Search Results - "McClements ME"

Investigating ethnicity-related variability in the human L-cone spectral sensitivity function.

Authors: Schneider AC Morimoto T McClements ME et al.

Source: Vision research [Vision Res] 2026 Jun; Vol. 243, pp. 108769. Date of Electronic Publication: 2026 Feb 19.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 0417402 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-5646 (Electronic) Linking ISSN: 00426989 NLM ISO Abbreviation: Vision Res Subsets: MEDLINE

Design and Validation of Mirtron-Mediated RNA Interference for Gene Therapy.

Authors: Zheng Q Orlans HO Staurenghi F et al.

Source: Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2026; Vol. 3023, pp. 195-206.

Publication Type: Journal Article

Journal Info: Publisher: Humana Press Country of Publication: United States NLM ID: 9214969 Publication Model: Print Cited Medium: Internet ISSN: 1940-6029 (Electronic) Linking ISSN: 10643745 NLM ISO Abbreviation: Methods Mol Biol Subsets: MEDLINE

Pre-existing retinal inflammation exacerbates gene therapy-associated uveitis in more rapidly progressive retinal degeneration.

Authors: John MC Martinez-Fernandez de la Camara C Salman A et al.

Source: Molecular therapy. Advances [Mol Ther Adv] 2025 Dec 26; Vol. 34 (1), pp. 201652. Date of Electronic Publication: 2025 Dec 26 (Print Publication: 2026).

Publication Type: Journal Article

Journal Info: Country of Publication: United States NLM ID: 9919257804006676 Publication Model: eCollection Cited Medium: Internet ISSN: 3117-387X (Electronic) Linking ISSN: 3117387X NLM ISO Abbreviation: Mol Ther Adv Subsets: PubMed not MEDLINE

Gene Therapy Strategies for the Treatment of Bestrophinopathies.

Authors: Haldrup SB McClements ME Cehajic-Kapetanovic J et al.

Source: International journal of molecular sciences [Int J Mol Sci] 2025 Sep 26; Vol. 26 (19). Date of Electronic Publication: 2025 Sep 26.

Publication Type: Journal Article; Review

Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

CRISPR targeting of SNPs associated with age-related macular degeneration in ARPE-19 cells: a potential model for manipulating the complement system.

Authors: Salman A Song WK Storm T et al.

Source: Gene therapy [Gene Ther] 2025 Mar; Vol. 32 (2), pp. 132-141. Date of Electronic Publication: 2025 Mar 18.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 9421525 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5462 (Electronic) Linking ISSN: 09697128 NLM ISO Abbreviation: Gene Ther Subsets: MEDLINE

Programmable RNA editing with endogenous ADAR enzymes - a feasible option for the treatment of inherited retinal disease?

Authors: Bellingrath JS McClements ME Fischer MD et al.

Source: Frontiers in molecular neuroscience [Front Mol Neurosci] 2023 May 24; Vol. 16, pp. 1092913. Date of Electronic Publication: 2023 May 24 (Print Publication: 2023).

Publication Type: Journal Article; Review

Journal Info: Publisher: Frontiers Research Foundation Country of Publication: Switzerland NLM ID: 101477914 Publication Model: eCollection Cited Medium: Print ISSN: 1662-5099 (Print) Linking ISSN: 16625099 NLM ISO Abbreviation: Front Mol Neurosci Subsets: PubMed not MEDLINE

Comparison of CRISPR-Cas13b RNA base editing approaches for USH2A-associated inherited retinal degeneration.

Authors: Fry LE Major L Salman A et al.

Source: Communications biology [Commun Biol] 2025 Feb 08; Vol. 8 (1), pp. 200. Date of Electronic Publication: 2025 Feb 08.

Publication Type: Journal Article; Comparative Study

Journal Info: Publisher: Nature Publishing Group UK Country of Publication: England NLM ID: 101719179 Publication Model: Electronic Cited Medium: Internet ISSN: 2399-3642 (Electronic) Linking ISSN: 23993642 NLM ISO Abbreviation: Commun Biol Subsets: MEDLINE

Envisioning the development of a CRISPR-Cas mediated base editing strategy for a patient with a novel pathogenic CRB1 single nucleotide variant.

Authors: Bellingrath JS McClements ME Shanks M et al.

Source: Ophthalmic genetics [Ophthalmic Genet] 2022 Oct; Vol. 43 (5), pp. 661-670. Date of Electronic Publication: 2022 May 10.

Publication Type: Case Reports; Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Informa Healthcare Country of Publication: England NLM ID: 9436057 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1744-5094 (Electronic) Linking ISSN: 13816810 NLM ISO Abbreviation: Ophthalmic Genet Subsets: MEDLINE

CRISPR DNA Base Editing Strategies for Treating Retinitis Pigmentosa Caused by Mutations in Rhodopsin.

Authors: Kaukonen M McClements ME MacLaren RE

Source: Genes [Genes (Basel)] 2022 Jul 26; Vol. 13 (8). Date of Electronic Publication: 2022 Jul 26.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101551097 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4425 (Electronic) Linking ISSN: 20734425 NLM ISO Abbreviation: Genes (Basel) Subsets: MEDLINE

The Scope of Pathogenic ABCA4 Mutations Targetable by CRISPR DNA Base Editing Systems-A Systematic Review.

Authors: Piotter E McClements ME MacLaren RE

Source: Frontiers in genetics [Front Genet] 2022 Jan 27; Vol. 12, pp. 814131. Date of Electronic Publication: 2022 Jan 27 (Print Publication: 2021).

Publication Type: Journal Article; Review

Journal Info: Publisher: Frontiers Research Foundation Country of Publication: Switzerland NLM ID: 101560621 Publication Model: eCollection Cited Medium: Print ISSN: 1664-8021 (Print) Linking ISSN: 16648021 NLM ISO Abbreviation: Front Genet Subsets: PubMed not MEDLINE

Gene Therapies in Clinical Development to Treat Retinal Disorders.

Authors: McClements ME Elsayed MEAA Major L et al.

Source: Molecular diagnosis & therapy [Mol Diagn Ther] 2024 Sep; Vol. 28 (5), pp. 575-591. Date of Electronic Publication: 2024 Jul 02.

Publication Type: Journal Article; Review; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Adis, Springer International Country of Publication: New Zealand NLM ID: 101264260 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1179-2000 (Electronic) Linking ISSN: 11771062 NLM ISO Abbreviation: Mol Diagn Ther Subsets: MEDLINE

Genetic therapies and potential therapeutic applications of CRISPR activators in the eye.

Authors: Ng BW Kaukonen MK McClements ME et al.

Source: Progress in retinal and eye research [Prog Retin Eye Res] 2024 Sep; Vol. 102, pp. 101289. Date of Electronic Publication: 2024 Aug 08.

Publication Type: Journal Article; Review

Journal Info: Publisher: Pergamon Country of Publication: England NLM ID: 9431859 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-1635 (Electronic) Linking ISSN: 13509462 NLM ISO Abbreviation: Prog Retin Eye Res Subsets: MEDLINE

In Silico Analysis of Pathogenic CRB1 Single Nucleotide Variants and Their Amenability to Base Editing as a Potential Lead for Therapeutic Intervention.

Authors: Bellingrath JS McClements ME Kaukonen M et al.

Source: Genes [Genes (Basel)] 2021 Nov 27; Vol. 12 (12). Date of Electronic Publication: 2021 Nov 27.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101551097 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4425 (Electronic) Linking ISSN: 20734425 NLM ISO Abbreviation: Genes (Basel) Subsets: MEDLINE

Single-cell transcriptomic analysis of retinal immune regulation and blood-retinal barrier function during experimental autoimmune uveitis.

Authors: Quinn J Salman A Paluch C et al.

Source: Scientific reports [Sci Rep] 2024 Aug 28; Vol. 14 (1), pp. 20033. Date of Electronic Publication: 2024 Aug 28.

Publication Type: Journal Article

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

Rescue of cone and rod photoreceptor function in a CDHR1-model of age-related retinal degeneration.

Authors: Yusuf IH Burgoyne T Salman A et al.

Source: Molecular therapy : the journal of the American Society of Gene Therapy [Mol Ther] 2024 May 01; Vol. 32 (5), pp. 1445-1460. Date of Electronic Publication: 2024 Mar 19.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 100890581 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1525-0024 (Electronic) Linking ISSN: 15250016 NLM ISO Abbreviation: Mol Ther Subsets: MEDLINE

Mirtron-mediated RNA knockdown/replacement therapy for the treatment of dominant retinitis pigmentosa.

Authors: Orlans HO McClements ME Barnard AR et al.

Source: Nature communications [Nat Commun] 2021 Aug 16; Vol. 12 (1), pp. 4934. Date of Electronic Publication: 2021 Aug 16.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

An analysis of the Kozak consensus in retinal genes and its relevance to gene therapy.

Authors: McClements ME Butt A Piotter E et al.

Source: Molecular vision [Mol Vis] 2021 May 08; Vol. 27, pp. 233-242. Date of Electronic Publication: 2021 May 08 (Print Publication: 2021).

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Molecular Vision Country of Publication: United States NLM ID: 9605351 Publication Model: eCollection Cited Medium: Internet ISSN: 1090-0535 (Electronic) Linking ISSN: 10900535 NLM ISO Abbreviation: Mol Vis Subsets: MEDLINE

Accurate Quantification of AAV Vector Genomes by Quantitative PCR.

Authors: Martinez-Fernandez de la Camara C McClements ME MacLaren RE

Source: Genes [Genes (Basel)] 2021 Apr 19; Vol. 12 (4). Date of Electronic Publication: 2021 Apr 19.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101551097 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4425 (Electronic) Linking ISSN: 20734425 NLM ISO Abbreviation: Genes (Basel) Subsets: MEDLINE

Analysis of Pathogenic Variants Correctable With CRISPR Base Editing Among Patients With Recessive Inherited Retinal Degeneration.

Authors: Fry LE McClements ME MacLaren RE

Source: JAMA ophthalmology [JAMA Ophthalmol] 2021 Mar 01; Vol. 139 (3), pp. 319-328.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Medical Association Country of Publication: United States NLM ID: 101589539 Publication Model: Print Cited Medium: Internet ISSN: 2168-6173 (Electronic) Linking ISSN: 21686165 NLM ISO Abbreviation: JAMA Ophthalmol Subsets: MEDLINE

AAV Induced Expression of Human Rod and Cone Opsin in Bipolar Cells of a Mouse Model of Retinal Degeneration.

Authors: McClements ME Staurenghi F Visel M et al.

Source: BioMed research international [Biomed Res Int] 2021 Feb 09; Vol. 2021, pp. 1-8.

Publication Type: Journal Article

Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 101600173 Publication Model: Print Cited Medium: Internet ISSN: 2314-6141 (Electronic) NLM ISO Abbreviation: Biomed Res Int Subsets: MEDLINE