vol. 24 (1), pp. 102000. Date of Electronic Publication: 2020 Dec 29 (Print Publication: 2021).

Publication Type: Journal Article

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101724038 Publication Model: eCollection Cited Medium: Internet ISSN: 2589-0042 (Electronic) Linking ISSN: 25890042 NLM ISO Abbreviation: iScience Subsets: PubMed not MEDLINE

Heterologous aggregates promote de novo prion appearance via more than one mechanism.

Authors: Arslan F Hong JY Kanneganti V et al.

Source: PLoS genetics [PLoS Genet] 2015 Jan 08; Vol. 11 (1), pp. e1004814. Date of Electronic Publication: 2015 Jan 08 (Print Publication: 2015).

Publication Type: Journal Article; Research Support, N.I.H., Extramural

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101239074 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7404 (Electronic) Linking ISSN: 15537390 NLM ISO Abbreviation: PLoS Genet Subsets: MEDLINE

Prion-promoted phosphorylation of heterologous amyloid is coupled with ubiquitin-proteasome system inhibition and toxicity.

Authors: Yang Z Stone DE Liebman SW

Source: Molecular microbiology [Mol Microbiol] 2014 Sep; Vol. 93 (5), pp. 1043-56. Date of Electronic Publication: 2014 Aug 05.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.

Journal Info: Publisher: Blackwell Scientific Publications Country of Publication: England NLM ID: 8712028 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2958 (Electronic) Linking ISSN: 0950382X NLM ISO Abbreviation: Mol Microbiol Subsets: MEDLINE

Retrospective. Fred Sherman (1932-2013).

Authors: Liebman SW Haber JE

Source: Science (New York, N.Y.) [Science] 2013 Nov 29; Vol. 342 (6162), pp. 1059.

Publication Type: Biography; Historical Article; Journal Article; Portrait

Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE

The story of stolen chaperones: how overexpression of Q/N proteins cures yeast prions.

Authors: Derkatch IL Liebman SW

Source: Prion [Prion] 2013 Jul-Aug; Vol. 7 (4), pp. 294-300. Date of Electronic Publication: 2013 Aug 07.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Comment

Journal Info: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101472305 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1933-690X (Electronic) Linking ISSN: 19336896 NLM ISO Abbreviation: Prion Subsets: MEDLINE