Search Results - "Modi NB"

Pharmacokinetics and Pharmacodynamics of Rusfertide, a Hepcidin Mimetic, Following Subcutaneous Administration of a Lyophilized Powder Formulation in Healthy Volunteers.

Authors: Modi NB Khanna S Rudraraju S et al.

Source: Drugs in R&D [Drugs R D] 2024 Dec; Vol. 24 (4), pp. 539-552. Date of Electronic Publication: 2024 Nov 15.

Publication Type: Journal Article; Randomized Controlled Trial

Journal Info: Publisher: Adis, Springer International Country of Publication: New Zealand NLM ID: 100883647 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1179-6901 (Electronic) Linking ISSN: 11745886 NLM ISO Abbreviation: Drugs R D Subsets: MEDLINE

Rusfertide rapidly decreases hematocrit in patients with suboptimally controlled polycythemia vera.

Authors: Chew LP Ginzburg YZ Kirubamoorthy K et al.

Source: Leukemia research [Leuk Res] 2025 Dec; Vol. 159, pp. 108132. Date of Electronic Publication: 2025 Oct 29.

Publication Type: Journal Article

Journal Info: Publisher: Pergamon Press Country of Publication: England NLM ID: 7706787 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-5835 (Electronic) Linking ISSN: 01452126 NLM ISO Abbreviation: Leuk Res Subsets: MEDLINE

Pharmacokinetics, pharmacodynamics, and tolerability of an aqueous formulation of rusfertide (PTG-300), a hepcidin mimetic, in healthy volunteers: A double-blind first-in-human study.

Authors: Modi NB Shames R Lickliter JD et al.

Source: European journal of haematology [Eur J Haematol] 2024 Sep; Vol. 113 (3), pp. 340-350. Date of Electronic Publication: 2024 May 24.

Publication Type: Journal Article; Randomized Controlled Trial; Clinical Trial, Phase I

Journal Info: Publisher: Blackwell Country of Publication: England NLM ID: 8703985 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1600-0609 (Electronic) Linking ISSN: 09024441 NLM ISO Abbreviation: Eur J Haematol Subsets: MEDLINE

Evaluation of Rusfertide, a Hepcidin Mimetic, on Cardiac Repolarization: A Randomized, Placebo- and Positive-Controlled Crossover Thorough QT Study in Healthy Participants.

Authors: Modi NB Dinh P Xue H et al.

Source: Clinical therapeutics [Clin Ther] 2025 Nov; Vol. 47 (11), pp. 1043-1052. Date of Electronic Publication: 2025 Sep 30.

Publication Type: Journal Article; Randomized Controlled Trial

Journal Info: Publisher: Excerpta Medica Country of Publication: United States NLM ID: 7706726 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-114X (Electronic) Linking ISSN: 01492918 NLM ISO Abbreviation: Clin Ther Subsets: MEDLINE

Translational Pharmacokinetics of Icotrokinra, a Targeted Oral Peptide that Selectively Blocks Interleukin-23 Receptor and Inhibits Signaling.

Authors: Knight B Tammara B Modi NB et al.

Source: Dermatology and therapy [Dermatol Ther (Heidelb)] 2025 Sep; Vol. 15 (9), pp. 2495-2520. Date of Electronic Publication: 2025 Jul 08.

Publication Type: Journal Article

Journal Info: Publisher: Springer Healthcare Communications Country of Publication: Switzerland NLM ID: 101590450 Publication Model: Print-Electronic Cited Medium: Print ISSN: 2193-8210 (Print) NLM ISO Abbreviation: Dermatol Ther (Heidelb) Subsets: PubMed not MEDLINE

Multiple-Dose Pharmacokinetics, Pharmacodynamics, Safety, and Tolerability of Subcutaneous Rusfertide, a Hepcidin Mimetic, in Healthy Subjects.

Authors: Modi NB Dinh P Ajari I

Source: Clinical pharmacology in drug development [Clin Pharmacol Drug Dev] 2025 Apr; Vol. 14 (4), pp. 311-323. Date of Electronic Publication: 2025 Jan 29.

Publication Type: Journal Article; Randomized Controlled Trial; Clinical Trial, Phase I; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 101572899 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2160-7648 (Electronic) Linking ISSN: 2160763X NLM ISO Abbreviation: Clin Pharmacol Drug Dev Subsets: MEDLINE

JNJ-77242113, a highly potent, selective peptide targeting the IL-23 receptor, provides robust IL-23 pathway inhibition upon oral dosing in rats and humans.

Authors: Fourie AM Cheng X Chang L et al.

Source: Scientific reports [Sci Rep] 2024 Jul 30; Vol. 14 (1), pp. 17515. Date of Electronic Publication: 2024 Jul 30.

Publication Type: Journal Article

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

Rusfertide for iron overload in haemochromatosis - Authors' reply.

Authors: Kowdley KV Modi NB Valone FH

Source: The lancet. Gastroenterology & hepatology [Lancet Gastroenterol Hepatol] 2024 Mar; Vol. 9 (3), pp. 200-201.

Publication Type: Letter; Comment

Journal Info: Publisher: Elsevier B.V Country of Publication: Netherlands NLM ID: 101690683 Publication Model: Print Cited Medium: Internet ISSN: 2468-1253 (Electronic) NLM ISO Abbreviation: Lancet Gastroenterol Hepatol Subsets: MEDLINE

Rusfertide, a Hepcidin Mimetic, for Control of Erythrocytosis in Polycythemia Vera.

Authors: Kremyanskaya M Kuykendall AT Pemmaraju N et al.

Corporate Authors: Kremyanskaya M Kuykendall AT Pemmaraju N et al.

Source: The New England journal of medicine [N Engl J Med] 2024 Feb 22; Vol. 390 (8), pp. 723-735.

Publication Type: Journal Article; Multicenter Study; Randomized Controlled Trial

Journal Info: Publisher: Massachusetts Medical Society Country of Publication: United States NLM ID: 0255562 Publication Model: Print Cited Medium: Internet ISSN: 1533-4406 (Electronic) Linking ISSN: 00284793 NLM ISO Abbreviation: N Engl J Med Subsets: MEDLINE

Rusfertide for the treatment of iron overload in HFE-related haemochromatosis: an open-label, multicentre, proof-of-concept phase 2 trial.

Authors: Kowdley KV Modi NB Peltekian K et al.

Source: The lancet. Gastroenterology & hepatology [Lancet Gastroenterol Hepatol] 2023 Dec; Vol. 8 (12), pp. 1118-1128. Date of Electronic Publication: 2023 Oct 17.

Publication Type: Clinical Trial, Phase II; Multicenter Study; Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Elsevier B.V Country of Publication: Netherlands NLM ID: 101690683 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2468-1253 (Electronic) NLM ISO Abbreviation: Lancet Gastroenterol Hepatol Subsets: MEDLINE

Pharmacokinetics of Rytary^®, An Extended-Release Capsule Formulation of Carbidopa-Levodopa.

Authors: Mittur A Gupta S Modi NB

Source: Clinical pharmacokinetics [Clin Pharmacokinet] 2017 Sep; Vol. 56 (9), pp. 999-1014.

Publication Type: Journal Article; Review; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Adis, part of Springer Science+Business Media Country of Publication: Switzerland NLM ID: 7606849 Publication Model: Print Cited Medium: Internet ISSN: 1179-1926 (Electronic) Linking ISSN: 03125963 NLM ISO Abbreviation: Clin Pharmacokinet Subsets: MEDLINE

PTG-100, an Oral α4β7 Antagonist Peptide: Preclinical Development and Phase 1 and 2a Studies in Ulcerative Colitis.

Authors: Sandborn WJ Mattheakis LC Modi NB et al.

Source: Gastroenterology [Gastroenterology] 2021 Dec; Vol. 161 (6), pp. 1853-1864.e10. Date of Electronic Publication: 2021 Aug 30.

Publication Type: Clinical Trial, Phase I; Clinical Trial, Phase II; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't

Journal Info: Publisher: W.B. Saunders Country of Publication: United States NLM ID: 0374630 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1528-0012 (Electronic) Linking ISSN: 00165085 NLM ISO Abbreviation: Gastroenterology Subsets: MEDLINE

Single- and Multiple-Dose Pharmacokinetics and Pharmacodynamics of PN-943, a Gastrointestinal-Restricted Oral Peptide Antagonist of α4β7, in Healthy Volunteers.

Authors: Modi NB Cheng X Mattheakis L et al.

Source: Clinical pharmacology in drug development [Clin Pharmacol Drug Dev] 2021 Nov; Vol. 10 (11), pp. 1263-1278. Date of Electronic Publication: 2021 May 04.

Publication Type: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 101572899 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2160-7648 (Electronic) Linking ISSN: 2160763X NLM ISO Abbreviation: Clin Pharmacol Drug Dev Subsets: MEDLINE

Application of Pharmacokinetics and Pharmacodynamics in Product Life Cycle Management. A Case Study with a Carbidopa-Levodopa Extended-Release Formulation.

Authors: Modi NB; Impax Specialty Pharma, a division of Impax Laboratories, Inc., 31047 Genstar Road, Hayward, California, 9454, USA. nmodi@impaxlabs.com.

Source: The AAPS journal [AAPS J] 2017 May; Vol. 19 (3), pp. 607-618. Date of Electronic Publication: 2017 Jan 24.

Publication Type: Journal Article; Review

Journal Info: Publisher: American Association of Pharmaceutical Scientists Country of Publication: United States NLM ID: 101223209 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1550-7416 (Electronic) Linking ISSN: 15507416 NLM ISO Abbreviation: AAPS J Subsets: MEDLINE

Pharmacokinetics, distribution, metabolism, and excretion of the dual reuptake inhibitor [(14)C]-nefopam in rats.

Authors: Yu J Solon E Shen H et al.

Source: Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 2016 Nov; Vol. 46 (11), pp. 1026-48. Date of Electronic Publication: 2016 Feb 29.

Publication Type: Journal Article

Journal Info: Publisher: Informa Healthcare Country of Publication: England NLM ID: 1306665 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1366-5928 (Electronic) Linking ISSN: 00498254 NLM ISO Abbreviation: Xenobiotica Subsets: MEDLINE

Pharmacokinetics, metabolism, and excretion of nefopam, a dual reuptake inhibitor in healthy male volunteers.

Authors: Sanga M Banach J Ledvina A et al.

Source: Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 2016 Nov; Vol. 46 (11), pp. 1001-16. Date of Electronic Publication: 2016 Jan 21.

Publication Type: Journal Article

Journal Info: Publisher: Informa Healthcare Country of Publication: England NLM ID: 1306665 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1366-5928 (Electronic) Linking ISSN: 00498254 NLM ISO Abbreviation: Xenobiotica Subsets: MEDLINE

Dose-Response Analysis of the Effect of Carbidopa-Levodopa Extended-Release Capsules (IPX066) in Levodopa-Naive Patients With Parkinson Disease.

Authors: Mao ZL Modi NB

Source: Journal of clinical pharmacology [J Clin Pharmacol] 2016 Aug; Vol. 56 (8), pp. 974-82. Date of Electronic Publication: 2016 Jan 18.

Publication Type: Clinical Trial, Phase III; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Wiley Country of Publication: England NLM ID: 0366372 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1552-4604 (Electronic) Linking ISSN: 00912700 NLM ISO Abbreviation: J Clin Pharmacol Subsets: MEDLINE

Comparison of the pharmacokinetics of an oral extended-release capsule formulation of carbidopa-levodopa (IPX066) with immediate-release carbidopa-levodopa (Sinemet(®)), sustained-release carbidopa-levodopa (Sinemet(®) CR), and carbidopa-levodopa-entacapone (Stalevo(®)).

Authors: Hsu A Yao HM Gupta S et al.

Source: Journal of clinical pharmacology [J Clin Pharmacol] 2015 Sep; Vol. 55 (9), pp. 995-1003. Date of Electronic Publication: 2015 May 20.

Publication Type: Journal Article; Randomized Controlled Trial

Journal Info: Publisher: Wiley Country of Publication: England NLM ID: 0366372 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1552-4604 (Electronic) Linking ISSN: 00912700 NLM ISO Abbreviation: J Clin Pharmacol Subsets: MEDLINE

Population pharmacodynamics of IPX066: an oral extended-release capsule formulation of carbidopa-levodopa, and immediate-release carbidopa-levodopa in patients with advanced Parkinson's disease.

Authors: Mao Z Hsu A Gupta S et al.

Source: Journal of clinical pharmacology [J Clin Pharmacol] 2013 May; Vol. 53 (5), pp. 523-31. Date of Electronic Publication: 2013 Feb 20.

Publication Type: Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Wiley Country of Publication: England NLM ID: 0366372 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1552-4604 (Electronic) Linking ISSN: 00912700 NLM ISO Abbreviation: J Clin Pharmacol Subsets: MEDLINE

Pharmacodynamics, Efficacy, and Safety of IPX203 in Parkinson Disease Patients With Motor Fluctuations.

Authors: Modi NB Mittur A Dinh P et al.

Source: Clinical neuropharmacology [Clin Neuropharmacol] 2019 Sep/Oct; Vol. 42 (5), pp. 149-156.

Publication Type: Clinical Trial; Journal Article; Multicenter Study

Journal Info: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 7607910 Publication Model: Print Cited Medium: Internet ISSN: 1537-162X (Electronic) Linking ISSN: 03625664 NLM ISO Abbreviation: Clin Neuropharmacol Subsets: MEDLINE