Search Results - "Over B"

Mining Natural Products for Macrocycles to Drug Difficult Targets.

Authors: Begnini F Poongavanam V Over B et al.

Source: Journal of medicinal chemistry [J Med Chem] 2021 Jan 28; Vol. 64 (2), pp. 1054-1072. Date of Electronic Publication: 2020 Dec 18.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

Ca(2+) -related signaling events influence TLR9-induced IL-10 secretion in human B cells.

Authors: Ziegler S Gartner K Scheuermann U et al.

Source: European journal of immunology [Eur J Immunol] 2014 May; Vol. 44 (5), pp. 1285-98. Date of Electronic Publication: 2014 Feb 19.

Publication Type: Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 1273201 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-4141 (Electronic) Linking ISSN: 00142980 NLM ISO Abbreviation: Eur J Immunol Subsets: MEDLINE

IRAK4 turns IL-10+ phospho-FOXO+ monocytes into pro-inflammatory cells by suppression of protein kinase B.

Authors: Over B Ziegler S Foermer S et al.

Source: European journal of immunology [Eur J Immunol] 2013 Jun; Vol. 43 (6), pp. 1630-42. Date of Electronic Publication: 2013 Apr 30.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 1273201 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-4141 (Electronic) Linking ISSN: 00142980 NLM ISO Abbreviation: Eur J Immunol Subsets: MEDLINE

Natural-product-derived fragments for fragment-based ligand discovery.

Authors: Over B Wetzel S Grütter C et al.

Source: Nature chemistry [Nat Chem] 2013 Jan; Vol. 5 (1), pp. 21-8. Date of Electronic Publication: 2012 Dec 02.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101499734 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1755-4349 (Electronic) Linking ISSN: 17554330 NLM ISO Abbreviation: Nat Chem Subsets: MEDLINE

LytR-CpsA-Psr proteins in Staphylococcus aureus display partial functional redundancy and the deletion of all three severely impairs septum placement and cell separation.

Authors: Over B Heusser R McCallum N et al.

Source: FEMS microbiology letters [FEMS Microbiol Lett] 2011 Jul; Vol. 320 (2), pp. 142-51. Date of Electronic Publication: 2011 May 23.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 7705721 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1574-6968 (Electronic) Linking ISSN: 03781097 NLM ISO Abbreviation: FEMS Microbiol Lett Subsets: MEDLINE

Impact of Dynamically Exposed Polarity on Permeability and Solubility of Chameleonic Drugs Beyond the Rule of 5.

Authors: Rossi Sebastiano M Doak BC Backlund M et al.

Source: Journal of medicinal chemistry [J Med Chem] 2018 May 10; Vol. 61 (9), pp. 4189-4202. Date of Electronic Publication: 2018 Apr 16.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

Erratum: Structural and conformational determinants of macrocycle cell permeability.

Authors: Over B Matsson P Tyrchan C et al.

Source: Nature chemical biology [Nat Chem Biol] 2017 Jul 18; Vol. 13 (8), pp. 922.

Publication Type: Journal Article; Published Erratum

Journal Info: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101231976 Publication Model: Print Cited Medium: Internet ISSN: 1552-4469 (Electronic) Linking ISSN: 15524450 NLM ISO Abbreviation: Nat Chem Biol Subsets: PubMed not MEDLINE

Structural and conformational determinants of macrocycle cell permeability.

Authors: Over B Matsson P Tyrchan C et al.

Source: Nature chemical biology [Nat Chem Biol] 2016 Dec; Vol. 12 (12), pp. 1065-1074. Date of Electronic Publication: 2016 Oct 17.

Publication Type: Journal Article

Journal Info: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101231976 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1552-4469 (Electronic) Linking ISSN: 15524450 NLM ISO Abbreviation: Nat Chem Biol Subsets: MEDLINE

Cell permeability beyond the rule of 5.

Authors: Matsson P Doak BC Over B et al.

Source: Advanced drug delivery reviews [Adv Drug Deliv Rev] 2016 Jun 01; Vol. 101, pp. 42-61. Date of Electronic Publication: 2016 Apr 09.

Publication Type: Journal Article; Review

Journal Info: Publisher: Elsevier Science Publishers, B.V Country of Publication: Netherlands NLM ID: 8710523 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-8294 (Electronic) Linking ISSN: 0169409X NLM ISO Abbreviation: Adv Drug Deliv Rev Subsets: MEDLINE

Oral druggable space beyond the rule of 5: insights from drugs and clinical candidates.

Authors: Doak BC Over B Giordanetto F et al.

Source: Chemistry & biology [Chem Biol] 2014 Sep 18; Vol. 21 (9), pp. 1115-42.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Review

Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 9500160 Publication Model: Print Cited Medium: Internet ISSN: 1879-1301 (Electronic) Linking ISSN: 10745521 NLM ISO Abbreviation: Chem Biol Subsets: MEDLINE

Impact of stereospecific intramolecular hydrogen bonding on cell permeability and physicochemical properties.

Authors: Over B McCarren P Artursson P et al.

Source: Journal of medicinal chemistry [J Med Chem] 2014 Mar 27; Vol. 57 (6), pp. 2746-54. Date of Electronic Publication: 2014 Feb 26.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

Pathogen-triggered activation of plasmacytoid dendritic cells induces IL-10-producing B cells in response to Staphylococcus aureus.

Authors: Parcina M Miranda-Garcia MA Durlanik S et al.

Source: Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2013 Feb 15; Vol. 190 (4), pp. 1591-602. Date of Electronic Publication: 2013 Jan 16.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 2985117R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1550-6606 (Electronic) Linking ISSN: 00221767 NLM ISO Abbreviation: J Immunol Subsets: MEDLINE

In vivo expression profile of the antiviral restriction factor and tumor-targeting antigen CD317/BST-2/HM1.24/tetherin in humans.

Authors: Erikson E Adam T Schmidt S et al.

Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2011 Aug 16; Vol. 108 (33), pp. 13688-93. Date of Electronic Publication: 2011 Aug 01.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

Fragment-based lead discovery: screening and optimizing fragments for thermolysin inhibition.

Authors: Englert L Silber K Steuber H et al.

Source: ChemMedChem [ChemMedChem] 2010 Jun 07; Vol. 5 (6), pp. 930-40.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 101259013 Publication Model: Print Cited Medium: Internet ISSN: 1860-7187 (Electronic) Linking ISSN: 18607179 NLM ISO Abbreviation: ChemMedChem Subsets: MEDLINE