Search Results - "Samuel VT"

Targeting foxo1 in mice using antisense oligonucleotide improves hepatic and peripheral insulin action.

Authors: Samuel VT Choi CS Phillips TG et al.

Source: Diabetes. Jul2006, Vol. 55 Issue 7, p2042-2050. 9p.

URL: 21601357

SGLT2 deletion improves glucose homeostasis and preserves pancreatic beta-cell function.

Authors: Jurczak MJ Lee HY Birkenfeld AL et al.

Source: Diabetes. Mar2011, Vol. 60 Issue 3, p890-898. 9p.

Deletion of the alpha-arrestin protein Txnip in mice promotes adiposity and adipogenesis while preserving insulin sensitivity.

Authors: Chutkow WA Birkenfeld AL Brown JD et al.

Source: Diabetes. Jun2010, Vol. 59 Issue 6, p1424-1434. 11p.

CIDEB and CGI-58 differentially regulate liver lipid-droplet cholesterol to modulate metabolic dysfunction-associated steatohepatitis severity.

Authors: Sakuma I Gaspar RC Morgan HN et al.

Source: Cell reports [Cell Rep] 2026 Jun 23; Vol. 45 (6), pp. 117369. Date of Electronic Publication: 2026 Jun 03.

Publication Type: Journal Article

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE

Cideb knockdown in mice increases mitochondrial fat oxidation and reverses hepatic steatosis and insulin resistance by the plasma membrane sn-1,2-DAGs-PKCε-insulin receptor kinase^T1150 pathway.

Authors: Zheng J Gaspar RC Sakuma I et al.

Source: Diabetologia [Diabetologia] 2025 Dec; Vol. 68 (12), pp. 2906-2920. Date of Electronic Publication: 2025 Sep 04.

Publication Type: Journal Article

Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0006777 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0428 (Electronic) Linking ISSN: 0012186X NLM ISO Abbreviation: Diabetologia Subsets: MEDLINE

Liver lipid droplet cholesterol content is a key determinant of metabolic dysfunction-associated steatohepatitis.

Authors: Sakuma I Gaspar RC Nasiri AR et al.

Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2025 May 06; Vol. 122 (18), pp. e2502978122. Date of Electronic Publication: 2025 May 01.

Publication Type: Journal Article

Journal Info: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

Ceramide synthesis inhibitors prevent lipid-induced insulin resistance through the DAG-PKCε-insulin receptor^T1150 phosphorylation pathway.

Authors: Xu W Zhang D Ma Y et al.

Source: Cell reports [Cell Rep] 2024 Oct 22; Vol. 43 (10), pp. 114746. Date of Electronic Publication: 2024 Sep 19.

Publication Type: Journal Article; Research Support, N.I.H., Extramural

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE

High-fat-diet-induced hepatic insulin resistance per se attenuates murine de novo lipogenesis.

Authors: Goedeke L Strober JW Suh R et al.

Source: IScience [iScience] 2024 Oct 15; Vol. 27 (11), pp. 111175. Date of Electronic Publication: 2024 Oct 15 (Print Publication: 2024).

Publication Type: Journal Article

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101724038 Publication Model: eCollection Cited Medium: Internet ISSN: 2589-0042 (Electronic) Linking ISSN: 25890042 NLM ISO Abbreviation: iScience Subsets: PubMed not MEDLINE

Author Correction: Inhibition of Notch signaling ameliorates insulin resistance in a FoxO1-dependent manner.

Authors: Pajvani UB Shawber CJ Samuel VT et al.

Source: Nature medicine [Nat Med] 2024 Feb; Vol. 30 (2), pp. 604.

Publication Type: Published Erratum

Journal Info: Publisher: Nature Publishing Company Country of Publication: United States NLM ID: 9502015 Publication Model: Print Cited Medium: Internet ISSN: 1546-170X (Electronic) Linking ISSN: 10788956 NLM ISO Abbreviation: Nat Med Subsets: MEDLINE; PubMed not MEDLINE

Lysophosphatidic acid triggers inflammation in the liver and white adipose tissue in rat models of 1-acyl-sn-glycerol-3-phosphate acyltransferase 2 deficiency and overnutrition.

Authors: Sakuma I Gaspar RC Luukkonen PK et al.

Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2023 Dec 26; Vol. 120 (52), pp. e2312666120. Date of Electronic Publication: 2023 Dec 21.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

Adipose glucocorticoid action influences whole-body metabolism via modulation of hepatic insulin action.

Authors: Abulizi A Camporez JP Jurczak MJ et al.

Source: FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2019 Jul; Vol. 33 (7), pp. 8174-8185. Date of Electronic Publication: 2019 Mar 28.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.

Journal Info: Publisher: Federation of American Societies for Experimental Biology Country of Publication: United States NLM ID: 8804484 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1530-6860 (Electronic) Linking ISSN: 08926638 NLM ISO Abbreviation: FASEB J Subsets: MEDLINE

PEPCK1 Antisense Oligonucleotide Prevents Adiposity and Impairs Hepatic Glycogen Synthesis in High-Fat Male Fed Rats.

Authors: Beddow SA Gattu AK Vatner DF et al.

Source: Endocrinology [Endocrinology] 2019 Jan 01; Vol. 160 (1), pp. 205-219.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.

Journal Info: Publisher: Oxford University Press Country of Publication: United States NLM ID: 0375040 Publication Model: Print Cited Medium: Internet ISSN: 1945-7170 (Electronic) Linking ISSN: 00137227 NLM ISO Abbreviation: Endocrinology Subsets: MEDLINE

Deletion of Jazf1 gene causes early growth retardation and insulin resistance in mice.

Authors: Lee HY Jang HR Li H et al.

Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2022 Dec 06; Vol. 119 (49), pp. e2213628119. Date of Electronic Publication: 2022 Nov 28.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

Journal Info: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

Angptl8 antisense oligonucleotide improves adipose lipid metabolism and prevents diet-induced NAFLD and hepatic insulin resistance in rodents.

Authors: Vatner DF Goedeke L Camporez JG et al.

Source: Diabetologia [Diabetologia] 2018 Jun; Vol. 61 (6), pp. 1435-1446. Date of Electronic Publication: 2018 Mar 01.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.

Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0006777 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0428 (Electronic) Linking ISSN: 0012186X NLM ISO Abbreviation: Diabetologia Subsets: MEDLINE

Mitochondrial-Targeted Catalase Protects Against High-Fat Diet-Induced Muscle Insulin Resistance by Decreasing Intramuscular Lipid Accumulation.

Authors: Lee HY Lee JS Alves T et al.

Source: Diabetes [Diabetes] 2017 Aug; Vol. 66 (8), pp. 2072-2081. Date of Electronic Publication: 2017 May 05.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Diabetes Association Country of Publication: United States NLM ID: 0372763 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1939-327X (Electronic) Linking ISSN: 00121797 NLM ISO Abbreviation: Diabetes Subsets: MEDLINE

Insulin receptor Thr1160 phosphorylation mediates lipid-induced hepatic insulin resistance.

Authors: Petersen MC Madiraju AK Gassaway BM et al.

Source: The Journal of clinical investigation [J Clin Invest] 2016 Nov 01; Vol. 126 (11), pp. 4361-4371. Date of Electronic Publication: 2016 Oct 17.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1558-8238 (Electronic) Linking ISSN: 00219738 NLM ISO Abbreviation: J Clin Invest Subsets: MEDLINE

Second-generation antisense oligonucleotides against β-catenin protect mice against diet-induced hepatic steatosis and hepatic and peripheral insulin resistance.

Authors: Popov VB Jornayvaz FR Akgul EO et al.

Source: FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2016 Mar; Vol. 30 (3), pp. 1207-17. Date of Electronic Publication: 2015 Dec 07.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

Journal Info: Publisher: Federation of American Societies for Experimental Biology Country of Publication: United States NLM ID: 8804484 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1530-6860 (Electronic) Linking ISSN: 08926638 NLM ISO Abbreviation: FASEB J Subsets: MEDLINE

The pathogenesis of insulin resistance: integrating signaling pathways and substrate flux.

Authors: Samuel VT Shulman GI

Source: The Journal of clinical investigation [J Clin Invest] 2016 Jan; Vol. 126 (1), pp. 12-22. Date of Electronic Publication: 2016 Jan 04.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.; Review

Journal Info: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1558-8238 (Electronic) Linking ISSN: 00219738 NLM ISO Abbreviation: J Clin Invest Subsets: MEDLINE

3,5 Diiodo-L-Thyronine (T2) Does Not Prevent Hepatic Steatosis or Insulin Resistance in Fat-Fed Sprague Dawley Rats.

Authors: Vatner DF Snikeris J Popov V et al.

Source: PloS one [PLoS One] 2015 Oct 20; Vol. 10 (10), pp. e0140837. Date of Electronic Publication: 2015 Oct 20 (Print Publication: 2015).

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

Short-term overnutrition induces white adipose tissue insulin resistance through sn-1,2-diacylglycerol/PKCε/insulin receptor Thr1160 phosphorylation.

Authors: Lyu K Zhang D Song J et al.

Source: JCI insight [JCI Insight] 2021 Feb 22; Vol. 6 (4). Date of Electronic Publication: 2021 Feb 22.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.

Journal Info: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 101676073 Publication Model: Electronic Cited Medium: Internet ISSN: 2379-3708 (Electronic) Linking ISSN: 23793708 NLM ISO Abbreviation: JCI Insight Subsets: MEDLINE