Search Results - "Mathison CJN"

Targeting Multiple KRAS Mutations with High-Affinity Macrocyclic Inhibitors: From Discovery to Preclinical Validation.

Authors: Phillips DP Alper PB Cho CY et al.

Source: Journal of medicinal chemistry [J Med Chem] 2026 Jun 11; Vol. 69 (11), pp. 13165-13187. Date of Electronic Publication: 2026 May 19.

Publication Type: Journal Article

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

Triggering AHR resolves TGF-β1 induced fibroblast activation and promotes AT1 cell regeneration in alveolar organoids.

Authors: Hagan AS Williams S Mathison CJN et al.

Source: Communications biology [Commun Biol] 2025 Jul 09; Vol. 8 (1), pp. 1025. Date of Electronic Publication: 2025 Jul 09.

Publication Type: Journal Article

Journal Info: Publisher: Nature Publishing Group UK Country of Publication: England NLM ID: 101719179 Publication Model: Electronic Cited Medium: Internet ISSN: 2399-3642 (Electronic) Linking ISSN: 23993642 NLM ISO Abbreviation: Commun Biol Subsets: MEDLINE

Antitarget Selectivity and Tolerability of Novel Pyrrolo[2,3-d]pyrimidine RET Inhibitors.

Authors: Mathison CJN Yang Y Nelson J et al.

Source: ACS medicinal chemistry letters [ACS Med Chem Lett] 2021 Nov 06; Vol. 12 (12), pp. 1912-1919. Date of Electronic Publication: 2021 Nov 06 (Print Publication: 2021).

Publication Type: Journal Article

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101521073 Publication Model: eCollection Cited Medium: Print ISSN: 1948-5875 (Print) Linking ISSN: 19485875 NLM ISO Abbreviation: ACS Med Chem Lett Subsets: PubMed not MEDLINE

Discovery and Characterization of Clinical Candidate LXE408 as a Kinetoplastid-Selective Proteasome Inhibitor for the Treatment of Leishmaniases.

Authors: Nagle A Biggart A Be C et al.

Source: Journal of medicinal chemistry [J Med Chem] 2020 Oct 08; Vol. 63 (19), pp. 10773-10781. Date of Electronic Publication: 2020 Jul 29.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

Efficacy and Tolerability of Pyrazolo[1,5-a]pyrimidine RET Kinase Inhibitors for the Treatment of Lung Adenocarcinoma.

Authors: Mathison CJN Chianelli D Rucker PV et al.

Source: ACS medicinal chemistry letters [ACS Med Chem Lett] 2020 Feb 12; Vol. 11 (4), pp. 558-565. Date of Electronic Publication: 2020 Feb 12 (Print Publication: 2020).

Publication Type: Journal Article

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101521073 Publication Model: eCollection Cited Medium: Print ISSN: 1948-5875 (Print) Linking ISSN: 19485875 NLM ISO Abbreviation: ACS Med Chem Lett Subsets: PubMed not MEDLINE

Discovery of Orally Active Hydroxyethylamine Based SPPL2a Inhibitors.

Authors: Velcicky J Mathison CJN Nikulin V et al.

Source: ACS medicinal chemistry letters [ACS Med Chem Lett] 2019 May 23; Vol. 10 (6), pp. 887-892. Date of Electronic Publication: 2019 May 23 (Print Publication: 2019).

Publication Type: Journal Article

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101521073 Publication Model: eCollection Cited Medium: Print ISSN: 1948-5875 (Print) Linking ISSN: 19485875 NLM ISO Abbreviation: ACS Med Chem Lett Subsets: PubMed not MEDLINE