Search Results - "Pandher, Ruby"

The cell-permeable iron chelator M606 inhibits MYCN-driven neuroblastoma via an E2F3-mediated response.

Authors: Pandher, Ruby Chengyuan Xue Gamble, Laura D. et al.

Source: Proceedings of the National Academy of Sciences of the United States of America. 6/10/2025, Vol. 122 Issue 23, p1-12. 31p.

Subjects: Transcription factors, Hypoxia-inducible factor 1, Myc proteins, Iron chelates, Childhood cancer

Arginine depletion potentiates standard-of-care chemo-immunotherapy in preclinical models of high-risk neuroblastoma.

Authors: Hanssen, Kimberley M. Murray, Jayne Pandher, Ruby et al.

Source: Journal of Experimental & Clinical Cancer Research (17569966). 8/14/2025, Vol. 44 Issue 1, p1-16. 16p.

Combined inhibition of histone methyltransferases EZH2 and DOT1L is an effective therapy for neuroblastoma.

Authors: Seneviratne, Janith A. Ravindrarajah, Daenikka Carter, Daniel R. et al.

Source: Cancer Medicine. Nov2024, Vol. 13 Issue 21, p1-20. 20p.

Direct targeted therapy for MLL‐fusion‐driven high‐risk acute leukaemias.

Authors: Cantilena, Sandra Gasparoli, Luca Pal, Deepali et al.

Source: Clinical & Translational Medicine. Jun2022, Vol. 12 Issue 6, p1-19. 19p.

High-throughput in vitro drug screening and in vivo studies identify fenretinide as a brain-penetrant DMG therapeutic.

Authors: Upton DH Liu J George SM et al.

Source: Neuro-oncology [Neuro Oncol] 2025 Sep 08; Vol. 27 (7), pp. 1813-1828.

Publication Type: Journal Article

Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 100887420 Publication Model: Print Cited Medium: Internet ISSN: 1523-5866 (Electronic) Linking ISSN: 15228517 NLM ISO Abbreviation: Neuro Oncol Subsets: MEDLINE

The polyamine transporter ATP13A3 mediates difluoromethylornithine-induced polyamine uptake in neuroblastoma.

Authors: Azfar M Gao W Van den Haute C et al.

Source: Molecular oncology [Mol Oncol] 2025 Mar; Vol. 19 (3), pp. 913-936. Date of Electronic Publication: 2025 Feb 21.

Publication Type: Journal Article

Journal Info: Publisher: John Wiley & Sons, Inc Country of Publication: United States NLM ID: 101308230 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-0261 (Electronic) Linking ISSN: 15747891 NLM ISO Abbreviation: Mol Oncol Subsets: MEDLINE

Dual targeting of polyamine synthesis and uptake in diffuse intrinsic pontine gliomas.

Authors: Khan A Gamble LD Upton DH et al.

Source: Nature communications [Nat Commun] 2021 Feb 12; Vol. 12 (1), pp. 971. Date of Electronic Publication: 2021 Feb 12.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

Dual Targeting of Chromatin Stability By The Curaxin CBL0137 and Histone Deacetylase Inhibitor Panobinostat Shows Significant Preclinical Efficacy in Neuroblastoma.

Authors: Xiao L Somers K Murray J et al.

Source: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2021 Aug 01; Vol. 27 (15), pp. 4338-4352. Date of Electronic Publication: 2021 May 16.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 9502500 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1557-3265 (Electronic) Linking ISSN: 10780432 NLM ISO Abbreviation: Clin Cancer Res Subsets: MEDLINE

Dual targeting of the epigenome via FACT complex and histone deacetylase is a potent treatment strategy for DIPG.

Authors: Ehteda A Simon S Franshaw L et al.

Source: Cell reports [Cell Rep] 2021 Apr 13; Vol. 35 (2), pp. 108994.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE

A novel small molecule that kills a subset of MLL-rearranged leukemia cells by inducing mitochondrial dysfunction.

Authors: Somers K Wen VW Middlemiss SMC et al.

Source: Oncogene [Oncogene] 2019 May; Vol. 38 (20), pp. 3824-3842. Date of Electronic Publication: 2019 Jan 22.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5594 (Electronic) Linking ISSN: 09509232 NLM ISO Abbreviation: Oncogene Subsets: MEDLINE