Search Results - "Lorente JS"

Global glucagon-like peptide-2 receptor activation linked to increased obesity risk in the UK Biobank.

Authors: Gerlach PA Gadgaard S Madsen JS et al.

Source: Metabolism: clinical and experimental [Metabolism] 2026 Apr; Vol. 177, pp. 156489. Date of Electronic Publication: 2026 Jan 08.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Inc Country of Publication: United States NLM ID: 0375267 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-8600 (Electronic) Linking ISSN: 00260495 NLM ISO Abbreviation: Metabolism Subsets: MEDLINE

An online GPCR drug discovery resource.

Authors: Caroli J Andreassen SN Lorente JS et al.

Source: Npj drug discovery [NPJ Drug Discov] 2025 Jul 23; Vol. 2 (1). Date of Electronic Publication: 2025 Jul 23.

Publication Type: Journal Article

Journal Info: Publisher: Nature Portfolio Country of Publication: England NLM ID: 9918993695206676 Publication Model: Electronic Cited Medium: Internet ISSN: 3005-1452 (Electronic) Linking ISSN: 30051452 NLM ISO Abbreviation: NPJ Drug Discov Subsets: PubMed not MEDLINE

GPCR drug discovery: new agents, targets and indications.

Authors: Lorente JS Sokolov AV Ferguson G et al.

Source: Nature reviews. Drug discovery [Nat Rev Drug Discov] 2025 Jun; Vol. 24 (6), pp. 458-479. Date of Electronic Publication: 2025 Mar 03.

Publication Type: Journal Article; Review; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101124171 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1474-1784 (Electronic) Linking ISSN: 14741776 NLM ISO Abbreviation: Nat Rev Drug Discov Subsets: MEDLINE

Drug repurposing for Alzheimer's disease using a graph-of-thoughts based large language model to infer drug-disease relationships in a comprehensive knowledge graph.

Authors: Wang, Zhiping Paul Li, Xi Matsumoto, Nicholas et al.

Source: BioData Mining. 8/5/2025, Vol. 18 Issue 1, p1-19. 19p.

Characterization of ADGRG6 as a potential molecular oncotarget of pancreatic cancer.

Authors: Gu QH Zhu XR Jiang JZ et al.

Source: Cell death & disease [Cell Death Dis] 2026 May 06; Vol. 17 (1). Date of Electronic Publication: 2026 May 06.

Publication Type: Journal Article

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-4889 (Electronic) NLM ISO Abbreviation: Cell Death Dis Subsets: MEDLINE

Resolution Pharmacology Targeting the Melanocortin System.

Authors: Day NJ Davan-Wetton CSA Khodeneva N et al.

Source: Current topics in microbiology and immunology [Curr Top Microbiol Immunol] 2026 May 19. Date of Electronic Publication: 2026 May 19.

Publication Type: Journal Article

Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0110513 Publication Model: Print-Electronic Cited Medium: Print ISSN: 0070-217X (Print) Linking ISSN: 0070217X NLM ISO Abbreviation: Curr Top Microbiol Immunol Subsets: MEDLINE

Distance-AF improves predicted protein structure models by AlphaFold2 with user-specified distance constraints.

Authors: Zhang, Yuanyuan Zhang, Zicong Kagaya, Yuki et al.

Source: Communications Biology. 9/30/2025, Vol. 8 Issue 1, p1-14. 14p.

The Role of Short-Chain Fatty Acids and Derived Metabolites in Osteoporosis.

Authors: Qiu G Xie S Luo W et al.

Source: Current osteoporosis reports [Curr Osteoporos Rep] 2026 Jul 24; Vol. 24 (1). Date of Electronic Publication: 2026 Jul 24.

Publication Type: Journal Article; Review

Journal Info: Publisher: Current Science Country of Publication: United States NLM ID: 101176492 Publication Model: Electronic Cited Medium: Internet ISSN: 1544-2241 (Electronic) Linking ISSN: 15441873 NLM ISO Abbreviation: Curr Osteoporos Rep Subsets: MEDLINE

Molecular basis for cross-activation of NPFF2R by a short PrRP-related peptide.

Authors: Li X Li S Shan H et al.

Source: Acta pharmacologica Sinica [Acta Pharmacol Sin] 2026 Jun; Vol. 47 (6), pp. 1671-1681. Date of Electronic Publication: 2026 Feb 04.

Publication Type: Journal Article

Journal Info: Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 100956087 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1745-7254 (Electronic) Linking ISSN: 16714083 NLM ISO Abbreviation: Acta Pharmacol Sin Subsets: MEDLINE

G protein-coupled receptors: pivotal hubs in gastric cancer malignancy—from multidimensional crosstalk to precision therapeutics.

Authors: Qin, Rong Fan, Xirui Huang, Yun et al.

Source: Journal of Translational Medicine. 8/7/2025, Vol. 23 Issue 1, p1-16. 16p.

ADGRF4 and ADGRL4 as novel prognostic biomarkers and potential therapeutic implications in stomach adenocarcinoma.

Authors: Wang JH Li MJ Zang DD et al.

Source: BMC gastroenterology [BMC Gastroenterol] 2026 May 13; Vol. 26 (1). Date of Electronic Publication: 2026 May 13.

Publication Type: Journal Article

Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 100968547 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-230X (Electronic) Linking ISSN: 1471230X NLM ISO Abbreviation: BMC Gastroenterol Subsets: MEDLINE

Decoding GPCR signaling reprogramming in cancer: molecular mechanisms and therapeutic implications.

Authors: Aldeyarbi S El-Deyarbi M Hussein AA et al.

Source: Molecular medicine (Cambridge, Mass.) [Mol Med] 2026 May 06; Vol. 32 (1). Date of Electronic Publication: 2026 May 06.

Publication Type: Journal Article; Review

Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 9501023 Publication Model: Electronic Cited Medium: Internet ISSN: 1528-3658 (Electronic) Linking ISSN: 10761551 NLM ISO Abbreviation: Mol Med Subsets: MEDLINE

Intracellular and dual-site inhibition of a bitter taste GPCR.

Authors: Dallal N Daniel Paz G Nir-Marom N et al.

Source: Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2026 Mar 30; Vol. 83 (1). Date of Electronic Publication: 2026 Mar 30.

Publication Type: Journal Article

Journal Info: Publisher: Springer Country of Publication: Switzerland NLM ID: 9705402 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-9071 (Electronic) Linking ISSN: 1420682X NLM ISO Abbreviation: Cell Mol Life Sci Subsets: MEDLINE

Targeting oncogenic NTSR1 with liensinine reprograms Gq-mediated signaling to suppress lung adenocarcinoma.

Authors: Wang Y Liu W Tao P et al.

Source: Chinese medicine [Chin Med] 2026 Mar 25; Vol. 21 (1). Date of Electronic Publication: 2026 Mar 25.

Publication Type: Journal Article

Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101265109 Publication Model: Electronic Cited Medium: Print ISSN: 1749-8546 (Print) Linking ISSN: 17498546 NLM ISO Abbreviation: Chin Med Subsets: PubMed not MEDLINE

Do GPCRs constitute the target of 30% of newly approved drugs in Germany?

Authors: Schröer S Seifert R

Source: Naunyn-Schmiedeberg's archives of pharmacology [Naunyn Schmiedebergs Arch Pharmacol] 2026 Feb; Vol. 399 (4), pp. 5575-5604. Date of Electronic Publication: 2025 Nov 06.

Publication Type: Journal Article

Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0326264 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1912 (Electronic) Linking ISSN: 00281298 NLM ISO Abbreviation: Naunyn Schmiedebergs Arch Pharmacol Subsets: MEDLINE

TRV130 inhibits colon cancer progression via suppressing the Hedgehog signaling pathway: in vitro and in vivo evidence.

Authors: Zhuang Y Jiang C Guo Y et al.

Source: Hereditas [Hereditas] 2026 Jan 19; Vol. 163 (1), pp. 26. Date of Electronic Publication: 2026 Jan 19.

Publication Type: Journal Article

Journal Info: Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 0374654 Publication Model: Electronic Cited Medium: Internet ISSN: 1601-5223 (Electronic) Linking ISSN: 00180661 NLM ISO Abbreviation: Hereditas Subsets: MEDLINE

The potential of MMP14 as a prognostic and immune biomarker in lung cancer.

Authors: Xiao J Zhu Z Zhang F et al.

Source: BMC cancer [BMC Cancer] 2026 Jan 17; Vol. 26 (1), pp. 256. Date of Electronic Publication: 2026 Jan 17.

Publication Type: Journal Article

Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 100967800 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2407 (Electronic) Linking ISSN: 14712407 NLM ISO Abbreviation: BMC Cancer Subsets: MEDLINE

Docking of virtual libraries identifies small-molecule agonists of neurotensin receptors with analgesic activity.

Authors: Panel N Vo DD Hübner H et al.

Source: Nature communications [Nat Commun] 2026 Jul 22; Vol. 17 (1). Date of Electronic Publication: 2026 Jul 22.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

Immune remodeling and metabolic reprogramming in chronic fatigue: insights into GPCR signaling and epigenetic regulation.

Authors: Hu Z Wang J Ma S et al.

Source: Frontiers in immunology [Front Immunol] 2026 May 15; Vol. 17, pp. 1806420. Date of Electronic Publication: 2026 May 15 (Print Publication: 2026).

Publication Type: Journal Article; Review

Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE

In silico docking yields small molecule negative allosteric modulators targeting the core of Frizzled 7.

Authors: Scharf MM Kinsolving J Grätz L et al.

Source: Nature communications [Nat Commun] 2025 Dec 14; Vol. 16 (1), pp. 11138. Date of Electronic Publication: 2025 Dec 14.

Publication Type: Journal Article

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE