Search Results - "Py BF"

Pharmacological targeting of the NLRP3 LRR domain with isothiazolinones overcomes CRID3-resistant inflammation.

Authors: Woo H Jang Y Kim S et al.

Source: EMBO molecular medicine [EMBO Mol Med] 2026 Jun; Vol. 18 (6), pp. 2124-2151. Date of Electronic Publication: 2026 Apr 17.

Publication Type: Journal Article

Journal Info: Publisher: EMBO Press Country of Publication: Germany NLM ID: 101487380 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1757-4684 (Electronic) Linking ISSN: 17574676 NLM ISO Abbreviation: EMBO Mol Med Subsets: MEDLINE

IRF2 deficiency disrupts pyroptosis, NK cell interferon-γ production and resistance to Francisella.

Authors: Cornut M Djebali S Rondeau E et al.

Source: EMBO reports [EMBO Rep] 2026 Mar; Vol. 27 (5), pp. 1325-1352. Date of Electronic Publication: 2026 Jan 28.

Publication Type: Journal Article

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 100963049 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1469-3178 (Electronic) Linking ISSN: 1469221X NLM ISO Abbreviation: EMBO Rep Subsets: MEDLINE

Statins promote muscle metabolic danger and NLRP3-mediated myopathy via lower protein-prenylation and YAP.

Authors: Robin N Barra NG Foley KP et al.

Source: Science advances [Sci Adv] 2026 Jun 19; Vol. 12 (25), pp. eadz3612. Date of Electronic Publication: 2026 Jun 19.

Publication Type: Journal Article

Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101653440 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2375-2548 (Electronic) Linking ISSN: 23752548 NLM ISO Abbreviation: Sci Adv Subsets: MEDLINE

CRY-NLRP3 complexes define a circadian checkpoint controlling inflammasome activation.

Authors: Bardoulet L Burlet D Leloup H et al.

Source: BioRxiv : the preprint server for biology [bioRxiv] 2026 Feb 28. Date of Electronic Publication: 2026 Feb 28.

Publication Type: Journal Article; Preprint

Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

PD-L1⁺ plasma cells suppress T lymphocyte responses in patients with sepsis and mouse sepsis models.

Authors: Gossez M Vigneron C Vandermoeten A et al.

Corporate Authors: Gossez M Vigneron C Vandermoeten A et al.

Source: Nature communications [Nat Commun] 2025 Mar 28; Vol. 16 (1), pp. 3030. Date of Electronic Publication: 2025 Mar 28.

Publication Type: Journal Article

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

Discovery of potent and selective inhibitors of human NLRP3 with a novel mechanism of action.

Authors: Wilhelmsen K Deshpande A Tronnes S et al.

Source: The Journal of experimental medicine [J Exp Med] 2025 Nov 03; Vol. 222 (11). Date of Electronic Publication: 2025 Sep 02.

Publication Type: Journal Article

Journal Info: Publisher: Rockefeller University Press Country of Publication: United States NLM ID: 2985109R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1540-9538 (Electronic) Linking ISSN: 00221007 NLM ISO Abbreviation: J Exp Med Subsets: MEDLINE

[Functional diversity of NLRP3 gain-of-function mutations and impact on the diagnosis of CAPS hereditary auto-inflammation disease].

Transliterated Title: CAPS ou pas CAPS ? - La diversité fonctionnelle des mutations gain-de-fonction de NLRP3 modifie l’approche diagnostique des auto-inflammations héréditaires CAPS.

Authors: Cosson C Riou R Py BF

Source: Medecine sciences : M/S [Med Sci (Paris)] 2024 Oct; Vol. 40 (10), pp. 707-710. Date of Electronic Publication: 2024 Oct 25.

Publication Type: Journal Article

Journal Info: Publisher: EDK Country of Publication: France NLM ID: 8710980 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1958-5381 (Electronic) Linking ISSN: 07670974 NLM ISO Abbreviation: Med Sci (Paris) Subsets: MEDLINE; In Process

A potent NLRP3 inhibitor effective against both MCC950-sensitive and -resistant inflammation.

Authors: Kim W Kim S Woo H et al.

Source: Cell chemical biology [Cell Chem Biol] 2025 Sep 18; Vol. 32 (9), pp. 1125-1139.e7. Date of Electronic Publication: 2025 Sep 09.

Publication Type: Journal Article

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101676030 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2451-9448 (Electronic) Linking ISSN: 24519448 NLM ISO Abbreviation: Cell Chem Biol Subsets: MEDLINE

Optogenetically controlled inflammasome activation demonstrates two phases of cell swelling during pyroptosis.

Authors: Nadjar J Monnier S Bastien E et al.

Source: Science signaling [Sci Signal] 2024 Apr 23; Vol. 17 (833), pp. eabn8003. Date of Electronic Publication: 2024 Apr 23.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101465400 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1937-9145 (Electronic) Linking ISSN: 19450877 NLM ISO Abbreviation: Sci Signal Subsets: MEDLINE

Persistent NLRP3 inflammasome activation is associated with delayed immunosuppression in septic patients.

Authors: Coudereau R Bodinier M Lukaszewicz AC et al.

Source: Journal of leukocyte biology [J Leukoc Biol] 2024 Mar 29; Vol. 115 (4), pp. 706-713.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 8405628 Publication Model: Print Cited Medium: Internet ISSN: 1938-3673 (Electronic) Linking ISSN: 07415400 NLM ISO Abbreviation: J Leukoc Biol Subsets: MEDLINE

Functional analysis of NLRP3 variants provides insight into inflammasome regulation.

Authors: Py BF; Centre International de Recherche en Infectiologie (CIRI), Univ Lyon, Inserm U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, Lyon, France. benedicte.py@inserm.fr.

Source: Nature immunology [Nat Immunol] 2025 Mar; Vol. 26 (3), pp. 337-339.

Publication Type: Journal Article

Journal Info: Publisher: Nature America Inc Country of Publication: United States NLM ID: 100941354 Publication Model: Print Cited Medium: Internet ISSN: 1529-2916 (Electronic) Linking ISSN: 15292908 NLM ISO Abbreviation: Nat Immunol Subsets: MEDLINE; In Process

The double sides of NLRP3 inflammasome activation in sepsis.

Authors: Vigneron C Py BF Monneret G et al.

Source: Clinical science (London, England : 1979) [Clin Sci (Lond)] 2023 Mar 15; Vol. 137 (5), pp. 333-351.

Publication Type: Review; Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Portland Press on behalf of the Medical Research Society and the Biochemical Society Country of Publication: England NLM ID: 7905731 Publication Model: Print Cited Medium: Internet ISSN: 1470-8736 (Electronic) Linking ISSN: 01435221 NLM ISO Abbreviation: Clin Sci (Lond) Subsets: MEDLINE

Inflammasome-independent NLRP3 function enforces ATM activity in response to genotoxic stress.

Authors: Bodnar-Wachtel M Huber AL Gorry J et al.

Source: Life science alliance [Life Sci Alliance] 2023 Feb 06; Vol. 6 (4). Date of Electronic Publication: 2023 Feb 06 (Print Publication: 2023).

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Life Science Alliance, LLC Country of Publication: United States NLM ID: 101728869 Publication Model: Electronic-Print Cited Medium: Internet ISSN: 2575-1077 (Electronic) Linking ISSN: 25751077 NLM ISO Abbreviation: Life Sci Alliance Subsets: MEDLINE

[Role of inflammasome NLRP3 in the pathophysiology of viral infections: A focus on SARS-CoV-2 infection].

Transliterated Title: L’inflammasome NLRP3 dans la physiopathologie des infections virales - Un focus sur la COVID-19.

Authors: Chemarin M Dufies O Mazet A et al.

Source: Medecine sciences : M/S [Med Sci (Paris)] 2022 Jun-Jul; Vol. 38 (6-7), pp. 545-552. Date of Electronic Publication: 2022 Jun 29.

Publication Type: Journal Article; Review

Journal Info: Publisher: EDK Country of Publication: France NLM ID: 8710980 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1958-5381 (Electronic) Linking ISSN: 07670974 NLM ISO Abbreviation: Med Sci (Paris) Subsets: MEDLINE

Implication of the LRR Domain in the Regulation and Activation of the NLRP3 Inflammasome.

Authors: Cescato M Zhu YYJ Le Corre L et al.

Source: Cells [Cells] 2024 Aug 16; Vol. 13 (16). Date of Electronic Publication: 2024 Aug 16.

Publication Type: Journal Article; Review

Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409 (Electronic) Linking ISSN: 20734409 NLM ISO Abbreviation: Cells Subsets: MEDLINE

NLRP3 phosphorylation in its LRR domain critically regulates inflammasome assembly.

Authors: Niu T De Rosny C Chautard S et al.

Source: Nature communications [Nat Commun] 2021 Oct 06; Vol. 12 (1), pp. 5862. Date of Electronic Publication: 2021 Oct 06.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

Functional diversity of NLRP3 gain-of-function mutants associated with CAPS autoinflammation.

Authors: Cosson C Riou R Patoli D et al.

Source: The Journal of experimental medicine [J Exp Med] 2024 May 06; Vol. 221 (5). Date of Electronic Publication: 2024 Mar 26.

Publication Type: Journal Article

Journal Info: Publisher: Rockefeller University Press Country of Publication: United States NLM ID: 2985109R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1540-9538 (Electronic) Linking ISSN: 00221007 NLM ISO Abbreviation: J Exp Med Subsets: MEDLINE

Altered Ex Vivo NLRP3 Inflammasome Activation Is Associated with 28-Day Mortality in Septic Patients.

Authors: Coudereau R Monneret G Lukaszewicz AC et al.

Source: Viruses [Viruses] 2023 Dec 13; Vol. 15 (12). Date of Electronic Publication: 2023 Dec 13.

Publication Type: Journal Article

Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101509722 Publication Model: Electronic Cited Medium: Internet ISSN: 1999-4915 (Electronic) Linking ISSN: 19994915 NLM ISO Abbreviation: Viruses Subsets: MEDLINE

Pathogenic variants in the NLRP3 LRR domain at position 861 are responsible for a boost-dependent atypical CAPS phenotype.

Authors: Fayand A Cescato M Le Corre L et al.

Source: The Journal of allergy and clinical immunology [J Allergy Clin Immunol] 2023 Nov; Vol. 152 (5), pp. 1303-1311.e1. Date of Electronic Publication: 2023 Jul 26.

Publication Type: Journal Article

Journal Info: Publisher: Mosby Country of Publication: United States NLM ID: 1275002 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-6825 (Electronic) Linking ISSN: 00916749 NLM ISO Abbreviation: J Allergy Clin Immunol Subsets: MEDLINE

Monitoring NLRP3 Inflammasome Activation and Exhaustion in Clinical Samples: A Refined Flow Cytometry Protocol for ASC Speck Formation Measurement Directly in Whole Blood after Ex Vivo Stimulation.

Authors: Coudereau R Gossez M Py BF et al.

Source: Cells [Cells] 2022 Oct 20; Vol. 11 (20). Date of Electronic Publication: 2022 Oct 20.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409 (Electronic) Linking ISSN: 20734409 NLM ISO Abbreviation: Cells Subsets: MEDLINE