Search Results - "Rutter JC"

Metabolic control of innate immune activation in TET2-mutant clonal hematopoiesis.

Authors: Kim PG Hergott CB Miller AP et al.

Source: Cell chemical biology [Cell Chem Biol] 2026 Feb 19; Vol. 33 (2), pp. 183-197.e9. Date of Electronic Publication: 2026 Feb 10.

Publication Type: Journal Article

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101676030 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2451-9448 (Electronic) Linking ISSN: 24519448 NLM ISO Abbreviation: Cell Chem Biol Subsets: MEDLINE

Mediator kinase inhibition impedes transcriptional plasticity and prevents resistance to ERK/MAPK-targeted therapy in KRAS-mutant cancers.

Authors: Nussbaum DP Martz CA Waters AM et al.

Source: NPJ precision oncology [NPJ Precis Oncol] 2024 May 31; Vol. 8 (1), pp. 124. Date of Electronic Publication: 2024 May 31.

Publication Type: Journal Article

Journal Info: Publisher: Springer Nature Country of Publication: England NLM ID: 101708166 Publication Model: Electronic Cited Medium: Print ISSN: 2397-768X (Print) Linking ISSN: 2397768X NLM ISO Abbreviation: NPJ Precis Oncol Subsets: PubMed not MEDLINE

PitViper: a software for comparative meta-analysis and annotation of functional screening data.

Authors: Meslin PA Kelly LM Benbarche S et al.

Source: NAR genomics and bioinformatics [NAR Genom Bioinform] 2024 May 25; Vol. 6 (2), pp. lqae059. Date of Electronic Publication: 2024 May 25 (Print Publication: 2024).

Publication Type: Journal Article

Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 101756213 Publication Model: eCollection Cited Medium: Internet ISSN: 2631-9268 (Electronic) Linking ISSN: 26319268 NLM ISO Abbreviation: NAR Genom Bioinform Subsets: PubMed not MEDLINE

A heterotrimeric protein complex assembles the metazoan V-ATPase upon dissipation of proton gradients.

Authors: Nardone C Mintseris J He D et al.

Source: Nature structural & molecular biology [Nat Struct Mol Biol] 2025 Oct; Vol. 32 (10), pp. 2076-2087. Date of Electronic Publication: 2025 Jul 11.

Publication Type: Journal Article

Journal Info: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101186374 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1545-9985 (Electronic) Linking ISSN: 15459985 NLM ISO Abbreviation: Nat Struct Mol Biol Subsets: MEDLINE

Discovery of chromatin-based determinants of azacytidine and decitabine anti-cancer activity.

Authors: Puram RV Yin Q Liu Y et al.

Source: BioRxiv : the preprint server for biology [bioRxiv] 2025 Aug 01. Date of Electronic Publication: 2025 Aug 01.

Publication Type: Journal Article; Preprint

Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

Stability and DNA Methyltransferase Activity of DNMT3A are Maintained by Ubiquitin-Specific Peptidase 11 (USP11) and Sumoylation Countering Degradation.

Authors: Yonezawa T Rutter JC Ramabadran R et al.

Source: BioRxiv : the preprint server for biology [bioRxiv] 2025 Jun 27. Date of Electronic Publication: 2025 Jun 27.

Publication Type: Journal Article; Preprint

Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

Exploration of the tunability of BRD4 degradation by DCAF16 trans-labelling covalent glues.

Authors: Hassan MM Li YD Ma MW et al.

Source: European journal of medicinal chemistry [Eur J Med Chem] 2024 Dec 05; Vol. 279, pp. 116904. Date of Electronic Publication: 2024 Sep 24.

Publication Type: Journal Article

Journal Info: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1768-3254 (Electronic) Linking ISSN: 02235234 NLM ISO Abbreviation: Eur J Med Chem Subsets: MEDLINE

Template-assisted covalent modification underlies activity of covalent molecular glues.

Authors: Li YD Ma MW Hassan MM et al.

Source: Nature chemical biology [Nat Chem Biol] 2024 Dec; Vol. 20 (12), pp. 1640-1649. Date of Electronic Publication: 2024 Jul 29.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S.

Journal Info: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101231976 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1552-4469 (Electronic) Linking ISSN: 15524450 NLM ISO Abbreviation: Nat Chem Biol Subsets: MEDLINE

Targeting a lineage-specific PI3Kɣ-Akt signaling module in acute myeloid leukemia using a heterobifunctional degrader molecule.

Authors: Kelly LM Rutter JC Lin KH et al.

Source: Nature cancer [Nat Cancer] 2024 Jul; Vol. 5 (7), pp. 1082-1101. Date of Electronic Publication: 2024 May 30.

Publication Type: Journal Article

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101761119 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2662-1347 (Electronic) Linking ISSN: 26621347 NLM ISO Abbreviation: Nat Cancer Subsets: MEDLINE

Induced protein degradation for therapeutics: past, present, and future.

Authors: Yoon H Rutter JC Li YD et al.

Source: The Journal of clinical investigation [J Clin Invest] 2024 Jan 02; Vol. 134 (1). Date of Electronic Publication: 2024 Jan 02.

Publication Type: Journal Article; Review; Research Support, N.I.H., Extramural

Journal Info: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model: Electronic Cited Medium: Internet ISSN: 1558-8238 (Electronic) Linking ISSN: 00219738 NLM ISO Abbreviation: J Clin Invest Subsets: MEDLINE

Exploration of the Tunability of BRD4 Degradation by DCAF16 Trans-labelling Covalent Glues.

Authors: Hassan MM Li YD Ma MW et al.

Source: BioRxiv : the preprint server for biology [bioRxiv] 2023 Oct 10. Date of Electronic Publication: 2023 Oct 10.

Publication Type: Preprint; Journal Article

Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

UBR5 forms ligand-dependent complexes on chromatin to regulate nuclear hormone receptor stability.

Authors: Tsai JM Aguirre JD Li YD et al.

Source: Molecular cell [Mol Cell] 2023 Aug 03; Vol. 83 (15), pp. 2753-2767.e10. Date of Electronic Publication: 2023 Jul 20.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 9802571 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4164 (Electronic) Linking ISSN: 10972765 NLM ISO Abbreviation: Mol Cell Subsets: MEDLINE

FALCON systematically interrogates free fatty acid biology and identifies a novel mediator of lipotoxicity.

Authors: Wieder N Fried JC Kim C et al.

Source: Cell metabolism [Cell Metab] 2023 May 02; Vol. 35 (5), pp. 887-905.e11. Date of Electronic Publication: 2023 Apr 18.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101233170 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1932-7420 (Electronic) Linking ISSN: 15504131 NLM ISO Abbreviation: Cell Metab Subsets: MEDLINE

P2RY2-AKT activation is a therapeutically actionable consequence of XPO1 inhibition in acute myeloid leukemia.

Authors: Lin KH Rutter JC Xie A et al.

Source: Nature cancer [Nat Cancer] 2022 Jul; Vol. 3 (7), pp. 837-851. Date of Electronic Publication: 2022 Jun 06.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101761119 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2662-1347 (Electronic) Linking ISSN: 26621347 NLM ISO Abbreviation: Nat Cancer Subsets: MEDLINE

Cancer cells depend on environmental lipids for proliferation when electron acceptors are limited.

Authors: Li Z Ji BW Dixit PD et al.

Source: Nature metabolism [Nat Metab] 2022 Jun; Vol. 4 (6), pp. 711-723. Date of Electronic Publication: 2022 Jun 23.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

Journal Info: Publisher: Springer Nature Country of Publication: Germany NLM ID: 101736592 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2522-5812 (Electronic) Linking ISSN: 25225812 NLM ISO Abbreviation: Nat Metab Subsets: MEDLINE

The Folate Cycle Enzyme MTHFR Is a Critical Regulator of Cell Response to MYC-Targeting Therapies.

Authors: Su A Ling F Vaganay C et al.

Source: Cancer discovery [Cancer Discov] 2020 Dec; Vol. 10 (12), pp. 1894-1911. Date of Electronic Publication: 2020 Aug 21.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 101561693 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2159-8290 (Electronic) Linking ISSN: 21598274 NLM ISO Abbreviation: Cancer Discov Subsets: MEDLINE

Using antagonistic pleiotropy to design a chemotherapy-induced evolutionary trap to target drug resistance in cancer.

Authors: Lin KH Rutter JC Xie A et al.

Source: Nature genetics [Nat Genet] 2020 Apr; Vol. 52 (4), pp. 408-417. Date of Electronic Publication: 2020 Mar 16.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

Journal Info: Publisher: Nature Pub. Co Country of Publication: United States NLM ID: 9216904 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-1718 (Electronic) Linking ISSN: 10614036 NLM ISO Abbreviation: Nat Genet Subsets: MEDLINE

Systematic Dissection of the Metabolic-Apoptotic Interface in AML Reveals Heme Biosynthesis to Be a Regulator of Drug Sensitivity.

Authors: Lin KH Xie A Rutter JC et al.

Source: Cell metabolism [Cell Metab] 2019 May 07; Vol. 29 (5), pp. 1217-1231.e7. Date of Electronic Publication: 2019 Feb 14.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101233170 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1932-7420 (Electronic) Linking ISSN: 15504131 NLM ISO Abbreviation: Cell Metab Subsets: MEDLINE