Search Results - "Mathis, Nicolas"

Programmable genome editing in human cells using RNA-guided bridge recombinases.

Authors: Pelea, Oana Tálas, András Carrera, Javier Fernández et al.

Source: Science. 3/12/2026, Vol. 391 Issue 6790, p1-17. 17p.

Subjects: Recombinases, RNA, Genome editing, Chromosome inversions, Human cell culture

Machine learning prediction of prime editing efficiency across diverse chromatin contexts.

Authors: Mathis, Nicolas Allam, Ahmed Tálas, András et al.

Source: Nature Biotechnology. May2025, Vol. 43 Issue 5, p712-719. 8p.

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Predicting prime editing efficiency and product purity by deep learning.

Authors: Mathis, Nicolas Allam, Ahmed Kissling, Lucas et al.

Source: Nature Biotechnology. Aug2023, Vol. 41 Issue 8, p1151-1159. 9p.

Publisher Correction: Machine learning prediction of prime editing efficiency across diverse chromatin contexts.

Authors: Mathis, Nicolas Allam, Ahmed Tálas, András et al.

Source: Nature Biotechnology. May2025, Vol. 43 Issue 5, p822-822. 1p.

Characterization of two novel intronic OPA1 mutations resulting in aberrant pre-mRNA splicing.

Authors: Bolognini, Ramona Gerth-Kahlert, Christina Abegg, Mathias et al.

Source: BMC Medical Genetics. 2/28/2017, Vol. 18, p1-9. 9p.

Stress-triggered hematopoietic stem cell proliferation relies on PrimPol-mediated repriming.

Authors: Jacobs, Kurt Doerdelmann, Cyril Krietsch, Jana et al.

Source: Molecular Cell. Nov2022, Vol. 82 Issue 21, p4176-4176. 1p.

Prime editing of a pathogenic Scn1a allele ameliorates seizure phenotypes in a GEFS⁺ mouse model.

Authors: Kissling L Pietrafesa F Ranucci M et al.

Source: Science translational medicine [Sci Transl Med] 2026 May 13; Vol. 18 (849), pp. eadz2557. Date of Electronic Publication: 2026 May 13.

Publication Type: Journal Article

Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE

Spatial profiling of gene editing by in situ sequencing in mice and macaques.

Authors: Janjuha S Haenggi T Chamberlain TC et al.

Source: Nature biomedical engineering [Nat Biomed Eng] 2026 May; Vol. 10 (5), pp. 968-979. Date of Electronic Publication: 2025 Sep 19.

Publication Type: Journal Article

Journal Info: Publisher: Springer Nature Country of Publication: England NLM ID: 101696896 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2157-846X (Electronic) Linking ISSN: 2157846X NLM ISO Abbreviation: Nat Biomed Eng Subsets: MEDLINE

Predicting adenine base editing efficiencies in different cellular contexts by deep learning.

Authors: Kissling, Lucas Mollaysa, Amina Janjuha, Sharan et al.

Source: Genome biology 5/8/2025; Vol. 26 (1).

Journal Info: Publisher: BioMed Central ISSN: 1474-7596

Systematic pegRNA design with PRIDICT2.0 and ePRIDICT for efficient prime editing.

Authors: Mathis N Marquart KF Allam A et al.

Source: Nature protocols [Nat Protoc] 2026 Apr; Vol. 21 (4), pp. 1523-1543. Date of Electronic Publication: 2025 Aug 14.

Publication Type: Journal Article; Review; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101284307 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1750-2799 (Electronic) Linking ISSN: 17502799 NLM ISO Abbreviation: Nat Protoc Subsets: MEDLINE

LDLR variant classification through activity-normalized prime editing screening.

Authors: Zhou PJ Velimirovic M Yu T et al.

Source: BioRxiv : the preprint server for biology [bioRxiv] 2025 Dec 18. Date of Electronic Publication: 2025 Dec 18.

Publication Type: Journal Article; Preprint

Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

Enhancing prime editor activity by directed protein evolution in yeast.

Authors: Weber Y Böck D Ivașcu A et al.

Source: Nature communications [Nat Commun] 2024 Mar 07; Vol. 15 (1), pp. 2092. Date of Electronic Publication: 2024 Mar 07.

Publication Type: Journal Article

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

Effective genome editing with an enhanced ISDra2 TnpB system and deep learning-predicted ωRNAs.

Authors: Marquart KF Mathis N Mollaysa A et al.

Source: Nature methods [Nat Methods] 2024 Nov; Vol. 21 (11), pp. 2084-2093. Date of Electronic Publication: 2024 Sep 23.

Publication Type: Journal Article

Journal Info: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101215604 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1548-7105 (Electronic) Linking ISSN: 15487091 NLM ISO Abbreviation: Nat Methods Subsets: MEDLINE

In vivo prime editing of a metabolic liver disease in mice.

Authors: Böck D Rothgangl T Villiger L et al.

Source: Science translational medicine [Sci Transl Med] 2022 Mar 16; Vol. 14 (636), pp. eabl9238. Date of Electronic Publication: 2022 Mar 16.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE

Continuous directed evolution of a compact CjCas9 variant with broad PAM compatibility.

Authors: Schmidheini L Mathis N Marquart KF et al.

Source: Nature chemical biology [Nat Chem Biol] 2024 Mar; Vol. 20 (3), pp. 333-343. Date of Electronic Publication: 2023 Sep 21.

Publication Type: Journal Article

Journal Info: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101231976 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1552-4469 (Electronic) Linking ISSN: 15524450 NLM ISO Abbreviation: Nat Chem Biol Subsets: MEDLINE

A paracrine activin A-mDia2 axis promotes squamous carcinogenesis via fibroblast reprogramming.

Authors: Cangkrama M Wietecha M Mathis N et al.

Source: EMBO molecular medicine [EMBO Mol Med] 2020 Apr 07; Vol. 12 (4), pp. e11466. Date of Electronic Publication: 2020 Mar 09.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: EMBO Press Country of Publication: Germany NLM ID: 101487380 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1757-4684 (Electronic) Linking ISSN: 17574676 NLM ISO Abbreviation: EMBO Mol Med Subsets: MEDLINE

Replacing the SpCas9 HNH domain by deaminases generates compact base editors with an alternative targeting scope.

Authors: Villiger L Schmidheini L Mathis N et al.

Source: Molecular therapy. Nucleic acids [Mol Ther Nucleic Acids] 2021 Aug 26; Vol. 26, pp. 502-510. Date of Electronic Publication: 2021 Aug 26 (Print Publication: 2021).

Publication Type: Journal Article

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101581621 Publication Model: eCollection Cited Medium: Print ISSN: 2162-2531 (Print) Linking ISSN: 21622531 NLM ISO Abbreviation: Mol Ther Nucleic Acids Subsets: PubMed not MEDLINE

Osteoblast interaction with DLC-coated Si substrates.

Authors: Chai F Mathis N Blanchemain N et al.

Source: Acta biomaterialia [Acta Biomater] 2008 Sep; Vol. 4 (5), pp. 1369-81. Date of Electronic Publication: 2008 Apr 29.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Elsevier Country of Publication: England NLM ID: 101233144 Publication Model: Print-Electronic Cited Medium: Print ISSN: 1742-7061 (Print) Linking ISSN: 17427061 NLM ISO Abbreviation: Acta Biomater Subsets: MEDLINE