Search Results - "Overgaard RV"

Establishing Good Practices for Exposure-Response Analysis of Clinical Endpoints in Drug Development.

Authors: Overgaard, RV Ingwersen, SH Tornøe, CW

Source: CPT: Pharmacometrics & Systems Pharmacology. Oct2015, Vol. 4 Issue 10, p565-575. 11p.

Efficacy, Safety and PK of Once-Daily Oral Semaglutide 25 mg for Obesity With and Without Type 2 Diabetes in Comparison With Subcutaneous Semaglutide 2.4 mg: A Model-Informed Drug Development Approach.

Authors: Overgaard RV Birkhan O Rathor N et al.

Source: Diabetes, obesity & metabolism [Diabetes Obes Metab] 2026 Jul; Vol. 28 (7), pp. 5982-5991. Date of Electronic Publication: 2026 Apr 23.

Publication Type: Journal Article; Comparative Study

Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 100883645 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1463-1326 (Electronic) Linking ISSN: 14628902 NLM ISO Abbreviation: Diabetes Obes Metab Subsets: MEDLINE

The Impact of Missed Doses on Pharmacokinetic Concentrations for Oral Semaglutide in Comparison to Other Glucagon-Like Peptide-1-Based Therapies.

Authors: Overgaard RV Agersø H Hollensen C et al.

Source: Diabetes, obesity & metabolism [Diabetes Obes Metab] 2026 Jun 23. Date of Electronic Publication: 2026 Jun 23.

Publication Type: Letter

Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 100883645 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1463-1326 (Electronic) Linking ISSN: 14628902 NLM ISO Abbreviation: Diabetes Obes Metab Subsets: MEDLINE

Efficacy, Safety and Pharmacokinetics of Semaglutide 1.7 mg for Obesity Treatment in Adolescents: A Model-Informed Drug Development Approach.

Authors: Strathe A Bomberg EM Jensch G et al.

Source: Diabetes, obesity & metabolism [Diabetes Obes Metab] 2026 Jun; Vol. 28 (6), pp. 4926-4934. Date of Electronic Publication: 2026 Mar 30.

Publication Type: Journal Article; Randomized Controlled Trial

Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 100883645 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1463-1326 (Electronic) Linking ISSN: 14628902 NLM ISO Abbreviation: Diabetes Obes Metab Subsets: MEDLINE

A model-based approach to predict individual weight loss with semaglutide in people with overweight or obesity.

Authors: Strathe A Horn DB Larsen MS et al.

Source: Diabetes, obesity & metabolism [Diabetes Obes Metab] 2023 Nov; Vol. 25 (11), pp. 3171-3180. Date of Electronic Publication: 2023 Jul 09.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 100883645 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1463-1326 (Electronic) Linking ISSN: 14628902 NLM ISO Abbreviation: Diabetes Obes Metab Subsets: MEDLINE

Clinical Pharmacokinetics of Oral Semaglutide: Analyses of Data from Clinical Pharmacology Trials.

Authors: Overgaard RV Navarria A Ingwersen SH et al.

Source: Clinical pharmacokinetics [Clin Pharmacokinet] 2021 Oct; Vol. 60 (10), pp. 1335-1348. Date of Electronic Publication: 2021 May 10.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Adis, part of Springer Science+Business Media Country of Publication: Switzerland NLM ID: 7606849 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1179-1926 (Electronic) Linking ISSN: 03125963 NLM ISO Abbreviation: Clin Pharmacokinet Subsets: MEDLINE

Optimal Monitoring of Weekly IGF-I Levels During Growth Hormone Therapy With Once-Weekly Somapacitan.

Authors: Juul Kildemoes R Højby Rasmussen M Agersø H et al.

Source: The Journal of clinical endocrinology and metabolism [J Clin Endocrinol Metab] 2021 Jan 23; Vol. 106 (2), pp. 567-576.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Oxford University Press Country of Publication: United States NLM ID: 0375362 Publication Model: Print Cited Medium: Internet ISSN: 1945-7197 (Electronic) Linking ISSN: 0021972X NLM ISO Abbreviation: J Clin Endocrinol Metab Subsets: MEDLINE

Impact of dose-escalation schemes and drug discontinuation on weight loss outcomes with liraglutide 3.0 mg: A model-based approach.

Authors: Papathanasiou T Strathe A Agersø H et al.

Source: Diabetes, obesity & metabolism [Diabetes Obes Metab] 2020 Jun; Vol. 22 (6), pp. 969-977. Date of Electronic Publication: 2020 Feb 19.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 100883645 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1463-1326 (Electronic) Linking ISSN: 14628902 NLM ISO Abbreviation: Diabetes Obes Metab Subsets: MEDLINE

Optimizing Dose-Finding Studies for Drug Combinations Based on Exposure-Response Models.

Authors: Papathanasiou T Strathe A Overgaard RV et al.

Source: The AAPS journal [AAPS J] 2019 Jul 29; Vol. 21 (5), pp. 95. Date of Electronic Publication: 2019 Jul 29.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Association of Pharmaceutical Scientists Country of Publication: United States NLM ID: 101223209 Publication Model: Electronic Cited Medium: Internet ISSN: 1550-7416 (Electronic) Linking ISSN: 15507416 NLM ISO Abbreviation: AAPS J Subsets: MEDLINE

Pharmacokinetics and Pharmacodynamics of Once-Weekly Somapacitan in Children and Adults: Supporting Dosing Rationales with a Model-Based Analysis of Three Phase I Trials.

Authors: Juul RV Rasmussen MH Agersø H et al.

Source: Clinical pharmacokinetics [Clin Pharmacokinet] 2019 Jan; Vol. 58 (1), pp. 63-75.

Publication Type: Clinical Trial, Phase I; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Adis, part of Springer Science+Business Media Country of Publication: Switzerland NLM ID: 7606849 Publication Model: Print Cited Medium: Internet ISSN: 1179-1926 (Electronic) Linking ISSN: 03125963 NLM ISO Abbreviation: Clin Pharmacokinet Subsets: MEDLINE

Impact on HbA1c and body weight of switching from other GLP-1 receptor agonists to semaglutide: A model-based approach.

Authors: Overgaard RV Lindberg SØ Thielke D

Source: Diabetes, obesity & metabolism [Diabetes Obes Metab] 2019 Jan; Vol. 21 (1), pp. 43-51. Date of Electronic Publication: 2018 Aug 23.

Publication Type: Clinical Trial, Phase II; Clinical Trial, Phase III; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 100883645 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1463-1326 (Electronic) Linking ISSN: 14628902 NLM ISO Abbreviation: Diabetes Obes Metab

Exposure-response analysis for evaluation of semaglutide dose levels in type 2 diabetes.

Authors: Petri KCC Ingwersen SH Flint A et al.

Source: Diabetes, obesity & metabolism [Diabetes Obes Metab] 2018 Sep; Vol. 20 (9), pp. 2238-2245. Date of Electronic Publication: 2018 Jun 15.

Publication Type: Evaluation Study; Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 100883645 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1463-1326 (Electronic) Linking ISSN: 14628902 NLM ISO Abbreviation: Diabetes Obes Metab Subsets: MEDLINE

Feasibility of Exposure-Response Analyses for Clinical Dose-Ranging Studies of Drug Combinations.

Authors: Papathanasiou T Strathe A Hooker AC et al.

Source: The AAPS journal [AAPS J] 2018 Apr 23; Vol. 20 (3), pp. 64. Date of Electronic Publication: 2018 Apr 23.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Association of Pharmaceutical Scientists Country of Publication: United States NLM ID: 101223209 Publication Model: Electronic Cited Medium: Internet ISSN: 1550-7416 (Electronic) Linking ISSN: 15507416 NLM ISO Abbreviation: AAPS J Subsets: MEDLINE

Levels of circulating semaglutide determine reductions in HbA1c and body weight in people with type 2 diabetes.

Authors: Overgaard RV Hertz CL Ingwersen SH et al.

Source: Cell reports. Medicine [Cell Rep Med] 2021 Sep 03; Vol. 2 (9), pp. 100387. Date of Electronic Publication: 2021 Sep 03 (Print Publication: 2021).

Publication Type: Clinical Trial, Phase III; Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101766894 Publication Model: eCollection Cited Medium: Internet ISSN: 2666-3791 (Electronic) Linking ISSN: 26663791 NLM ISO Abbreviation: Cell Rep Med

Liraglutide 3.0 mg for Weight Management: A Population Pharmacokinetic Analysis.

Authors: Overgaard RV Petri KC Jacobsen LV et al.

Source: Clinical pharmacokinetics [Clin Pharmacokinet] 2016 Nov; Vol. 55 (11), pp. 1413-1422.

Publication Type: Clinical Trial, Phase II; Clinical Trial, Phase III; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Adis, part of Springer Science+Business Media Country of Publication: Switzerland NLM ID: 7606849 Publication Model: Print Cited Medium: Internet ISSN: 1179-1926 (Electronic) Linking ISSN: 03125963 NLM ISO Abbreviation: Clin Pharmacokinet Subsets: MEDLINE

Exposure-response analyses of liraglutide 3.0 mg for weight management.

Authors: Wilding JP Overgaard RV Jacobsen LV et al.

Source: Diabetes, obesity & metabolism [Diabetes Obes Metab] 2016 May; Vol. 18 (5), pp. 491-9. Date of Electronic Publication: 2016 Mar 01.

Publication Type: Clinical Trial, Phase II; Clinical Trial, Phase III; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 100883645 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1463-1326 (Electronic) Linking ISSN: 14628902 NLM ISO Abbreviation: Diabetes Obes Metab Subsets: MEDLINE

Clinical pharmacokinetics of the anti-interleukin-20 monoclonal antibody NNC0109-0012 in healthy volunteers and patients with psoriasis or rheumatoid arthritis.

Authors: Lundblad MS Overgaard RV Göthberg M et al.

Source: Advances in therapy [Adv Ther] 2015 Mar; Vol. 32 (3), pp. 228-38. Date of Electronic Publication: 2015 Mar 07.

Publication Type: Clinical Trial, Phase I; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Health Communications Inc Country of Publication: United States NLM ID: 8611864 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1865-8652 (Electronic) Linking ISSN: 0741238X NLM ISO Abbreviation: Adv Ther

Body composition is the main determinant for the difference in type 2 diabetes pathophysiology between Japanese and Caucasians.

Authors: Møller JB Pedersen M Tanaka H et al.

Source: Diabetes care [Diabetes Care] 2014; Vol. 37 (3), pp. 796-804. Date of Electronic Publication: 2013 Oct 15.

Publication Type: Clinical Trial; Journal Article; Multicenter Study

Journal Info: Publisher: American Diabetes Association Country of Publication: United States NLM ID: 7805975 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1935-5548 (Electronic) Linking ISSN: 01495992 NLM ISO Abbreviation: Diabetes Care Subsets: MEDLINE

Mechanism-based population modelling for assessment of L-cell function based on total GLP-1 response following an oral glucose tolerance test.

Authors: Møller JB Jusko WJ Gao W et al.

Source: Journal of pharmacokinetics and pharmacodynamics [J Pharmacokinet Pharmacodyn] 2011 Dec; Vol. 38 (6), pp. 713-25. Date of Electronic Publication: 2011 Sep 16.

Publication Type: Journal Article; Research Support, N.I.H., Extramural

Journal Info: Publisher: Springer Country of Publication: United States NLM ID: 101096520 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-8744 (Electronic) Linking ISSN: 1567567X NLM ISO Abbreviation: J Pharmacokinet Pharmacodyn Subsets: MEDLINE

An integrated disease/pharmacokinetic/pharmacodynamic model suggests improved interleukin-21 regimens validated prospectively for mouse solid cancers.

Authors: Elishmereni M Kheifetz Y Søndergaard H et al.

Source: PLoS computational biology [PLoS Comput Biol] 2011 Sep; Vol. 7 (9), pp. e1002206. Date of Electronic Publication: 2011 Sep 29.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238922 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1553-7358 (Electronic) Linking ISSN: 1553734X NLM ISO Abbreviation: PLoS Comput Biol Subsets: MEDLINE