Search Results - "Reverse transcriptase"

Clearance of NNRTI resistance-associated mutations in the HIV-1 DNA reservoir with or without the presence of M184V mutation.

Authors: Soulie C Zafilaza K Wirden M et al.

Source: The Journal of antimicrobial chemotherapy [J Antimicrob Chemother] 2026 Jul 02; Vol. 81 (8).

Publication Type: Journal Article

Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 7513617 Publication Model: Print Cited Medium: Internet ISSN: 1460-2091 (Electronic) Linking ISSN: 03057453 NLM ISO Abbreviation: J Antimicrob Chemother Subsets: MEDLINE

New potential HIV-1 inhibitors, analogues to efavirenz, containing the isatin core.

Authors: Machado GP Costa PAG Leite DI et al.

Source: Bioorganic & medicinal chemistry [Bioorg Med Chem] 2026 Aug; Vol. 139, pp. 118685. Date of Electronic Publication: 2026 May 02.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Science Country of Publication: England NLM ID: 9413298 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1464-3391 (Electronic) Linking ISSN: 09680896 NLM ISO Abbreviation: Bioorg Med Chem Subsets: MEDLINE

Characterisation of RT Connection and RNase H Polymorphisms in HIV-1 Subtype C in Botswana.

Authors: Zuze BJL Choga WT Moraka-Mankge NO et al.

Source: Viruses [Viruses] 2026 Apr 03; Vol. 18 (4). Date of Electronic Publication: 2026 Apr 03.

Publication Type: Journal Article

Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101509722 Publication Model: Electronic Cited Medium: Internet ISSN: 1999-4915 (Electronic) Linking ISSN: 19994915 NLM ISO Abbreviation: Viruses Subsets: MEDLINE

Harnessing machine learning models to repurpose drugs targeting HIV-1 integrase, protease, and reverse transcriptase.

Authors: Chirila CB Crisan L

Source: Scientific reports [Sci Rep] 2026 Apr 19; Vol. 16 (1). Date of Electronic Publication: 2026 Apr 19.

Publication Type: Journal Article

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

Synthesis and functional characterization of a recombinant HIV-1 reverse transcriptase variant carrying twelve drug-resistance mutations as a platform for antiretroviral screening.

Authors: Dos Santos-Filho TJ Vazquez L Chaves OA et al.

Source: International journal of biological macromolecules [Int J Biol Macromol] 2026 Mar; Vol. 349, pp. 150723. Date of Electronic Publication: 2026 Feb 05.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7909578 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0003 (Electronic) Linking ISSN: 01418130 NLM ISO Abbreviation: Int J Biol Macromol Subsets: MEDLINE

Deciphering the enigmas of non-nucleoside reverse transcriptase inhibitors (NNRTIs): A medicinal chemistry expedition towards combating HIV drug resistance.

Authors: Zhang K Zhang YJ Li M et al.

Source: Medicinal research reviews [Med Res Rev] 2025 Mar; Vol. 45 (2), pp. 426-483. Date of Electronic Publication: 2024 Aug 26.

Publication Type: Journal Article; Review; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 8103150 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1098-1128 (Electronic) Linking ISSN: 01986325 NLM ISO Abbreviation: Med Res Rev Subsets: MEDLINE

High prevalence of reverse transcriptase inhibitors associated resistance mutations among people living with HIV on dolutegravir-based antiretroviral therapy in Francistown, Botswana.

Authors: Choga OT Lemogang GM Choga WT et al.

Source: The Journal of antimicrobial chemotherapy [J Antimicrob Chemother] 2025 Mar 03; Vol. 80 (3), pp. 767-776.

Publication Type: Journal Article

Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 7513617 Publication Model: Print Cited Medium: Internet ISSN: 1460-2091 (Electronic) Linking ISSN: 03057453 NLM ISO Abbreviation: J Antimicrob Chemother Subsets: MEDLINE

Drug resistance mutations to integrase inhibitors, proteinase, and reverse transcriptase inhibitors in newly diagnosed HIV-1 infections in Hebei province, China, 2018-2022.

Authors: Lu X Li Y Liu M et al.

Source: Frontiers in cellular and infection microbiology [Front Cell Infect Microbiol] 2025 Feb 24; Vol. 15, pp. 1510916. Date of Electronic Publication: 2025 Feb 24 (Print Publication: 2025).

Publication Type: Journal Article

Journal Info: Publisher: Frontiers Media SA Country of Publication: Switzerland NLM ID: 101585359 Publication Model: eCollection Cited Medium: Internet ISSN: 2235-2988 (Electronic) Linking ISSN: 22352988 NLM ISO Abbreviation: Front Cell Infect Microbiol Subsets: MEDLINE

Design, Synthesis, Biological Evaluation and Molecular Docking Studies of New Thiazolidinone Derivatives as NNRTIs and SARS-CoV-2 Main Protease Inhibitors.

Authors: Fesatidou M Petrou A Geronikaki A

Source: Chemistry & biodiversity [Chem Biodivers] 2024 Dec; Vol. 21 (12), pp. e202401697. Date of Electronic Publication: 2024 Oct 23.

Publication Type: Journal Article

Journal Info: Publisher: Verlag Helvetica Chimica Acta Country of Publication: Switzerland NLM ID: 101197449 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1612-1880 (Electronic) Linking ISSN: 16121872 NLM ISO Abbreviation: Chem Biodivers Subsets: MEDLINE

Changes in NNRTI use have not altered the ecology of NNRTI resistance over the last 10 years in people with HIV experiencing virological failure on antiretroviral drugs.

Authors: Soulie C Agher R Fauchois A et al.

Source: The Journal of antimicrobial chemotherapy [J Antimicrob Chemother] 2025 Mar 03; Vol. 80 (3), pp. 697-700.

Publication Type: Journal Article

Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 7513617 Publication Model: Print Cited Medium: Internet ISSN: 1460-2091 (Electronic) Linking ISSN: 03057453 NLM ISO Abbreviation: J Antimicrob Chemother Subsets: MEDLINE

Prognostic Value of PCR Cycle Threshold Value in Crimean-Congo Hemorrhagic Fever, Iraq, 2022-2023.

Authors: Khaleel RI Aakef IR Al-Hilfi RA et al.

Source: Emerging infectious diseases [Emerg Infect Dis] 2026 Jul; Vol. 32 (7), pp. 1104-1112.

Publication Type: Journal Article

Journal Info: Publisher: National Center for Infectious Diseases, Centers for Disease Control and Prevention (CDC) Country of Publication: United States NLM ID: 9508155 Publication Model: Print Cited Medium: Internet ISSN: 1080-6059 (Electronic) Linking ISSN: 10806040 NLM ISO Abbreviation: Emerg Infect Dis Subsets: MEDLINE

HIV-1 genetic diversity and reverse transcriptase resistance mutations in Benin before dolutegravir era, West Africa.

Authors: Tchiakpe E Keke RK Recordon-Pinson P et al.

Source: PloS one [PLoS One] 2026 May 21; Vol. 21 (5), pp. e0348800. Date of Electronic Publication: 2026 May 21 (Print Publication: 2026).

Publication Type: Journal Article

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

A new strategy based on drug-linker-nanocarrier interactions to design new HIV-1 non-nucleoside reverse transcriptase inhibitors.

Authors: Yoosefian M Mirhaji E Esmaeili A

Source: Journal of biomolecular structure & dynamics [J Biomol Struct Dyn] 2026 Feb; Vol. 44 (2), pp. 797-808. Date of Electronic Publication: 2025 May 24.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Taylor & Francis Country of Publication: England NLM ID: 8404176 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-0254 (Electronic) Linking ISSN: 07391102 NLM ISO Abbreviation: J Biomol Struct Dyn Subsets: MEDLINE

Data mining and molecular dynamics analysis to detect HIV-1 reverse transcriptase RNase H activity inhibitor.

Authors: Ghafoor NA Kırboğa KK Baysal Ö et al.

Source: Molecular diversity [Mol Divers] 2024 Aug; Vol. 28 (4), pp. 1869-1888. Date of Electronic Publication: 2023 Aug 10.

Publication Type: Journal Article

Journal Info: Publisher: ESCOM Science Publishers Country of Publication: Netherlands NLM ID: 9516534 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-501X (Electronic) Linking ISSN: 13811991 NLM ISO Abbreviation: Mol Divers Subsets: MEDLINE

REverse transcriptase ACTivity (REACT) assay for point-of-care measurement of established and emerging antiretrovirals for HIV treatment and prevention.

Authors: Brainerd C Singh MA Tatka J et al.

Source: Analytical and bioanalytical chemistry [Anal Bioanal Chem] 2024 Dec; Vol. 416 (29), pp. 6809-6818. Date of Electronic Publication: 2024 Oct 28.

Publication Type: Journal Article

Journal Info: Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 101134327 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1618-2650 (Electronic) Linking ISSN: 16182642 NLM ISO Abbreviation: Anal Bioanal Chem Subsets: MEDLINE

Structure-based design, synthesis, and biological characterization of indolylarylsulfone derivatives as novel human immunodeficiency virus type 1 inhibitors with potent antiviral activities and favorable drug-like profiles.

Authors: Wang Z Wang W Gao Z et al.

Source: Journal of medical virology [J Med Virol] 2024 Aug; Vol. 96 (8), pp. e29830.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 7705876 Publication Model: Print Cited Medium: Internet ISSN: 1096-9071 (Electronic) Linking ISSN: 01466615 NLM ISO Abbreviation: J Med Virol Subsets: MEDLINE

In Silico Studies of the Hepatitis B Virus Polymerase: Efforts to Identify Novel Drug Binding Sites to Inhibit HBV Replication.

Authors: Tajwar R Li Q Tavis JE

Source: Missouri medicine [Mo Med] 2026 Mar-Apr; Vol. 123 (2), pp. 149-155.

Publication Type: Journal Article

Journal Info: Publisher: Missouri State Medical Association Country of Publication: United States NLM ID: 0400744 Publication Model: Print Cited Medium: Internet ISSN: 0026-6620 (Print) Linking ISSN: 00266620 NLM ISO Abbreviation: Mo Med Subsets: MEDLINE

Discovery and molecular docking studies of nitrogen containing naphthyridine derivatives as potent HIV1 NNRTIs with anticancer potential.

Authors: Baicharoen A Vijitphan P Patnin S et al.

Source: Scientific reports [Sci Rep] 2025 Oct 01; Vol. 15 (1), pp. 32622. Date of Electronic Publication: 2025 Oct 01.

Publication Type: Journal Article

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

Acquired HIV-1 drug resistance to reverse transcriptase and protease inhibitors among people failing antiretroviral therapy in Cameroon and implications for future treatment options.

Authors: Fokam J Anim-Keng TT Pokam BT et al.

Source: AIDS research and therapy [AIDS Res Ther] 2025 Sep 30; Vol. 22 (1), pp. 97. Date of Electronic Publication: 2025 Sep 30.

Publication Type: Journal Article

Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101237921 Publication Model: Electronic Cited Medium: Internet ISSN: 1742-6405 (Electronic) Linking ISSN: 17426405 NLM ISO Abbreviation: AIDS Res Ther Subsets: MEDLINE

Reference gene selection for RT-qPCR normalization in the drone testis of honey bee (Apis cerana) during meiosis stages.

Authors: Tao L Fu X Pang C et al.

Source: PloS one [PLoS One] 2026 Apr 09; Vol. 21 (4), pp. e0347110. Date of Electronic Publication: 2026 Apr 09 (Print Publication: 2026).

Publication Type: Journal Article

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE