Search Results - "Rayner SL"

Theme 03 - In Vitro Experimental Models.

Authors: Al-Shanti, N. Khan, M. Ayoubi, R. et al.

Source: Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. 2023 Suppl1, Vol. 24, p115-127. 13p.

Theme 3 In vitro experimental models.

Authors: Yang, Shu Wu, Sharlynn Fifita, Jennifer et al.

Source: Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. 2019 Supplement, Vol. 20, p135-159. 25p.

TDP-43 is coming to the cottage: A new tool to study neurodegenerative diseases.

Authors: Rayner SL Gitler AD

Source: PLoS biology [PLoS Biol] 2026 Mar 25; Vol. 24 (3), pp. e3003697. Date of Electronic Publication: 2026 Mar 25 (Print Publication: 2026).

Publication Type: Journal Article; Comment

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101183755 Publication Model: eCollection Cited Medium: Internet ISSN: 1545-7885 (Electronic) Linking ISSN: 15449173 NLM ISO Abbreviation: PLoS Biol Subsets: MEDLINE

TDP-43-mediated alternative polyadenylation is associated with a reduction in VPS35 and VPS29 expression in frontotemporal dementia.

Authors: Maheswari Jawahar, Vidhya Zeng, Yi Armour, Ellen M. et al.

Source: PLoS Biology. 1/5/2026, Vol. 24 Issue 1, p1-19. 19p.

TDP-43 nuclear loss in FTD/ALS causes widespread alternative polyadenylation changes.

Authors: Zeng Y Lovchykova A Akiyama T et al.

Source: Nature neuroscience [Nat Neurosci] 2025 Nov; Vol. 28 (11), pp. 2180-2189. Date of Electronic Publication: 2025 Oct 21.

Publication Type: Journal Article

Journal Info: Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 9809671 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-1726 (Electronic) Linking ISSN: 10976256 NLM ISO Abbreviation: Nat Neurosci Subsets: MEDLINE

Ubiquitination in the Nervous System: From Molecular Mechanisms to Disease Implications.

Authors: Xue Y Liu X Chen X et al.

Source: Molecular neurobiology [Mol Neurobiol] 2025 Dec; Vol. 62 (12), pp. 15365-15389. Date of Electronic Publication: 2025 Jul 15.

Publication Type: Journal Article; Review

Journal Info: Publisher: Humana Press Country of Publication: United States NLM ID: 8900963 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1559-1182 (Electronic) Linking ISSN: 08937648 NLM ISO Abbreviation: Mol Neurobiol Subsets: MEDLINE

Cyclin F, Neurodegeneration, and the Pathogenesis of ALS/FTD.

Authors: Rayner SL Hogan A Davidson JM et al.

Source: The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry [Neuroscientist] 2024 Apr; Vol. 30 (2), pp. 214-228. Date of Electronic Publication: 2022 Sep 05.

Publication Type: Journal Article; Review; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Sage Publications Country of Publication: United States NLM ID: 9504819 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1089-4098 (Electronic) Linking ISSN: 10738584 NLM ISO Abbreviation: Neuroscientist Subsets: MEDLINE

TDP-43: unveiling the hidden key to cellular fate decisions.

Authors: Liu, Bowen Chen, Xin Wang, Jin et al.

Source: Cell Communication & Signaling. 10/22/2025, Vol. 23 Issue 1, p1-15. 15p.

Epigenetic profiles of tissue informative CpGs inform ALS disease status and progression.

Authors: Caggiano, Christa Morselli, Marco Qian, Xiaoyu et al.

Source: Genome Medicine. 10/16/2025, Vol. 17 Issue 1, p1-20. 20p.

Identification and validation of a tear fluid-derived protein biomarker signature in patients with amyotrophic lateral sclerosis.

Authors: Scholl, Lena-Sophie Demleitner, Antonia F. Riedel, Jenny et al.

Source: Acta Neuropathologica Communications. 9/2/2025, Vol. 13 Issue 1, p1-18. 18p.

Functional constraints of wtf killer meiotic drivers.

Authors: Nidamangala Srinivasa, Ananya Campbell, Samuel Venkatesan, Shriram et al.

Source: PLoS Genetics. 2/18/2025, Vol. 21 Issue 2, p1-41. 41p.

Small peptide CSF fingerprint of amyotrophic lateral sclerosis.

Authors: Lumi, Rea Petri, Susanne Siwy, Justyna et al.

Source: PLoS ONE. 4/30/2024, Vol. 19 Issue 4, p1-13. 13p.

ALS-FTD-linked CCNF^S621G drives increased hippocampal astrocyte ramification and mitochondrial dysfunction and impairs motor neuron excitability.

Authors: Robinson L Do-Ha D Cheng F et al.

Source: Journal of neuroinflammation [J Neuroinflammation] 2026 May 02; Vol. 23 (1). Date of Electronic Publication: 2026 May 02.

Publication Type: Journal Article

Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101222974 Publication Model: Electronic Cited Medium: Internet ISSN: 1742-2094 (Electronic) Linking ISSN: 17422094 NLM ISO Abbreviation: J Neuroinflammation Subsets: MEDLINE

Inhibition of SOD1 trimerization is a novel drug target for ALS disease.

Authors: Woo, Tae-Gyun Han, Jin Kim, Yuju et al.

Source: Translational Neurodegeneration. 5/12/2025, Vol. 14 Issue 1, p1-18. 18p.

Gain-of-function ANXA11 mutation cause late-onset ALS with aberrant protein aggregation, neuroinflammation and autophagy impairment.

Authors: Liu, Qing Sun, Ye He, Baodong et al.

Source: Acta Neuropathologica Communications. 1/4/2025, Vol. 13 Issue 1, p1-18. 18p.

Integrated analysis of transcriptomic and proteomic alterations in mouse models of ALS/FTD identify early metabolic adaptions with similarities to mitochondrial dysfunction disorders.

Authors: Matveeva, Anna Watters, Orla Rukhadze, Ani et al.

Source: Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. Feb2024, Vol. 25 Issue 1/2, p135-149. 15p.

Unbiased Label-Free Quantitative Proteomics of Cells Expressing Amyotrophic Lateral Sclerosis (ALS) Mutations in CCNF Reveals Activation of the Apoptosis Pathway: A Workflow to Screen Pathogenic Gene Mutations.

Authors: Cheng F De Luca A Hogan AL et al.

Source: Frontiers in molecular neuroscience [Front Mol Neurosci] 2021 Apr 27; Vol. 14, pp. 627740. Date of Electronic Publication: 2021 Apr 27 (Print Publication: 2021).

Publication Type: Journal Article

Journal Info: Publisher: Frontiers Research Foundation Country of Publication: Switzerland NLM ID: 101477914 Publication Model: eCollection Cited Medium: Print ISSN: 1662-5099 (Print) Linking ISSN: 16625099 NLM ISO Abbreviation: Front Mol Neurosci Subsets: PubMed not MEDLINE

Genetic enhancers of partial PLK1 inhibition reveal hypersensitivity to kinetochore perturbations.

Authors: Normandin, Karine Coulombe-Huntington, Jasmin St-Denis, Corinne et al.

Source: PLoS Genetics. 8/28/2023, Vol. 19 Issue 8, p1-27. 27p.

ALS/FTD-associated mutation in cyclin F inhibits ER-Golgi trafficking, inducing ER stress, ERAD and Golgi fragmentation.

Authors: Ragagnin, Audrey M. G. Sundaramoorthy, Vinod Farzana, Fabiha et al.

Source: Scientific Reports. 11/22/2023, Vol. 13 Issue 1, p1-20. 20p.

Probe-dependent Proximity Profiling (ProPPr) Uncovers Similarities and Differences in Phospho-Tau-Associated Proteomes Between Tauopathies.

Authors: Morderer, Dmytro Wren, Melissa C. Liu, Feilin et al.

Source: Molecular Neurodegeneration. 3/13/2025, Vol. 20 Issue 1, p1-33. 33p.