Search Results - "Sheehy, Adam"

Viral-mediated knockdown of Atxn2 attenuates TDP-43 pathology and muscle dysfunction in the PFN1^C71G ALS mouse model.

Authors: Hawley, Zachary C. E. Li, Xueying Bodnar, Dora et al.

Source: Acta Neuropathologica Communications. 5/24/2025, Vol. 13 Issue 1, p1-22. 22p.

Dimethyl fumarate alters microglia phenotype and protects neurons against proinflammatory toxic microenvironments.

Authors: Peng, Haiyan Li, Huo Sheehy, Adam et al.

Source: Journal of Neuroimmunology. Oct2016, Vol. 299, p35-44. 10p.

The JAK2 Inhibitor AZD1480 Potently Blocks Stat3 Signaling and Oncogenesis in Solid Tumors

Authors: Hedvat, Michael Huszar, Dennis Herrmann, Andreas et al.

Source: Cancer Cell. Dec2009, Vol. 16 Issue 6, p487-497. 11p.

Identification of a therapeutic threshold for AAV-STXBP1 gene therapy in a rodent model of STXBP1 developmental and epileptic encephalopathy.

Authors: Gallo NB Annand JW Clarner P et al.

Source: Molecular therapy : the journal of the American Society of Gene Therapy [Mol Ther] 2026 Jul 01; Vol. 34 (7), pp. 3763-3782. Date of Electronic Publication: 2026 Mar 24.

Publication Type: Journal Article

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 100890581 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1525-0024 (Electronic) Linking ISSN: 15250016 NLM ISO Abbreviation: Mol Ther Subsets: MEDLINE

In vivo genome editing using novel AAV-PHP variants rescues motor function deficits and extends survival in a SOD1-ALS mouse model.

Authors: Chen YA Kankel MW Hana S et al.

Source: Gene therapy [Gene Ther] 2023 May; Vol. 30 (5), pp. 443-454. Date of Electronic Publication: 2022 Dec 01.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 9421525 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5462 (Electronic) Linking ISSN: 09697128 NLM ISO Abbreviation: Gene Ther Subsets: MEDLINE

AZD7762, a novel checkpoint kinase inhibitor, drives checkpoint abrogation and potentiates DNA-targeted therapies.

Authors: Zabludoff SD Deng C Grondine MR et al.

Source: Molecular cancer therapeutics [Mol Cancer Ther] 2008 Sep; Vol. 7 (9), pp. 2955-66.

Publication Type: Journal Article

Journal Info: Publisher: American Association for Cancer Research, Inc Country of Publication: United States NLM ID: 101132535 Publication Model: Print Cited Medium: Print ISSN: 1535-7163 (Print) Linking ISSN: 15357163 NLM ISO Abbreviation: Mol Cancer Ther Subsets: MEDLINE