Search Results - "Shepard RL"

The key enzyme PYCR1 in proline metabolism: a dual driver of cancer progression and fibrotic remodeling.

Authors: Guo, Peng Wu, Chenchun Wang, Tong et al.

Source: Journal of Enzyme Inhibition & Medicinal Chemistry. Dec2025, Vol. 40 Issue 1, p1-21. 21p.

Anticancer drug response prediction integrating multi-omics pathway-based difference features and multiple deep learning techniques.

Authors: Wu, Yang Chen, Ming Qin, Yufang

Source: PLoS Computational Biology. 3/31/2025, Vol. 21 Issue 3, p1-33. 33p.

Hypoxia-Inducible Factor 1-alpha (HIF1α), Nicotinamide Adenine Dinucleotide (NAD+, NADH), and Nitric Oxide (NO) interplay in critically ill patients, with implications for patient safety and targeted therapies: a review.

Authors: Bar-Or, David Banton, Kaysie Acuna, David et al.

Source: Patient Safety in Surgery. 10/27/2025, Vol. 19 Issue 1, p1-12. 12p.

Trauma-Related Stress and Resilience in a Multistate Sample of Methadone Treatment Staff.

Authors: Coffee, Zhanette Linde-Krieger, Linnea Carter, Gregory A. et al.

Source: Substance Use: Research & Treatment. 10/15/2025, Vol. 19, p1-14. 14p.

The significance of DNA methylation of the NR3C1 gene encoding the glucocorticoid receptor for developing resilience in individuals exposed to early life stress.

Authors: Forum, Ditte Mathilde Klith Bjerregaard, Camilla Thomsen, Per Hove

Source: Nordic Journal of Psychiatry. Jan2025, Vol. 79 Issue 1, p1-14. 14p.

Subjects: Psychological resilience, Psychiatric diagnosis, Glucocorticoid receptors, DNA methylation

Efficacy of NAMPT inhibition in T-cell acute lymphoblastic leukemia.

Authors: Vrana, Chelsea Zhang, Matthew Rochette, Max et al.

Source: PLoS ONE. 6/17/2025, Vol. 20 Issue 6, p1-12. 12p.

The effects of low-dose X-ray pre-irradiation followed by 4-hydroxybenzoic acid and vanillic acid on P-glycoprotein-mediated efflux pirarubicin in multidrug-resistant K562/Dox cells.

Authors: Myint O Supawat B Kothan S et al.

Source: Naunyn-Schmiedeberg's archives of pharmacology [Naunyn Schmiedebergs Arch Pharmacol] 2026 May; Vol. 399 (8), pp. 12037-12055. Date of Electronic Publication: 2026 Mar 03.

Publication Type: Journal Article

Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0326264 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1912 (Electronic) Linking ISSN: 00281298 NLM ISO Abbreviation: Naunyn Schmiedebergs Arch Pharmacol Subsets: MEDLINE

Regulation of autophagy by the p53 family and the implications for cancer therapies.

Authors: Hsin IL Chen CC Sung YT et al.

Source: Discover oncology [Discov Oncol] 2026 May 12; Vol. 17 (1). Date of Electronic Publication: 2026 May 12.

Publication Type: Journal Article; Review

Journal Info: Publisher: Springer Country of Publication: United States NLM ID: 101775142 Publication Model: Electronic Cited Medium: Internet ISSN: 2730-6011 (Electronic) Linking ISSN: 27306011 NLM ISO Abbreviation: Discov Oncol Subsets: PubMed not MEDLINE

Question answering over knowledge graphs using BERT based relation mapping.

Authors: C. M., Suneera Prakash, Jay Singh, Pramod Kumar

Source: Expert Systems; Dec2023, Vol. 40 Issue 10, p1-17, 17p

Heteroaryl derivatives of suvorexant as OX1R selective PET ligand candidates: Cu-mediated ¹⁸F-fluorination of boroxines, in vitro and initial in vivo evaluation.

Authors: Bolik, Kim-Viktoria Hellmann, Jan Maschauer, Simone et al.

Source: EJNMMI Research. 9/4/2024, Vol. 14 Issue 1, p1-16. 16p.

Revisiting strategies to target ABC transporter-mediated drug resistance in CNS cancer.

Authors: Amawi, Haneen Hammad, Alaa M. Hall, F. Scott et al.

Source: Cancer Biology & Medicine. Oct2025, Vol. 22 Issue 10, p1158-1180. 23p.

Pharmacological strategies to enhance the response of hepatoblastoma to chemotherapy through MDR1 inhibition.

Authors: Cives-Losada C Macias RIR Lozano E et al.

Source: Acta pharmacologica Sinica [Acta Pharmacol Sin] 2026 Aug; Vol. 47 (8), pp. 2254-2267. Date of Electronic Publication: 2026 Apr 23.

Publication Type: Journal Article

Journal Info: Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 100956087 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1745-7254 (Electronic) Linking ISSN: 16714083 NLM ISO Abbreviation: Acta Pharmacol Sin Subsets: MEDLINE

Gender differences in the association between childhood trauma, clinical symptoms, and cognitive function in Chinese patients with chronic schizophrenia.

Authors: Shang, ZhaoXuan Fang, ChunQing Luo, GuoShuai et al.

Source: Social Psychiatry & Psychiatric Epidemiology. Aug2025, Vol. 60 Issue 8, p1999-2012. 14p.

Subjects: Gender differences (Sociology), Adverse childhood experiences, Chinese people, Statistical correlation, Cognitive ability, Therapeutics, Symptoms, Schizophrenia

Association between childhood physical abuse and gastrointestinal disorders and migraine in adulthood.

Authors: Goodwin RD Hoven CW Murison R et al.

Source: American Journal of Public Health. Jul2003, Vol. 93 Issue 7, p1065-1067. 3p.

URL: 10164655

Navigating liver cancer: Precision targeting for enhanced treatment outcomes.

Authors: Jain A Mishra AK Hurkat P et al.

Source: Drug delivery and translational research [Drug Deliv Transl Res] 2025 Jun; Vol. 15 (6), pp. 1935-1961. Date of Electronic Publication: 2025 Jan 23.

Publication Type: Journal Article; Review

Journal Info: Publisher: Springer Country of Publication: United States NLM ID: 101540061 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2190-3948 (Electronic) Linking ISSN: 2190393X NLM ISO Abbreviation: Drug Deliv Transl Res Subsets: MEDLINE

THP-1-derived polarized macrophages differ by drug transporter transcriptomics, P-glycoprotein activity and rifampicin uptake kinetics.

Authors: Hamburg K Bay C Burhenne J et al.

Source: Archives of toxicology [Arch Toxicol] 2026 Apr; Vol. 100 (4), pp. 1377-1389. Date of Electronic Publication: 2026 Jan 09.

Publication Type: Journal Article

Journal Info: Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 0417615 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0738 (Electronic) Linking ISSN: 03405761 NLM ISO Abbreviation: Arch Toxicol Subsets: MEDLINE

Intense endoplasmic reticulum stress (ERS) / IRE1α enhanced Oxaliplatin efficacy by decreased ABCC10 in colorectal cancer cells.

Authors: Liu, Xiaohui Wu, Bo Chen, Hong et al.

Source: BMC Cancer. 12/30/2022, Vol. 22 Issue 1, p1-16. 16p.

Inhibition of the NAD salvage pathway in schistosomes impairs metabolism, reproduction, and parasite survival.

Authors: Schultz, Michael D. Dadali, Tulin Jacques, Sylvain A. et al.

Source: PLoS Pathogens. 5/27/2020, Vol. 16 Issue 5, p1-32. 32p.

Prediction of P-glycoprotein inhibitors with machine learning classification models and 3D-RISM-KH theory based solvation energy descriptors.

Authors: Hinge, Vijaya Kumar Roy, Dipankar Kovalenko, Andriy

Source: Journal of Computer-Aided Molecular Design; Nov2019, Vol. 33 Issue 11, p965-971, 7p

Alternative splicing in ovarian cancer.

Authors: Wei, Liwei Li, Yisheng Chen, Jiawang et al.

Source: Cell Communication & Signaling. 10/18/2024, Vol. 22 Issue 1, p1-20. 20p.