Search Results - "Pyruvates"

Exogenous pyruvate restores mitochondrial bioenergetics by synergizing with the AMPK-mTOR-SIRT3 pathway to alleviate sepsis-associated acute kidney injury.

Authors: Wang Y Wang W Sun J et al.

Source: Chemico-biological interactions [Chem Biol Interact] 2026 Jul 01; Vol. 434, pp. 112089. Date of Electronic Publication: 2026 Apr 22.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: Ireland NLM ID: 0227276 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7786 (Electronic) Linking ISSN: 00092797 NLM ISO Abbreviation: Chem Biol Interact Subsets: MEDLINE

Modulation of HMGB1-mediated neuroinflammation and synaptic plasticity by ethyl pyruvate reduces methamphetamine reward and motivation in male rats.

Authors: Liu H Wang F Zhang Z et al.

Source: Brain, behavior, and immunity [Brain Behav Immun] 2026 May; Vol. 134, pp. 106481. Date of Electronic Publication: 2026 Feb 10.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8800478 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2139 (Electronic) Linking ISSN: 08891591 NLM ISO Abbreviation: Brain Behav Immun Subsets: MEDLINE

3-Bromopyruvate Impairs Mitochondrial Function in Trypanosoma cruzi.

Authors: da Costa RO Barreto-Campos D Barbosa-de-Barros J et al.

Source: Pathogens (Basel, Switzerland) [Pathogens] 2025 Jun 25; Vol. 14 (7). Date of Electronic Publication: 2025 Jun 25.

Publication Type: Evaluation Study; Journal Article

Journal Info: Publisher: MDPI AG Country of Publication: Switzerland NLM ID: 101596317 Publication Model: Electronic Cited Medium: Internet ISSN: 2076-0817 (Electronic) Linking ISSN: 20760817 NLM ISO Abbreviation: Pathogens Subsets: MEDLINE

Ethyl Pyruvate as a Potential Therapeutic Agent for Endometriosis: A Perspective.

Authors: Yadav SS Nair RR

Source: Reproductive sciences (Thousand Oaks, Calif.) [Reprod Sci] 2025 Jun; Vol. 32 (6), pp. 1979-1986. Date of Electronic Publication: 2025 May 13.

Publication Type: Journal Article; Review

Journal Info: Publisher: Springer Country of Publication: United States NLM ID: 101291249 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1933-7205 (Electronic) Linking ISSN: 19337191 NLM ISO Abbreviation: Reprod Sci Subsets: MEDLINE

ME3BP-7 is a targeted cytotoxic agent that rapidly kills pancreatic cancer cells expressing high levels of monocarboxylate transporter MCT1.

Authors: Rincon-Torroella J Dal Molin M Mog B et al.

Source: ELife [Elife] 2025 May 20; Vol. 13. Date of Electronic Publication: 2025 May 20.

Publication Type: Journal Article

Journal Info: Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic Cited Medium: Internet ISSN: 2050-084X (Electronic) Linking ISSN: 2050084X NLM ISO Abbreviation: Elife Subsets: MEDLINE

Ethyl Pyruvate Promotes Wound Healing in Elastase-Induced Lung Injury in Mice as Assessed by Hyperpolarized ¹²⁹Xe Magnetic Resonance Imaging.

Authors: Kimura A Shimokawa A Stewart NJ et al.

Source: Molecular imaging and biology [Mol Imaging Biol] 2026 Feb; Vol. 28 (1), pp. 169-180. Date of Electronic Publication: 2025 Dec 10.

Publication Type: Journal Article

Journal Info: Publisher: Springer Country of Publication: United States NLM ID: 101125610 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1860-2002 (Electronic) Linking ISSN: 15361632 NLM ISO Abbreviation: Mol Imaging Biol Subsets: MEDLINE

Hexokinase 2 upregulation is associated with glycolytic reprogramming and neuroinflammation in hypoxic-ischemic brain damage: a therapeutic target for early intervention.

Authors: Li Y Qin C Miao C et al.

Source: Frontiers in immunology [Front Immunol] 2026 Jun 12; Vol. 17, pp. 1837728. Date of Electronic Publication: 2026 Jun 12 (Print Publication: 2026).

Publication Type: Journal Article

Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE

Cooperative engineering of distal and proximal domains in L-alanine dehydrogenase breaks activity-stability trade-off for efficient hydroxypyruvic acid synthesis.

Authors: Wang C Miao J Chen Q et al.

Source: International journal of biological macromolecules [Int J Biol Macromol] 2026 Apr; Vol. 359, pp. 151855. Date of Electronic Publication: 2026 Apr 04.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7909578 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0003 (Electronic) Linking ISSN: 01418130 NLM ISO Abbreviation: Int J Biol Macromol Subsets: MEDLINE

Targeting Glycolytic Enzymes with 3-Bromopyruvic Acid to Enhance the Efficacy of Interventional Embolization in Hepatocellular Carcinoma.

Authors: Wang M Wu XN Cheng X et al.

Source: Current medical science [Curr Med Sci] 2025 Feb; Vol. 45 (1), pp. 114-121. Date of Electronic Publication: 2025 Feb 21.

Publication Type: Journal Article

Journal Info: Publisher: Huazhong University of Science and Technology Country of Publication: China NLM ID: 101729993 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2523-899X (Electronic) Linking ISSN: 2523899X NLM ISO Abbreviation: Curr Med Sci Subsets: MEDLINE

Ethyl pyruvate alleviates pulmonary arterial hypertension via PI3K-Akt signaling.

Authors: Lv X Li J Wei R et al.

Source: Molecular and cellular biochemistry [Mol Cell Biochem] 2025 Feb; Vol. 480 (2), pp. 1045-1054. Date of Electronic Publication: 2024 May 14.

Publication Type: Journal Article

Journal Info: Publisher: Springer Country of Publication: Netherlands NLM ID: 0364456 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-4919 (Electronic) Linking ISSN: 03008177 NLM ISO Abbreviation: Mol Cell Biochem Subsets: MEDLINE

Photo-Thermally Controllable Tumor Metabolic Modulation to Assist T Cell Activation for Boosting Immunotherapy.

Authors: Ma J Hua L Zhu Y et al.

Source: International journal of nanomedicine [Int J Nanomedicine] 2024 Nov 03; Vol. 19, pp. 11181-11194. Date of Electronic Publication: 2024 Nov 03 (Print Publication: 2024).

Publication Type: Journal Article

Journal Info: Publisher: DOVE Medical Press Country of Publication: New Zealand NLM ID: 101263847 Publication Model: eCollection Cited Medium: Internet ISSN: 1178-2013 (Electronic) Linking ISSN: 11769114 NLM ISO Abbreviation: Int J Nanomedicine Subsets: MEDLINE

Synergistic Cancer Metabolic Therapy via Co-Delivery of 3-Bromopyruvate and Temozolomide with a Supramolecular Shuttle.

Authors: Bellavita R Prisco M Palladino S et al.

Source: ACS applied materials & interfaces [ACS Appl Mater Interfaces] 2025 Nov 05; Vol. 17 (44), pp. 60342-60360. Date of Electronic Publication: 2025 Oct 22.

Publication Type: Journal Article

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101504991 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1944-8252 (Electronic) Linking ISSN: 19448244 NLM ISO Abbreviation: ACS Appl Mater Interfaces Subsets: MEDLINE

Ethyl pyruvate shields the brain from oxidative damage: a Keap1-Nrf2-dependent mechanism in subarachnoid hemorrhage.

Authors: Zhang M Deng X Teng Z et al.

Source: Brain research [Brain Res] 2025 Nov 01; Vol. 1866, pp. 149939. Date of Electronic Publication: 2025 Sep 09.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 0045503 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-6240 (Electronic) Linking ISSN: 00068993 NLM ISO Abbreviation: Brain Res Subsets: MEDLINE

Ethyl pyruvate alleviates NLRP3/Caspase-1/GSDMD-mediated neuronal pyroptosis in neonatal rats with hypoxic-ischemic brain damage.

Authors: Sha S Jin N Xie X et al.

Source: International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience [Int J Dev Neurosci] 2024 Oct; Vol. 84 (6), pp. 594-604. Date of Electronic Publication: 2024 Jun 28.

Publication Type: Journal Article

Journal Info: Publisher: John Wiley & Sons, Inc Country of Publication: United States NLM ID: 8401784 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-474X (Electronic) Linking ISSN: 07365748 NLM ISO Abbreviation: Int J Dev Neurosci Subsets: MEDLINE

Improving the Catalyst Efficiency for Hyperpolarization of Pyruvate Derivatives by Means of Hydrogenative PHIP.

Authors: Di Matteo G Bondar O Carrera C et al.

Source: ChemMedChem [ChemMedChem] 2025 Oct 06; Vol. 20 (19), pp. e202500379. Date of Electronic Publication: 2025 Sep 12.

Publication Type: Journal Article

Journal Info: Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 101259013 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1860-7187 (Electronic) Linking ISSN: 18607179 NLM ISO Abbreviation: ChemMedChem Subsets: MEDLINE

Exogenous Pyruvate in Defense Against Human-Exposure Toxicants: A Review of In Vitro and In Vivo Evidence.

Authors: Zwolak I; Department of Biomedicine and Environmental Research, Institute of Biological Sciences, Faculty of Medicine, The John Paul II Catholic University of Lublin, Konstantynów Ave. 1J, 20-708 Lublin, Poland.

Source: International journal of molecular sciences [Int J Mol Sci] 2025 Aug 27; Vol. 26 (17). Date of Electronic Publication: 2025 Aug 27.

Publication Type: Journal Article; Review

Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

Continuous Pyruvate Supplementation Enhances Neuroprotective Resilience Against Kainate-Induced Status Epilepticus Through Metabolic Preconditioning.

Authors: Cho, Yong Jae Lee, Soo Jin Kim, Yuna et al.

Source: Biomolecules (2218-273X). Jun2026, Vol. 16 Issue 6, p805. 29p.

Sodium Pyruvate Supplementation Enhances Infectious Yield and Supports Host-Cell Stability of Rabies Virus CVS-11 in a High-Density Macrocarrier-Based Tide-Motion Culture System.

Authors: Imanbekova, Tolganay Akhmetsadykov, Nurlan Shanbayev, Bakdaulet et al.

Source: Viruses (1999-4915). Jun2026, Vol. 18 Issue 6, p600. 16p.

Pyrimidines maintain mitochondrial pyruvate oxidation to support de novo lipogenesis.

Authors: Sahu U Villa E Reczek CR et al.

Source: Science (New York, N.Y.) [Science] 2024 Mar 29; Vol. 383 (6690), pp. 1484-1492. Date of Electronic Publication: 2024 Mar 28.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE

Hydroxy(phenyl)pyruvic acid reductase in Actaea racemosa L.: a putative enzyme in cimicifugic and fukinolic acid biosynthesis.

Authors: Jahn A Petersen M

Source: Planta [Planta] 2024 Mar 28; Vol. 259 (5), pp. 102. Date of Electronic Publication: 2024 Mar 28.

Publication Type: Journal Article

Journal Info: Publisher: Springer-Verlag [etc.] Country of Publication: Germany NLM ID: 1250576 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-2048 (Electronic) Linking ISSN: 00320935 NLM ISO Abbreviation: Planta Subsets: MEDLINE