Search Results - "Pustilnik LR"

Design, synthesis and biological evaluations of novel VEGFR-2 inhibitors based on Fruquintinib and Cabozantinib.

Authors: Ding X Wei H Ye M et al.

Source: Molecular diversity [Mol Divers] 2026 Jun 30. Date of Electronic Publication: 2026 Jun 30.

Publication Type: Journal Article

Journal Info: Publisher: ESCOM Science Publishers Country of Publication: Netherlands NLM ID: 9516534 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-501X (Electronic) Linking ISSN: 13811991 NLM ISO Abbreviation: Mol Divers Subsets: MEDLINE

Recent Advances in Radical Coupling Reactions Directly Involving Bicyclo[1.1.1]pentane (BCP).

Authors: Jin J Yang H Xiang H et al.

Source: Topics in current chemistry (Cham) [Top Curr Chem (Cham)] 2025 Jan 18; Vol. 383 (1), pp. 6. Date of Electronic Publication: 2025 Jan 18.

Publication Type: Journal Article; Review

Journal Info: Publisher: Springer Country of Publication: Switzerland NLM ID: 101691301 Publication Model: Electronic Cited Medium: Internet ISSN: 2364-8961 (Electronic) Linking ISSN: 23648961 NLM ISO Abbreviation: Top Curr Chem (Cham) Subsets: MEDLINE

Photoinduced generation of alkyl and phthalimide nitrogen radicals from N-hydroxyphthalimide esters for the synthesis of benzophenone-type bioisosteres.

Authors: Li, Fei Dong, Jianyang Liao, Huijuan et al.

Source: SCIENCE CHINA Chemistry. Oct2024, Vol. 67 Issue 10, p3389-3396. 8p.

ABCB1 and ABCC10 polymorphisms predict sensitivity to first- and third-generation EGFR-TKIs in EGFR-mutant NSCLC.

Authors: Toda-Shiraga S Uemura T Kakihara A et al.

Source: Investigational new drugs [Invest New Drugs] 2025 Dec; Vol. 43 (6), pp. 1222-1234. Date of Electronic Publication: 2025 Dec 04.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Springer Country of Publication: United States NLM ID: 8309330 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-0646 (Electronic) Linking ISSN: 01676997 NLM ISO Abbreviation: Invest New Drugs Subsets: MEDLINE

Applications of Bridgehead Heterocycles in Drug Design and Medicinal Chemistry.

Authors: Di Martino S Amico P De Rosa M

Source: Topics in current chemistry (Cham) [Top Curr Chem (Cham)] 2025 Mar 21; Vol. 383 (2), pp. 16. Date of Electronic Publication: 2025 Mar 21.

Publication Type: Journal Article; Review

Journal Info: Publisher: Springer Country of Publication: Switzerland NLM ID: 101691301 Publication Model: Electronic Cited Medium: Internet ISSN: 2364-8961 (Electronic) Linking ISSN: 23648961 NLM ISO Abbreviation: Top Curr Chem (Cham) Subsets: MEDLINE

Delay of tympanic membrane wound healing in rats with topical application of a tyrosine kinase inhibitor.

Authors: Kaftan, Holger Reuther, Lars Miehe, Bärbel et al.

Source: Wound Repair & Regeneration. May/Jun2008, Vol. 16 Issue 3, p364-369. 6p. 6 Black and White Photographs, 1 Chart, 1 Graph.

A practical access to fluoroalkylthio(seleno)-functionalized bicyclo[1.1.1]pentanes.

Authors: Wu, Zhen Xu, Yaohui Liu, Jige et al.

Source: SCIENCE CHINA Chemistry. Aug2020, Vol. 63 Issue 8, p1025-1029. 5p.

Advances in Studies on Enzyme Inhibitors As Drugs

Authors: Gupta, Satya P.

Resource Type: eBook.

Subjects: Enzyme inhibitors

Categories: MEDICAL / Pharmacology

Isolation and identification of three new chromones from the leaves of Pimenta dioica with cytotoxic, oestrogenic and anti-oestrogenic effects.

Authors: Doyle, Brian J. Lawal, Temitope O. Locklear, Tracie D. et al.

Source: Pharmaceutical Biology. Dec2018, Vol. 56 Issue 1, p235-244. 10p.

Antitumor activity of kinetochore-associated protein 2 siRNA against lung cancer patient-derived tumor xenografts.

Authors: Makita, Yukimasa Teratani, Mika Murata, Shumpei et al.

Source: Oncology Letters. Apr2018, Vol. 15 Issue 4, p4676-4682. 7p.

An efficient synthesis of structurally diverse 2-methyl- N-[(3-phenylamino)oxetan-3-yl]-2-propanesulfinamide derivatives under catalyst free conditions.

Authors: Ugale, Sandip Gholap, Somnath

Source: Chemical Papers. Dec2017, Vol. 71 Issue 12, p2435-2443. 9p.

Computational analyses of curcuminoid analogs against kinase domain of HER2.

Authors: Yim-im, Wannarat Sawatdichaikul, Orathai Semsri, Suwanna et al.

Source: BMC Bioinformatics. 2014, Vol. 15 Issue 1, p1-13. 13p.

Design and Evaluation of Novel Antimicrobial and Anticancer Agents Among Tetrazolo[1,5-c]quinazoline-5-thione S-Derivatives.

Authors: Lyudmyla M. ANTYPENKO KOVALENKO, Sergey I. ANTYPENKO, Olexii M. et al.

Source: Scientia Pharmaceutica. Jan-Mar2013, Vol. 81 Issue 1, p15-42. 28p.

PKI 166 induced redox signalling and apoptosis through activation of p53, MAP Kinase and caspase pathway in epidermoid carcinoma.

Authors: Das, Subhasis Dey, Kaushik Kumar Bharti, Rashmi et al.

Source: Journal of Experimental Therapeutics & Oncology. 2012, Vol. 10 Issue 2, p139-153. 15p. 1 Black and White Photograph, 2 Diagrams, 5 Graphs.

Synthesis of New 6-{[ω-(Dialkylamino(heterocyclyl)alkyl]thio}-3-R-2H-[1,2,4]triazino[2,3-c]quinazoline-2-ones and Evaluation of their Anticancer and Antimicrobial Activities.

Authors: Berest, Galina G. Voskoboynik, Olexiy Y. Kovalenko, Sergiy I. et al.

Source: Scientia Pharmaceutica. Mar2012, Vol. 80 Issue 1, p37-65. 29p.

Subsequent chemotherapy reverses acquired tyrosine kinase inhibitor resistance and restores response to tyrosine kinase inhibitor in advanced non-small-cell lung cancer.

Authors: Renhua Guo Xiaofen Chen Tongshan Wang et al.

Source: BMC Cancer. 2011, Vol. 11 Issue 1, p90-94. 5p.

Inhibition of tyrosine phosphatases induces apoptosis independent from the CD95 system.

Authors: Hehner, Steffen P Hofmann, Thomas G Dröge, Wulf et al.

Source: Cell Death & Differentiation. Sep99, Vol. 6 Issue 9, p833. 9p.

Structure-activity relationships of novel quinazoline derivatives with high selectivity for HER2 over EGFR.

Authors: Lee JW Choi C Kim J et al.

Source: Archives of pharmacal research [Arch Pharm Res] 2022 Mar; Vol. 45 (3), pp. 123-141. Date of Electronic Publication: 2022 Mar 21.

Publication Type: Journal Article

Journal Info: Publisher: Pharmaceutical Society of Korea Country of Publication: Korea (South) NLM ID: 8000036 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1976-3786 (Electronic) Linking ISSN: 02536269 NLM ISO Abbreviation: Arch Pharm Res Subsets: MEDLINE

Bioactive Natural Products: Opportunities And Challenges In Medicinal Chemistry

Authors: Goutam Brahmachari

Resource Type: eBook.

Subjects: Drugs, Chemotherapy, Plant bioactive compounds, Pharmaceutical chemistry

Categories: SCIENCE / Nanoscience, SCIENCE / Chemistry / Organic, SCIENCE / Life Sciences / General

A phase I study of the farnesyltransferase inhibitor Tipifarnib in combination with the epidermal growth factor tyrosine kinase inhibitor Erlotinib in patients with advanced solid tumors.

Authors: Jazieh K Molina J Allred J et al.

Source: Investigational new drugs [Invest New Drugs] 2019 Apr; Vol. 37 (2), pp. 307-314. Date of Electronic Publication: 2018 Aug 31.

Publication Type: Clinical Trial, Phase I; Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural

Journal Info: Publisher: Springer Country of Publication: United States NLM ID: 8309330 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-0646 (Electronic) Linking ISSN: 01676997 NLM ISO Abbreviation: Invest New Drugs Subsets: MEDLINE