Search Results - "Shepard HM"

Reactivating p53 mutants selectively in patients.

Authors: Chen S Shepard HM Lu M

Source: Cancer cell [Cancer Cell] 2026 Apr 13; Vol. 44 (4), pp. 715-717. Date of Electronic Publication: 2026 Apr 02.

Publication Type: Journal Article

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101130617 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-3686 (Electronic) Linking ISSN: 15356108 NLM ISO Abbreviation: Cancer Cell Subsets: MEDLINE

Targeting deoxycytidine kinase improves symptoms in mouse models of multiple sclerosis.

Authors: Chen BY Salas JR Trias AO et al.

Source: Immunology [Immunology] 2023 Jan; Vol. 168 (1), pp. 152-169. Date of Electronic Publication: 2022 Sep 04.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

Journal Info: Publisher: Blackwell Scientific Publications Country of Publication: England NLM ID: 0374672 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2567 (Electronic) Linking ISSN: 00192805 NLM ISO Abbreviation: Immunology Subsets: MEDLINE

Trastuzumab: dreams, desperation and hope.

Authors: Shepard HM; Enosi Therapeutics, Knight Campus Innovation Center, Eugene, OR, USA. mike.shepard@enositherapeutics.com.

Source: Nature reviews. Cancer [Nat Rev Cancer] 2024 May; Vol. 24 (5), pp. 287-288.

Publication Type: Journal Article

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101124168 Publication Model: Print Cited Medium: Internet ISSN: 1474-1768 (Electronic) Linking ISSN: 1474175X NLM ISO Abbreviation: Nat Rev Cancer Subsets: MEDLINE

Biomarker-Driven Drug Discovery in Cancer-Trastuzumab Development: 2019 Lasker-DeBakey Clinical Medical Research Award.

Authors: Shepard HM; Biooncology Consultants, San Diego, California.

Source: JAMA [JAMA] 2019 Oct 01; Vol. 322 (13), pp. 1249-1250.

Publication Type: Journal Article

Journal Info: Publisher: American Medical Association Country of Publication: United States NLM ID: 7501160 Publication Model: Print Cited Medium: Internet ISSN: 1538-3598 (Electronic) Linking ISSN: 00987484 NLM ISO Abbreviation: JAMA Subsets: MEDLINE; PubMed not MEDLINE

KIAA1199 expression and hyaluronan degradation colocalize in multiple sclerosis lesions.

Authors: Marella M Jadin L Keller GA et al.

Source: Glycobiology [Glycobiology] 2018 Dec 01; Vol. 28 (12), pp. 958-967.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: IRL Press at Oxford University Press Country of Publication: England NLM ID: 9104124 Publication Model: Print Cited Medium: Internet ISSN: 1460-2423 (Electronic) Linking ISSN: 09596658 NLM ISO Abbreviation: Glycobiology Subsets: MEDLINE

Targeting Adenosine with Adenosine Deaminase 2 to Inhibit Growth of Solid Tumors.

Authors: Wang L Londono LM Cowell J et al.

Source: Cancer research [Cancer Res] 2021 Jun 15; Vol. 81 (12), pp. 3319-3332. Date of Electronic Publication: 2021 Apr 16.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 2984705R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-7445 (Electronic) Linking ISSN: 00085472 NLM ISO Abbreviation: Cancer Res Subsets: MEDLINE

Breaching the Castle Walls: Hyaluronan Depletion as a Therapeutic Approach to Cancer Therapy.

Authors: Shepard HM; Halozyme Therapeutics Inc. , San Diego, CA , USA.

Source: Frontiers in oncology [Front Oncol] 2015 Aug 28; Vol. 5, pp. 192. Date of Electronic Publication: 2015 Aug 28 (Print Publication: 2015).

Publication Type: Journal Article; Review

Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101568867 Publication Model: eCollection Cited Medium: Print ISSN: 2234-943X (Print) Linking ISSN: 2234943X NLM ISO Abbreviation: Front Oncol Subsets: PubMed not MEDLINE

Human epidermal growth factor receptor bispecific ligand trap RB200: abrogation of collagen-induced arthritis in combination with tumour necrosis factor blockade.

Authors: Gompels LL Malik NM Madden L et al.

Source: Arthritis research & therapy [Arthritis Res Ther] 2011; Vol. 13 (5), pp. R161. Date of Electronic Publication: 2011 Oct 07.

Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101154438 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1478-6362 (Electronic) Linking ISSN: 14786354 NLM ISO Abbreviation: Arthritis Res Ther Subsets: MEDLINE

Multiple cancer-specific antigens are targeted by a chimeric antigen receptor on a single cancer cell.

Authors: He Y Schreiber K Wolf SP et al.

Source: JCI insight [JCI Insight] 2019 Dec 05; Vol. 4 (23). Date of Electronic Publication: 2019 Dec 05.

Publication Type: Journal Article; Published Erratum

Journal Info: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 101676073 Publication Model: Electronic Cited Medium: Internet ISSN: 2379-3708 (Electronic) Linking ISSN: 23793708 NLM ISO Abbreviation: JCI Insight Subsets: MEDLINE; PubMed not MEDLINE

The growth of a xenograft breast cancer tumor model with engineered hyaluronan-accumulating stroma is dependent on hyaluronan and independent of CD44.

Authors: Zhao C Thompson BJ Chen K et al.

Source: Oncotarget [Oncotarget] 2019 Nov 12; Vol. 10 (61), pp. 6561-6576. Date of Electronic Publication: 2019 Nov 12 (Print Publication: 2019).

Publication Type: Journal Article

Journal Info: Publisher: Impact Journals Country of Publication: United States NLM ID: 101532965 Publication Model: eCollection Cited Medium: Internet ISSN: 1949-2553 (Electronic) Linking ISSN: 19492553 NLM ISO Abbreviation: Oncotarget Subsets: PubMed not MEDLINE

Multiple cancer-specific antigens are targeted by a chimeric antigen receptor on a single cancer cell.

Authors: He Y Schreiber K Wolf SP et al.

Source: JCI insight [JCI Insight] 2019 Nov 01; Vol. 4 (21). Date of Electronic Publication: 2019 Nov 01.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 101676073 Publication Model: Electronic Cited Medium: Internet ISSN: 2379-3708 (Electronic) Linking ISSN: 23793708 NLM ISO Abbreviation: JCI Insight Subsets: MEDLINE

The Team that Just Wouldn't Quit and a New Paradigm in Cancer Drug Discovery.

Authors: Shepard HM; Biooncology Consultants, San Diego, CA, USA. Electronic address: hms@biologics21.net.

Source: Cell [Cell] 2019 Sep 19; Vol. 179 (1), pp. 27-32. Date of Electronic Publication: 2019 Sep 10.

Publication Type: Journal Article

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 0413066 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4172 (Electronic) Linking ISSN: 00928674 NLM ISO Abbreviation: Cell Subsets: MEDLINE; PubMed not MEDLINE

Rational optimization of a bispecific ligand trap targeting EGF receptor family ligands.

Authors: Jin P Zhang J Beryt M et al.

Source: Molecular medicine (Cambridge, Mass.) [Mol Med] 2009 Jan-Feb; Vol. 15 (1-2), pp. 11-20. Date of Electronic Publication: 2008 Nov 17.

Publication Type: Journal Article

Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 9501023 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1528-3658 (Electronic) Linking ISSN: 10761551 NLM ISO Abbreviation: Mol Med Subsets: MEDLINE

Signal integration: a framework for understanding the efficacy of therapeutics targeting the human EGFR family.

Authors: Shepard HM Brdlik CM Schreiber H

Source: The Journal of clinical investigation [J Clin Invest] 2008 Nov; Vol. 118 (11), pp. 3574-81.

Publication Type: Journal Article; Review

Journal Info: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model: Print Cited Medium: Print ISSN: 0021-9738 (Print) Linking ISSN: 00219738 NLM ISO Abbreviation: J Clin Invest Subsets: MEDLINE

Parallel Accumulation of Tumor Hyaluronan, Collagen, and Other Drivers of Tumor Progression.

Authors: Li X Shepard HM Cowell JA et al.

Source: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2018 Oct 01; Vol. 24 (19), pp. 4798-4807. Date of Electronic Publication: 2018 Jul 03.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 9502500 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1557-3265 (Electronic) Linking ISSN: 10780432 NLM ISO Abbreviation: Clin Cancer Res Subsets: MEDLINE

Enhancement of adenovirus-mediated gene transfer to human bone marrow cells.

Authors: Watanabe T Kelsey L Ageitos A et al.

Source: Leukemia & lymphoma [Leuk Lymphoma] 1998 May; Vol. 29 (5-6), pp. 439-51.

Publication Type: Journal Article

Journal Info: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 9007422 Publication Model: Print Cited Medium: Print ISSN: 1042-8194 (Print) Linking ISSN: 10268022 NLM ISO Abbreviation: Leuk Lymphoma Subsets: MEDLINE

p53-mediated accumulation of hypophosphorylated pRb after the G1 restriction point fails to halt cell cycle progression.

Authors: Linke SP Harris MP Neugebauer SE et al.

Source: Oncogene [Oncogene] 1997 Jul 17; Vol. 15 (3), pp. 337-45.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print Cited Medium: Print ISSN: 0950-9232 (Print) Linking ISSN: 09509232 NLM ISO Abbreviation: Oncogene Subsets: MEDLINE

Phase 1 trials of PEGylated recombinant human hyaluronidase PH20 in patients with advanced solid tumours.

Authors: Infante JR Korn RL Rosen LS et al.

Source: British journal of cancer [Br J Cancer] 2018 Jan; Vol. 118 (2), pp. 153-161. Date of Electronic Publication: 2017 Sep 26.

Publication Type: Clinical Trial, Phase I; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Nature Publishing Group on behalf of Cancer Research UK Country of Publication: England NLM ID: 0370635 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-1827 (Electronic) Linking ISSN: 00070920 NLM ISO Abbreviation: Br J Cancer Subsets: MEDLINE

Phase 1 trials of PEGylated recombinant human hyaluronidase PH20 in patients with advanced solid tumours.

Authors: Infante JR Korn RL Rosen LS et al.

Source: British journal of cancer [Br J Cancer] 2018 Jan; Vol. 118 (2), pp. e3.

Publication Type: Journal Article; Published Erratum

Journal Info: Publisher: Nature Publishing Group on behalf of Cancer Research UK Country of Publication: England NLM ID: 0370635 Publication Model: Print Cited Medium: Internet ISSN: 1532-1827 (Electronic) Linking ISSN: 00070920 NLM ISO Abbreviation: Br J Cancer Subsets: PubMed not MEDLINE

Developments in therapy with monoclonal antibodies and related proteins.

Authors: Shepard HM Phillips GL D Thanos C et al.

Source: Clinical medicine (London, England) [Clin Med (Lond)] 2017 Jun; Vol. 17 (3), pp. 220-232.

Publication Type: Journal Article; Review

Journal Info: Publisher: Elsevier Ltd Country of Publication: England NLM ID: 101092853 Publication Model: Print Cited Medium: Internet ISSN: 1473-4893 (Electronic) Linking ISSN: 14702118 NLM ISO Abbreviation: Clin Med (Lond) Subsets: MEDLINE