Search Results - "Petrassi HM"

SuFEx-based antitubercular compound irreversibly inhibits Pks13.

Authors: Krieger IV Sukheja P Yang B et al.

Source: Nature [Nature] 2025 Sep; Vol. 645 (8081), pp. 755-763. Date of Electronic Publication: 2025 Jul 30.

Publication Type: Journal Article; Research Support, N.I.H., Extramural

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE

Integrating chemical, genetic, and feasibility assessments for anti-tubercular target validation.

Authors: Schnappinger D Berthel SJ Boshoff HIM et al.

Source: EMBO molecular medicine [EMBO Mol Med] 2026 May; Vol. 18 (5), pp. 1495-1507. Date of Electronic Publication: 2026 Apr 07.

Publication Type: Journal Article; Review

Journal Info: Publisher: EMBO Press Country of Publication: Germany NLM ID: 101487380 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1757-4684 (Electronic) Linking ISSN: 17574676 NLM ISO Abbreviation: EMBO Mol Med Subsets: MEDLINE

Inhibitors of NADH-O-methylquinone compound a class of antitubercular drugs.

Authors: Lin D Xu C Gan C et al.

Source: Molecular diversity [Mol Divers] 2025 Dec; Vol. 29 (6), pp. 5823-5833. Date of Electronic Publication: 2025 Jan 25.

Publication Type: Journal Article

Journal Info: Publisher: ESCOM Science Publishers Country of Publication: Netherlands NLM ID: 9516534 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-501X (Electronic) Linking ISSN: 13811991 NLM ISO Abbreviation: Mol Divers Subsets: MEDLINE

Pharmacological and genetic activation of cAMP synthesis disrupts cholesterol utilization in Mycobacterium tuberculosis.

Authors: Wilburn KM Montague CR Qin B et al.

Source: PLoS pathogens [PLoS Pathog] 2022 Feb 08; Vol. 18 (2), pp. e1009862. Date of Electronic Publication: 2022 Feb 08 (Print Publication: 2022).

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7374 (Electronic) Linking ISSN: 15537366 NLM ISO Abbreviation: PLoS Pathog Subsets: MEDLINE

Intrinsic STING of CD8 + T cells regulates self-metabolic reprogramming and memory to exert anti-tumor effects.

Authors: Xu, Qiuli Hua, Xin Li, Bingbing et al.

Source: Cell Communication & Signaling. 2/19/2025, Vol. 23 Issue 1, p1-18. 18p.

Effect of Mechanically Activated Calcium Channels on Passive Stiffness and Contraction Amplitude of Slow Muscle.

Authors: Sergeeva, K. V. Tyganov, S. A. Zaripova, K. A. et al.

Source: Journal of Evolutionary Biochemistry & Physiology. Jan2025, Vol. 61 Issue 1, p115-121. 7p.

Melatonin and mitochondrial protection in cardiac ischemia-reperfusion injury: mechanisms, evidence and translational perspectives.

Authors: Pedriali G Leo S Tiezzi M et al.

Source: Basic research in cardiology [Basic Res Cardiol] 2026 Apr; Vol. 121 (2), pp. 153-185. Date of Electronic Publication: 2026 Feb 24.

Publication Type: Journal Article; Review

Journal Info: Publisher: Steinkopff Country of Publication: Germany NLM ID: 0360342 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1435-1803 (Electronic) Linking ISSN: 03008428 NLM ISO Abbreviation: Basic Res Cardiol Subsets: MEDLINE

Synthesis and structure-activity relationships of aryl fluorosulfate-based inhibitors as novel antitubercular agents.

Authors: Yang B Sukheja P Qin B et al.

Source: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2024 Jan 15; Vol. 98, pp. 129596. Date of Electronic Publication: 2023 Dec 23.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 9107377 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1464-3405 (Electronic) Linking ISSN: 0960894X NLM ISO Abbreviation: Bioorg Med Chem Lett Subsets: MEDLINE

Transthyretin Kinetic Stabilizers for ATTR Amyloidosis: A Narrative Review of Mechanisms and Therapeutic Benefits.

Authors: Powers, Evan T. Amass, Leslie Baylor, Lori et al.

Source: Cardiology & Therapy. Sep2025, Vol. 14 Issue 3, p333-350. 18p.

Structural Insights into the Protein Mannosyltransferase from Mycobacterium tuberculosis reveal a WW-Domain-Like Protein Motif in Bacteria.

Authors: Géraud, Nicolas Rivière, Chloé Falcou, Camille et al.

Source: Communications Biology. 8/7/2025, Vol. 8 Issue 1, p1-18. 18p.

Pharmacological stabilization of the native state of full-length immunoglobulin light chains to treat light chain amyloidosis.

Authors: Yan NL Morgan GJ Petrassi HM et al.

Source: Current opinion in chemical biology [Curr Opin Chem Biol] 2023 Aug; Vol. 75, pp. 102319. Date of Electronic Publication: 2023 Jun 06.

Publication Type: Journal Article; Review; Research Support, N.I.H., Extramural

Journal Info: Publisher: Elsevier Country of Publication: England NLM ID: 9811312 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0402 (Electronic) Linking ISSN: 13675931 NLM ISO Abbreviation: Curr Opin Chem Biol Subsets: MEDLINE

Combination strategies targeting multiple ETC subunits as a rational approach for drug-resistant TB therapy.

Authors: Sau S Agnivesh PK Roy A et al.

Source: Archives of microbiology [Arch Microbiol] 2026 May 25; Vol. 208 (8). Date of Electronic Publication: 2026 May 25.

Publication Type: Journal Article; Review

Journal Info: Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 0410427 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-072X (Electronic) Linking ISSN: 03028933 NLM ISO Abbreviation: Arch Microbiol Subsets: MEDLINE

Deformability of Heterogeneous Red Blood Cells in Aging and Related Pathologies.

Authors: Prudinnik, Dmitry S. Kussanova, Aigul Vorobjev, Ivan A. et al.

Source: Aging & Disease. May2025, Vol. 16 Issue 3, p1242-1264. 23p.

Cellular Target Deconvolution of Small Molecules Using a Selection-Based Genetic Screening Platform.

Authors: Zhao J Tang Z Selvaraju M et al.

Source: ACS central science [ACS Cent Sci] 2022 Oct 26; Vol. 8 (10), pp. 1424-1434. Date of Electronic Publication: 2022 Sep 22.

Publication Type: Journal Article

Journal Info: Publisher: ACS Publications Country of Publication: United States NLM ID: 101660035 Publication Model: Print-Electronic Cited Medium: Print ISSN: 2374-7943 (Print) Linking ISSN: 23747943 NLM ISO Abbreviation: ACS Cent Sci Subsets: PubMed not MEDLINE

Characterising diflunisal as a transthyretin kinetic stabilizer at relevant concentrations in human plasma using subunit exchange.

Authors: Tsai, Felix J. Nelson, Luke T. Kline, Gabriel M. et al.

Source: Amyloid. Jun2023, Vol. 30 Issue 2, p220-224. 5p.

Discovery of repurposing drug candidates for the treatment of diseases caused by pathogenic free-living amoebae.

Authors: Rice, Christopher A. Colon, Beatrice L. Chen, Emily et al.

Source: PLoS Neglected Tropical Diseases. 9/24/2020, Vol. 14 Issue 9, p1-21. 21p.

Enhanced stabilisation and reduced fibril forming potential of an amyloidogenic light chain using a variable heavy domain to mimic the homodimer complex.

Authors: Maerivoet, Alana Price, Rebecca Galmiche, Cécile et al.

Source: FEBS Journal. Nov2024, Vol. 291 Issue 22, p4913-4929. 17p.

Transthyretin Glu54Leu - an unknown mutation within the Swedish population associated with amyloid cardiomyopathy and a unique fibril type.

Authors: Hellman, Urban Lång, Kenneth Ihse, Elisabet et al.

Source: Scandinavian Journal of Clinical & Laboratory Investigation. Oct2019, Vol. 79 Issue 6, p372-376. 5p.

Novel dual-targeting c-Myc inhibitor D347-2761 represses myeloma growth via blocking c-Myc/Max heterodimerization and disturbing its stability.

Authors: Yao, Ruosi Zhang, Menghui Zhou, Jian et al.

Source: Cell Communication & Signaling. 5/26/2022, Vol. 20 Issue 1, p1-16. 16p.

Piezo2 is not an indispensable mechanosensor in murine cardiomyocytes.

Authors: Kloth, Benjamin Mearini, Giulia Weinberger, Florian et al.

Source: Scientific Reports. 5/17/2022, Vol. 12 Issue 1, p1-12. 12p.