Search Results - "Replication fork"

DMAP1 Deficiency Suppresses Lung Cancer Progression by Destabilizing Replication Fork and Activating IFN Signaling‐Mediated Anti‐tumor Immunity.

Authors: Huang, Kan Dai, Xi Li, Shuaihu et al.

Source: Advanced Science. 6/15/2026, Vol. 13 Issue 33, p1-20. 20p.

Benzofuran-Annulated Naphthalimides Trigger Replication Stress, DNA Damage, and p53-Dependent Cell Cycle Arrest.

Authors: Vlahova, Zlatina Lazarov, Lazar Petrova, Maria et al.

Source: Pharmaceutics. Jun2026, Vol. 18 Issue 6, p754. 26p.

HNF1B integrates signals in a feed-forward loop driving kidney disease progression.

Authors: Isnard, Pierre Makinistoglu, Munevver Parla Leibovici, Michel et al.

Source: Science. 4/16/2026, Vol. 392 Issue 6795, p1-15. 15p.

Subjects: Hepatocyte nuclear factors, Transcription factors, Replication fork, Chronic kidney failure, Renal fibrosis, Kidney tubules, Cell cycle, Epigenetics

The RPA-binding domain and the KKRK motif in Rad26^ATRIP cooperate at the perturbed DNA replication fork for initiating checkpoint signalling.

Authors: Xu, Yong-jie Gao, Anmin Dev, Kamal et al.

Source: PLoS Genetics. 2/23/2026, Vol. 22 Issue 2, p1-21. 21p.

Benzodioxin-Annulated Naphthalimides as Potent DNA Replication Stress Inducers with Dual p53-Dependent and Independent Antitumor Activity.

Authors: Vlahova, Zlatina Lazarov, Lazar Petrova, Maria et al.

Source: Pharmaceutics. Feb2026, Vol. 18 Issue 2, p167. 29p.

Srcap Chromatin Remodeler Is Required for Efficient Replication Dynamics in Mammalian Cells.

Authors: Dzhokova, Stefka K. Hristova, Rossitsa H. Botev, Peter S. et al.

Source: International Journal of Molecular Sciences. Dec2025, Vol. 26 Issue 24, p12189. 15p.

Stn1 supports Mec1 function in protecting stalled replication forks from degradation.

Authors: Casari, Erika Corallo, Flavio Milani, Luca Edoardo et al.

Source: PLoS Genetics. 10/15/2025, Vol. 21 Issue 10, p1-26. 26p.

Regulation of replication timing in Saccharomyces cerevisiae.

Authors: Berners-Lee, Rosie Gilmore, Eamonn Berkemeier, Francisco et al.

Source: PLoS Computational Biology. 6/2/2025, Vol. 21 Issue 6, p1-18. 18p.

At the fork: where epigenetic decisions are made.

Authors: Jia, Songtao¹ (AUTHOR) songtao.jia@columbia.edu

Source: Trends in Genetics. Jul2026, Vol. 42 Issue 7, p606-617. 12p.

Replication-stress-induced chromatin loops protect fork stability.

Authors: Gaggioli, Vincent Sengupta, Kaustav Choudhury, Ashutosh et al.

Source: Nature. Jul2026, p1-13. 13p.

SLX4IP limits replication stress globally and at ALT telomeres.

Authors: Spindler, Jessica Pandolfo, Francesca Koch, Anna Eva et al.

Source: EMBO Journal. Jun2026, Vol. 45 Issue 12, p4176-4219. 44p.

複製フォークにおけるヒストン H3/H4 リサイ クリングの分子メカニズム.

Alternate Title: Molecular Mechanism of Histone H3/H4 Tetramer Recycling at a Replication Fork.

Authors: 長江文立津 村山泰斗 寺川剛

Source: Seibutsu Butsuri. 2025, Vol. 65 Issue 6, p315-317. 3p.

The Slx4-Rad1-Rad10 nuclease differentially regulates deletions and duplications induced by a replication fork barrier.

Authors: Triplett, Marina K Ahmed, Iffat Shekharan, Swathi et al.

Source: PLoS Genetics. 5/30/2025, Vol. 21 Issue 5, p1-26. 26p.

Co-inhibition of Notch1 and ChK1 triggers genomic instability and melanoma cell death increasing the lifespan of mice bearing melanoma brain metastasis.

Authors: Thakur, Varsha Thakur, Vijay S. Wang, Dazhi et al.

Source: Journal of Experimental & Clinical Cancer Research (17569966). 5/28/2025, Vol. 44 Issue 1, p1-13. 13p.

Targeting Replication Fork Processing Synergizes with PARP Inhibition to Potentiate Lethality in Homologous Recombination Proficient Ovarian Cancers.

Authors: Pai Bellare, Ganesh Kundu, Kshama Dey, Papiya et al.

Source: Advanced Science. 5/15/2025, Vol. 12 Issue 18, p1-24. 24p.

DNA glycosylase (NEIL3) overexpression associated with low tumor immune infiltration and poor overall patient survival in endometrial cancer.

Authors: Barry, Cristofer Shahi, Aashirwad Kidane, Dawit

Source: Scientific Reports. 5/10/2025, Vol. 15 Issue 1, p1-10. 10p.

A Rfa1-MN–based system reveals new factors involved in the rescue of broken replication forks.

Authors: Amiama-Roig, Ana Barrientos-Moreno, Marta Cruz-Zambrano, Esther et al.

Source: PLoS Genetics. 4/1/2025, Vol. 21 Issue 4, p1-27. 27p.

RPA-independent activation of the ATR/CHK1 pathway.

Authors: Huang, Min Zhu, Dandan Chen, Junjie

Source: Proceedings of the National Academy of Sciences of the United States of America. 2/10/2026, Vol. 123 Issue 6, p1-10. 22p.

Subjects: Replication fork, Serine/threonine kinases, DNA repair, DNA damage, Cellular signal transduction

RecBCD-dependent post-UV replication restart in Escherichia coli triggers fork triplication.

Authors: Kouzminovaa, Elena A. Cronan, Glen E. Kuzminov, Andrei

Source: Proceedings of the National Academy of Sciences of the United States of America. 1/27/2026, Vol. 123 Issue 4, p1-12. 34p.

Subjects: Replication fork, DNA replication, Ultraviolet radiation, DNA repair, Escherichia coli, Homologous recombination

The bacterial MRE11–RAD50 and DNA2–WRN homologs process replication forks at distinct and separate loci on the chromosome.

Authors: Spolek, Raymond L. Christian, Paden Y. H. Courcelle, Charmain T. et al.

Source: FEBS Letters. Feb2026, Vol. 600 Issue 4, p451-466. 16p.

Subjects: Replication fork, Locus (Genetics), BRCA genes, DNA repair, Bacteria, Genetic mutation, Double-strand DNA breaks