Search Results - "Lin, Simeng"

Whole Blood DNA Methylation Changes Are Associated with Anti-TNF Drug Concentration in Patients with Crohn's Disease.

Authors: Lin, Simeng Hannon, Eilis Reppell, Mark et al.

Source: Journal of Crohn's & Colitis. Aug2024, Vol. 18 Issue 8, p1190-1201. 12p.

Implications for sequencing of biologic therapy and choice of second anti‐TNF in patients with inflammatory bowel disease: results from the IMmunogenicity to Second Anti‐TNF therapy (IMSAT) therapeutic drug monitoring study.

Authors: Chanchlani, Neil Lin, Simeng Auth, Marcus K. et al.

Source: Alimentary Pharmacology & Therapeutics. Oct2022, Vol. 56 Issue 8, p1250-1263. 14p. 1 Diagram, 2 Charts, 4 Graphs.

Understanding anti‐TNF treatment failure: does serum triiodothyronine‐to‐thyroxine (T3/T4) ratio predict therapeutic outcome to anti‐TNF therapies in biologic‐naïve patients with active luminal Crohn's disease?

Authors: Lin, Simeng Chanchlani, Neil Carbery, Isabel et al.

Source: Alimentary Pharmacology & Therapeutics. Sep2022, Vol. 56 Issue 5, p783-793. 11p. 1 Diagram, 3 Charts, 2 Graphs.

Adalimumab and Infliximab Impair SARS-CoV-2 Antibody Responses: Results from a Therapeutic Drug Monitoring Study in 11 422 Biologic-Treated Patients.

Authors: Chanchlani, Neil Lin, Simeng Chee, Desmond et al.

Source: Journal of Crohn's & Colitis. Mar2022, Vol. 16 Issue 3, p389-397. 9p.

Clinical Features and Genetic Risk of Demyelination Following Anti-TNF Treatment.

Authors: Lin, Simeng Green, Harry D Hendy, Peter et al.

Source: Journal of Crohn's & Colitis. Dec2020, Vol. 14 Issue 12, p1653-1661. 9p.

Quality improvement project identifies factors associated with delay in IBD diagnosis.

Authors: Walker, Gareth J. Lin, Simeng Chanchlani, Neil et al.

Source: Alimentary Pharmacology & Therapeutics. Aug2020, Vol. 52 Issue 3, p471-480. 10p. 1 Diagram, 5 Charts, 1 Graph.

Clinical Utility and Cost‐Effectiveness of Pretreatment NUDT15 Pharmacogenetic Testing to Prevent Thiopurine‐Induced Myelosuppression: A Genotype‐First Reverse Phenotyping Cohort Study Within the UK NIHR Inflammatory Bowel Disease Bioresource

Authors: Roberts, Christopher Peters, Jaime Sazonvos, Aleksejs et al.

Source: Alimentary Pharmacology & Therapeutics. Sep2025, Vol. 62 Issue 6, p630-645. 16p.

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Baseline TREM-1 Whole Blood Gene Expression Does Not Predict Response to Adalimumab Treatment in Patients with Ulcerative Colitis or Crohn's Disease in the SERENE Studies.

Authors: Verstockt, Bram Pivorunas, Valerie Mahi, Naim Al et al.

Source: Journal of Crohn's & Colitis. Apr2024, Vol. 18 Issue 4, p493-505. 13p.

Baseline Expression of Immune Gene Modules in Blood is Associated With Primary Response to Anti-TNF Therapy in Crohn's Disease Patients.

Authors: Bai, Benjamin Y H Reppell, Mark Smaoui, Nizar et al.

Source: Journal of Crohn's & Colitis. Mar2024, Vol. 18 Issue 3, p431-445. 15p.

Anti-TNF Biologicals Enhance the Anti-Inflammatory Properties of IgG N-Glycome in Crohn's Disease.

Authors: Hanić, Maja Vučković, Frano Deriš, Helena et al.

Source: Biomolecules (2218-273X). Jun2023, Vol. 13 Issue 6, p954. 13p.

Patient-led Remote IntraCapillary pharmacoKinetic Sampling (fingerPRICKS) for Therapeutic Drug Monitoring in patients with Inflammatory Bowel Disease.

Authors: Chee, Desmond Nice, Rachel Hamilton, Ben et al.

Source: Journal of Crohn's & Colitis. Feb2022, Vol. 16 Issue 2, p190-198. 9p.

Root‐cause analyses of missed opportunities for the diagnosis of colorectal cancer in patients with inflammatory bowel disease.

Authors: Gordon, Claire Chee, Desmond Hamilton, Ben et al.

Source: Alimentary Pharmacology & Therapeutics. Jan2021, Vol. 53 Issue 2, p291-301. 11p. 1 Diagram, 3 Charts, 2 Graphs.

Understanding Anti-TNF Treatment Failure: Pre-Existing Antidrug Antibodies Are Common but Do Not Neutralize Drug Activity In Vitro or Influence Clinical Response to Infliximab or Adalimumab in Patients with Crohn Disease.

Authors: Nice R Lin S Chanchlani N et al.

Source: The journal of applied laboratory medicine [J Appl Lab Med] 2025 Nov 04; Vol. 10 (6), pp. 1580-1592.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 101693884 Publication Model: Print Cited Medium: Print ISSN: 2576-9456 (Print) Linking ISSN: 24757241 NLM ISO Abbreviation: J Appl Lab Med Subsets: MEDLINE

Pretreatment Vitamin D Concentrations Do Not Predict Therapeutic Outcome to Anti-TNF Therapies in Biologic-Naïve Patients With Active Luminal Crohn's Disease.

Authors: Chanchlani N Lin S Smith R et al.

Source: Crohn's & colitis 360 [Crohns Colitis 360] 2023 May 15; Vol. 5 (3), pp. otad026. Date of Electronic Publication: 2023 May 15 (Print Publication: 2023).

Publication Type: Journal Article

Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 101752188 Publication Model: eCollection Cited Medium: Internet ISSN: 2631-827X (Electronic) Linking ISSN: 2631827X NLM ISO Abbreviation: Crohns Colitis 360 Subsets: PubMed not MEDLINE

Naive pluripotent stem cell-based models capture FGF-dependent human hypoblast lineage specification.

Authors: Dattani A Corujo-Simon E Radley A et al.

Source: Cell stem cell [Cell Stem Cell] 2024 Jul 05; Vol. 31 (7), pp. 1058-1071.e5. Date of Electronic Publication: 2024 May 31.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101311472 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1875-9777 (Electronic) Linking ISSN: 18759777 NLM ISO Abbreviation: Cell Stem Cell Subsets: MEDLINE

Mechanisms and management of loss of response to anti-TNF therapy for patients with Crohn's disease: 3-year data from the prospective, multicentre PANTS cohort study.

Authors: Chanchlani N Lin S Bewshea C et al.

Corporate Authors: Chanchlani N Lin S Bewshea C et al.

Source: The lancet. Gastroenterology & hepatology [Lancet Gastroenterol Hepatol] 2024 Jun; Vol. 9 (6), pp. 521-538. Date of Electronic Publication: 2024 Apr 16.

Publication Type: Journal Article; Multicenter Study; Observational Study; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Elsevier B.V Country of Publication: Netherlands NLM ID: 101690683 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2468-1253 (Electronic) NLM ISO Abbreviation: Lancet Gastroenterol Hepatol Subsets: MEDLINE

The gut microbiota and metabolome are associated with diminished COVID-19 vaccine-induced antibody responses in immunosuppressed inflammatory bowel disease patients.

Authors: Alexander JL Mullish BH Danckert NP et al.

Source: EBioMedicine [EBioMedicine] 2023 Feb; Vol. 88, pp. 104430. Date of Electronic Publication: 2023 Jan 10.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier B.V Country of Publication: Netherlands NLM ID: 101647039 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2352-3964 (Electronic) Linking ISSN: 23523964 NLM ISO Abbreviation: EBioMedicine Subsets: MEDLINE

Vaccine escape, increased breakthrough and reinfection in infliximab-treated patients with IBD during the Omicron wave of the SARS-CoV-2 pandemic.

Authors: Kennedy NA Janjua M Chanchlani N et al.

Source: Gut [Gut] 2023 Feb; Vol. 72 (2), pp. 295-305. Date of Electronic Publication: 2022 Jul 28.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: British Medical Assn Country of Publication: England NLM ID: 2985108R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1468-3288 (Electronic) Linking ISSN: 00175749 NLM ISO Abbreviation: Gut Subsets: MEDLINE

Neutralising antibody potency against SARS-CoV-2 wild-type and omicron BA.1 and BA.4/5 variants in patients with inflammatory bowel disease treated with infliximab and vedolizumab after three doses of COVID-19 vaccine (CLARITY IBD): an analysis of a prospective multicentre cohort study.

Authors: Liu Z Le K Zhou X et al.

Corporate Authors: Liu Z Le K Zhou X et al.

Source: The lancet. Gastroenterology & hepatology [Lancet Gastroenterol Hepatol] 2023 Feb; Vol. 8 (2), pp. 145-156. Date of Electronic Publication: 2022 Dec 05.

Publication Type: Observational Study; Multicenter Study; Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Elsevier B.V Country of Publication: Netherlands NLM ID: 101690683 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2468-1253 (Electronic) NLM ISO Abbreviation: Lancet Gastroenterol Hepatol Subsets: MEDLINE