Search Results - "Reading CL"

A Potential Role for 5-Androstene-3[beta],7[beta],17[beta]-triol in Obesity and Metabolic Syndrome.

Authors: Auci DL Ahlem CN Kennedy MR et al.

Source: Obesity (19307381). Apr2011, Vol. 19 Issue 4, p806-811.

5-Androstene-3[beta],17[beta]-diol Promotes Recovery of Immature Hematopoietic Cells Following Myelosuppressive Radiation and Synergizes With Thrombopoietin.

Authors: Aerts-Kaya FS Visser TP Arshad S et al.

Source: International Journal of Radiation Oncology, Biology, Physics. Nov2012, Vol. 84 Issue 3, pe401-7. 1p.

Correction: An exploratory analysis of bezisterim treatment associated with decreased biological age acceleration, and improved clinical measure and biomarker changes in mild-to-moderate probable Alzheimer's disease.

Authors: Reading CL Yan J Testa MA et al.

Source: Frontiers in neuroscience [Front Neurosci] 2026 Jan 12; Vol. 19, pp. 1758523. Date of Electronic Publication: 2026 Jan 12 (Print Publication: 2025).

Publication Type: Published Erratum

Journal Info: Publisher: Frontiers Research Foundation Country of Publication: Switzerland NLM ID: 101478481 Publication Model: eCollection Cited Medium: Print ISSN: 1662-4548 (Print) Linking ISSN: 1662453X NLM ISO Abbreviation: Front Neurosci Subsets: PubMed not MEDLINE

An exploratory analysis of bezisterim treatment associated with decreased biological age acceleration, and improved clinical measure and biomarker changes in mild-to-moderate probable Alzheimer's disease.

Authors: Reading CL Yan J Testa MA et al.

Source: Frontiers in neuroscience [Front Neurosci] 2025 May 02; Vol. 19, pp. 1516746. Date of Electronic Publication: 2025 May 02 (Print Publication: 2025).

Publication Type: Journal Article

Journal Info: Publisher: Frontiers Research Foundation Country of Publication: Switzerland NLM ID: 101478481 Publication Model: eCollection Cited Medium: Print ISSN: 1662-4548 (Print) Linking ISSN: 1662453X NLM ISO Abbreviation: Front Neurosci Subsets: PubMed not MEDLINE

NM101 Phase III study of NE3107 in Alzheimer's disease: rationale, design and therapeutic modulation of neuroinflammation and insulin resistance.

Authors: Reading CL Ahlem CN Murphy MF

Source: Neurodegenerative disease management [Neurodegener Dis Manag] 2021 Aug; Vol. 11 (4), pp. 289-298. Date of Electronic Publication: 2021 Jul 12.

Publication Type: Clinical Trial Protocol; Journal Article

Journal Info: Publisher: Taylor & Francis Country of Publication: England NLM ID: 101517977 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1758-2032 (Electronic) Linking ISSN: 17582024 NLM ISO Abbreviation: Neurodegener Dis Manag Subsets: MEDLINE

A synthetic anti-inflammatory sterol improves insulin sensitivity in insulin-resistant obese impaired glucose tolerance subjects.

Authors: Reading CL Stickney DR Flores-Riveros J et al.

Source: Obesity (Silver Spring, Md.) [Obesity (Silver Spring)] 2013 Sep; Vol. 21 (9), pp. E343-9. Date of Electronic Publication: 2013 May 13.

Publication Type: Clinical Trial, Phase I; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't

Journal Info: Publisher: John Wiley & Sons Country of Publication: United States NLM ID: 101264860 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1930-739X (Electronic) Linking ISSN: 19307381 NLM ISO Abbreviation: Obesity (Silver Spring) Subsets: MEDLINE

An anti-inflammatory sterol decreases obesity-related inflammation-induced insulin resistance and metabolic dysregulation.

Authors: Reading CL Flores-Riveros J Stickney DR et al.

Source: Mediators of inflammation [Mediators Inflamm] 2013; Vol. 2013, pp. 814989. Date of Electronic Publication: 2013 Jan 30.

Publication Type: Journal Article; Multicenter Study; Randomized Controlled Trial

Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 9209001 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1466-1861 (Electronic) Linking ISSN: 09629351 NLM ISO Abbreviation: Mediators Inflamm Subsets: MEDLINE

Molecular targets for 17α-ethynyl-5-androstene-3β,7β,17β-triol, an anti-inflammatory agent derived from the human metabolome.

Authors: Reading CL Frincke JM White SK

Source: PloS one [PLoS One] 2012; Vol. 7 (2), pp. e32147. Date of Electronic Publication: 2012 Feb 24.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

HE3286, an oral synthetic steroid, treats lung inflammation in mice without immune suppression.

Authors: Conrad D Wang A Pieters R et al.

Source: Journal of inflammation (London, England) [J Inflamm (Lond)] 2010 Oct 30; Vol. 7, pp. 52. Date of Electronic Publication: 2010 Oct 30.

Publication Type: Journal Article

Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101232234 Publication Model: Electronic Cited Medium: Internet ISSN: 1476-9255 (Electronic) Linking ISSN: 14769255 NLM ISO Abbreviation: J Inflamm (Lond) Subsets: PubMed not MEDLINE

5-Androstene-3β,7β,17β-triol (β-AET) slows thermal injury induced osteopenia in mice: relation to aging and osteoporosis.

Authors: Malik AK Khaldoyanidi S Auci DL et al.

Source: PloS one [PLoS One] 2010 Oct 21; Vol. 5 (10), pp. e13566. Date of Electronic Publication: 2010 Oct 21.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: Electronic Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

16alpha-Bromoepiandrosterone (HE2000) limits non-productive inflammation and stimulates immunity in lungs.

Authors: Nicoletti F Conrad D Wang A et al.

Source: Clinical and experimental immunology [Clin Exp Immunol] 2009 Dec; Vol. 158 (3), pp. 308-16. Date of Electronic Publication: 2009 Sep 30.

Publication Type: Journal Article

Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 0057202 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2249 (Electronic) Linking ISSN: 00099104 NLM ISO Abbreviation: Clin Exp Immunol Subsets: MEDLINE

17α-Ethynyl-androst-5-ene-3β,7β,17β-triol (HE3286) Is Neuroprotective and Reduces Motor Impairment and Neuroinflammation in a Murine MPTP Model of Parkinson's Disease.

Authors: Nicoletti F Philippens I Fagone P et al.

Source: Parkinson's disease [Parkinsons Dis] 2012; Vol. 2012, pp. 969418. Date of Electronic Publication: 2012 Sep 26.

Publication Type: Journal Article

Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 101539877 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2042-0080 (Electronic) Linking ISSN: 20420080 NLM ISO Abbreviation: Parkinsons Dis Subsets: PubMed not MEDLINE

Pharmacology and immune modulating properties of 5-androstene-3β,7β,17β-triol, a DHEA metabolite in the human metabolome.

Authors: Ahlem CN Auci DL Nicoletti F et al.

Source: The Journal of steroid biochemistry and molecular biology [J Steroid Biochem Mol Biol] 2011 Sep; Vol. 126 (3-5), pp. 87-94. Date of Electronic Publication: 2011 May 05.

Publication Type: Evaluation Study; Journal Article

Journal Info: Publisher: Pergamon Country of Publication: England NLM ID: 9015483 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-1220 (Electronic) Linking ISSN: 09600760 NLM ISO Abbreviation: J Steroid Biochem Mol Biol Subsets: MEDLINE

Phase I and Phase II clinical trials of androst-5-ene-3β,7β,17β-triol.

Authors: Stickney DR Ahlem CN Morgan E et al.

Source: American journal of translational research [Am J Transl Res] 2011 May 15; Vol. 3 (3), pp. 275-83. Date of Electronic Publication: 2011 Apr 12.

Publication Type: Journal Article

Journal Info: Publisher: e-Century Pub. Corp Country of Publication: United States NLM ID: 101493030 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1943-8141 (Electronic) Linking ISSN: 19438141 NLM ISO Abbreviation: Am J Transl Res Subsets: PubMed not MEDLINE

HE3286, an orally bioavailable synthetic analogue of an active DHEA metabolite suppresses spontaneous autoimmune diabetes in the non-obese diabetic (NOD) mouse.

Authors: Kosiewicz MM Auci DL Fagone P et al.

Source: European journal of pharmacology [Eur J Pharmacol] 2011 May 11; Vol. 658 (2-3), pp. 257-62. Date of Electronic Publication: 2011 Mar 01.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 1254354 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0712 (Electronic) Linking ISSN: 00142999 NLM ISO Abbreviation: Eur J Pharmacol Subsets: MEDLINE

17α-ethynyl-5α-androstane-3α, 17β-diol treatment of MNU-induced mammary cancer in rats.

Authors: Ahlem CN Frincke JM White SK et al.

Source: International journal of breast cancer [Int J Breast Cancer] 2011; Vol. 2011, pp. 618757. Date of Electronic Publication: 2011 Feb 14.

Publication Type: Journal Article

Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 101568103 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2090-3189 (Electronic) Linking ISSN: 20903189 NLM ISO Abbreviation: Int J Breast Cancer Subsets: PubMed not MEDLINE

Novel components of the human metabolome: the identification, characterization and anti-inflammatory activity of two 5-androstene tetrols.

Authors: Ahlem CN Page TM Auci DL et al.

Source: Steroids [Steroids] 2011 Jan; Vol. 76 (1-2), pp. 145-55. Date of Electronic Publication: 2010 Oct 23.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 0404536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-5867 (Electronic) Linking ISSN: 0039128X NLM ISO Abbreviation: Steroids Subsets: MEDLINE

Studies of the pharmacology of 17α-ethynyl-androst-5-ene-3β,7β,17β-triol, a synthetic anti-inflammatory androstene.

Authors: Ahlem CN Kennedy MR Page TM et al.

Source: International journal of clinical and experimental medicine [Int J Clin Exp Med] 2011; Vol. 4 (2), pp. 119-35. Date of Electronic Publication: 2011 Apr 23.

Publication Type: Journal Article

Journal Info: Publisher: e-Century Pub. Corp Country of Publication: United States NLM ID: 101471010 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1940-5901 (Electronic) Linking ISSN: 19405901 NLM ISO Abbreviation: Int J Clin Exp Med Subsets: PubMed not MEDLINE

5-androstenediol ameliorates pleurisy, septic shock, and experimental autoimmune encephalomyelitis in mice.

Authors: Nicoletti F Auci DL Mangano K et al.

Source: Autoimmune diseases [Autoimmune Dis] 2010 May 18; Vol. 2010, pp. 757432. Date of Electronic Publication: 2010 May 18.

Publication Type: Journal Article

Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 101546750 Publication Model: Electronic Cited Medium: Internet ISSN: 2090-0430 (Electronic) Linking ISSN: 20900430 NLM ISO Abbreviation: Autoimmune Dis Subsets: PubMed not MEDLINE

Oral treatment with HE3286 ameliorates disease in rodent models of rheumatoid arthritis.

Authors: Auci DL Mangano K Destiche D et al.

Source: International journal of molecular medicine [Int J Mol Med] 2010 Apr; Vol. 25 (4), pp. 625-33.

Publication Type: Journal Article

Journal Info: Publisher: D.A. Spandidos Country of Publication: Greece NLM ID: 9810955 Publication Model: Print Cited Medium: Internet ISSN: 1791-244X (Electronic) Linking ISSN: 11073756 NLM ISO Abbreviation: Int J Mol Med Subsets: MEDLINE