Search Results - "Pierson JB"

Detection of seizurogenic compounds in human and rat neurons in vitro: a multi-laboratory, multi-model assessment.

Authors: Roberts R Blinova K Carlson C et al.

Source: Neurotoxicology [Neurotoxicology] 2026 Jul 13, pp. 103519. Date of Electronic Publication: 2026 Jul 13.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 7905589 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-9711 (Electronic) Linking ISSN: 0161813X NLM ISO Abbreviation: Neurotoxicology Subsets: MEDLINE

Evaluation of Biomarkers to Detect Early Prothrombotic Imbalance in Rat Models of Hypercoagulability Induced by Thromboplastin Infusion and Hypofibrinolysis Induced by Tranexamic Acid.

Authors: Brooks MB Fishman CE Kamalakannan M et al.

Source: Toxicologic pathology [Toxicol Pathol] 2025 Oct; Vol. 53 (7), pp. 588-601. Date of Electronic Publication: 2025 Jul 15.

Publication Type: Journal Article

Journal Info: Publisher: Sage Publications Country of Publication: United States NLM ID: 7905907 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1533-1601 (Electronic) Linking ISSN: 01926233 NLM ISO Abbreviation: Toxicol Pathol Subsets: MEDLINE

Revisiting ICH S7A after 25 years: Outcomes of a multi-stakeholder workshop and strategic pillars for modernizing safety pharmacology.

Authors: Valentin JP Beken S Kanda Y et al.

Source: Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2026 Aug; Vol. 169, pp. 106096. Date of Electronic Publication: 2026 Apr 09.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8214983 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-0295 (Electronic) Linking ISSN: 02732300 NLM ISO Abbreviation: Regul Toxicol Pharmacol Subsets: MEDLINE

An overview of drug-induced sodium channel blockade and changes in cardiac conduction: Implications for drug safety.

Authors: Chaudhary KW Clancy CE Yang PC et al.

Source: Clinical and translational science [Clin Transl Sci] 2024 Dec; Vol. 17 (12), pp. e70098.

Publication Type: Journal Article; Review

Journal Info: Publisher: WileyBlackwell Pub Country of Publication: United States NLM ID: 101474067 Publication Model: Print Cited Medium: Internet ISSN: 1752-8062 (Electronic) Linking ISSN: 17528054 NLM ISO Abbreviation: Clin Transl Sci Subsets: MEDLINE

Use of new approach methodologies (NAMs) in epilepsy research and seizure risk assessment.

Authors: Roberts RA Behl M Hogberg HT et al.

Source: Drug discovery today [Drug Discov Today] 2026 Jan; Vol. 31 (1), pp. 104569. Date of Electronic Publication: 2025 Dec 03.

Publication Type: Journal Article; Review

Journal Info: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 9604391 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-5832 (Electronic) Linking ISSN: 13596446 NLM ISO Abbreviation: Drug Discov Today Subsets: MEDLINE

Validating and Using Cardiac NAMs for Toxicity Screening and Drug Development.

Authors: Pierson JB Bahinski A Berridge B et al.

Source: International journal of toxicology [Int J Toxicol] 2025 Nov-Dec; Vol. 44 (6), pp. 499-506. Date of Electronic Publication: 2025 Sep 09.

Publication Type: Journal Article; Review; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

Journal Info: Publisher: Sage Publications Country of Publication: United States NLM ID: 9708436 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1092-874X (Electronic) Linking ISSN: 10915818 NLM ISO Abbreviation: Int J Toxicol Subsets: MEDLINE

Multi-laboratory comparisons of manual patch clamp hERG data generated using standardized protocols and following ICH S7B Q&A 2.1 best practices.

Authors: Alvarez Baron C Zhao J Yu H et al.

Source: Scientific reports [Sci Rep] 2025 Aug 16; Vol. 15 (1), pp. 29995. Date of Electronic Publication: 2025 Aug 16.

Publication Type: Journal Article; Comparative Study

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

Detection of contractility changes in the heart from arterial blood pressure data using symmetric Projection Attractor Reconstruction.

Authors: Bonet-Luz E Nandi M Christie MI et al.

Source: Journal of pharmacological and toxicological methods [J Pharmacol Toxicol Methods] 2024 Sep-Oct; Vol. 129, pp. 107546. Date of Electronic Publication: 2024 Jul 26.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 9206091 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-488X (Electronic) Linking ISSN: 10568719 NLM ISO Abbreviation: J Pharmacol Toxicol Methods Subsets: MEDLINE

Collaborative science in action: A 20 year perspective from the Health and Environmental Sciences Institute (HESI) Cardiac Safety Committee.

Authors: Pierson JB Berridge B Blinova K et al.

Source: Journal of pharmacological and toxicological methods [J Pharmacol Toxicol Methods] 2024 May-Jun; Vol. 127, pp. 107511. Date of Electronic Publication: 2024 May 06.

Publication Type: Journal Article; Review

Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 9206091 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-488X (Electronic) Linking ISSN: 10568719 NLM ISO Abbreviation: J Pharmacol Toxicol Methods Subsets: MEDLINE

Can We Panelize Seizure?

Authors: Roberts R Authier S Mellon RD et al.

Source: Toxicological sciences : an official journal of the Society of Toxicology [Toxicol Sci] 2021 Jan 06; Vol. 179 (1), pp. 3-13.

Publication Type: Journal Article

Journal Info: Publisher: Oxford University Press Country of Publication: United States NLM ID: 9805461 Publication Model: Print Cited Medium: Internet ISSN: 1096-0929 (Electronic) Linking ISSN: 10960929 NLM ISO Abbreviation: Toxicol Sci Subsets: MEDLINE

Considerations for an In Vitro, Cell-Based Testing Platform for Detection of Drug-Induced Inotropic Effects in Early Drug Development. Part 2: Designing and Fabricating Microsystems for Assaying Cardiac Contractility With Physiological Relevance Using Human iPSC-Cardiomyocytes.

Authors: Ribeiro AJS Guth BD Engwall M et al.

Source: Frontiers in pharmacology [Front Pharmacol] 2019 Aug 29; Vol. 10, pp. 934. Date of Electronic Publication: 2019 Aug 29 (Print Publication: 2019).

Publication Type: Journal Article; Review

Journal Info: Publisher: Frontiers Media] Country of Publication: Switzerland NLM ID: 101548923 Publication Model: eCollection Cited Medium: Print ISSN: 1663-9812 (Print) Linking ISSN: 16639812 NLM ISO Abbreviation: Front Pharmacol Subsets: PubMed not MEDLINE

Considerations for an In Vitro, Cell-Based Testing Platform for Detection of Adverse Drug-Induced Inotropic Effects in Early Drug Development. Part 1: General Considerations for Development of Novel Testing Platforms.

Authors: Guth BD Engwall M Eldridge S et al.

Source: Frontiers in pharmacology [Front Pharmacol] 2019 Aug 09; Vol. 10, pp. 884. Date of Electronic Publication: 2019 Aug 09 (Print Publication: 2019).

Publication Type: Journal Article; Review

Journal Info: Publisher: Frontiers Media] Country of Publication: Switzerland NLM ID: 101548923 Publication Model: eCollection Cited Medium: Print ISSN: 1663-9812 (Print) Linking ISSN: 16639812 NLM ISO Abbreviation: Front Pharmacol Subsets: PubMed not MEDLINE

The incidence of spontaneous arrhythmias in telemetered beagle dogs, Göttingen Minipigs and Cynomolgus non-human primates: A HESI consortium retrospective analysis.

Authors: Boulay E Miraucourt LS Pugsley MK et al.

Source: Journal of pharmacological and toxicological methods [J Pharmacol Toxicol Methods] 2023 May-Jun; Vol. 121, pp. 107266. Date of Electronic Publication: 2023 Mar 22.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 9206091 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-488X (Electronic) Linking ISSN: 10568719 NLM ISO Abbreviation: J Pharmacol Toxicol Methods Subsets: MEDLINE

Can non-clinical repolarization assays predict the results of clinical thorough QT studies? Results from a research consortium.

Authors: Park E Gintant GA Bi D et al.

Source: British journal of pharmacology [Br J Pharmacol] 2018 Feb; Vol. 175 (4), pp. 606-617. Date of Electronic Publication: 2018 Jan 15.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5381 (Electronic) Linking ISSN: 00071188 NLM ISO Abbreviation: Br J Pharmacol Subsets: MEDLINE

Non-Lethal Endotoxin Injection: A Rat Model of Hypercoagulability.

Authors: Brooks MB Turk JR Guerrero A et al.

Source: PloS one [PLoS One] 2017 Jan 12; Vol. 12 (1), pp. e0169976. Date of Electronic Publication: 2017 Jan 12 (Print Publication: 2017).

Publication Type: Journal Article

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

Use of the ZDF rat to model dietary fat induced hypercoagulability is limited by progressive and fatal nephropathy.

Authors: Pugsley MK Brooks MB Fishman CE et al.

Source: Journal of pharmacological and toxicological methods [J Pharmacol Toxicol Methods] 2021 Jan-Feb; Vol. 107, pp. 106933. Date of Electronic Publication: 2020 Oct 27.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 9206091 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-488X (Electronic) Linking ISSN: 10568719 NLM ISO Abbreviation: J Pharmacol Toxicol Methods Subsets: MEDLINE

Repolarization studies using human stem cell-derived cardiomyocytes: Validation studies and best practice recommendations.

Authors: Gintant G Kaushik EP Feaster T et al.

Source: Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2020 Nov; Vol. 117, pp. 104756. Date of Electronic Publication: 2020 Aug 19.

Publication Type: Journal Article; Review

Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8214983 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-0295 (Electronic) Linking ISSN: 02732300 NLM ISO Abbreviation: Regul Toxicol Pharmacol Subsets: MEDLINE

Echocardiographic and hemodynamic indices of myocardial contractility simultaneously evaluated in telemetered beagle dogs: A HESI-sponsored cross-company evaluation.

Authors: Rossman EI Cools F Cordes J et al.

Source: Journal of pharmacological and toxicological methods [J Pharmacol Toxicol Methods] 2020 Sep; Vol. 105, pp. 106897. Date of Electronic Publication: 2020 Jul 12.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 9206091 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-488X (Electronic) Linking ISSN: 10568719 NLM ISO Abbreviation: J Pharmacol Toxicol Methods Subsets: MEDLINE

Evaluating uncertainty to strengthen epidemiologic data for use in human health risk assessments.

Authors: Burns CJ Wright JM Pierson JB et al.

Source: Environmental health perspectives [Environ Health Perspect] 2014 Nov; Vol. 122 (11), pp. 1160-5. Date of Electronic Publication: 2014 Jul 31.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: National Institute of Environmental Health Sciences Country of Publication: United States NLM ID: 0330411 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1552-9924 (Electronic) Linking ISSN: 00916765 NLM ISO Abbreviation: Environ Health Perspect Subsets: MEDLINE

Public health laboratories and radiological readiness.

Authors: Latshaw MW Mangal C Barkey A et al.

Source: Disaster medicine and public health preparedness [Disaster Med Public Health Prep] 2011 Oct; Vol. 5 (3), pp. 213-7. Date of Electronic Publication: 2011 Oct 10.

Publication Type: Journal Article

Journal Info: Publisher: Cambridge University Press Country of Publication: United States NLM ID: 101297401 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1938-744X (Electronic) Linking ISSN: 19357893 NLM ISO Abbreviation: Disaster Med Public Health Prep Subsets: MEDLINE