Search Results - "Sandmann T"

Anti-CD22 and anti-CD79B antibody drug conjugates are active in different molecular diffuse large B-cell lymphoma subtypes.

Authors: Pfeifer, M Zheng, B Erdmann, T et al.

Source: Leukemia (08876924). Jul2015, Vol. 29 Issue 7, p1578-1586. 9p. 1 Color Photograph, 2 Charts, 2 Graphs.

55PDIdentification of biological axes associated with stage II/III CRC recurrence risk and outcome after adjuvant therapy revealed a T-effector-independent prognostic role for granzyme B.

Authors: Thakur, M Das Udyavar, A Sandmann, T et al.

Source: Annals of Oncology. 2018 Supplement, Vol. 29, pN.PAG-N.PAG. 1p.

Author Correction: Fc-engineered large molecules targeting blood-brain barrier transferrin receptor and CD98hc have distinct central nervous system and peripheral biodistribution.

Authors: Khoury N Pizzo ME Discenza CB et al.

Source: Nature communications [Nat Commun] 2026 Apr 15; Vol. 17 (1). Date of Electronic Publication: 2026 Apr 15.

Publication Type: Published Erratum

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE; In Process

Microglial TDP-43 mediates myelin refinement and represses Tyrobp cryptic exon inclusion in mice.

Authors: Compagnion AC Ivanov A Rana A et al.

Source: Nature neuroscience [Nat Neurosci] 2026 Jul 08. Date of Electronic Publication: 2026 Jul 08.

Publication Type: Journal Article

Journal Info: Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 9809671 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-1726 (Electronic) Linking ISSN: 10976256 NLM ISO Abbreviation: Nat Neurosci Subsets: MEDLINE

Towards an AI biomedical scientist: Accelerating discoveries in neurodegenerative disease.

Authors: Roberts KF Landsness EC Reese J et al.

Source: The journal of prevention of Alzheimer's disease [J Prev Alzheimers Dis] 2025 Dec 01, pp. 100398. Date of Electronic Publication: 2025 Dec 01.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 101638820 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2426-0266 (Electronic) Linking ISSN: 22745807 NLM ISO Abbreviation: J Prev Alzheimers Dis Subsets: MEDLINE

DNL343 is an investigational CNS penetrant eukaryotic initiation factor 2B activator that prevents and reverses the effects of neurodegeneration caused by the integrated stress response.

Authors: Yulyaningsih E Suh JH Fanok M et al.

Source: ELife [Elife] 2024 Sep 17; Vol. 12. Date of Electronic Publication: 2024 Sep 17.

Publication Type: Journal Article

Journal Info: Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic Cited Medium: Internet ISSN: 2050-084X (Electronic) Linking ISSN: 2050084X NLM ISO Abbreviation: Elife Subsets: MEDLINE

Targeting the transferrin receptor to transport antisense oligonucleotides across the mammalian blood-brain barrier.

Authors: Barker SJ Thayer MB Kim C et al.

Source: Science translational medicine [Sci Transl Med] 2024 Aug 14; Vol. 16 (760), pp. eadi2245. Date of Electronic Publication: 2024 Aug 14.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE

Peripheral expression of brain-penetrant progranulin rescues pathologies in mouse models of frontotemporal lobar degeneration.

Authors: Reich M Simon MJ Polke B et al.

Source: Science translational medicine [Sci Transl Med] 2024 Jun 05; Vol. 16 (750), pp. eadj7308. Date of Electronic Publication: 2024 Jun 05.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE

Early intervention anti-Aβ immunotherapy attenuates microglial activation without inducing exhaustion at residual plaques.

Authors: de Weerd L Hummel S Müller SA et al.

Source: Molecular neurodegeneration [Mol Neurodegener] 2025 Aug 20; Vol. 20 (1), pp. 92. Date of Electronic Publication: 2025 Aug 20.

Publication Type: Journal Article

Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101266600 Publication Model: Electronic Cited Medium: Internet ISSN: 1750-1326 (Electronic) Linking ISSN: 17501326 NLM ISO Abbreviation: Mol Neurodegener Subsets: MEDLINE

Investigational eIF2B activator DNL343 modulates the integrated stress response in preclinical models of TDP-43 pathology and individuals with ALS in a randomized clinical trial.

Authors: Flores BN Yu SB Cohen IV et al.

Source: Nature communications [Nat Commun] 2025 Aug 18; Vol. 16 (1), pp. 7690. Date of Electronic Publication: 2025 Aug 18.

Publication Type: Journal Article; Randomized Controlled Trial; Clinical Trial, Phase I

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

The Genetic Drivers of Juvenile, Young, and Early-Onset Parkinson's Disease in India.

Authors: Andrews SV Kukkle PL Menon R et al.

Corporate Authors: Andrews SV Kukkle PL Menon R et al.

Source: Movement disorders : official journal of the Movement Disorder Society [Mov Disord] 2024 Feb; Vol. 39 (2), pp. 339-349. Date of Electronic Publication: 2023 Nov 28.

Publication Type: Journal Article

Journal Info: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 8610688 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1531-8257 (Electronic) Linking ISSN: 08853185 NLM ISO Abbreviation: Mov Disord Subsets: MEDLINE

Fc-engineered large molecules targeting blood-brain barrier transferrin receptor and CD98hc have distinct central nervous system and peripheral biodistribution.

Authors: Khoury N Pizzo ME Discenza CB et al.

Source: Nature communications [Nat Commun] 2025 Feb 20; Vol. 16 (1), pp. 1822. Date of Electronic Publication: 2025 Feb 20.

Publication Type: Journal Article

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

Decreased lipidated ApoE-receptor interactions confer protection against pathogenicity of ApoE and its lipid cargoes in lysosomes.

Authors: Guo JL Braun D Fitzgerald GA et al.

Source: Cell [Cell] 2025 Jan 09; Vol. 188 (1), pp. 187-206.e26. Date of Electronic Publication: 2024 Nov 11.

Publication Type: Journal Article

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 0413066 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4172 (Electronic) Linking ISSN: 00928674 NLM ISO Abbreviation: Cell Subsets: MEDLINE

Transcriptomic profiling of adjuvant colorectal cancer identifies three key prognostic biological processes and a disease specific role for granzyme B.

Authors: Daemen A Udyavar AR Sandmann T et al.

Source: PloS one [PLoS One] 2021 Dec 31; Vol. 16 (12), pp. e0262198. Date of Electronic Publication: 2021 Dec 31 (Print Publication: 2021).

Publication Type: Clinical Trial, Phase III; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

Brain delivery and activity of a lysosomal enzyme using a blood-brain barrier transport vehicle in mice.

Authors: Ullman JC Arguello A Getz JA et al.

Source: Science translational medicine [Sci Transl Med] 2020 May 27; Vol. 12 (545).

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE

Obinutuzumab plus CHOP is effective and has a tolerable safety profile in previously untreated, advanced diffuse large B-cell lymphoma: the phase II GATHER study.

Authors: Sharman JP Forero-Torres A Costa LJ et al.

Source: Leukemia & lymphoma [Leuk Lymphoma] 2019 Apr; Vol. 60 (4), pp. 894-903. Date of Electronic Publication: 2018 Oct 02.

Publication Type: Clinical Trial, Phase II; Journal Article; Multicenter Study; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 9007422 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1029-2403 (Electronic) Linking ISSN: 10268022 NLM ISO Abbreviation: Leuk Lymphoma Subsets: MEDLINE

Radiologic progression of glioblastoma under therapy-an exploratory analysis of AVAglio.

Authors: Nowosielski M Ellingson BM Chinot OL et al.

Source: Neuro-oncology [Neuro Oncol] 2018 Mar 27; Vol. 20 (4), pp. 557-566.

Publication Type: Clinical Trial, Phase III; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 100887420 Publication Model: Print Cited Medium: Internet ISSN: 1523-5866 (Electronic) Linking ISSN: 15228517 NLM ISO Abbreviation: Neuro Oncol Subsets: MEDLINE

Novel App knock-in mouse model shows key features of amyloid pathology and reveals profound metabolic dysregulation of microglia.

Authors: Xia D Lianoglou S Sandmann T et al.

Source: Molecular neurodegeneration [Mol Neurodegener] 2022 Jun 11; Vol. 17 (1), pp. 41. Date of Electronic Publication: 2022 Jun 11.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101266600 Publication Model: Electronic Cited Medium: Internet ISSN: 1750-1326 (Electronic) Linking ISSN: 17501326 NLM ISO Abbreviation: Mol Neurodegener Subsets: MEDLINE

Alzheimer's-associated PLCγ2 is a signaling node required for both TREM2 function and the inflammatory response in human microglia.

Authors: Andreone BJ Przybyla L Llapashtica C et al.

Source: Nature neuroscience [Nat Neurosci] 2020 Aug; Vol. 23 (8), pp. 927-938. Date of Electronic Publication: 2020 Jun 08.

Publication Type: Journal Article

Journal Info: Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 9809671 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-1726 (Electronic) Linking ISSN: 10976256 NLM ISO Abbreviation: Nat Neurosci Subsets: MEDLINE

Embryo development. A cysteine-clamp gene drives embryo polarity in the midge Chironomus.

Authors: Klomp J Athy D Kwan CW et al.

Source: Science (New York, N.Y.) [Science] 2015 May 29; Vol. 348 (6238), pp. 1040-2. Date of Electronic Publication: 2015 May 07.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE