Search Results - "Pyrazole derivatives"

Synthesis and molecular docking of novel pyrazole, pyrimidine, and pyridine derivatives as potent antimicrobial, antibiofilm, and anticancer agents.

Authors: Hassan, A. M. A. Essam, E. S. Hamed, Selwan et al.

Source: Scientific Reports. 8/8/2026, Vol. 16 Issue 1, p1-21. 21p.

SYNTHESIS, IN VITRO PHARMACOLOGICAL EVALUATION, AND COMPUTATIONAL ASSESSMENTS OF SOME ISATIN-TRIAZOLE-PYRAZOLE HYBRIDS AS POTENTIAL ANTI-DIABETIC AND ANTI-ALZHEIMER AGENTS.

Authors: Almehizia, Abdulrahman A. Al-Omar, Mohamed A. Naglah, Ahmed M. et al.

Source: Bulletin of the Chemical Society of Ethiopia. 2026, Vol. 40 Issue 8, p1691-1706. 16p.

Pyrazole‐Derived Antibacterial Compounds Effectively Treat Methicillin‐Resistant Staphylococcus Aureus Infections by Inhibiting Aspartate Transcarbamoylase.

Authors: Yang, Xiaorong Cao, Xinyuan Dai, Lixia et al.

Source: Advanced Science. Jul2026, p1. 25p. 10 Illustrations.

SYNTHESIS, CHARACTERIZATION, ENZYMATIC ACTIVITY OF SOME PYRAZOLINE DERIVATIVES, AZO DYES, AND CHALCONES DERIVED FROM ETHYL 4-(TRIFLUOROMETHYL)BENZOATE.

Authors: Abdullah, Sh. H. Saber, A. B. Al-Badrany, K. A. et al.

Source: Chemical Problems / Kimya Problemləri. 2026, Vol. 24 Issue 3, p346-361. 16p.

Design, synthesis, antimicrobial evaluation, and molecular docking studies of novel biphenyl-bearing pyrazole derivatives.

Authors: Kasundra, Dinkal V. Patel, Paresh N.

Source: Discover Chemistry. 6/11/2026, Vol. 3 Issue 1, p1-16. 16p.

Diversity and Multi-Target Potential of Pyrazole, Imidazole or Triazole Derivatives in Modern Anticancer Therapy.

Authors: Mysłek, Martyna Kaczmarek, Anna Świątek, Piotr et al.

Source: International Journal of Molecular Sciences. May2026, Vol. 27 Issue 10, p4172. 63p.

Design, synthesis, and insecticidal potency of novel 3-methyl-pyrazole derivatives against Culex pipiens larvae.

Authors: Nofal, Hager R. Ali, Ali Khalil Ismail, Mahmoud F. et al.

Source: Scientific Reports. 5/9/2026, Vol. 16 Issue 1, p1-21. 21p.

EXPLORING SELENIUM NANOPARTICLES SYNTHESIZED USING PYRAZOLE-BASED DERIVATIVES: SYNTHESIS AND IN VITRO BIOLOGICAL EVALUATION AS POTENTIAL ANTI-DIABETIC AND ANTI-ALZHEIMER'S AGENTS.

Authors: Almehizia, Abdulrahman A. Al-Omar, Mohamed A. Naglah, Ahmed M. et al.

Source: Bulletin of the Chemical Society of Ethiopia. 2026, Vol. 40 Issue 4, p879-892. 14p.

Derivatives of 1-(2-Pyridyl)-3-pyrazolecarboxylic Acids as Ligands for Binding f-Elements.

Authors: Abramova, Olga I. Ivanov, Alexey V. Borisova, Nataliya E. et al.

Source: Molecules. Feb2026, Vol. 31 Issue 3, p541. 12p.

Design, Docking, Synthesis, and Biological Evaluation of Pyrazolone Derivatives as Potential Dual-Action Antimicrobial and Antiepileptic Agents.

Authors: Al-ebini, Yousef Chandramouli, Manojmouli Koppuravuri, Naga Prashant et al.

Source: Pharmaceuticals (14248247). Feb2026, Vol. 19 Issue 2, p193. 22p.

Discovery of pyrazole-pyrazoline derivatives as VEGFR-2 kinase inhibitors: In silico approach.

Authors: Wanode, Deepali M. Bhendarkar, Kumud P. Khedekar, Pramod B.

Source: Journal of Applied Pharmaceutical Science. Feb2026, Vol. 16 Issue 2, p122-135. 14p.

Structure–activity modeling and hybrid machine learning-based prediction of bioactivity in pyrazole derivatives for drug discovery applications.

Authors: ŞAHİN, Kader KILIÇARSLAN, Serhat DURDAĞI, Serdar et al.

Source: Turkish Journal of Biology. 2026, Vol. 50 Issue 1, p37-61. 26p.

Multifaceted insights of experimental, surface, and computational investigations for a synthesized pyrazolyl derivative inhibitor for carbon steel corrosion in an acidic environment.

Authors: Khedr, Basma M. A. Ramadan, Sayed K. Abdelkader, Sherine A. et al.

Source: Scientific Reports. 12/4/2025, Vol. 15 Issue 1, p1-23. 23p.

Microwave-Irradiated Eco-Friendly Multicomponent Synthesis of Substituted Pyrazole Derivatives and Evaluation of Their Antibacterial Potential.

Authors: Mntambo, Bahle L. Aribisala, Jamiu O. Sabiu, Saheed et al.

Source: Chemistry (2624-8549). Dec2025, Vol. 7 Issue 6, p191. 21p.

Synthesis of novel pyrazole derivatives and neuroprotective effect investigation.

Authors: Feng, Aihua Zeng, Qing Wang, Jun et al.

Source: Journal of Enzyme Inhibition & Medicinal Chemistry. Dec2025, Vol. 40 Issue 1, p1-22. 22p.

Design, synthesis, and in-silico studies of novel pyrazole-fused chalcone amine derivatives as anti-inflammatory agents.

Authors: Das, Siddhartha Sankar Choudhury, Nilotpal Das, Chandan et al.

Source: Discover Chemistry. Dec2025, Vol. 2 Issue 1, p1-38. 38p.

Design, synthesis, crystal structure, spectral characterization of new pyrazole derivatives and their α-amylase inhibitory potential.

Authors: Govindappa, Dinesh Kumar Kumara, Karthik Mylarappa, Swati et al.

Source: Journal of Chemical Sciences. Jun2026, Vol. 138 Issue 2, p1-12. 12p.

Subjects: Pyrazole derivatives, Amylase inhibitors, Enzyme inhibitors, Spectrum analysis, Chemical synthesis, Crystal structure, Hypoglycemic agents, Catalysis

On the Question of the Application Potential and the Molecular Mechanism of the Formation of 1,3-Diaryl-5-Nitropyrazoles from Trichloromethylated Diarylnitropyrazolines.

Authors: Kula, Karolina Jasiński, Radomir

Source: Molecules. Nov2025, Vol. 30 Issue 21, p4306. 20p.

Tumor-specific cytotoxicity of pyrazole-based chalcone derivatives in human oral squamous cell carcinoma cell lines.

Authors: TUĞRAK SAKARYA, Mehtap GÜL, Halise İnci Hiroshi SAKAGAMI et al.

Source: Turkish Journal of Biology. 2025, Vol. 49 Issue 6, p712-S1. 17p.

Pyrazole-Imidazoline Derivative Prevents Cardiac Damage and Mortality in Acute Trypanosoma cruzi Infection.

Authors: Orlando, Lorraine Martins Rocha Lara, Leonardo da Silva de Souza, Thamyris Pérez et al.

Source: Pharmaceuticals (14248247). Oct2025, Vol. 18 Issue 10, p1552. 20p.