Search Results - "Pybus BS"

Potent acridone antimalarial against all three life stages of Plasmodium.

Authors: Kancharla P Dodean RA Li Y et al.

Source: Nature communications [Nat Commun] 2026 Apr 14; Vol. 17 (1). Date of Electronic Publication: 2026 Apr 14.

Publication Type: Journal Article

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

Potent Acridone Antimalarial against All Three Life Stages of Plasmodium.

Authors: Kancharla P Dodean RA Li Y et al.

Source: Research square [Res Sq] 2025 Jun 27. Date of Electronic Publication: 2025 Jun 27.

Publication Type: Journal Article; Preprint

Journal Info: Country of Publication: United States NLM ID: 101768035 Publication Model: Electronic Cited Medium: Internet ISSN: 2693-5015 (Electronic) Linking ISSN: 26935015 NLM ISO Abbreviation: Res Sq Subsets: PubMed not MEDLINE

Development of Next-Generation Antimalarial Acridones with Radical Cure Potential.

Authors: Dodean RA Li Y Zhang X et al.

Source: Journal of medicinal chemistry [J Med Chem] 2025 Apr 24; Vol. 68 (8), pp. 8817-8840. Date of Electronic Publication: 2025 Apr 03.

Publication Type: Journal Article

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

Tambjamines as Fast-Acting Multistage Antimalarials.

Authors: Kumar A Li Y Dodean RA et al.

Source: ACS infectious diseases [ACS Infect Dis] 2024 Dec 13; Vol. 10 (12), pp. 4291-4300. Date of Electronic Publication: 2024 Nov 11.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

Journal Info: Publisher: ACS Publications Country of Publication: United States NLM ID: 101654580 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2373-8227 (Electronic) Linking ISSN: 23738227 NLM ISO Abbreviation: ACS Infect Dis Subsets: MEDLINE

Mechanisms of 8-aminoquinoline induced haemolytic toxicity in a G6PDd humanized mouse model.

Authors: Flaherty S Strauch P Maktabi M et al.

Source: Journal of cellular and molecular medicine [J Cell Mol Med] 2022 Jul; Vol. 26 (13), pp. 3675-3686. Date of Electronic Publication: 2022 Jun 03.

Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.

Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101083777 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1582-4934 (Electronic) Linking ISSN: 15821838 NLM ISO Abbreviation: J Cell Mol Med Subsets: MEDLINE

Discovery and Optimization of Tambjamines as a Novel Class of Antileishmanial Agents.

Authors: Kancharla P Ortiz D Fargo CM et al.

Source: Journal of medicinal chemistry [J Med Chem] 2024 May 23; Vol. 67 (10), pp. 8323-8345. Date of Electronic Publication: 2024 May 09.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

Identification and Assessment of Plasmodium berghei Merozoites and Cell Cycle by Flow Cytometry.

Authors: Li Q Xie LH Zhang J et al.

Source: Military medicine [Mil Med] 2021 Jan 25; Vol. 186 (Suppl 1), pp. 108-115.

Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.

Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 2984771R Publication Model: Print Cited Medium: Internet ISSN: 1930-613X (Electronic) Linking ISSN: 00264075 NLM ISO Abbreviation: Mil Med Subsets: MEDLINE

Corrigendum to: Determination of Cytochrome P450 Isoenzyme 2D6 (CYP2D6) Genotypes and Pharmacogenomic Impact on Primaquine Metabolism in an Active-Duty US Military Population.

Authors: Spring MD Sousa JC Li Q et al.

Source: The Journal of infectious diseases [J Infect Dis] 2020 Mar 16; Vol. 221 (7), pp. 1204.

Publication Type: Journal Article; Published Erratum

Journal Info: Publisher: Oxford University Press Country of Publication: United States NLM ID: 0413675 Publication Model: Print Cited Medium: Internet ISSN: 1537-6613 (Electronic) Linking ISSN: 00221899 NLM ISO Abbreviation: J Infect Dis Subsets: MEDLINE; PubMed not MEDLINE

Determination of Cytochrome P450 Isoenzyme 2D6 (CYP2D6) Genotypes and Pharmacogenomic Impact on Primaquine Metabolism in an Active-Duty US Military Population.

Authors: Spring MD Sousa JC Li Q et al.

Source: The Journal of infectious diseases [J Infect Dis] 2019 Oct 22; Vol. 220 (11), pp. 1761-1770.

Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.

Journal Info: Publisher: Oxford University Press Country of Publication: United States NLM ID: 0413675 Publication Model: Print Cited Medium: Internet ISSN: 1537-6613 (Electronic) Linking ISSN: 00221899 NLM ISO Abbreviation: J Infect Dis Subsets: MEDLINE

Comparison of Anti-Xa Activity in Patients Receiving Apixaban or Rivaroxaban.

Authors: Bookstaver DA Sparks K Pybus BS et al.

Source: The Annals of pharmacotherapy [Ann Pharmacother] 2018 Mar; Vol. 52 (3), pp. 251-256. Date of Electronic Publication: 2017 Oct 19.

Publication Type: Clinical Trial; Journal Article

Journal Info: Publisher: Sage Country of Publication: United States NLM ID: 9203131 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1542-6270 (Electronic) Linking ISSN: 10600280 NLM ISO Abbreviation: Ann Pharmacother Subsets: MEDLINE

Discovery of Imidazole-Based Inhibitors of Plasmodium falciparum cGMP-Dependent Protein Kinase.

Authors: Bheemanaboina RRY de Souza ML Gonzalez ML et al.

Source: ACS medicinal chemistry letters [ACS Med Chem Lett] 2021 Nov 15; Vol. 12 (12), pp. 1962-1967. Date of Electronic Publication: 2021 Nov 15 (Print Publication: 2021).

Publication Type: Journal Article

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101521073 Publication Model: eCollection Cited Medium: Print ISSN: 1948-5875 (Print) Linking ISSN: 19485875 NLM ISO Abbreviation: ACS Med Chem Lett Subsets: PubMed not MEDLINE

Pre-clinical evaluation of CYP 2D6 dependent drug-drug interactions between primaquine and SSRI/SNRI antidepressants.

Authors: Jin X Potter B Luong TL et al.

Source: Malaria journal [Malar J] 2016 May 17; Vol. 15 (1), pp. 280. Date of Electronic Publication: 2016 May 17.

Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.

Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101139802 Publication Model: Electronic Cited Medium: Internet ISSN: 1475-2875 (Electronic) Linking ISSN: 14752875 NLM ISO Abbreviation: Malar J Subsets: MEDLINE

The fibrinolytic system enables the onset of Plasmodium infection in the mosquito vector and the mammalian host.

Authors: Alves E Silva TL Radtke A Balaban A et al.

Source: Science advances [Sci Adv] 2021 Feb 05; Vol. 7 (6). Date of Electronic Publication: 2021 Feb 05 (Print Publication: 2021).

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101653440 Publication Model: Electronic-Print Cited Medium: Internet ISSN: 2375-2548 (Electronic) Linking ISSN: 23752548 NLM ISO Abbreviation: Sci Adv Subsets: MEDLINE; PubMed not MEDLINE

Safety, Pharmacokinetics, and Activity of High-Dose Ivermectin and Chloroquine against the Liver Stage of Plasmodium cynomolgi Infection in Rhesus Macaques.

Authors: Vanachayangkul P Im-Erbsin R Tungtaeng A et al.

Source: Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2020 Aug 20; Vol. 64 (9). Date of Electronic Publication: 2020 Aug 20 (Print Publication: 2020).

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 0315061 Publication Model: Electronic-Print Cited Medium: Internet ISSN: 1098-6596 (Electronic) Linking ISSN: 00664804 NLM ISO Abbreviation: Antimicrob Agents Chemother Subsets: MEDLINE

Enantioselective metabolism of primaquine by human CYP2D6.

Authors: Fasinu PS Tekwani BL Nanayakkara NP et al.

Source: Malaria journal [Malar J] 2014 Dec 17; Vol. 13, pp. 507. Date of Electronic Publication: 2014 Dec 17.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101139802 Publication Model: Electronic Cited Medium: Internet ISSN: 1475-2875 (Electronic) Linking ISSN: 14752875 NLM ISO Abbreviation: Malar J Subsets: MEDLINE

Tafenoquine and NPC-1161B require CYP 2D metabolism for anti-malarial activity: implications for the 8-aminoquinoline class of anti-malarial compounds.

Authors: Marcsisin SR Sousa JC Reichard GA et al.

Source: Malaria journal [Malar J] 2014 Jan 03; Vol. 13, pp. 2. Date of Electronic Publication: 2014 Jan 03.

Publication Type: Journal Article

Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101139802 Publication Model: Electronic Cited Medium: Internet ISSN: 1475-2875 (Electronic) Linking ISSN: 14752875 NLM ISO Abbreviation: Malar J Subsets: MEDLINE

CYP450 phenotyping and metabolite identification of quinine by accurate mass UPLC-MS analysis: a possible metabolic link to blackwater fever.

Authors: Marcsisin SR Jin X Bettger T et al.

Source: Malaria journal [Malar J] 2013 Jun 21; Vol. 12, pp. 214. Date of Electronic Publication: 2013 Jun 21.

Publication Type: Journal Article

Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101139802 Publication Model: Electronic Cited Medium: Internet ISSN: 1475-2875 (Electronic) Linking ISSN: 14752875 NLM ISO Abbreviation: Malar J Subsets: MEDLINE

The metabolism of primaquine to its active metabolite is dependent on CYP 2D6.

Authors: Pybus BS Marcsisin SR Jin X et al.

Source: Malaria journal [Malar J] 2013 Jun 20; Vol. 12, pp. 212. Date of Electronic Publication: 2013 Jun 20.

Publication Type: Journal Article

Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101139802 Publication Model: Electronic Cited Medium: Internet ISSN: 1475-2875 (Electronic) Linking ISSN: 14752875 NLM ISO Abbreviation: Malar J Subsets: MEDLINE

CYP450 phenotyping and accurate mass identification of metabolites of the 8-aminoquinoline, anti-malarial drug primaquine.

Authors: Pybus BS Sousa JC Jin X et al.

Source: Malaria journal [Malar J] 2012 Aug 02; Vol. 11, pp. 259. Date of Electronic Publication: 2012 Aug 02.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101139802 Publication Model: Electronic Cited Medium: Internet ISSN: 1475-2875 (Electronic) Linking ISSN: 14752875 NLM ISO Abbreviation: Malar J Subsets: MEDLINE

Primaquine pharmacology in the context of CYP 2D6 pharmacogenomics: Current state of the art.

Authors: Marcsisin SR Reichard G Pybus BS

Source: Pharmacology & therapeutics [Pharmacol Ther] 2016 May; Vol. 161, pp. 1-10. Date of Electronic Publication: 2016 Mar 22.

Publication Type: Journal Article; Review; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Pergamon Press Country of Publication: England NLM ID: 7905840 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-016X (Electronic) Linking ISSN: 01637258 NLM ISO Abbreviation: Pharmacol Ther Subsets: MEDLINE