Search Results - "Replogle JM"

Neurodegeneration risk variants promote lysosomal TMEM106B fibril accumulation.

Authors: Replogle JM Marks JD Fernandez MG et al.

Source: BioRxiv : the preprint server for biology [bioRxiv] 2026 Mar 28. Date of Electronic Publication: 2026 Mar 28.

Publication Type: Journal Article; Preprint

Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

Transcriptome-wide analysis of differential expression in perturbation atlases.

Authors: Nadig A Replogle JM Pogson AN et al.

Source: Nature genetics [Nat Genet] 2025 May; Vol. 57 (5), pp. 1228-1237. Date of Electronic Publication: 2025 Apr 21.

Publication Type: Journal Article

Journal Info: Publisher: Nature Pub. Co Country of Publication: United States NLM ID: 9216904 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-1718 (Electronic) Linking ISSN: 10614036 NLM ISO Abbreviation: Nat Genet Subsets: MEDLINE

A dual sgRNA library design to probe genetic modifiers using genome-wide CRISPRi screens.

Authors: Guna A Page KR Replogle JM et al.

Source: BMC genomics [BMC Genomics] 2023 Oct 30; Vol. 24 (1), pp. 651. Date of Electronic Publication: 2023 Oct 30.

Publication Type: Journal Article

Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 100965258 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2164 (Electronic) Linking ISSN: 14712164 NLM ISO Abbreviation: BMC Genomics Subsets: MEDLINE

Systematic functional interrogation of SARS-CoV-2 host factors using Perturb-seq.

Authors: Sunshine S Puschnik AS Replogle JM et al.

Source: Nature communications [Nat Commun] 2023 Oct 06; Vol. 14 (1), pp. 6245. Date of Electronic Publication: 2023 Oct 06.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

Maximizing CRISPRi efficacy and accessibility with dual-sgRNA libraries and optimal effectors.

Authors: Replogle JM Bonnar JL Pogson AN et al.

Source: ELife [Elife] 2022 Dec 28; Vol. 11. Date of Electronic Publication: 2022 Dec 28.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Extramural

Journal Info: Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic Cited Medium: Internet ISSN: 2050-084X (Electronic) Linking ISSN: 2050084X NLM ISO Abbreviation: Elife Subsets: MEDLINE

MTCH2 is a mitochondrial outer membrane protein insertase.

Authors: Guna A Stevens TA Inglis AJ et al.

Source: Science (New York, N.Y.) [Science] 2022 Oct 21; Vol. 378 (6617), pp. 317-322. Date of Electronic Publication: 2022 Oct 20.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE

Nucleotide depletion promotes cell fate transitions by inducing DNA replication stress.

Authors: Do BT Hsu PP Vermeulen SY et al.

Source: Developmental cell [Dev Cell] 2024 Aug 19; Vol. 59 (16), pp. 2203-2221.e15. Date of Electronic Publication: 2024 May 31.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101120028 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-1551 (Electronic) Linking ISSN: 15345807 NLM ISO Abbreviation: Dev Cell Subsets: MEDLINE

Transcriptome-wide characterization of genetic perturbations.

Authors: Nadig A Replogle JM Pogson AN et al.

Source: BioRxiv : the preprint server for biology [bioRxiv] 2024 Jul 03. Date of Electronic Publication: 2024 Jul 03.

Publication Type: Journal Article; Preprint

Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

Rapid deployment of SARS-CoV-2 testing: The CLIAHUB.

Authors: Crawford ED Acosta I Ahyong V et al.

Source: PLoS pathogens [PLoS Pathog] 2020 Oct 28; Vol. 16 (10), pp. e1008966. Date of Electronic Publication: 2020 Oct 28 (Print Publication: 2020).

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7374 (Electronic) Linking ISSN: 15537366 NLM ISO Abbreviation: PLoS Pathog Subsets: MEDLINE

Microfluidics-free single-cell genomics with templated emulsification.

Authors: Clark IC Fontanez KM Meltzer RH et al.

Source: Nature biotechnology [Nat Biotechnol] 2023 Nov; Vol. 41 (11), pp. 1557-1566. Date of Electronic Publication: 2023 Mar 06.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

Journal Info: Publisher: Nature America Publishing Country of Publication: United States NLM ID: 9604648 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-1696 (Electronic) Linking ISSN: 10870156 NLM ISO Abbreviation: Nat Biotechnol Subsets: MEDLINE

Author Correction: Efficient C•G-to-G•C base editors developed using CRISPRi screens, target-library analysis, and machine learning.

Authors: Koblan LW Arbab M Shen MW et al.

Source: Nature biotechnology [Nat Biotechnol] 2023 Nov; Vol. 41 (11), pp. 1655.

Publication Type: Published Erratum

Journal Info: Publisher: Nature America Publishing Country of Publication: United States NLM ID: 9604648 Publication Model: Print Cited Medium: Internet ISSN: 1546-1696 (Electronic) Linking ISSN: 10870156 NLM ISO Abbreviation: Nat Biotechnol Subsets: MEDLINE; PubMed not MEDLINE

A dual sgRNA library design to probe genetic modifiers using genome-wide CRISPRi screens.

Authors: Guna A Page KR Replogle JM et al.

Source: BioRxiv : the preprint server for biology [bioRxiv] 2023 Aug 14. Date of Electronic Publication: 2023 Aug 14.

Publication Type: Preprint; Journal Article

Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

Exploring genetic interaction manifolds constructed from rich single-cell phenotypes.

Authors: Norman TM Horlbeck MA Replogle JM et al.

Source: Science (New York, N.Y.) [Science] 2019 Aug 23; Vol. 365 (6455), pp. 786-793. Date of Electronic Publication: 2019 Aug 08.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE

Dual genome-wide coding and lncRNA screens in neural induction of induced pluripotent stem cells.

Authors: Wu D Poddar A Ninou E et al.

Source: Cell genomics [Cell Genom] 2022 Nov 09; Vol. 2 (11). Date of Electronic Publication: 2022 Sep 14.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier, Inc Country of Publication: United States NLM ID: 9918284260106676 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2666-979X (Electronic) Linking ISSN: 2666979X NLM ISO Abbreviation: Cell Genom Subsets: PubMed not MEDLINE

A human microglia-like cellular model for assessing the effects of neurodegenerative disease gene variants.

Authors: Ryan KJ White CC Patel K et al.

Source: Science translational medicine [Sci Transl Med] 2017 Dec 20; Vol. 9 (421).

Publication Type: Journal Article

Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE

Mapping information-rich genotype-phenotype landscapes with genome-scale Perturb-seq.

Authors: Replogle JM Saunders RA Pogson AN et al.

Source: Cell [Cell] 2022 Jul 07; Vol. 185 (14), pp. 2559-2575.e28. Date of Electronic Publication: 2022 Jun 09.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 0413066 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4172 (Electronic) Linking ISSN: 00928674 NLM ISO Abbreviation: Cell Subsets: MEDLINE

Lineage tracing reveals the phylodynamics, plasticity, and paths of tumor evolution.

Authors: Yang D Jones MG Naranjo S et al.

Source: Cell [Cell] 2022 May 26; Vol. 185 (11), pp. 1905-1923.e25. Date of Electronic Publication: 2022 May 05.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 0413066 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4172 (Electronic) Linking ISSN: 00928674 NLM ISO Abbreviation: Cell Subsets: MEDLINE

Mapping transcriptomic vector fields of single cells.

Authors: Qiu X Zhang Y Martin-Rufino JD et al.

Source: Cell [Cell] 2022 Feb 17; Vol. 185 (4), pp. 690-711.e45. Date of Electronic Publication: 2022 Feb 01.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 0413066 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4172 (Electronic) Linking ISSN: 00928674 NLM ISO Abbreviation: Cell Subsets: MEDLINE

Efficient C•G-to-G•C base editors developed using CRISPRi screens, target-library analysis, and machine learning.

Authors: Koblan LW Arbab M Shen MW et al.

Source: Nature biotechnology [Nat Biotechnol] 2021 Nov; Vol. 39 (11), pp. 1414-1425. Date of Electronic Publication: 2021 Jun 28.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

Journal Info: Publisher: Nature America Publishing Country of Publication: United States NLM ID: 9604648 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-1696 (Electronic) Linking ISSN: 10870156 NLM ISO Abbreviation: Nat Biotechnol Subsets: MEDLINE

Nucleosomes impede Cas9 access to DNA in vivo and in vitro.

Authors: Horlbeck MA Witkowsky LB Guglielmi B et al.

Source: ELife [Elife] 2016 Mar 17; Vol. 5. Date of Electronic Publication: 2016 Mar 17.

Publication Type: Journal Article

Journal Info: Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic Cited Medium: Internet ISSN: 2050-084X (Electronic) Linking ISSN: 2050084X NLM ISO Abbreviation: Elife Subsets: MEDLINE