Search Results - "Marchant JS"

TRPM8 is a non-canonical target of 7-nitrobenzodiazepines.

Authors: Elkin L Chulkov EG Enders JD et al.

Source: Cell chemical biology [Cell Chem Biol] 2026 Jul 29. Date of Electronic Publication: 2026 Jul 29.

Publication Type: Journal Article

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101676030 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2451-9448 (Electronic) Linking ISSN: 24519448 NLM ISO Abbreviation: Cell Chem Biol Subsets: MEDLINE

Extensive parasite transmission and variation in a functional receptor associated with drug resistance in endemic Schistosoma mansoni.

Authors: Berger DJ Park SK Crellen T et al.

Source: Science advances [Sci Adv] 2026 Jul 17; Vol. 12 (29), pp. eadt3721. Date of Electronic Publication: 2026 Jul 17.

Publication Type: Journal Article

Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101653440 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2375-2548 (Electronic) Linking ISSN: 23752548 NLM ISO Abbreviation: Sci Adv Subsets: MEDLINE

Novel 1H-1,2,3-Triazole Derivatives of Praziquantel with TRPMPZQ Modulatory Activity and Antiparasitic Effects on Larvae, Juvenile, and Adult Worms of Schistosoma mansoni.

Authors: Junior FPS Dantas RF Park SK et al.

Source: ACS infectious diseases [ACS Infect Dis] 2026 Apr 10; Vol. 12 (4), pp. 1301-1312. Date of Electronic Publication: 2025 Dec 10.

Publication Type: Journal Article

Journal Info: Publisher: ACS Publications Country of Publication: United States NLM ID: 101654580 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2373-8227 (Electronic) Linking ISSN: 23738227 NLM ISO Abbreviation: ACS Infect Dis Subsets: MEDLINE

Meclonazepam sensitivity of parasitic flatworms correlates with TRPMMCLZ sensitivity to meclonazepam.

Authors: Rohr CM McCusker P Kaethner M et al.

Source: International journal for parasitology. Drugs and drug resistance [Int J Parasitol Drugs Drug Resist] 2026 Apr; Vol. 30, pp. 100634. Date of Electronic Publication: 2026 Jan 20.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101576715 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2211-3207 (Electronic) Linking ISSN: 22113207 NLM ISO Abbreviation: Int J Parasitol Drugs Drug Resist Subsets: MEDLINE

TRPtracker: a community database for monitoring praziquantel sensitivity at TRPMPZQ variants.

Authors: Rohr CM Park SK Aguiar-Martins K et al.

Source: International journal for parasitology. Drugs and drug resistance [Int J Parasitol Drugs Drug Resist] 2026 Apr; Vol. 30, pp. 100639. Date of Electronic Publication: 2026 Mar 18.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101576715 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2211-3207 (Electronic) Linking ISSN: 22113207 NLM ISO Abbreviation: Int J Parasitol Drugs Drug Resist Subsets: MEDLINE

Clonazepam activates the transient receptor potential melastatin 8 (TRPM8) ion channel.

Authors: Elkin L Chulkov EG Enders J et al.

Source: BioRxiv : the preprint server for biology [bioRxiv] 2026 Jan 22. Date of Electronic Publication: 2026 Jan 22.

Publication Type: Journal Article; Preprint

Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

Liquid liquid phase separation of the intrinsically disordered protein JPT2 compartmentalizes components of NAADP-evoked Ca²⁺ signaling.

Authors: Kumar S Gunaratne GS Cornish J et al.

Source: BioRxiv : the preprint server for biology [bioRxiv] 2026 Jan 11. Date of Electronic Publication: 2026 Jan 11.

Publication Type: Journal Article; Preprint

Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

Target-Based Design of Praziquantel Analogs at Cestode TRPMPZQ.

Authors: Sprague DJ Park SK Kaethner M et al.

Source: ACS infectious diseases [ACS Infect Dis] 2025 Sep 12; Vol. 11 (9), pp. 2383-2390. Date of Electronic Publication: 2025 Aug 03.

Publication Type: Journal Article

Journal Info: Publisher: ACS Publications Country of Publication: United States NLM ID: 101654580 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2373-8227 (Electronic) Linking ISSN: 23738227 NLM ISO Abbreviation: ACS Infect Dis Subsets: MEDLINE

Progress interrogating TRPMPZQ as the target of praziquantel.

Authors: Marchant JS; Department of Cell Biology, Neurobiology & Anatomy, Medical College of Wisconsin, Milwaukee, Wisconsin, United States of America.

Source: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2024 Feb 15; Vol. 18 (2), pp. e0011929. Date of Electronic Publication: 2024 Feb 15 (Print Publication: 2024).

Publication Type: Journal Article; Review

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101291488 Publication Model: eCollection Cited Medium: Internet ISSN: 1935-2735 (Electronic) Linking ISSN: 19352727 NLM ISO Abbreviation: PLoS Negl Trop Dis Subsets: MEDLINE

TRPtracker: a community database for monitoring praziquantel sensitivity at TRPMPZQ variants.

Authors: Rohr CM Park SK Aguiar-Martins K et al.

Source: BioRxiv : the preprint server for biology [bioRxiv] 2025 Aug 27. Date of Electronic Publication: 2025 Aug 27.

Publication Type: Journal Article; Preprint

Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

Metabolism of (R)-Praziquantel versus the Activation of a Parasite Transient Receptor Potential Melastatin Ion Channel.

Authors: Friedrich L Park SK Ballard P et al.

Source: ChemMedChem [ChemMedChem] 2023 Sep 15; Vol. 18 (18), pp. e202300140. Date of Electronic Publication: 2023 Jun 15.

Publication Type: Journal Article; Research Support, N.I.H., Extramural

Journal Info: Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 101259013 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1860-7187 (Electronic) Linking ISSN: 18607179 NLM ISO Abbreviation: ChemMedChem Subsets: MEDLINE

Convergent activation of two-pore channels mediated by the NAADP-binding proteins JPT2 and LSM12.

Authors: Gunaratne GS Brailoiu E Kumar S et al.

Source: Science signaling [Sci Signal] 2023 Aug 22; Vol. 16 (799), pp. eadg0485. Date of Electronic Publication: 2023 Aug 22.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101465400 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1937-9145 (Electronic) Linking ISSN: 19450877 NLM ISO Abbreviation: Sci Signal Subsets: MEDLINE

Convergent activation of Ca²⁺ permeability in two-pore channel 2 through distinct molecular routes.

Authors: Saito R Mu Q Yuan Y et al.

Source: Science signaling [Sci Signal] 2023 Aug 22; Vol. 16 (799), pp. eadg0661. Date of Electronic Publication: 2023 Aug 22.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101465400 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1937-9145 (Electronic) Linking ISSN: 19450877 NLM ISO Abbreviation: Sci Signal Subsets: MEDLINE

Molecular and cellular basis of praziquantel action in the cardiovascular system.

Authors: Yahya NA Lanham JK Sprague DJ et al.

Source: American journal of physiology. Cell physiology [Am J Physiol Cell Physiol] 2023 Feb 01; Vol. 324 (2), pp. C573-C587. Date of Electronic Publication: 2023 Jan 09.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901225 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-1563 (Electronic) Linking ISSN: 03636143 NLM ISO Abbreviation: Am J Physiol Cell Physiol Subsets: MEDLINE

NAADP signaling: Master manipulation.

Authors: Mu Q Harris JL Yule DI et al.

Source: Cell calcium [Cell Calcium] 2024 Dec; Vol. 124, pp. 102969. Date of Electronic Publication: 2024 Nov 17.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8006226 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-1991 (Electronic) Linking ISSN: 01434160 NLM ISO Abbreviation: Cell Calcium Subsets: MEDLINE; In Process

Quantal leaps in understanding Ca²⁺ signaling: A "Taylored" approach.

Authors: Patel S Bootman MD Rossi A et al.

Source: Science signaling [Sci Signal] 2022 Nov 29; Vol. 15 (762), pp. eadf0308. Date of Electronic Publication: 2022 Nov 29.

Publication Type: Journal Article; Review

Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101465400 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1937-9145 (Electronic) Linking ISSN: 19450877 NLM ISO Abbreviation: Sci Signal Subsets: MEDLINE

Implementation of an Active Screening Program for SARS-CoV2 - Experience at an Academic Medical Center.

Authors: Udani R Schilter KF Hillmer RE et al.

Source: WMJ : official publication of the State Medical Society of Wisconsin [WMJ] 2022 Oct; Vol. 121 (3), pp. 235-238.

Publication Type: Journal Article

Journal Info: Publisher: University of Wisconsin School of Medicine and Public Health Country of Publication: United States NLM ID: 9716054 Publication Model: Print Cited Medium: Internet ISSN: 2379-3961 (Electronic) Linking ISSN: 10981861 NLM ISO Abbreviation: WMJ Subsets: MEDLINE

Extensive transmission and variation in a functional receptor for praziquantel resistance in endemic Schistosoma mansoni.

Authors: Berger DJ Park SK Crellen T et al.

Source: BioRxiv : the preprint server for biology [bioRxiv] 2024 Sep 03. Date of Electronic Publication: 2024 Sep 03.

Publication Type: Journal Article; Preprint

Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

Target-based discovery of a broad-spectrum flukicide.

Authors: Sprague DJ Park SK Gramberg S et al.

Source: Nature structural & molecular biology [Nat Struct Mol Biol] 2024 Sep; Vol. 31 (9), pp. 1386-1393. Date of Electronic Publication: 2024 May 07.

Publication Type: Journal Article

Journal Info: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101186374 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1545-9985 (Electronic) Linking ISSN: 15459985 NLM ISO Abbreviation: Nat Struct Mol Biol Subsets: MEDLINE

Genetic analysis of praziquantel response in schistosome parasites implicates a transient receptor potential channel.

Authors: Le Clec'h W Chevalier FD Mattos ACA et al.

Source: Science translational medicine [Sci Transl Med] 2021 Dec 22; Vol. 13 (625), pp. eabj9114. Date of Electronic Publication: 2021 Dec 22.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE