Search Results - "Pybus B"

A Review of Omadacycline for Potential Utility in the Military Health System for the Treatment of Wound Infections.

Authors: Zurawski DV Serio AW Black C et al.

Source: Military medicine [Mil Med] 2024 May 18; Vol. 189 (5-6), pp. e1353-e1361.

Publication Type: Journal Article; Review; Research Support, U.S. Gov't, Non-P.H.S.

Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 2984771R Publication Model: Print Cited Medium: Internet ISSN: 1930-613X (Electronic) Linking ISSN: 00264075 NLM ISO Abbreviation: Mil Med Subsets: MEDLINE

Liver-targeted polymeric prodrugs delivered subcutaneously improve tafenoquine therapeutic window for malaria radical cure.

Authors: Pottenger AE Roy D Srinivasan S et al.

Source: Science advances [Sci Adv] 2024 Apr 19; Vol. 10 (16), pp. eadk4492. Date of Electronic Publication: 2024 Apr 19.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101653440 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2375-2548 (Electronic) Linking ISSN: 23752548 NLM ISO Abbreviation: Sci Adv Subsets: MEDLINE

Measurements of 5,6-Orthoquinone, a Surrogate for the Presumed Active Primaquine Metabolite 5-Hydroxyprimaquine, in the Urine of Cambodian Adults.

Authors: Vanachayangkul P Sea D Wojnarski M et al.

Source: Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2022 Mar 15; Vol. 66 (3), pp. e0182121. Date of Electronic Publication: 2022 Jan 03.

Publication Type: Journal Article

Journal Info: Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 0315061 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1098-6596 (Electronic) Linking ISSN: 00664804 NLM ISO Abbreviation: Antimicrob Agents Chemother Subsets: MEDLINE

Liver-targeted polymeric prodrugs of 8-aminoquinolines for malaria radical cure.

Authors: Srinivasan S Roy D Chavas TEJ et al.

Source: Journal of controlled release : official journal of the Controlled Release Society [J Control Release] 2021 Mar 10; Vol. 331, pp. 213-227. Date of Electronic Publication: 2020 Dec 27.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Elsevier Science Publishers Country of Publication: Netherlands NLM ID: 8607908 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4995 (Electronic) Linking ISSN: 01683659 NLM ISO Abbreviation: J Control Release Subsets: MEDLINE

Combination of Subtherapeutic Doses of Tretazicar and Liposomal Amphotericin B Suppresses and Cures Leishmania major-Induced Cutaneous Lesions in Murine Models.

Authors: Caridha D Sciotti RJ Sousa J et al.

Source: ACS infectious diseases [ACS Infect Dis] 2021 Feb 12; Vol. 7 (2), pp. 506-517. Date of Electronic Publication: 2021 Feb 02.

Publication Type: Journal Article

Journal Info: Publisher: ACS Publications Country of Publication: United States NLM ID: 101654580 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2373-8227 (Electronic) Linking ISSN: 23738227 NLM ISO Abbreviation: ACS Infect Dis Subsets: MEDLINE

Discovery and Characterization of Clinical Candidate LXE408 as a Kinetoplastid-Selective Proteasome Inhibitor for the Treatment of Leishmaniases.

Authors: Nagle A Biggart A Be C et al.

Source: Journal of medicinal chemistry [J Med Chem] 2020 Oct 08; Vol. 63 (19), pp. 10773-10781. Date of Electronic Publication: 2020 Jul 29.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

Causal prophylactic efficacy of primaquine, tafenoquine, and atovaquone-proguanil against Plasmodium cynomolgi in a rhesus monkey model.

Authors: DiTusa C Kozar MP Pybus B et al.

Source: The Journal of parasitology [J Parasitol] 2014 Oct; Vol. 100 (5), pp. 671-3. Date of Electronic Publication: 2014 Apr 29.

Publication Type: Journal Article

Journal Info: Publisher: American Society of Parasitologists [etc.] Country of Publication: United States NLM ID: 7803124 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1937-2345 (Electronic) Linking ISSN: 00223395 NLM ISO Abbreviation: J Parasitol Subsets: MEDLINE

Assessment of the prophylactic activity and pharmacokinetic profile of oral tafenoquine compared to primaquine for inhibition of liver stage malaria infections.

Authors: Li Q O'Neil M Xie L et al.

Source: Malaria journal [Malar J] 2014 Apr 14; Vol. 13, pp. 141. Date of Electronic Publication: 2014 Apr 14.

Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.

Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101139802 Publication Model: Electronic Cited Medium: Internet ISSN: 1475-2875 (Electronic) Linking ISSN: 14752875 NLM ISO Abbreviation: Malar J Subsets: MEDLINE

Review: Improving the therapeutic index of 8-aminoquinolines by the use of drug combinations: review of the literature and proposal for future investigations.

Authors: Myint HY Berman J Walker L et al.

Source: The American journal of tropical medicine and hygiene [Am J Trop Med Hyg] 2011 Dec; Vol. 85 (6), pp. 1010-4.

Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Review

Journal Info: Publisher: American Society of Tropical Medicine and Hygiene Country of Publication: United States NLM ID: 0370507 Publication Model: Print Cited Medium: Internet ISSN: 1476-1645 (Electronic) Linking ISSN: 00029637 NLM ISO Abbreviation: Am J Trop Med Hyg Subsets: MEDLINE

Lead Optimization of Second-Generation Acridones as Broad-Spectrum Antimalarials.

Authors: Kancharla P Dodean RA Li Y et al.

Source: Journal of medicinal chemistry [J Med Chem] 2020 Jun 11; Vol. 63 (11), pp. 6179-6202. Date of Electronic Publication: 2020 May 26.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

Testing electrostatic complementarity in enzyme catalysis: hydrogen bonding in the ketosteroid isomerase oxyanion hole.

Authors: Kraut DA Sigala PA Pybus B et al.

Source: PLoS biology [PLoS Biol] 2006 Apr; Vol. 4 (4), pp. e99. Date of Electronic Publication: 2006 Mar 28.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101183755 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1545-7885 (Electronic) Linking ISSN: 15449173 NLM ISO Abbreviation: PLoS Biol Subsets: MEDLINE

An LC-MS based study of the metabolic profile of primaquine, an 8-aminoquinoline antiparasitic drug, with an in vitro primary human hepatocyte culture model.

Authors: Jin X Pybus BS Marcsisin R et al.

Source: European journal of drug metabolism and pharmacokinetics [Eur J Drug Metab Pharmacokinet] 2014 Jun; Vol. 39 (2), pp. 139-46.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Springer France Country of Publication: France NLM ID: 7608491 Publication Model: Print Cited Medium: Print ISSN: 0378-7966 (Print) Linking ISSN: 03787966 NLM ISO Abbreviation: Eur J Drug Metab Pharmacokinet Subsets: MEDLINE

Quantitative dissection of hydrogen bond-mediated proton transfer in the ketosteroid isomerase active site.

Authors: Sigala PA Fafarman AT Schwans JP et al.

Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2013 Jul 09; Vol. 110 (28), pp. E2552-61. Date of Electronic Publication: 2013 Jun 24.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

Journal Info: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

Ketotifen is an antimalarial prodrug of norketotifen with blood schizonticidal and liver-stage efficacy.

Authors: Milner E Sousa J Pybus B et al.

Source: European journal of drug metabolism and pharmacokinetics [Eur J Drug Metab Pharmacokinet] 2012 Mar; Vol. 37 (1), pp. 17-22.

Publication Type: Comparative Study; Journal Article

Journal Info: Publisher: Springer France Country of Publication: France NLM ID: 7608491 Publication Model: Print Cited Medium: Print ISSN: 0378-7966 (Print) Linking ISSN: 03787966 NLM ISO Abbreviation: Eur J Drug Metab Pharmacokinet Subsets: MEDLINE

Antimalarial activities of new guanidylimidazole and guanidylimidazoline derivatives.

Authors: Zhang L Sathunuru R Caridha D et al.

Source: Journal of medicinal chemistry [J Med Chem] 2011 Oct 13; Vol. 54 (19), pp. 6634-46. Date of Electronic Publication: 2011 Sep 02.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

Characterization of in vivo metabolites of WR319691, a novel compound with activity against Plasmodium falciparum.

Authors: Milner E Sousa J Pybus B et al.

Source: European journal of drug metabolism and pharmacokinetics [Eur J Drug Metab Pharmacokinet] 2011 Sep; Vol. 36 (3), pp. 151-8. Date of Electronic Publication: 2011 Jul 13.

Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.

Journal Info: Publisher: Springer France Country of Publication: France NLM ID: 7608491 Publication Model: Print-Electronic Cited Medium: Print ISSN: 0378-7966 (Print) Linking ISSN: 03787966 NLM ISO Abbreviation: Eur J Drug Metab Pharmacokinet Subsets: MEDLINE

Testing geometrical discrimination within an enzyme active site: constrained hydrogen bonding in the ketosteroid isomerase oxyanion hole.

Authors: Sigala PA Kraut DA Caaveiro JM et al.

Source: Journal of the American Chemical Society [J Am Chem Soc] 2008 Oct 15; Vol. 130 (41), pp. 13696-708. Date of Electronic Publication: 2008 Sep 23.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 7503056 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-5126 (Electronic) Linking ISSN: 00027863 NLM ISO Abbreviation: J Am Chem Soc Subsets: MEDLINE

Biochemical characterization and crystallization of recombinant 3-phosphoglycerate kinase of Plasmodium falciparum.

Authors: Pal B Pybus B Muccio DD et al.

Source: Biochimica et biophysica acta [Biochim Biophys Acta] 2004 Jun 01; Vol. 1699 (1-2), pp. 277-80.

Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.

Journal Info: Publisher: Elsevier Pub. Co Country of Publication: Netherlands NLM ID: 0217513 Publication Model: Print Cited Medium: Print ISSN: 0006-3002 (Print) Linking ISSN: 00063002 NLM ISO Abbreviation: Biochim Biophys Acta Subsets: MEDLINE

Structure-function relationship in the antifreeze activity of synthetic alanine-lysine antifreeze polypeptides.

Authors: Wierzbicki A Knight CA Rutland TJ et al.

Source: Biomacromolecules [Biomacromolecules] 2000 Summer; Vol. 1 (2), pp. 268-74.

Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 100892849 Publication Model: Print Cited Medium: Print ISSN: 1525-7797 (Print) Linking ISSN: 15257797 NLM ISO Abbreviation: Biomacromolecules Subsets: MEDLINE