Search Results - "Pyles EA"

Evaluating Drug-Target Complexes in Therapeutic Monoclonal Antibodies Using A4F-MALS: Implications for Drug Development and Clinical Design.

Authors: Liu N Kotowski D Ong ET et al.

Source: Journal of immunology research [J Immunol Res] 2026; Vol. 2026 (1), pp. e8063033.

Publication Type: Journal Article

Journal Info: Publisher: Wiley Country of Publication: Egypt NLM ID: 101627166 Publication Model: Print Cited Medium: Internet ISSN: 2314-7156 (Electronic) Linking ISSN: 23147156 NLM ISO Abbreviation: J Immunol Res Subsets: MEDLINE

Leveraging digestion-assisted capillary electrophoresis sodium dodecyl sulfate (CE-SDS) to monitor galactosylation in monoclonal antibodies.

Authors: Rao R Howie DA Di Grandi D et al.

Source: Journal of pharmaceutical and biomedical analysis [J Pharm Biomed Anal] 2026 Mar 15; Vol. 270, pp. 117273. Date of Electronic Publication: 2025 Nov 19.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Science Country of Publication: England NLM ID: 8309336 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-264X (Electronic) Linking ISSN: 07317085 NLM ISO Abbreviation: J Pharm Biomed Anal Subsets: MEDLINE

Comparison of enriched charge variants from different anti-CD3 bispecific antibodies reveals differential susceptibility of each bispecific arm to post-translational modification.

Authors: Nguyen JB Liu S Howie DA et al.

Source: Protein science : a publication of the Protein Society [Protein Sci] 2025 Apr; Vol. 34 (4), pp. e70079.

Publication Type: Journal Article; Comparative Study

Journal Info: Publisher: Cold Spring Harbor Laboratory Press Country of Publication: United States NLM ID: 9211750 Publication Model: Print Cited Medium: Internet ISSN: 1469-896X (Electronic) Linking ISSN: 09618368 NLM ISO Abbreviation: Protein Sci Subsets: MEDLINE

Insights into the structural differences between homo- and heterodimers enriched from a cocktail of monoclonal antibodies against SARS-CoV-2.

Authors: Nguyen JB Liu S Yan Y et al.

Source: Scientific reports [Sci Rep] 2026 Feb 03; Vol. 16 (1), pp. 7024. Date of Electronic Publication: 2026 Feb 03.

Publication Type: Journal Article

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

Enrichment strategy and initial characterization of heterodimers enriched from a co-formulated cocktail of therapeutic antibodies against SARS-COV-2.

Authors: Liu S Yan Y Secor CM et al.

Source: MAbs [MAbs] 2024 Jan-Dec; Vol. 16 (1), pp. 2338301. Date of Electronic Publication: 2024 Apr 09.

Publication Type: Journal Article

Journal Info: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101479829 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1942-0870 (Electronic) Linking ISSN: 19420862 NLM ISO Abbreviation: MAbs Subsets: MEDLINE

A target affinity enrichment workflow to characterize critical post-translational modifications within therapeutic antibodies.

Authors: Prinston JE Peng W Provoncha K et al.

Source: Journal of pharmaceutical sciences [J Pharm Sci] 2025 May; Vol. 114 (5), pp. 103710. Date of Electronic Publication: 2025 Feb 27.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 2985195R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-6017 (Electronic) Linking ISSN: 00223549 NLM ISO Abbreviation: J Pharm Sci Subsets: MEDLINE

Comparative analysis of empty and full adeno-associated viruses under stress conditions by anion-exchange chromatography, analytical ultracentrifugation, and mass photometry.

Authors: Townsend JA Li S Sweezy L et al.

Source: Journal of pharmaceutical sciences [J Pharm Sci] 2025 Feb; Vol. 114 (2), pp. 1237-1244. Date of Electronic Publication: 2025 Jan 17.

Publication Type: Journal Article; Comparative Study

Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 2985195R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-6017 (Electronic) Linking ISSN: 00223549 NLM ISO Abbreviation: J Pharm Sci Subsets: MEDLINE

Comparison of capillary electrophoresis-based methods for the analytical characterization of purity and stability of in vitro transcribed mRNA.

Authors: Mantri P Juneja B Henderson S et al.

Source: Journal of pharmaceutical and biomedical analysis [J Pharm Biomed Anal] 2024 Oct 15; Vol. 249, pp. 116352. Date of Electronic Publication: 2024 Jul 14.

Publication Type: Journal Article; Comparative Study

Journal Info: Publisher: Elsevier Science Country of Publication: England NLM ID: 8309336 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-264X (Electronic) Linking ISSN: 07317085 NLM ISO Abbreviation: J Pharm Biomed Anal Subsets: MEDLINE

Development of Biolayer Interferometry (BLI)-Based Double-Stranded RNA Detection Method with Application in mRNA-Based Therapeutics and Vaccines.

Authors: Silas DS Juneja B Kaur K et al.

Source: Pharmaceutics [Pharmaceutics] 2024 Sep 19; Vol. 16 (9). Date of Electronic Publication: 2024 Sep 19.

Publication Type: Journal Article

Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101534003 Publication Model: Electronic Cited Medium: Print ISSN: 1999-4923 (Print) Linking ISSN: 19994923 NLM ISO Abbreviation: Pharmaceutics Subsets: PubMed not MEDLINE

Development of a platform method for rapid detection and characterization of domain-specific post-translational modifications in bispecific antibodies.

Authors: Liu S Nguyen JB Zhao Y et al.

Source: Journal of pharmaceutical and biomedical analysis [J Pharm Biomed Anal] 2024 Jul 15; Vol. 244, pp. 116120. Date of Electronic Publication: 2024 Mar 18.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Science Country of Publication: England NLM ID: 8309336 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-264X (Electronic) Linking ISSN: 07317085 NLM ISO Abbreviation: J Pharm Biomed Anal Subsets: MEDLINE

Comprehensive chromatographic assessment of forced degraded in vitro transcribed mRNA.

Authors: Dayeh DM Cika J Moon Y et al.

Source: Journal of chromatography. A [J Chromatogr A] 2024 May 10; Vol. 1722, pp. 464885. Date of Electronic Publication: 2024 Apr 06.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 9318488 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3778 (Electronic) Linking ISSN: 00219673 NLM ISO Abbreviation: J Chromatogr A Subsets: MEDLINE

A single-nucleotide resolution capillary gel electrophoresis workflow for poly(A) tail characterization in the development of mRNA therapeutics and vaccines.

Authors: Di Grandi D Dayeh DM Kaur K et al.

Source: Journal of pharmaceutical and biomedical analysis [J Pharm Biomed Anal] 2023 Nov 30; Vol. 236, pp. 115692. Date of Electronic Publication: 2023 Sep 02.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Science Country of Publication: England NLM ID: 8309336 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-264X (Electronic) Linking ISSN: 07317085 NLM ISO Abbreviation: J Pharm Biomed Anal Subsets: MEDLINE

High-sensitivity and high-resolution therapeutic antibody charge variant and impurity characterization by microfluidic native capillary electrophoresis-mass spectrometry.

Authors: Wu Z Wang H Wu J et al.

Source: Journal of pharmaceutical and biomedical analysis [J Pharm Biomed Anal] 2023 Jan 20; Vol. 223, pp. 115147. Date of Electronic Publication: 2022 Nov 08.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Science Country of Publication: England NLM ID: 8309336 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-264X (Electronic) Linking ISSN: 07317085 NLM ISO Abbreviation: J Pharm Biomed Anal Subsets: MEDLINE

Human Serum Albumin Mitigates Formation of Fatty Acid Particles in Polysorbate-Containing Solutions.

Authors: Kim DM Stansberry-Perkins K Marlow MS et al.

Source: Journal of pharmaceutical sciences [J Pharm Sci] 2022 Nov; Vol. 111 (11), pp. 3185-3188. Date of Electronic Publication: 2022 Aug 14.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 2985195R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-6017 (Electronic) Linking ISSN: 00223549 NLM ISO Abbreviation: J Pharm Sci Subsets: MEDLINE

Deciphering the High Viscosity of a Therapeutic Monoclonal Antibody in High Concentration Formulations by Microdialysis-Hydrogen/Deuterium Exchange Mass Spectrometry.

Authors: Xu X Zhang A Xu Y et al.

Source: Journal of pharmaceutical sciences [J Pharm Sci] 2022 May; Vol. 111 (5), pp. 1335-1345. Date of Electronic Publication: 2022 Jan 07.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 2985195R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-6017 (Electronic) Linking ISSN: 00223549 NLM ISO Abbreviation: J Pharm Sci Subsets: MEDLINE

Binding and neutralization of vascular endothelial growth factor (VEGF) and related ligands by VEGF Trap, ranibizumab and bevacizumab.

Authors: Papadopoulos N Martin J Ruan Q et al.

Source: Angiogenesis [Angiogenesis] 2012 Jun; Vol. 15 (2), pp. 171-85.

Publication Type: Journal Article

Journal Info: Publisher: Springer Country of Publication: Germany NLM ID: 9814575 Publication Model: Print Cited Medium: Internet ISSN: 1573-7209 (Electronic) Linking ISSN: 09696970 NLM ISO Abbreviation: Angiogenesis Subsets: MEDLINE

Cytokine traps: multi-component, high-affinity blockers of cytokine action.

Authors: Economides AN Carpenter LR Rudge JS et al.

Source: Nature medicine [Nat Med] 2003 Jan; Vol. 9 (1), pp. 47-52. Date of Electronic Publication: 2002 Dec 16.

Publication Type: Journal Article

Journal Info: Publisher: Nature Publishing Company Country of Publication: United States NLM ID: 9502015 Publication Model: Print-Electronic Cited Medium: Print ISSN: 1078-8956 (Print) Linking ISSN: 10788956 NLM ISO Abbreviation: Nat Med Subsets: MEDLINE

VEGF Trap complex formation measures production rates of VEGF, providing a biomarker for predicting efficacious angiogenic blockade.

Authors: Rudge JS Holash J Hylton D et al.

Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2007 Nov 20; Vol. 104 (47), pp. 18363-70. Date of Electronic Publication: 2007 Nov 13.

Publication Type: Journal Article

Journal Info: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

Escherichia coli cAMP receptor protein-DNA complexes. 1. Energetic contributions of half-sites and flanking sequences in DNA recognition.

Authors: Pyles EA Chin AJ Lee JC

Source: Biochemistry [Biochemistry] 1998 Apr 14; Vol. 37 (15), pp. 5194-200.

Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 0370623 Publication Model: Print Cited Medium: Print ISSN: 0006-2960 (Print) Linking ISSN: 00062960 NLM ISO Abbreviation: Biochemistry Subsets: MEDLINE

Escherichia coli cAMP receptor protein-DNA complexes. 2. Structural asymmetry of DNA bending.

Authors: Pyles EA Lee JC

Source: Biochemistry [Biochemistry] 1998 Apr 14; Vol. 37 (15), pp. 5201-10.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 0370623 Publication Model: Print Cited Medium: Print ISSN: 0006-2960 (Print) Linking ISSN: 00062960 NLM ISO Abbreviation: Biochemistry Subsets: MEDLINE