Search Results - "Simmonds RE"

Assessing the acceptability of photographs and medical illustrations in Buruli ulcer health communication among health providers, community volunteers and community members in endemic districts of Ghana.

Authors: Tuwor RD Butler J Tetteh S et al.

Source: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2026 Apr 22; Vol. 20 (4), pp. e0014275. Date of Electronic Publication: 2026 Apr 22 (Print Publication: 2026).

Publication Type: Journal Article

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101291488 Publication Model: eCollection Cited Medium: Internet ISSN: 1935-2735 (Electronic) Linking ISSN: 19352727 NLM ISO Abbreviation: PLoS Negl Trop Dis Subsets: MEDLINE

A mycobacterial Sec61 inhibitor disrupts lysosome function by blocking Vacuolar-ATPase biosynthesis.

Authors: Hall BS Owusu-Boateng K McPhail KL et al.

Source: European journal of cell biology [Eur J Cell Biol] 2026 Apr 21; Vol. 105 (3), pp. 151541. Date of Electronic Publication: 2026 Apr 21.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: Germany NLM ID: 7906240 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1618-1298 (Electronic) Linking ISSN: 01719335 NLM ISO Abbreviation: Eur J Cell Biol Subsets: MEDLINE

Micronutrient-deficient diets and possible environmental enteric dysfunction in Buruli ulcer endemic communities in Ghana: Lower dietary diversity and reduced serum zinc and vitamin C implicate micronutrient status a possible susceptibility factor.

Authors: Loglo AD Antwi PB Abass KM et al.

Source: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2025 Mar 12; Vol. 19 (3), pp. e0012871. Date of Electronic Publication: 2025 Mar 12 (Print Publication: 2025).

Publication Type: Journal Article

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101291488 Publication Model: eCollection Cited Medium: Internet ISSN: 1935-2735 (Electronic) Linking ISSN: 19352727 NLM ISO Abbreviation: PLoS Negl Trop Dis Subsets: MEDLINE

The Mycobacterium ulcerans toxin mycolactone causes destructive Sec61-dependent loss of the endothelial glycocalyx and vessel basement membrane to drive skin necrosis.

Authors: Hsieh LT Hall BS Newcombe J et al.

Source: ELife [Elife] 2025 Feb 06; Vol. 12. Date of Electronic Publication: 2025 Feb 06.

Publication Type: Journal Article

Journal Info: Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic Cited Medium: Internet ISSN: 2050-084X (Electronic) Linking ISSN: 2050084X NLM ISO Abbreviation: Elife Subsets: MEDLINE

Buruli ulcer.

Authors: Yotsu RR Simmonds RE de Souza DK et al.

Source: Nature reviews. Disease primers [Nat Rev Dis Primers] 2025 Dec 18; Vol. 11 (1), pp. 89. Date of Electronic Publication: 2025 Dec 18.

Publication Type: Journal Article; Review

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101672103 Publication Model: Electronic Cited Medium: Internet ISSN: 2056-676X (Electronic) Linking ISSN: 2056676X NLM ISO Abbreviation: Nat Rev Dis Primers Subsets: MEDLINE

Multisensory medical illustrations of Buruli ulcer for improved disease detection, help seeking behaviour and adherence to treatment.

Authors: Butler J Ogden J Phillips R et al.

Source: Journal of visual communication in medicine [J Vis Commun Med] 2024 Jan; Vol. 47 (1), pp. 8-20. Date of Electronic Publication: 2024 May 21.

Publication Type: Journal Article

Journal Info: Publisher: Informa Healthcare Country of Publication: England NLM ID: 101254059 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1745-3062 (Electronic) Linking ISSN: 17453054 NLM ISO Abbreviation: J Vis Commun Med Subsets: MEDLINE

Editorial: Host-pathogen interactions in nontuberculous mycobacterial infections.

Authors: Lorè NI Yamasaki S Simmonds RE et al.

Source: Frontiers in immunology [Front Immunol] 2023 May 26; Vol. 14, pp. 1201159. Date of Electronic Publication: 2023 May 26 (Print Publication: 2023).

Publication Type: Editorial

Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE; PubMed not MEDLINE

A systematic review and meta-analysis of the association between neglected tropical diseases and malnutrition: more research needed on diseases other than intestinal parasites, leishmaniasis and leprosy.

Authors: Loglo A Aniagyei W Vivekanandan MM et al.

Source: Access microbiology [Access Microbiol] 2024 Nov 13; Vol. 6 (11). Date of Electronic Publication: 2024 Nov 13 (Print Publication: 2024).

Publication Type: Journal Article

Journal Info: Publisher: Microbiology Society Country of Publication: England NLM ID: 101746927 Publication Model: eCollection Cited Medium: Internet ISSN: 2516-8290 (Electronic) Linking ISSN: 25168290 NLM ISO Abbreviation: Access Microbiol Subsets: PubMed not MEDLINE

Synthesis, Biological Evaluation and Docking Studies of Ring-Opened Analogues of Ipomoeassin F.

Authors: O'Keefe S Bhadra P Duah KB et al.

Source: Molecules (Basel, Switzerland) [Molecules] 2022 Jul 10; Vol. 27 (14). Date of Electronic Publication: 2022 Jul 10.

Publication Type: Journal Article

Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049 (Electronic) Linking ISSN: 14203049 NLM ISO Abbreviation: Molecules Subsets: MEDLINE

Inhibition of the SEC61 translocon by mycolactone induces a protective autophagic response controlled by EIF2S1-dependent translation that does not require ULK1 activity.

Authors: Hall BS Dos Santos SJ Hsieh LT et al.

Source: Autophagy [Autophagy] 2022 Apr; Vol. 18 (4), pp. 841-859. Date of Electronic Publication: 2021 Aug 23.

Publication Type: Journal Article

Journal Info: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101265188 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1554-8635 (Electronic) Linking ISSN: 15548627 NLM ISO Abbreviation: Autophagy Subsets: MEDLINE

Aberrant stromal tissue factor localisation and mycolactone-driven vascular dysfunction, exacerbated by IL-1β, are linked to fibrin formation in Buruli ulcer lesions.

Authors: Hsieh LT Dos Santos SJ Hall BS et al.

Source: PLoS pathogens [PLoS Pathog] 2022 Jan 31; Vol. 18 (1), pp. e1010280. Date of Electronic Publication: 2022 Jan 31 (Print Publication: 2022).

Publication Type: Clinical Trial; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7374 (Electronic) Linking ISSN: 15537366 NLM ISO Abbreviation: PLoS Pathog Subsets: MEDLINE

The One That Got Away: How Macrophage-Derived IL-1β Escapes the Mycolactone-Dependent Sec61 Blockade in Buruli Ulcer.

Authors: Hall BS Hsieh LT Sacre S et al.

Source: Frontiers in immunology [Front Immunol] 2022 Jan 26; Vol. 12, pp. 788146. Date of Electronic Publication: 2022 Jan 26 (Print Publication: 2021).

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE

Mycolactone causes destructive Sec61-dependent loss of the endothelial glycocalyx and vessel basement membrane: a new indirect mechanism driving tissue necrosis in Mycobacterium ulcerans infection.

Authors: Hsieh LT Hall BS Newcombe J et al.

Source: BioRxiv : the preprint server for biology [bioRxiv] 2024 Oct 01. Date of Electronic Publication: 2024 Oct 01.

Publication Type: Journal Article; Preprint

Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

Mycolactone enhances the Ca2+ leak from endoplasmic reticulum by trapping Sec61 translocons in a Ca2+ permeable state.

Authors: Bhadra P Dos Santos S Gamayun I et al.

Source: The Biochemical journal [Biochem J] 2021 Nov 26; Vol. 478 (22), pp. 4005-4024.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Published by Portland Press on behalf of the Biochemical Society Country of Publication: England NLM ID: 2984726R Publication Model: Print Cited Medium: Internet ISSN: 1470-8728 (Electronic) Linking ISSN: 02646021 NLM ISO Abbreviation: Biochem J Subsets: MEDLINE

Nocturnal home haemodialysis: The 17 years experience of a single Australian dialysis service.

Authors: Choo SZ See EJ Simmonds RE et al.

Source: Nephrology (Carlton, Vic.) [Nephrology (Carlton)] 2019 Oct; Vol. 24 (10), pp. 1050-1055. Date of Electronic Publication: 2019 Apr 29.

Publication Type: Journal Article

Journal Info: Publisher: Blackwell Science Country of Publication: Australia NLM ID: 9615568 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1440-1797 (Electronic) Linking ISSN: 13205358 NLM ISO Abbreviation: Nephrology (Carlton) Subsets: MEDLINE

Inhibition of Sec61-dependent translocation by mycolactone uncouples the integrated stress response from ER stress, driving cytotoxicity via translational activation of ATF4.

Authors: Ogbechi J Hall BS Sbarrato T et al.

Source: Cell death & disease [Cell Death Dis] 2018 Mar 14; Vol. 9 (3), pp. 397. Date of Electronic Publication: 2018 Mar 14.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-4889 (Electronic) NLM ISO Abbreviation: Cell Death Dis Subsets: MEDLINE

Recent advances: role of mycolactone in the pathogenesis and monitoring of Mycobacterium ulcerans infection/Buruli ulcer disease.

Authors: Sarfo FS Phillips R Wansbrough-Jones M et al.

Source: Cellular microbiology [Cell Microbiol] 2016 Jan; Vol. 18 (1), pp. 17-29.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Review

Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 100883691 Publication Model: Print Cited Medium: Internet ISSN: 1462-5822 (Electronic) Linking ISSN: 14625814 NLM ISO Abbreviation: Cell Microbiol Subsets: MEDLINE

Structure of the Inhibited State of the Sec Translocon.

Authors: Gérard SF Hall BS Zaki AM et al.

Source: Molecular cell [Mol Cell] 2020 Aug 06; Vol. 79 (3), pp. 406-415.e7. Date of Electronic Publication: 2020 Jul 09.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 9802571 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4164 (Electronic) Linking ISSN: 10972765 NLM ISO Abbreviation: Mol Cell Subsets: MEDLINE

Mycolactone-Dependent Depletion of Endothelial Cell Thrombomodulin Is Strongly Associated with Fibrin Deposition in Buruli Ulcer Lesions.

Authors: Ogbechi J Ruf MT Hall BS et al.

Source: PLoS pathogens [PLoS Pathog] 2015 Jul 16; Vol. 11 (7), pp. e1005011. Date of Electronic Publication: 2015 Jul 16 (Print Publication: 2015).

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7374 (Electronic) Linking ISSN: 15537366 NLM ISO Abbreviation: PLoS Pathog Subsets: MEDLINE

The pathogenic mechanism of the Mycobacterium ulcerans virulence factor, mycolactone, depends on blockade of protein translocation into the ER.

Authors: Hall BS Hill K McKenna M et al.

Source: PLoS pathogens [PLoS Pathog] 2014 Apr 03; Vol. 10 (4), pp. e1004061. Date of Electronic Publication: 2014 Apr 03 (Print Publication: 2014).

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7374 (Electronic) Linking ISSN: 15537366 NLM ISO Abbreviation: PLoS Pathog Subsets: MEDLINE