Search Results - "Protein engineering"

Engineering of ω-transaminases for advanced applications.

Authors: Wegner U von Wirén N Kunze G

Source: Applied microbiology and biotechnology [Appl Microbiol Biotechnol] 2026 Jun 04; Vol. 110 (1). Date of Electronic Publication: 2026 Jun 04.

Publication Type: Journal Article; Review

Journal Info: Publisher: Springer International Country of Publication: Germany NLM ID: 8406612 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-0614 (Electronic) Linking ISSN: 01757598 NLM ISO Abbreviation: Appl Microbiol Biotechnol Subsets: MEDLINE

Membrane protein solubilization and structure determination using de novo-designed proteins.

Authors: Mihaljević L Kim DE Bandawane PD et al.

Source: Science (New York, N.Y.) [Science] 2026 Jul 02; Vol. 393 (6806), pp. eadr3817. Date of Electronic Publication: 2026 Jul 02.

Publication Type: Journal Article

Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE

Bioinformatics classification of the MgtE Mg ^{2 +} protein design for the stabilization of its novel subclass.de novo protein design for the stabilization of its novel subclass.

Authors: Zhao Z Omae K Iwasaki W et al.

Source: Acta biochimica et biophysica Sinica [Acta Biochim Biophys Sin (Shanghai)] 2026 Jun 25; Vol. 58 (6), pp. 1402-1412.

Publication Type: Journal Article

Journal Info: Publisher: China Science Publishing & Media Ltd Country of Publication: China NLM ID: 101206716 Publication Model: Print Cited Medium: Internet ISSN: 1745-7270 (Electronic) Linking ISSN: 16729145 NLM ISO Abbreviation: Acta Biochim Biophys Sin (Shanghai) Subsets: MEDLINE

Engineered antibodies bypass bacterial immune evasion to drive complement-mediated protection against lethal infections.

Authors: Ali YM Yabuki M Arachchilage CH et al.

Source: Science translational medicine [Sci Transl Med] 2026 Jun 17; Vol. 18 (854), pp. eadx4108. Date of Electronic Publication: 2026 Jun 17.

Publication Type: Journal Article

Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE

Heuristic multi-site optimization for protein sequence design using Masked Protein Language Models.

Authors: Wang L Wang Y Qiu C et al.

Source: PLoS computational biology [PLoS Comput Biol] 2026 Jun 05; Vol. 22 (6), pp. e1014365. Date of Electronic Publication: 2026 Jun 05 (Print Publication: 2026).

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238922 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7358 (Electronic) Linking ISSN: 1553734X NLM ISO Abbreviation: PLoS Comput Biol Subsets: MEDLINE

Fast analysis and engineering of protein function by microbe-independent deep assembly and screening.

Authors: Wu Y Wang P Liu LX et al.

Source: Molecular systems biology [Mol Syst Biol] 2026 Jun; Vol. 22 (6), pp. 1003-1034. Date of Electronic Publication: 2026 Apr 23.

Publication Type: Journal Article

Journal Info: Publisher: EMBO Press Country of Publication: Germany NLM ID: 101235389 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1744-4292 (Electronic) Linking ISSN: 17444292 NLM ISO Abbreviation: Mol Syst Biol Subsets: MEDLINE

Scaffold-Lab: Critical evaluation and ranking of protein backbone generation methods in a unified framework.

Authors: Zheng Z Zhang B Zhong B et al.

Source: PLoS computational biology [PLoS Comput Biol] 2026 May 22; Vol. 22 (5), pp. e1014290. Date of Electronic Publication: 2026 May 22 (Print Publication: 2026).

Publication Type: Journal Article

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238922 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7358 (Electronic) Linking ISSN: 1553734X NLM ISO Abbreviation: PLoS Comput Biol Subsets: MEDLINE

Engineering strategies and binding mechanisms of therapeutic anti-PD-1 antibodies approved by regulatory agencies globally.

Authors: Almagro JC Gómez-Castellano K Licona-Limón I et al.

Source: Frontiers in immunology [Front Immunol] 2026 May 21; Vol. 17, pp. 1834585. Date of Electronic Publication: 2026 May 21 (Print Publication: 2026).

Publication Type: Journal Article; Review

Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE

Computational engineering of the polyester hydrolase PHL7 for efficient poly(ethylene terephthalate) degradation in biocatalytic recycling processes.

Authors: Blázquez-Sánchez P Gunkel J Useini A et al.

Source: Nature communications [Nat Commun] 2026 May 15; Vol. 17 (1). Date of Electronic Publication: 2026 May 15.

Publication Type: Journal Article

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

Building an oral peptide drug.

Authors: Buller R Pelletier JN

Source: Science (New York, N.Y.) [Science] 2026 May 07; Vol. 392 (6798), pp. 582-583. Date of Electronic Publication: 2026 May 07.

Publication Type: Journal Article; Comment

Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE

Rapid directed evolution guided by protein language models and epistatic interactions.

Authors: Tran VQ Nemeth M Bartie LJ et al.

Source: Science (New York, N.Y.) [Science] 2026 May 07; Vol. 392 (6798), pp. eaea1820. Date of Electronic Publication: 2026 May 07.

Publication Type: Journal Article

Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE

From atoms to fragments: a coarse representation for efficient and functional protein design.

Authors: Castorina LV Wood CW Subr K

Source: Bioinformatics (Oxford, England) [Bioinformatics] 2026 May 03; Vol. 42 (5).

Publication Type: Journal Article

Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 9808944 Publication Model: Print Cited Medium: Internet ISSN: 1367-4811 (Electronic) Linking ISSN: 13674803 NLM ISO Abbreviation: Bioinformatics Subsets: MEDLINE

Engineering of 10-Deacetylbaccatin III-10-β-O-Acetyltransferase From Taxus Species for Efficient Acetylating Non-Natural Substrates Into Taxol in Nicotiana benthamiana.

Authors: Chen TJ Chen JJ Sun XY et al.

Source: Plant biotechnology journal [Plant Biotechnol J] 2026 May; Vol. 24 (5), pp. 3308-3323. Date of Electronic Publication: 2026 Jan 30.

Publication Type: Journal Article

Journal Info: Publisher: Wiley on behalf of the Society for Experimental Biology, Association of Applied Biologists Country of Publication: England NLM ID: 101201889 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1467-7652 (Electronic) Linking ISSN: 14677644 NLM ISO Abbreviation: Plant Biotechnol J Subsets: MEDLINE

Characterization of the Orphan Cytochrome P450 CYP107J1 From Bacillus subtilis Through Peroxygenase Activity Engineering.

Authors: Kato H Hashimoto T Das T et al.

Source: Microbial biotechnology [Microb Biotechnol] 2026 May; Vol. 19 (5), pp. e70369.

Publication Type: Journal Article

Journal Info: Publisher: Wiley-Blackwell Country of Publication: United States NLM ID: 101316335 Publication Model: Print Cited Medium: Internet ISSN: 1751-7915 (Electronic) Linking ISSN: 17517915 NLM ISO Abbreviation: Microb Biotechnol Subsets: MEDLINE

Engineering tandem VHHs to target different epitopes to enhance antibody-dependent cell-mediated cytotoxicity.

Authors: Xu Y Jiang H Chen L et al.

Source: FEBS open bio [FEBS Open Bio] 2026 May; Vol. 16 (5), pp. 1030-1043. Date of Electronic Publication: 2025 Nov 20.

Publication Type: Journal Article

Journal Info: Publisher: John Wiley & Sons Ltd Country of Publication: England NLM ID: 101580716 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2211-5463 (Electronic) Linking ISSN: 22115463 NLM ISO Abbreviation: FEBS Open Bio Subsets: MEDLINE

Molecular engineering of lysosome-based degraders unveils a rapidly expanding therapeutic strategy.

Authors: Rivault A Dussart-Gautheret J Benhida R et al.

Source: Autophagy [Autophagy] 2026 May; Vol. 22 (5), pp. 881-903. Date of Electronic Publication: 2026 Feb 08.

Publication Type: Journal Article; Review

Journal Info: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101265188 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1554-8635 (Electronic) Linking ISSN: 15548627 NLM ISO Abbreviation: Autophagy Subsets: MEDLINE

In silico engineering of Trichoderma harzianum acetylesterase for enhanced thermal stability and efficiency.

Authors: Abolhasanzadeh Parizi A Lagzian M

Source: Journal of biomolecular structure & dynamics [J Biomol Struct Dyn] 2026 May; Vol. 44 (8), pp. 3897-3921. Date of Electronic Publication: 2025 Sep 09.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Taylor & Francis Country of Publication: England NLM ID: 8404176 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-0254 (Electronic) Linking ISSN: 07391102 NLM ISO Abbreviation: J Biomol Struct Dyn Subsets: MEDLINE

Evolution-based protein engineering: functional switching between transthyretins and 5-hydroxyisourate hydrolases.

Authors: Lemos RP Rodrigues JT Portwood G et al.

Source: Journal of biomolecular structure & dynamics [J Biomol Struct Dyn] 2026 Apr; Vol. 44 (6), pp. 3020-3036. Date of Electronic Publication: 2024 Dec 20.

Publication Type: Journal Article

Journal Info: Publisher: Taylor & Francis Country of Publication: England NLM ID: 8404176 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-0254 (Electronic) Linking ISSN: 07391102 NLM ISO Abbreviation: J Biomol Struct Dyn Subsets: MEDLINE

Using experimental results of protein design to guide biomolecular energy-function development.

Authors: Haddox HK Rocklin GJ Motta FC et al.

Source: PLoS computational biology [PLoS Comput Biol] 2026 Apr 22; Vol. 22 (4), pp. e1014215. Date of Electronic Publication: 2026 Apr 22 (Print Publication: 2026).

Publication Type: Journal Article

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238922 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7358 (Electronic) Linking ISSN: 1553734X NLM ISO Abbreviation: PLoS Comput Biol Subsets: MEDLINE

Engineering of genetically encoded programmable calcium channel inhibitory binders.

Authors: Liu X Ali S Lan TH et al.

Source: Nature communications [Nat Commun] 2026 Apr 13; Vol. 17 (1). Date of Electronic Publication: 2026 Apr 13.

Publication Type: Journal Article

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE