Search Results - "Musgaard M"

Ligand-induced conformational changes in the β1-adrenergic receptor revealed by hydrogen-deuterium exchange mass spectrometry.

Authors: Toporowska J Kapoor P Musgaard M et al.

Source: Nature communications [Nat Commun] 2024 Oct 18; Vol. 15 (1), pp. 8993. Date of Electronic Publication: 2024 Oct 18.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

Gain-of-function and loss-of-function variants in GRIA3 lead to distinct neurodevelopmental phenotypes.

Authors: Rinaldi B Bayat A Zachariassen LG et al.

Source: Brain : a journal of neurology [Brain] 2024 May 03; Vol. 147 (5), pp. 1837-1855.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 0372537 Publication Model: Print Cited Medium: Internet ISSN: 1460-2156 (Electronic) Linking ISSN: 00068950 NLM ISO Abbreviation: Brain Subsets: MEDLINE

Small-molecule positive allosteric modulation of homomeric kainate receptors GluK1-3: development of screening assays and insight into GluK3 structure.

Authors: Bay Y Venskutonytė R Frantsen SM et al.

Source: The FEBS journal [FEBS J] 2024 Apr; Vol. 291 (7), pp. 1506-1529. Date of Electronic Publication: 2024 Feb 23.

Publication Type: Journal Article

Journal Info: Publisher: Published by Blackwell Pub. on behalf of the Federation of European Biochemical Societies Country of Publication: England NLM ID: 101229646 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1742-4658 (Electronic) Linking ISSN: 1742464X NLM ISO Abbreviation: FEBS J Subsets: MEDLINE

Adiabatic-Bias Molecular Dynamics Simulations Reveal the Impact of Mutations on Muscarinic Antagonist Unbinding Kinetics.

Authors: Coricello A Chiaravalle AL Musgaard M et al.

Source: Journal of chemical information and modeling [J Chem Inf Model] 2025 Jul 14; Vol. 65 (13), pp. 7129-7142. Date of Electronic Publication: 2025 Jun 16.

Publication Type: Journal Article

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101230060 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1549-960X (Electronic) Linking ISSN: 15499596 NLM ISO Abbreviation: J Chem Inf Model Subsets: MEDLINE

The evolving role of hydrogen/deuterium exchange mass spectrometry in early-stage drug discovery.

Authors: Krishnamurthy S Musgaard M Tehan BG et al.

Source: Current opinion in structural biology [Curr Opin Struct Biol] 2025 Jun; Vol. 92, pp. 103051. Date of Electronic Publication: 2025 May 02.

Publication Type: Journal Article; Review

Journal Info: Publisher: Elsevier Science Country of Publication: England NLM ID: 9107784 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-033X (Electronic) Linking ISSN: 0959440X NLM ISO Abbreviation: Curr Opin Struct Biol Subsets: MEDLINE

Statin activation of skeletal ryanodine receptors (RyR1) is a class effect but separable from HMG-CoA reductase inhibition.

Authors: Lindsay C Musgaard M Russell AJ et al.

Source: British journal of pharmacology [Br J Pharmacol] 2022 Nov; Vol. 179 (21), pp. 4941-4957. Date of Electronic Publication: 2022 Aug 02.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5381 (Electronic) Linking ISSN: 00071188 NLM ISO Abbreviation: Br J Pharmacol Subsets: MEDLINE

The V2475F CPVT1 mutation yields distinct RyR2 channel populations that differ in their responses to cytosolic Ca²⁺ and Mg².

Authors: Wilson AD Hu J Sigalas C et al.

Source: The Journal of physiology [J Physiol] 2021 Dec; Vol. 599 (23), pp. 5179-5201. Date of Electronic Publication: 2021 Nov 09.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Cambridge Univ. Press Country of Publication: England NLM ID: 0266262 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1469-7793 (Electronic) Linking ISSN: 00223751 NLM ISO Abbreviation: J Physiol Subsets: MEDLINE

Molecular Investigation of Chicken Acid-Sensing Ion Channel 1 β11-12 Linker Isomerization and Channel Kinetics.

Authors: Rook ML Ananchenko A Musgaard M et al.

Source: Frontiers in cellular neuroscience [Front Cell Neurosci] 2021 Nov 24; Vol. 15, pp. 761813. Date of Electronic Publication: 2021 Nov 24 (Print Publication: 2021).

Publication Type: Journal Article

Journal Info: Publisher: Frontiers Research Foundation Country of Publication: Switzerland NLM ID: 101477935 Publication Model: eCollection Cited Medium: Print ISSN: 1662-5102 (Print) Linking ISSN: 16625102 NLM ISO Abbreviation: Front Cell Neurosci Subsets: PubMed not MEDLINE

Coupling structure with function in acid-sensing ion channels: challenges in pursuit of proton sensors.

Authors: Rook ML Musgaard M MacLean DM

Source: The Journal of physiology [J Physiol] 2021 Jan; Vol. 599 (2), pp. 417-430. Date of Electronic Publication: 2020 May 20.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review

Journal Info: Publisher: Cambridge Univ. Press Country of Publication: England NLM ID: 0266262 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1469-7793 (Electronic) Linking ISSN: 00223751 NLM ISO Abbreviation: J Physiol Subsets: MEDLINE

Multiscale molecular dynamics simulations predict arachidonic acid binding sites in human ASIC1a and ASIC3 transmembrane domains.

Authors: Ananchenko A Musgaard M

Source: The Journal of general physiology [J Gen Physiol] 2023 Mar 06; Vol. 155 (3). Date of Electronic Publication: 2023 Jan 10.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Rockefeller University Press Country of Publication: United States NLM ID: 2985110R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1540-7748 (Electronic) Linking ISSN: 00221295 NLM ISO Abbreviation: J Gen Physiol Subsets: MEDLINE

Identification and functional evaluation of GRIA1 missense and truncation variants in individuals with ID: An emerging neurodevelopmental syndrome.

Authors: Ismail V Zachariassen LG Godwin A et al.

Source: American journal of human genetics [Am J Hum Genet] 2022 Jul 07; Vol. 109 (7), pp. 1217-1241. Date of Electronic Publication: 2022 Jun 07.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 0370475 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1537-6605 (Electronic) Linking ISSN: 00029297 NLM ISO Abbreviation: Am J Hum Genet Subsets: MEDLINE

Mutation of a conserved glutamine residue does not abolish desensitization of acid-sensing ion channel 1.

Authors: Rook ML Miaro M Couch T et al.

Source: The Journal of general physiology [J Gen Physiol] 2021 Aug 02; Vol. 153 (8). Date of Electronic Publication: 2021 Jun 01.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

Journal Info: Publisher: Rockefeller University Press Country of Publication: United States NLM ID: 2985110R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1540-7748 (Electronic) Linking ISSN: 00221295 NLM ISO Abbreviation: J Gen Physiol Subsets: MEDLINE

Kainate receptor pore-forming and auxiliary subunits regulate channel block by a novel mechanism.

Authors: Brown PM Aurousseau MR Musgaard M et al.

Source: The Journal of physiology [J Physiol] 2016 Apr 01; Vol. 594 (7), pp. 1821-40. Date of Electronic Publication: 2016 Feb 02.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Cambridge Univ. Press Country of Publication: England NLM ID: 0266262 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1469-7793 (Electronic) Linking ISSN: 00223751 NLM ISO Abbreviation: J Physiol Subsets: MEDLINE

A single historical substitution drives an increase in acetylcholine receptor complexity.

Authors: Emlaw JR Tessier CJG McCluskey GD et al.

Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2021 Feb 16; Vol. 118 (7).

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

Identification of compounds that bind the centriolar protein SAS-6 and inhibit its oligomerization.

Authors: Busch JMC Matsoukas MT Musgaard M et al.

Source: The Journal of biological chemistry [J Biol Chem] 2020 Dec 25; Vol. 295 (52), pp. 17922-17934. Date of Electronic Publication: 2020 Sep 01.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1083-351X (Electronic) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE

Actions of agonists, fipronil and ivermectin on the predominant in vivo splice and edit variant (RDLbd, I/V) of the Drosophila GABA receptor expressed in Xenopus laevis oocytes.

Authors: Lees K Musgaard M Suwanmanee S et al.

Source: PloS one [PLoS One] 2014 May 13; Vol. 9 (5), pp. e97468. Date of Electronic Publication: 2014 May 13 (Print Publication: 2014).

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

The dynamics of camphor in the cytochrome P450 CYP101D2.

Authors: Vohra S Musgaard M Bell SG et al.

Source: Protein science : a publication of the Protein Society [Protein Sci] 2013 Sep; Vol. 22 (9), pp. 1218-29. Date of Electronic Publication: 2013 Aug 12.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Cold Spring Harbor Laboratory Press Country of Publication: United States NLM ID: 9211750 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1469-896X (Electronic) Linking ISSN: 09618368 NLM ISO Abbreviation: Protein Sci Subsets: MEDLINE

Defining the structural relationship between kainate-receptor deactivation and desensitization.

Authors: Dawe GB Musgaard M Andrews ED et al.

Source: Nature structural & molecular biology [Nat Struct Mol Biol] 2013 Sep; Vol. 20 (9), pp. 1054-61. Date of Electronic Publication: 2013 Aug 18.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101186374 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1545-9985 (Electronic) Linking ISSN: 15459985 NLM ISO Abbreviation: Nat Struct Mol Biol Subsets: MEDLINE

β11-12 linker isomerization governs acid-sensing ion channel desensitization and recovery.

Authors: Rook ML Williamson A Lueck JD et al.

Source: ELife [Elife] 2020 Feb 07; Vol. 9. Date of Electronic Publication: 2020 Feb 07.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic Cited Medium: Internet ISSN: 2050-084X (Electronic) Linking ISSN: 2050084X NLM ISO Abbreviation: Elife Subsets: MEDLINE

Mutational Analysis and Modeling of Negative Allosteric Modulator Binding Sites in AMPA Receptors.

Authors: Stenum-Berg C Musgaard M Chavez-Abiega S et al.

Source: Molecular pharmacology [Mol Pharmacol] 2019 Dec; Vol. 96 (6), pp. 835-850. Date of Electronic Publication: 2019 Oct 03.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 0035623 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-0111 (Electronic) Linking ISSN: 0026895X NLM ISO Abbreviation: Mol Pharmacol Subsets: MEDLINE